[
  {
    "local_id": "C1",
    "type": "resource",
    "core": true,
    "statement": "In the audited public IBDMDB HUMAnN3 pathway tables, 375 retained paired Crohn's samples from 52 participants contain named-species PWY-5676 RNA in only 25 of 205 samples with positive community pathway RNA, and the preregistered sustained-contributor-decline analysis yields six episodes from five participants with zero reported alternative-species RNA at all three visits, preventing this operational analysis from distinguishing biological compensation failure from unresolved transcription.",
    "evidence": [
      {
        "result": "R1.cohorts.CD",
        "produced_by": "code/analyze.py"
      },
      {
        "result": "R1.coverage.PWY-5676.MTX3",
        "produced_by": "code/analyze.py"
      },
      {
        "result": "R1.analyses.PWY-5676.CD",
        "produced_by": "code/analyze.py"
      },
      {
        "result": "R3.decline_events_with_zero_alternative_rna_all_visits",
        "produced_by": "code/validate.py"
      }
    ],
    "depends_on": [],
    "falsified_if": "A rerun of the specified official source bytes yields different cohort, attribution, or episode counts, or direct raw-row inspection finds positive named alternative RNA in a declared decline episode.",
    "confidence": 0.98
  }
]