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"cardiac disorders", "infections and infestations", "metabolism and nutrition disorders", "respiratory, thoracic and mediastinal disorders" ], "tested": 27 }, "preferred_terms": { "discovered": [ "Acute myocardial infarction", "Cellulitis" ], "items": { "Abdominal hernia": { "all": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 93765, "hi": 1.49937, "lo": 0.577505, "log_rr": -0.0719969, "p": 0.767378, "placebo_affected": 33, "placebo_at_risk": 67544, "rr": 0.930534, "se": 0.243393, "se_clustered": 0.177136, "se_greenland_robins": 0.243393, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 1.75688, "lo": 0.375364, "log_rr": -0.208159, "p": 0.597026, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.812078, "se": 0.393732, "se_clustered": 0.316711, "se_greenland_robins": 0.393732, "strata_with_events": 6, "trials": 117, 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0.481056, "placebo_affected": 397, "placebo_at_risk": 35018, "rr": 0.936498, "se": 0.0931134, "se_clustered": 0.0931134, "se_greenland_robins": 0.0711862, "strata_with_events": 28, "trials": 117, "trials_with_events": 27 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 289, "glp1_at_risk": 46377, "hi": 1.08715, "lo": 0.787971, "log_rr": -0.0773652, "p": 0.346071, "placebo_affected": 291, "placebo_at_risk": 32526, "rr": 0.925552, "se": 0.082108, "se_clustered": 0.0543869, "se_greenland_robins": 0.082108, "strata_with_events": 24, "trials": 117, "trials_with_events": 24 } }, "Acute left ventricular failure": { "all": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 1.3457, "lo": 0.505372, "log_rr": -0.192775, "p": 0.440363, "placebo_affected": 36, "placebo_at_risk": 67544, "rr": 0.824668, "se": 0.249844, "se_clustered": 0.208867, "se_greenland_robins": 0.249844, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 47388, "hi": 1.34303, "lo": 0.434947, "log_rr": -0.2688, "p": 0.350017, "placebo_affected": 28, "placebo_at_risk": 35018, "rr": 0.764296, "se": 0.287623, "se_clustered": 0.204682, "se_greenland_robins": 0.287623, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 4.0597, "lo": 0.264342, "log_rr": 0.0352991, "p": 0.959601, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.03593, "se": 0.696855, "se_clustered": 0.696855, "se_greenland_robins": 0.508503, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Acute myeloid leukaemia": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.61009, "lo": 0.317563, "log_rr": -0.335394, "p": 0.418013, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.715056, "se": 0.414132, "se_clustered": 0.367612, "se_greenland_robins": 0.414132, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 3.10401, "lo": 0.322729, "log_rr": 0.000875137, "p": 0.998791, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.00088, "se": 0.577469, "se_clustered": 0.271387, "se_greenland_robins": 0.577469, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.80706, "lo": 0.138705, "log_rr": -0.691854, "p": 0.290764, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.500647, "se": 0.654887, "se_clustered": 0.654887, "se_greenland_robins": 0.6125, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Acute myocardial infarction": { "all": { "clustered_wider": false, "glp1_affected": 750, "glp1_at_risk": 93765, "hi": 0.830756, "lo": 0.687347, "log_rr": -0.280168, "p": 6.81088e-09, "placebo_affected": 946, "placebo_at_risk": 67544, "rr": 0.755657, "se": 0.0483421, "se_clustered": 0.0299189, "se_greenland_robins": 0.0483421, "strata_with_events": 70, "trials": 234, "trials_with_events": 70 }, "discovered": true, "discovery": { "clustered_wider": false, "glp1_affected": 588, "glp1_at_risk": 47388, "hi": 0.84204, "lo": 0.681664, "log_rr": -0.277573, "p": 2.61008e-07, "placebo_affected": 761, "placebo_at_risk": 35018, "rr": 0.75762, "se": 0.0539017, "se_clustered": 0.0360581, "se_greenland_robins": 0.0539017, "strata_with_events": 35, "trials": 117, "trials_with_events": 35 }, "discovery_q": 0.00013468, "merged_rows": { "groups": 0, "participants": 0 }, "replicated": true, "replication": { "clustered_wider": false, "glp1_affected": 162, "glp1_at_risk": 46377, "hi": 0.926403, "lo": 0.603624, "log_rr": -0.290625, "p": 0.00782496, "placebo_affected": 185, "placebo_at_risk": 32526, "rr": 0.747796, "se": 0.109277, "se_clustered": 0.0420148, "se_greenland_robins": 0.109277, "strata_with_events": 35, "trials": 117, "trials_with_events": 35 } }, "Acute pulmonary oedema": { "all": { "clustered_wider": true, "glp1_affected": 51, "glp1_at_risk": 93765, "hi": 1.22733, "lo": 0.556458, "log_rr": -0.190661, "p": 0.344738, "placebo_affected": 61, "placebo_at_risk": 67544, "rr": 0.826413, "se": 0.20179, "se_clustered": 0.20179, "se_greenland_robins": 0.189457, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 47388, "hi": 1.45799, "lo": 0.58258, "log_rr": -0.0816152, "p": 0.727276, "placebo_affected": 38, "placebo_at_risk": 35018, "rr": 0.921627, "se": 0.234021, "se_clustered": 0.175596, "se_greenland_robins": 0.234021, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 1.71279, "lo": 0.263198, "log_rr": -0.398362, "p": 0.404434, "placebo_affected": 23, "placebo_at_risk": 32526, "rr": 0.671419, "se": 0.477808, "se_clustered": 0.477808, "se_greenland_robins": 0.325398, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Acute respiratory distress syndrome": { "all": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.46552, "lo": 0.256586, "log_rr": -0.489042, "p": 0.271269, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.613214, "se": 0.444524, "se_clustered": 0.23965, "se_greenland_robins": 0.444524, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.73767, "lo": 0.268302, "log_rr": -0.381548, "p": 0.423373, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.682804, "se": 0.476587, "se_clustered": 0.256621, "se_greenland_robins": 0.476587, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 3.92064, "lo": 0.0207501, "log_rr": -1.25447, "p": 0.34815, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 0.285226, "se": 1.33713, "se_clustered": 0.85573, "se_greenland_robins": 1.33713, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Acute respiratory failure": { "all": { "clustered_wider": false, "glp1_affected": 164, "glp1_at_risk": 93765, "hi": 0.940404, "lo": 0.619963, "log_rr": -0.26977, "p": 0.011147, "placebo_affected": 204, "placebo_at_risk": 67544, "rr": 0.763555, "se": 0.10629, "se_clustered": 0.106062, "se_greenland_robins": 0.10629, "strata_with_events": 27, "trials": 234, "trials_with_events": 27 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 100, "glp1_at_risk": 47388, "hi": 0.987679, "lo": 0.580613, "log_rr": -0.278034, "p": 0.0402246, "placebo_affected": 126, "placebo_at_risk": 35018, "rr": 0.757271, "se": 0.135531, "se_clustered": 0.134142, "se_greenland_robins": 0.135531, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.506242, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 64, "glp1_at_risk": 46377, "hi": 1.09492, "lo": 0.54672, "log_rr": -0.256567, "p": 0.147582, "placebo_affected": 78, "placebo_at_risk": 32526, "rr": 0.773703, "se": 0.177172, "se_clustered": 0.177172, "se_greenland_robins": 0.171318, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Adenocarcinoma gastric": { "all": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 1.70893, "lo": 0.613022, "log_rr": 0.0232579, "p": 0.929141, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 1.02353, "se": 0.261542, "se_clustered": 0.212443, "se_greenland_robins": 0.261542, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.09732, "lo": 0.4769, "log_rr": 0.000106058, "p": 0.999776, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 1.00011, "se": 0.377841, "se_clustered": 0.159671, "se_greenland_robins": 0.377841, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 2.31705, "lo": 0.471667, "log_rr": 0.0444077, "p": 0.912918, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 1.04541, "se": 0.406073, "se_clustered": 0.406073, "se_greenland_robins": 0.362432, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Adenocarcinoma of colon": 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"se": 0.222787, "se_clustered": 0.168555, "se_greenland_robins": 0.222787, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Adenocarcinoma pancreas": { "all": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 2.39186, "lo": 0.680125, "log_rr": 0.243297, "p": 0.448222, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.27545, "se": 0.32081, "se_clustered": 0.303244, "se_greenland_robins": 0.32081, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.29025, "lo": 0.506572, "log_rr": 0.0742865, "p": 0.846954, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.07712, "se": 0.384892, "se_clustered": 0.350518, "se_greenland_robins": 0.384892, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.956298, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 6.14708, "lo": 0.569189, "log_rr": 0.626218, "p": 0.302256, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.87052, "se": 0.607031, "se_clustered": 0.607031, "se_greenland_robins": 0.595905, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Alanine aminotransferase increased": { "all": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 93765, "hi": 1.2735, "lo": 0.186679, "log_rr": -0.718295, "p": 0.142542, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.487583, "se": 0.48984, "se_clustered": 0.35611, "se_greenland_robins": 0.48984, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.2632, "lo": 0.142985, "log_rr": -0.855684, "p": 0.123662, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.424992, "se": 0.55579, "se_clustered": 0.320203, "se_greenland_robins": 0.55579, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.669269, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 8.17831, "lo": 0.0845851, "log_rr": -0.184256, "p": 0.874461, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 0.831723, "se": 1.16622, "se_clustered": 1.16622, "se_greenland_robins": 1.08078, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Anaemia": { "all": { "clustered_wider": true, "glp1_affected": 204, "glp1_at_risk": 93765, "hi": 1.15272, "lo": 0.739607, "log_rr": -0.0797561, "p": 0.48111, "placebo_affected": 212, "placebo_at_risk": 67544, "rr": 0.923342, "se": 0.113207, "se_clustered": 0.113207, "se_greenland_robins": 0.0980586, "strata_with_events": 28, "trials": 234, "trials_with_events": 28 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 115, "glp1_at_risk": 47388, "hi": 1.28832, "lo": 0.707839, "log_rr": -0.0461005, "p": 0.762843, "placebo_affected": 118, "placebo_at_risk": 35018, "rr": 0.954946, "se": 0.152777, "se_clustered": 0.152777, "se_greenland_robins": 0.130005, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 89, "glp1_at_risk": 46377, "hi": 1.23262, "lo": 0.633561, "log_rr": -0.123629, "p": 0.466519, "placebo_affected": 94, "placebo_at_risk": 32526, "rr": 0.883708, "se": 0.169784, "se_clustered": 0.169784, "se_greenland_robins": 0.149407, "strata_with_events": 15, "trials": 117, "trials_with_events": 15 } }, "Anal abscess": { "all": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 2.71008, "lo": 0.508617, "log_rr": 0.160458, "p": 0.706952, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.17405, "se": 0.426803, "se_clustered": 0.426803, "se_greenland_robins": 0.337417, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 6.31596, "lo": 0.707491, "log_rr": 0.748525, "p": 0.180133, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 2.11388, "se": 0.558456, "se_clustered": 0.558456, "se_greenland_robins": 0.504928, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 1.99196, "lo": 0.219626, "log_rr": -0.413354, "p": 0.462428, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 0.661428, "se": 0.562498, "se_clustered": 0.562498, "se_greenland_robins": 0.490154, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Anal fistula": { "all": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 93765, "hi": 0.934042, "lo": 0.126135, "log_rr": -1.06932, "p": 0.0362997, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.343243, "se": 0.510767, "se_clustered": 0.41697, "se_greenland_robins": 0.510767, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 0.803713, "lo": 0.0697853, "log_rr": -1.44042, "p": 0.0208625, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.236828, "se": 0.623435, "se_clustered": 0.415237, "se_greenland_robins": 0.623435, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.371387, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 7.9886, "lo": 0.129767, "log_rr": 0.0180004, "p": 0.986336, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 1.01816, "se": 1.05105, "se_clustered": 1.04996, "se_greenland_robins": 1.05105, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Anaphylactic reaction": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.49414, "lo": 0.292926, "log_rr": -0.413143, "p": 0.320257, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.661567, "se": 0.415666, "se_clustered": 0.370597, "se_greenland_robins": 0.415666, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 1.84891, "lo": 0.214561, "log_rr": -0.462282, "p": 0.40014, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.629845, "se": 0.549438, "se_clustered": 0.404793, "se_greenland_robins": 0.549438, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.94417, "lo": 0.170613, "log_rr": -0.344266, "p": 0.635635, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.70874, "se": 0.726591, "se_clustered": 0.726591, "se_greenland_robins": 0.635869, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Angina pectoris": { "all": { "clustered_wider": false, "glp1_affected": 504, "glp1_at_risk": 93765, "hi": 1.00513, "lo": 0.787674, "log_rr": -0.116776, "p": 0.0604272, "placebo_affected": 537, "placebo_at_risk": 67544, "rr": 0.889784, "se": 0.0621924, "se_clustered": 0.0533236, "se_greenland_robins": 0.0621924, "strata_with_events": 39, "trials": 234, "trials_with_events": 39 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 336, "glp1_at_risk": 47388, "hi": 1.01203, "lo": 0.755491, "log_rr": -0.134213, "p": 0.0719278, "placebo_affected": 380, "placebo_at_risk": 35018, "rr": 0.874404, "se": 0.0745802, "se_clustered": 0.0649406, "se_greenland_robins": 0.0745802, "strata_with_events": 18, "trials": 117, "trials_with_events": 18 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 168, "glp1_at_risk": 46377, "hi": 1.15452, "lo": 0.742194, "log_rr": -0.0772286, "p": 0.493236, "placebo_affected": 157, "placebo_at_risk": 32526, "rr": 0.925678, "se": 0.112714, "se_clustered": 0.0769969, "se_greenland_robins": 0.112714, "strata_with_events": 21, "trials": 117, "trials_with_events": 21 } }, "Angina unstable": { "all": { "clustered_wider": false, "glp1_affected": 588, "glp1_at_risk": 93765, "hi": 0.953581, "lo": 0.763442, "log_rr": -0.158725, "p": 0.00514577, "placebo_affected": 647, "placebo_at_risk": 67544, "rr": 0.853231, "se": 0.0567326, "se_clustered": 0.0415739, "se_greenland_robins": 0.0567326, "strata_with_events": 49, "trials": 234, "trials_with_events": 49 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 450, "glp1_at_risk": 47388, "hi": 1.0121, "lo": 0.785589, "log_rr": -0.114648, "p": 0.0760819, "placebo_affected": 494, "placebo_at_risk": 35018, "rr": 0.89168, "se": 0.0646308, "se_clustered": 0.0414025, "se_greenland_robins": 0.0646308, "strata_with_events": 26, "trials": 117, "trials_with_events": 26 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 138, "glp1_at_risk": 46377, "hi": 0.929307, "lo": 0.583219, "log_rr": -0.306254, "p": 0.00997054, "placebo_affected": 153, "placebo_at_risk": 32526, "rr": 0.7362, "se": 0.118848, "se_clustered": 0.0682525, "se_greenland_robins": 0.118848, "strata_with_events": 23, "trials": 117, "trials_with_events": 23 } }, "Angioedema": { "all": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 1.49239, "lo": 0.474565, "log_rr": -0.172489, "p": 0.555096, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 0.841568, "se": 0.292284, "se_clustered": 0.195276, "se_greenland_robins": 0.292284, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.42774, "lo": 0.252244, "log_rr": -0.510632, "p": 0.248207, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.600116, "se": 0.442215, "se_clustered": 0.351699, "se_greenland_robins": 0.442215, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 2.39551, "lo": 0.504551, "log_rr": 0.0947561, "p": 0.811528, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.09939, "se": 0.397376, "se_clustered": 0.305182, "se_greenland_robins": 0.397376, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Angioplasty": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.65926, "lo": 0.354809, "log_rr": -0.2649, "p": 0.500842, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.767282, "se": 0.393515, "se_clustered": 0.218463, "se_greenland_robins": 0.393515, "strata_with_events": 4, "trials": 234, "trials_with_events": 4 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.82977, "lo": 0.357116, "log_rr": -0.212751, "p": 0.609758, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.808358, "se": 0.416816, "se_clustered": 0.278789, "se_greenland_robins": 0.416816, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 5.51209, "lo": 0.0454099, "log_rr": -0.692541, "p": 0.571607, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 0.500303, "se": 1.22425, "se_clustered": null, "se_greenland_robins": 1.22425, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 } }, "Ankle fracture": { "all": { "clustered_wider": true, "glp1_affected": 72, "glp1_at_risk": 93765, "hi": 1.0377, "lo": 0.534973, "log_rr": -0.294265, "p": 0.0816825, "placebo_affected": 83, "placebo_at_risk": 67544, "rr": 0.745079, "se": 0.16902, "se_clustered": 0.16902, "se_greenland_robins": 0.161725, "strata_with_events": 33, "trials": 234, "trials_with_events": 32 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 26, "glp1_at_risk": 47388, "hi": 1.008, "lo": 0.351214, "log_rr": -0.519198, "p": 0.0535627, "placebo_affected": 37, "placebo_at_risk": 35018, "rr": 0.594998, "se": 0.268965, "se_clustered": 0.178165, "se_greenland_robins": 0.268965, "strata_with_events": 17, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.575799, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 46, "glp1_at_risk": 46377, "hi": 1.27867, "lo": 0.576266, "log_rr": -0.152682, "p": 0.452691, "placebo_affected": 46, "placebo_at_risk": 32526, "rr": 0.858403, "se": 0.203322, "se_clustered": 0.190005, "se_greenland_robins": 0.203322, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 } }, "Anxiety": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 3.01332, "lo": 0.651049, "log_rr": 0.336936, "p": 0.388688, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.40065, "se": 0.390878, "se_clustered": 0.3196, "se_greenland_robins": 0.390878, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 4.0665, "lo": 0.661451, "log_rr": 0.494731, "p": 0.285591, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.64006, "se": 0.463299, "se_clustered": 0.297617, "se_greenland_robins": 0.463299, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.823828, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 4.14707, "lo": 0.223015, "log_rr": -0.039057, "p": 0.958226, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 0.961696, "se": 0.745656, "se_clustered": 0.737085, "se_greenland_robins": 0.745656, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Aortic aneurysm": { "all": { "clustered_wider": true, "glp1_affected": 51, "glp1_at_risk": 93765, "hi": 1.91484, "lo": 0.804638, "log_rr": 0.216137, "p": 0.328465, "placebo_affected": 40, "placebo_at_risk": 67544, "rr": 1.24127, "se": 0.221177, "se_clustered": 0.221177, "se_greenland_robins": 0.208973, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 33, "glp1_at_risk": 47388, "hi": 1.74039, "lo": 0.65875, "log_rr": 0.0683478, "p": 0.782723, "placebo_affected": 30, "placebo_at_risk": 35018, "rr": 1.07074, "se": 0.247841, "se_clustered": 0.137344, "se_greenland_robins": 0.247841, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 6.17619, "lo": 0.505316, "log_rr": 0.569065, "p": 0.37287, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.76661, "se": 0.638602, "se_clustered": 0.638602, "se_greenland_robins": 0.397002, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Aortic dissection": { "all": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 5.34711, "lo": 0.747929, "log_rr": 0.693055, "p": 0.167233, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.99982, "se": 0.501796, "se_clustered": 0.501796, "se_greenland_robins": 0.43295, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 6.00614, "lo": 0.539485, "log_rr": 0.587821, "p": 0.339003, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 1.80006, "se": 0.614788, "se_clustered": 0.614788, "se_greenland_robins": 0.557659, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 14.0479, "lo": 0.387361, "log_rr": 0.847038, "p": 0.355144, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.33273, "se": 0.916056, "se_clustered": 0.916056, "se_greenland_robins": 0.690016, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Aortic stenosis": { "all": { "clustered_wider": true, "glp1_affected": 59, "glp1_at_risk": 93765, "hi": 1.67628, "lo": 0.562613, "log_rr": -0.0292941, "p": 0.916232, "placebo_affected": 58, "placebo_at_risk": 67544, "rr": 0.971131, "se": 0.27851, "se_clustered": 0.27851, "se_greenland_robins": 0.184776, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 47388, "hi": 1.67443, "lo": 0.266245, "log_rr": -0.403933, "p": 0.389187, "placebo_affected": 32, "placebo_at_risk": 35018, "rr": 0.667689, "se": 0.469093, "se_clustered": 0.469093, "se_greenland_robins": 0.278209, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 46377, "hi": 2.19628, "lo": 0.811887, "log_rr": 0.289187, "p": 0.25466, "placebo_affected": 26, "placebo_at_risk": 32526, "rr": 1.33534, "se": 0.253872, "se_clustered": 0.158993, "se_greenland_robins": 0.253872, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Aortic valve incompetence": { "all": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 2.49877, "lo": 0.318335, "log_rr": -0.114425, "p": 0.827671, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.891879, "se": 0.525635, "se_clustered": 0.525635, "se_greenland_robins": 0.432121, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.58753, "lo": 0.149311, "log_rr": -0.719775, "p": 0.23265, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.486862, "se": 0.603048, "se_clustered": 0.533434, "se_greenland_robins": 0.603048, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 8.94817, "lo": 0.447473, "log_rr": 0.693654, "p": 0.36404, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.00101, "se": 0.764195, "se_clustered": 0.764195, "se_greenland_robins": 0.706858, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Aortic valve stenosis": { "all": { "clustered_wider": false, "glp1_affected": 56, "glp1_at_risk": 93765, "hi": 1.53763, "lo": 0.714656, "log_rr": 0.0471461, "p": 0.809398, "placebo_affected": 51, "placebo_at_risk": 67544, "rr": 1.04828, "se": 0.195462, "se_clustered": 0.133117, "se_greenland_robins": 0.195462, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 40, "glp1_at_risk": 47388, "hi": 1.53617, "lo": 0.633699, "log_rr": -0.0134452, "p": 0.952537, "placebo_affected": 39, "placebo_at_risk": 35018, "rr": 0.986645, "se": 0.22589, "se_clustered": 0.137531, "se_greenland_robins": 0.22589, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 2.69515, "lo": 0.580046, "log_rr": 0.223403, "p": 0.568613, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.25032, "se": 0.39187, "se_clustered": 0.348804, "se_greenland_robins": 0.39187, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Appendicitis": { "all": { "clustered_wider": false, "glp1_affected": 111, "glp1_at_risk": 93765, "hi": 1.54907, "lo": 0.843898, "log_rr": 0.133966, "p": 0.387261, "placebo_affected": 73, "placebo_at_risk": 67544, "rr": 1.14335, "se": 0.154947, "se_clustered": 0.14465, "se_greenland_robins": 0.154947, "strata_with_events": 52, "trials": 234, "trials_with_events": 51 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 68, "glp1_at_risk": 47388, "hi": 1.68353, "lo": 0.778721, "log_rr": 0.135395, "p": 0.491212, "placebo_affected": 45, "placebo_at_risk": 35018, "rr": 1.14499, "se": 0.196686, "se_clustered": 0.158284, "se_greenland_robins": 0.196686, "strata_with_events": 28, "trials": 117, "trials_with_events": 27 }, "discovery_q": 0.859206, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 43, "glp1_at_risk": 46377, "hi": 1.98919, "lo": 0.654172, "log_rr": 0.131672, "p": 0.642568, "placebo_affected": 28, "placebo_at_risk": 32526, "rr": 1.14073, "se": 0.283708, "se_clustered": 0.283708, "se_greenland_robins": 0.251529, "strata_with_events": 24, "trials": 117, "trials_with_events": 24 } }, "Appendicitis perforated": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.02591, "lo": 0.42929, "log_rr": -0.0698006, "p": 0.860029, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.93258, "se": 0.395835, "se_clustered": 0.293446, "se_greenland_robins": 0.395835, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.61578, "lo": 0.283601, "log_rr": -0.390185, "p": 0.379391, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.676932, "se": 0.443887, "se_clustered": 0.441771, "se_greenland_robins": 0.443887, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 38.9447, "lo": 0.401986, "log_rr": 1.3754, "p": 0.238455, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 3.95667, "se": 1.16673, "se_clustered": 0.948408, "se_greenland_robins": 1.16673, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Arrhythmia": { "all": { "clustered_wider": false, "glp1_affected": 42, "glp1_at_risk": 93765, "hi": 1.89015, "lo": 0.766944, "log_rr": 0.185657, "p": 0.419761, "placebo_affected": 34, "placebo_at_risk": 67544, "rr": 1.20401, "se": 0.230106, "se_clustered": 0.155989, "se_greenland_robins": 0.230106, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 47388, "hi": 2.45369, "lo": 0.799036, "log_rr": 0.336621, "p": 0.239549, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.40021, "se": 0.286215, "se_clustered": 0.159023, "se_greenland_robins": 0.286215, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 1.93619, "lo": 0.414964, "log_rr": -0.109421, "p": 0.780653, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 0.896353, "se": 0.392937, "se_clustered": 0.370117, "se_greenland_robins": 0.392937, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Arteriosclerosis": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.07764, "lo": 0.33108, "log_rr": -0.51531, "p": 0.0869701, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 0.597315, "se": 0.301069, "se_clustered": 0.199693, "se_greenland_robins": 0.301069, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.23578, "lo": 0.310187, "log_rr": -0.479439, "p": 0.173954, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.619131, "se": 0.35263, "se_clustered": 0.163612, "se_greenland_robins": 0.35263, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.69576, "lo": 0.176111, "log_rr": -0.604254, "p": 0.295627, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.546482, "se": 0.577759, "se_clustered": 0.551228, "se_greenland_robins": 0.577759, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Arteriosclerosis coronary artery": { "all": { "clustered_wider": false, "glp1_affected": 55, "glp1_at_risk": 93765, "hi": 1.47594, "lo": 0.679524, "log_rr": 0.00146749, "p": 0.994083, "placebo_affected": 51, "placebo_at_risk": 67544, "rr": 1.00147, "se": 0.197876, "se_clustered": 0.172597, "se_greenland_robins": 0.197876, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 47388, "hi": 1.75511, "lo": 0.677135, "log_rr": 0.0863231, "p": 0.722375, "placebo_affected": 32, "placebo_at_risk": 35018, "rr": 1.09016, "se": 0.242968, "se_clustered": 0.228951, "se_greenland_robins": 0.242968, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 1.66333, "lo": 0.434086, "log_rr": -0.162845, "p": 0.634651, "placebo_affected": 19, "placebo_at_risk": 32526, "rr": 0.849723, "se": 0.342693, "se_clustered": 0.219587, "se_greenland_robins": 0.342693, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Arthralgia": { "all": { "clustered_wider": true, "glp1_affected": 64, "glp1_at_risk": 93765, "hi": 1.3827, "lo": 0.607796, "log_rr": -0.0869392, "p": 0.678423, "placebo_affected": 61, "placebo_at_risk": 67544, "rr": 0.916733, "se": 0.209686, "se_clustered": 0.209686, "se_greenland_robins": 0.179546, "strata_with_events": 23, "trials": 234, "trials_with_events": 22 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 44, "glp1_at_risk": 47388, "hi": 1.62954, "lo": 0.598416, "log_rr": -0.0125854, "p": 0.960723, "placebo_affected": 39, "placebo_at_risk": 35018, "rr": 0.987493, "se": 0.255558, "se_clustered": 0.255558, "se_greenland_robins": 0.221036, "strata_with_events": 13, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 46377, "hi": 1.59706, "lo": 0.39303, "log_rr": -0.232854, "p": 0.515025, "placebo_affected": 22, "placebo_at_risk": 32526, "rr": 0.792269, "se": 0.357668, "se_clustered": 0.357668, "se_greenland_robins": 0.309067, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Arthritis": { "all": { "clustered_wider": true, "glp1_affected": 45, "glp1_at_risk": 93765, "hi": 1.93496, "lo": 0.592119, "log_rr": 0.0680198, "p": 0.821846, "placebo_affected": 40, "placebo_at_risk": 67544, "rr": 1.07039, "se": 0.302081, "se_clustered": 0.302081, "se_greenland_robins": 0.211968, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 30, "glp1_at_risk": 47388, "hi": 3.11343, "lo": 0.564271, "log_rr": 0.281751, "p": 0.517858, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.32545, "se": 0.435708, "se_clustered": 0.435708, "se_greenland_robins": 0.274633, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.872335, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 1.53439, "lo": 0.392329, "log_rr": -0.253761, "p": 0.465766, "placebo_affected": 19, "placebo_at_risk": 32526, "rr": 0.775877, "se": 0.347911, "se_clustered": 0.347911, "se_greenland_robins": 0.340567, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Arthritis bacterial": { "all": { "clustered_wider": true, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 1.77474, "lo": 0.482824, "log_rr": -0.0772231, "p": 0.81612, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 0.925683, "se": 0.332087, "se_clustered": 0.332087, "se_greenland_robins": 0.323445, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 2.35568, "lo": 0.382684, "log_rr": -0.0518585, "p": 0.910939, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.949463, "se": 0.463625, "se_clustered": 0.45955, "se_greenland_robins": 0.463625, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.978839, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 2.53246, "lo": 0.321753, "log_rr": -0.10239, "p": 0.845755, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.902677, "se": 0.526327, "se_clustered": 0.526327, "se_greenland_robins": 0.451295, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Ascites": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.52577, "lo": 0.311512, "log_rr": -0.371908, "p": 0.358842, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.689417, "se": 0.405317, "se_clustered": 0.292958, "se_greenland_robins": 0.405317, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.84256, "lo": 0.202831, "log_rr": -0.492111, "p": 0.381988, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.611334, "se": 0.562903, "se_clustered": 0.398422, "se_greenland_robins": 0.562903, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.49362, "lo": 0.250481, "log_rr": -0.235318, "p": 0.688135, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.79032, "se": 0.586263, "se_clustered": 0.468511, "se_greenland_robins": 0.586263, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Asthenia": { "all": { "clustered_wider": false, "glp1_affected": 58, "glp1_at_risk": 93765, "hi": 1.86659, "lo": 0.844733, "log_rr": 0.227689, "p": 0.260283, "placebo_affected": 44, "placebo_at_risk": 67544, "rr": 1.2557, "se": 0.202261, "se_clustered": 0.176285, "se_greenland_robins": 0.202261, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 47388, "hi": 3.20657, "lo": 1.04742, "log_rr": 0.605768, "p": 0.033813, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 1.83266, "se": 0.28543, "se_clustered": 0.259155, "se_greenland_robins": 0.28543, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.447371, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 46377, "hi": 1.47711, "lo": 0.458373, "log_rr": -0.194994, "p": 0.513619, "placebo_affected": 25, "placebo_at_risk": 32526, "rr": 0.82284, "se": 0.298515, "se_clustered": 0.189466, "se_greenland_robins": 0.298515, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Asthma": { "all": { "clustered_wider": true, "glp1_affected": 64, "glp1_at_risk": 93765, "hi": 1.41715, "lo": 0.597661, "log_rr": -0.0830408, "p": 0.706157, "placebo_affected": 61, "placebo_at_risk": 67544, "rr": 0.920314, "se": 0.220254, "se_clustered": 0.220254, "se_greenland_robins": 0.182154, "strata_with_events": 32, "trials": 234, "trials_with_events": 31 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 39, "glp1_at_risk": 47388, "hi": 1.67717, "lo": 0.471391, "log_rr": -0.11748, "p": 0.716722, "placebo_affected": 39, "placebo_at_risk": 35018, "rr": 0.889159, "se": 0.323775, "se_clustered": 0.323775, "se_greenland_robins": 0.231031, "strata_with_events": 18, "trials": 117, "trials_with_events": 17 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 46377, "hi": 1.74184, "lo": 0.545204, "log_rr": -0.0258267, "p": 0.930545, "placebo_affected": 22, "placebo_at_risk": 32526, "rr": 0.974504, "se": 0.296316, "se_clustered": 0.246297, "se_greenland_robins": 0.296316, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Atrial fibrillation": { "all": { "clustered_wider": true, "glp1_affected": 625, "glp1_at_risk": 93765, "hi": 1.11176, "lo": 0.837938, "log_rr": -0.0354331, "p": 0.623272, "placebo_affected": 604, "placebo_at_risk": 67544, "rr": 0.965187, "se": 0.0721332, "se_clustered": 0.0721332, "se_greenland_robins": 0.056944, "strata_with_events": 55, "trials": 234, "trials_with_events": 53 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 383, "glp1_at_risk": 47388, "hi": 1.00807, "lo": 0.764806, "log_rr": -0.130045, "p": 0.0649194, "placebo_affected": 417, "placebo_at_risk": 35018, "rr": 0.878055, "se": 0.0704543, "se_clustered": 0.0564139, "se_greenland_robins": 0.0704543, "strata_with_events": 29, "trials": 117, "trials_with_events": 28 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 242, "glp1_at_risk": 46377, "hi": 1.46567, "lo": 0.90944, "log_rr": 0.143694, "p": 0.237895, "placebo_affected": 187, "placebo_at_risk": 32526, "rr": 1.15453, "se": 0.121747, "se_clustered": 0.121747, "se_greenland_robins": 0.0972964, "strata_with_events": 26, "trials": 117, "trials_with_events": 25 } }, "Atrial flutter": { "all": { "clustered_wider": false, "glp1_affected": 108, "glp1_at_risk": 93765, "hi": 1.11833, "lo": 0.659386, "log_rr": -0.152304, "p": 0.258428, "placebo_affected": 114, "placebo_at_risk": 67544, "rr": 0.858727, "se": 0.134769, "se_clustered": 0.11735, "se_greenland_robins": 0.134769, "strata_with_events": 27, "trials": 234, "trials_with_events": 27 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 60, "glp1_at_risk": 47388, "hi": 1.23843, "lo": 0.622792, "log_rr": -0.12985, "p": 0.459, "placebo_affected": 66, "placebo_at_risk": 35018, "rr": 0.878227, "se": 0.175356, "se_clustered": 0.127367, "se_greenland_robins": 0.175356, "strata_with_events": 15, "trials": 117, "trials_with_events": 15 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 48, "glp1_at_risk": 46377, "hi": 1.27002, "lo": 0.545167, "log_rr": -0.183816, "p": 0.394206, "placebo_affected": 48, "placebo_at_risk": 32526, "rr": 0.832089, "se": 0.215742, "se_clustered": 0.215742, "se_greenland_robins": 0.210639, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Atrial tachycardia": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 1.98544, "lo": 0.311982, "log_rr": -0.239484, "p": 0.611973, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.787034, "se": 0.472114, "se_clustered": 0.472114, "se_greenland_robins": 0.377471, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.12975, "lo": 0.159814, "log_rr": -0.538868, "p": 0.414701, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.583408, "se": 0.660662, "se_clustered": 0.660662, "se_greenland_robins": 0.475535, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 5.37457, "lo": 0.3924, "log_rr": 0.373102, "p": 0.57628, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 1.45223, "se": 0.667653, "se_clustered": 0.667653, "se_greenland_robins": 0.660545, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Atrioventricular block": { "all": { "clustered_wider": true, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 2.9596, "lo": 0.621607, "log_rr": 0.304805, "p": 0.443879, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.35636, "se": 0.398095, "se_clustered": 0.398095, "se_greenland_robins": 0.342404, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 11.8881, "lo": 0.272994, "log_rr": 0.588619, "p": 0.540932, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 1.8015, "se": 0.962733, "se_clustered": 0.962733, "se_greenland_robins": 0.55769, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.888925, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.67633, "lo": 0.480316, "log_rr": 0.125569, "p": 0.774458, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.13379, "se": 0.438212, "se_clustered": 0.353832, "se_greenland_robins": 0.438212, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Atrioventricular block complete": { "all": { "clustered_wider": true, "glp1_affected": 67, "glp1_at_risk": 93765, "hi": 1.31886, "lo": 0.640854, "log_rr": -0.0840929, "p": 0.647859, "placebo_affected": 67, "placebo_at_risk": 67544, "rr": 0.919346, "se": 0.184116, "se_clustered": 0.184116, "se_greenland_robins": 0.173162, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 47388, "hi": 1.47653, "lo": 0.581261, "log_rr": -0.0764298, "p": 0.747928, "placebo_affected": 37, "placebo_at_risk": 35018, "rr": 0.926418, "se": 0.237823, "se_clustered": 0.222399, "se_greenland_robins": 0.237823, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 32, "glp1_at_risk": 46377, "hi": 1.70002, "lo": 0.488372, "log_rr": -0.0930187, "p": 0.770035, "placebo_affected": 30, "placebo_at_risk": 32526, "rr": 0.911176, "se": 0.318199, "se_clustered": 0.318199, "se_greenland_robins": 0.252555, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Atrioventricular block second degree": { "all": { "clustered_wider": false, "glp1_affected": 46, "glp1_at_risk": 93765, "hi": 1.64309, "lo": 0.701958, "log_rr": 0.0713483, "p": 0.742263, "placebo_affected": 40, "placebo_at_risk": 67544, "rr": 1.07396, "se": 0.216958, "se_clustered": 0.186897, "se_greenland_robins": 0.216958, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 47388, "hi": 2.18446, "lo": 0.693377, "log_rr": 0.207593, "p": 0.478249, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.23071, "se": 0.292747, "se_clustered": 0.287894, "se_greenland_robins": 0.292747, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 1.71109, "lo": 0.478207, "log_rr": -0.100291, "p": 0.757794, "placebo_affected": 19, "placebo_at_risk": 32526, "rr": 0.904574, "se": 0.32522, "se_clustered": 0.17498, "se_greenland_robins": 0.32522, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Azotaemia": { "all": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 3.37298, "lo": 0.673687, "log_rr": 0.410403, "p": 0.317922, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.50743, "se": 0.410922, "se_clustered": 0.309874, "se_greenland_robins": 0.410922, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 5.66082, "lo": 0.452386, "log_rr": 0.470174, "p": 0.465754, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.60027, "se": 0.6446, "se_clustered": 0.391912, "se_greenland_robins": 0.6446, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 4.11074, "lo": 0.507813, "log_rr": 0.367981, "p": 0.490345, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.44481, "se": 0.533491, "se_clustered": 0.474382, "se_greenland_robins": 0.533491, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "B-cell lymphoma": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 1.94312, "lo": 0.422414, "log_rr": -0.0987366, "p": 0.799789, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.905981, "se": 0.389309, "se_clustered": 0.291887, "se_greenland_robins": 0.389309, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 2.73095, "lo": 0.25443, "log_rr": -0.182041, "p": 0.763672, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.833567, "se": 0.605465, "se_clustered": 0.545206, "se_greenland_robins": 0.605465, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 2.60342, "lo": 0.354242, "log_rr": -0.040476, "p": 0.936598, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.960332, "se": 0.508836, "se_clustered": 0.372956, "se_greenland_robins": 0.508836, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Back pain": { "all": { "clustered_wider": false, "glp1_affected": 104, "glp1_at_risk": 93765, "hi": 1.03911, "lo": 0.604841, "log_rr": -0.232211, "p": 0.0925605, "placebo_affected": 114, "placebo_at_risk": 67544, "rr": 0.792779, "se": 0.138053, "se_clustered": 0.112357, "se_greenland_robins": 0.138053, "strata_with_events": 35, "trials": 234, "trials_with_events": 34 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 57, "glp1_at_risk": 47388, "hi": 0.902193, "lo": 0.449489, "log_rr": -0.451286, "p": 0.011115, "placebo_affected": 77, "placebo_at_risk": 35018, "rr": 0.636809, "se": 0.177737, "se_clustered": 0.105254, "se_greenland_robins": 0.177737, "strata_with_events": 20, "trials": 117, "trials_with_events": 19 }, "discovery_q": 0.319394, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 47, "glp1_at_risk": 46377, "hi": 1.74218, "lo": 0.72243, "log_rr": 0.115002, "p": 0.608571, "placebo_affected": 37, "placebo_at_risk": 32526, "rr": 1.12188, "se": 0.224564, "se_clustered": 0.15314, "se_greenland_robins": 0.224564, "strata_with_events": 15, "trials": 117, "trials_with_events": 15 } }, "Bacteraemia": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.24154, "lo": 0.398869, "log_rr": -0.351387, "p": 0.225102, "placebo_affected": 28, "placebo_at_risk": 67544, "rr": 0.703712, "se": 0.289667, "se_clustered": 0.25545, "se_greenland_robins": 0.289667, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.91349, "lo": 0.413547, "log_rr": -0.117027, "p": 0.764593, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.889561, "se": 0.390802, "se_clustered": 0.322785, "se_greenland_robins": 0.390802, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.2655, "lo": 0.226828, "log_rr": -0.624047, "p": 0.15473, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 0.535772, "se": 0.438537, "se_clustered": 0.337231, "se_greenland_robins": 0.438537, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Basal cell carcinoma": { "all": { "clustered_wider": true, "glp1_affected": 84, "glp1_at_risk": 93765, "hi": 1.22736, "lo": 0.67292, "log_rr": -0.09563, "p": 0.532802, "placebo_affected": 90, "placebo_at_risk": 67544, "rr": 0.9088, "se": 0.153318, "se_clustered": 0.153318, "se_greenland_robins": 0.152828, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 42, "glp1_at_risk": 47388, "hi": 1.34437, "lo": 0.483576, "log_rr": -0.215312, "p": 0.409112, "placebo_affected": 51, "placebo_at_risk": 35018, "rr": 0.80629, "se": 0.260839, "se_clustered": 0.260839, "se_greenland_robins": 0.209119, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 42, "glp1_at_risk": 46377, "hi": 1.62169, "lo": 0.67158, "log_rr": 0.0426738, "p": 0.849508, "placebo_affected": 39, "placebo_at_risk": 32526, "rr": 1.0436, "se": 0.2249, "se_clustered": 0.137979, "se_greenland_robins": 0.2249, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Benign prostatic hyperplasia": { "all": { "clustered_wider": false, "glp1_affected": 128, "glp1_at_risk": 93765, "hi": 1.49845, "lo": 0.895541, "log_rr": 0.147053, "p": 0.262791, "placebo_affected": 107, "placebo_at_risk": 67544, "rr": 1.15842, "se": 0.131319, "se_clustered": 0.118675, "se_greenland_robins": 0.131319, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 83, "glp1_at_risk": 47388, "hi": 1.74178, "lo": 0.907392, "log_rr": 0.228862, "p": 0.168891, "placebo_affected": 65, "placebo_at_risk": 35018, "rr": 1.25717, "se": 0.166351, "se_clustered": 0.149363, "se_greenland_robins": 0.166351, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 45, "glp1_at_risk": 46377, "hi": 1.53708, "lo": 0.662475, "log_rr": 0.00905629, "p": 0.966356, "placebo_affected": 42, "placebo_at_risk": 32526, "rr": 1.0091, "se": 0.214712, "se_clustered": 0.190193, "se_greenland_robins": 0.214712, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Bile duct stone": { "all": { "clustered_wider": false, "glp1_affected": 56, "glp1_at_risk": 93765, "hi": 2.34439, "lo": 0.986184, "log_rr": 0.419057, "p": 0.0578297, "placebo_affected": 34, "placebo_at_risk": 67544, "rr": 1.52053, "se": 0.220906, "se_clustered": 0.134356, "se_greenland_robins": 0.220906, "strata_with_events": 18, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 47388, "hi": 3.50108, "lo": 1.10827, "log_rr": 0.677935, "p": 0.0208725, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 1.96981, "se": 0.293442, "se_clustered": 0.19271, "se_greenland_robins": 0.293442, "strata_with_events": 11, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.371387, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 2.02561, "lo": 0.524168, "log_rr": 0.0299647, "p": 0.930759, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 1.03042, "se": 0.344857, "se_clustered": 0.186775, "se_greenland_robins": 0.344857, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Biliary colic": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 5.88104, "lo": 0.864871, "log_rr": 0.813279, "p": 0.0962938, "placebo_affected": 6, "placebo_at_risk": 67544, "rr": 2.25529, "se": 0.489016, "se_clustered": 0.319883, "se_greenland_robins": 0.489016, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 9.91654, "lo": 0.603454, "log_rr": 0.894559, "p": 0.210323, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 2.44626, "se": 0.714118, "se_clustered": 0.439526, "se_greenland_robins": 0.714118, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.792166, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 7.75274, "lo": 0.559883, "log_rr": 0.73401, "p": 0.273596, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.08342, "se": 0.670439, "se_clustered": 0.493906, "se_greenland_robins": 0.670439, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Bladder cancer": { "all": { "clustered_wider": true, "glp1_affected": 33, "glp1_at_risk": 93765, "hi": 1.06619, "lo": 0.421186, "log_rr": -0.400294, "p": 0.0911309, "placebo_affected": 46, "placebo_at_risk": 67544, "rr": 0.670123, "se": 0.236936, "se_clustered": 0.236936, "se_greenland_robins": 0.22697, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.14454, "lo": 0.279488, "log_rr": -0.569896, "p": 0.11306, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.565584, "se": 0.359649, "se_clustered": 0.249952, "se_greenland_robins": 0.359649, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 21, "glp1_at_risk": 46377, "hi": 1.48915, "lo": 0.382198, "log_rr": -0.281803, "p": 0.416661, "placebo_affected": 25, "placebo_at_risk": 32526, "rr": 0.754422, "se": 0.346951, "se_clustered": 0.346951, "se_greenland_robins": 0.293696, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Bladder neoplasm": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.31812, "lo": 0.258679, "log_rr": -0.537981, "p": 0.195299, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.583926, "se": 0.415409, "se_clustered": 0.356117, "se_greenland_robins": 0.415409, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 1.91599, "lo": 0.103166, "log_rr": -0.81059, "p": 0.276791, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.444596, "se": 0.745332, "se_clustered": 0.470332, "se_greenland_robins": 0.745332, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.823781, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.78995, "lo": 0.248967, "log_rr": -0.404124, "p": 0.421939, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.667561, "se": 0.503228, "se_clustered": 0.502398, "se_greenland_robins": 0.503228, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Bladder transitional cell carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 41, "glp1_at_risk": 93765, "hi": 1.26136, "lo": 0.541952, "log_rr": -0.190196, "p": 0.377475, "placebo_affected": 48, "placebo_at_risk": 67544, "rr": 0.826797, "se": 0.215505, "se_clustered": 0.1945, "se_greenland_robins": 0.215505, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 27, "glp1_at_risk": 47388, "hi": 1.41092, "lo": 0.504927, "log_rr": -0.169551, "p": 0.517767, "placebo_affected": 32, "placebo_at_risk": 35018, "rr": 0.844043, "se": 0.262142, "se_clustered": 0.262142, "se_greenland_robins": 0.26107, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.872335, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 1.67435, "lo": 0.374905, "log_rr": -0.232829, "p": 0.541949, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.792289, "se": 0.381769, "se_clustered": 0.324989, "se_greenland_robins": 0.381769, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Blood creatinine increased": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.23858, "lo": 0.567765, "log_rr": 0.304543, "p": 0.492953, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.35601, "se": 0.444187, "se_clustered": 0.391656, "se_greenland_robins": 0.444187, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 8.48696, "lo": 0.837849, "log_rr": 0.980807, "p": 0.0968235, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 2.66661, "se": 0.590686, "se_clustered": 0.430038, "se_greenland_robins": 0.590686, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.648843, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 1.93955, "lo": 0.0488532, "log_rr": -1.17824, "p": 0.209629, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.30782, "se": 0.939147, "se_clustered": 0.61744, "se_greenland_robins": 0.939147, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Blood glucose increased": { "all": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 1.37817, "lo": 0.380163, "log_rr": -0.323201, "p": 0.325261, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 0.723829, "se": 0.328555, "se_clustered": 0.276781, "se_greenland_robins": 0.328555, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 1.54194, "lo": 0.223998, "log_rr": -0.531537, "p": 0.280121, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.587701, "se": 0.492142, "se_clustered": 0.492142, "se_greenland_robins": 0.415951, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.823828, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 3.09406, "lo": 0.358494, "log_rr": 0.0518215, "p": 0.924912, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.05319, "se": 0.549839, "se_clustered": 0.199447, "se_greenland_robins": 0.549839, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Bowen's disease": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.19686, "lo": 0.432352, "log_rr": -0.0257442, "p": 0.950498, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.974584, "se": 0.414687, "se_clustered": 0.249842, "se_greenland_robins": 0.414687, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 2.16223, "lo": 0.302947, "log_rr": -0.211529, "p": 0.673097, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.809346, "se": 0.501371, "se_clustered": 0.24676, "se_greenland_robins": 0.501371, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.928658, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 6.53197, "lo": 0.331279, "log_rr": 0.385957, "p": 0.611849, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 1.47102, "se": 0.760602, "se_clustered": 0.517576, "se_greenland_robins": 0.760602, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Bradycardia": { "all": { "clustered_wider": false, "glp1_affected": 67, "glp1_at_risk": 93765, "hi": 1.40808, "lo": 0.71734, "log_rr": 0.0050115, "p": 0.976763, "placebo_affected": 65, "placebo_at_risk": 67544, "rr": 1.00502, "se": 0.172052, "se_clustered": 0.138539, "se_greenland_robins": 0.172052, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 1.38861, "lo": 0.539339, "log_rr": -0.144554, "p": 0.549063, "placebo_affected": 37, "placebo_at_risk": 35018, "rr": 0.865408, "se": 0.241259, "se_clustered": 0.124016, "se_greenland_robins": 0.241259, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.896571, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 46377, "hi": 1.91583, "lo": 0.727857, "log_rr": 0.16625, "p": 0.500712, "placebo_affected": 28, "placebo_at_risk": 32526, "rr": 1.18087, "se": 0.246892, "se_clustered": 0.218869, "se_greenland_robins": 0.246892, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Brain injury": { "all": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 7.4671, "lo": 0.654471, "log_rr": 0.793289, "p": 0.201477, "placebo_affected": 6, "placebo_at_risk": 67544, "rr": 2.21066, "se": 0.621041, "se_clustered": 0.621041, "se_greenland_robins": 0.473538, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 22.7234, "lo": 0.239719, "log_rr": 0.847553, "p": 0.465442, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 2.33393, "se": 1.16117, "se_clustered": 1.16117, "se_greenland_robins": 0.690141, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 8.23656, "lo": 0.535301, "log_rr": 0.741828, "p": 0.287418, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.09977, "se": 0.697337, "se_clustered": 0.697337, "se_greenland_robins": 0.650733, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Brain stem infarction": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.08069, "lo": 0.392489, "log_rr": -0.101273, "p": 0.811875, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.903686, "se": 0.425505, "se_clustered": 0.290382, "se_greenland_robins": 0.425505, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 1.59678, "lo": 0.230205, "log_rr": -0.500397, "p": 0.311166, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.60629, "se": 0.494084, "se_clustered": 0.222416, "se_greenland_robins": 0.494084, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.827638, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 40.8164, "lo": 0.426832, "log_rr": 1.42886, "p": 0.219382, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 4.17393, "se": 1.1634, "se_clustered": 0.957131, "se_greenland_robins": 1.1634, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Breast cancer": { "all": { "clustered_wider": false, "glp1_affected": 58, "glp1_at_risk": 93765, "hi": 1.76274, "lo": 0.768092, "log_rr": 0.151512, "p": 0.474642, "placebo_affected": 39, "placebo_at_risk": 67544, "rr": 1.16359, "se": 0.211921, "se_clustered": 0.163685, "se_greenland_robins": 0.211921, "strata_with_events": 31, "trials": 234, "trials_with_events": 30 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 47388, "hi": 2.12848, "lo": 0.619974, "log_rr": 0.138665, "p": 0.659454, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 1.14874, "se": 0.31467, "se_clustered": 0.23433, "se_greenland_robins": 0.31467, "strata_with_events": 14, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.919264, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 46377, "hi": 2.06328, "lo": 0.671108, "log_rr": 0.162735, "p": 0.570048, "placebo_affected": 20, "placebo_at_risk": 32526, "rr": 1.17673, "se": 0.286516, "se_clustered": 0.233985, "se_greenland_robins": 0.286516, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 } }, "Breast cancer female": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 2.47087, "lo": 0.601204, "log_rr": 0.197875, "p": 0.583149, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.21881, "se": 0.360566, "se_clustered": 0.117484, "se_greenland_robins": 0.360566, "strata_with_events": 2, "trials": 234, "trials_with_events": 2 }, "discovered": false, "discovery": { "glp1_affected": 1, "glp1_at_risk": 47388, "hi": null, "lo": null, "p": null, "placebo_affected": 0, "placebo_at_risk": 35018, "rr": null, "se": null, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 }, "discovery_q": null, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 2.34875, "lo": 0.560342, "log_rr": 0.137337, "p": 0.707172, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 1.14721, "se": 0.365591, "se_clustered": null, "se_greenland_robins": 0.365591, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 } }, "Breast cancer metastatic": { "all": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 2.30707, "lo": 0.364609, "log_rr": -0.0864772, "p": 0.854217, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.917156, "se": 0.470648, "se_clustered": 0.346679, "se_greenland_robins": 0.470648, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 8.0622, "lo": 0.417317, "log_rr": 0.606639, "p": 0.421931, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 1.83426, "se": 0.755395, "se_clustered": 0.66907, "se_greenland_robins": 0.755395, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.87836, "lo": 0.146177, "log_rr": -0.64627, "p": 0.321116, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.523996, "se": 0.651373, "se_clustered": 0.34916, "se_greenland_robins": 0.651373, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Bronchial carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.96787, "lo": 0.570622, "log_rr": 0.263408, "p": 0.531177, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.30136, "se": 0.420639, "se_clustered": 0.338097, "se_greenland_robins": 0.420639, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 5.97876, "lo": 0.512431, "log_rr": 0.559812, "p": 0.371749, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.75034, "se": 0.626747, "se_clustered": 0.293298, "se_greenland_robins": 0.626747, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.29985, "lo": 0.304126, "log_rr": 0.00178306, "p": 0.997661, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.00178, "se": 0.608223, "se_clustered": 0.608223, "se_greenland_robins": 0.577363, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Bronchitis": { "all": { "clustered_wider": false, "glp1_affected": 72, "glp1_at_risk": 93765, "hi": 0.83423, "lo": 0.464092, "log_rr": -0.474459, "p": 0.00151661, "placebo_affected": 108, "placebo_at_risk": 67544, "rr": 0.622221, "se": 0.149601, "se_clustered": 0.126794, "se_greenland_robins": 0.149601, "strata_with_events": 25, "trials": 234, "trials_with_events": 25 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 36, "glp1_at_risk": 47388, "hi": 0.847156, "lo": 0.377443, "log_rr": -0.570102, "p": 0.0057062, "placebo_affected": 61, "placebo_at_risk": 35018, "rr": 0.565467, "se": 0.206245, "se_clustered": 0.140066, "se_greenland_robins": 0.206245, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.24548, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 36, "glp1_at_risk": 46377, "hi": 1.0642, "lo": 0.452993, "log_rr": -0.364826, "p": 0.0940575, "placebo_affected": 47, "placebo_at_risk": 32526, "rr": 0.694317, "se": 0.217888, "se_clustered": 0.199065, "se_greenland_robins": 0.217888, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Bronchitis chronic": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 2.35421, "lo": 0.397873, "log_rr": -0.0327087, "p": 0.942507, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.96782, "se": 0.453536, "se_clustered": 0.332044, "se_greenland_robins": 0.453536, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 2.97927, "lo": 0.214888, "log_rr": -0.222979, "p": 0.739565, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 0.800132, "se": 0.670756, "se_clustered": 0.424163, "se_greenland_robins": 0.670756, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.82735, "lo": 0.336983, "log_rr": 0.127225, "p": 0.837384, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.13567, "se": 0.619883, "se_clustered": 0.567467, "se_greenland_robins": 0.619883, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Bronchopneumonia": { "all": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 1.91742, "lo": 0.375842, "log_rr": -0.163802, "p": 0.693561, "placebo_affected": 22, "placebo_at_risk": 67544, "rr": 0.84891, "se": 0.415713, "se_clustered": 0.415713, "se_greenland_robins": 0.315198, "strata_with_events": 4, "trials": 234, "trials_with_events": 4 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 2.07035, "lo": 0.342182, "log_rr": -0.172349, "p": 0.707435, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.841686, "se": 0.459225, "se_clustered": 0.459225, "se_greenland_robins": 0.323395, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 15.9838, "lo": 0.0626394, "log_rr": 0.000606612, "p": 0.999658, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 1.00061, "se": 1.41378, "se_clustered": null, "se_greenland_robins": 1.41378, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 } }, "Bundle branch block left": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.42523, "lo": 0.29242, "log_rr": -0.437615, "p": 0.278792, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.645574, "se": 0.404063, "se_clustered": 0.369312, "se_greenland_robins": 0.404063, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 2.16229, "lo": 0.202652, "log_rr": -0.412547, "p": 0.494554, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.661962, "se": 0.603948, "se_clustered": 0.603948, "se_greenland_robins": 0.564509, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.861582, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 1.95571, "lo": 0.202418, "log_rr": -0.463333, "p": 0.423279, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.629183, "se": 0.578627, "se_clustered": 0.518361, "se_greenland_robins": 0.578627, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Bursitis": { "all": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 2.62024, "lo": 0.461997, "log_rr": 0.0955342, "p": 0.829155, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.10025, "se": 0.442728, "se_clustered": 0.442728, "se_greenland_robins": 0.395313, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 5.31118, "lo": 0.552666, "log_rr": 0.538407, "p": 0.350978, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 1.71327, "se": 0.577259, "se_clustered": 0.37433, "se_greenland_robins": 0.577259, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 3.451, "lo": 0.134922, "log_rr": -0.382199, "p": 0.643967, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.682359, "se": 0.826986, "se_clustered": 0.826986, "se_greenland_robins": 0.569042, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "COVID-19": { "all": { "clustered_wider": false, "glp1_affected": 329, "glp1_at_risk": 93765, "hi": 0.972283, "lo": 0.725155, "log_rr": -0.174739, "p": 0.019508, "placebo_affected": 375, "placebo_at_risk": 67544, "rr": 0.839676, "se": 0.074813, "se_clustered": 0.0374768, "se_greenland_robins": 0.074813, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 259, "glp1_at_risk": 47388, "hi": 1.01644, "lo": 0.729308, "log_rr": -0.149676, "p": 0.0771584, "placebo_affected": 291, "placebo_at_risk": 35018, "rr": 0.860987, "se": 0.0846864, "se_clustered": 0.0329721, "se_greenland_robins": 0.0846864, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 70, "glp1_at_risk": 46377, "hi": 1.04952, "lo": 0.560866, "log_rr": -0.26497, "p": 0.0973986, "placebo_affected": 84, "placebo_at_risk": 32526, "rr": 0.767229, "se": 0.159852, "se_clustered": 0.0417783, "se_greenland_robins": 0.159852, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "COVID-19 pneumonia": { "all": { "clustered_wider": false, "glp1_affected": 370, "glp1_at_risk": 93765, "hi": 0.917578, "lo": 0.695281, "log_rr": -0.224728, "p": 0.00149637, "placebo_affected": 433, "placebo_at_risk": 67544, "rr": 0.798733, "se": 0.070772, "se_clustered": 0.0291874, "se_greenland_robins": 0.070772, "strata_with_events": 23, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 276, "glp1_at_risk": 47388, "hi": 0.905443, "lo": 0.660193, "log_rr": -0.257276, "p": 0.00141016, "placebo_affected": 342, "placebo_at_risk": 35018, "rr": 0.773154, "se": 0.0805862, "se_clustered": 0.0258504, "se_greenland_robins": 0.0805862, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.143023, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 94, "glp1_at_risk": 46377, "hi": 1.19389, "lo": 0.667669, "log_rr": -0.113374, "p": 0.444459, "placebo_affected": 91, "placebo_at_risk": 32526, "rr": 0.892817, "se": 0.148262, "se_clustered": 0.0985256, "se_greenland_robins": 0.148262, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Calculus bladder": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.69614, "lo": 0.660732, "log_rr": 0.44644, "p": 0.309416, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.56274, "se": 0.439216, "se_clustered": 0.401908, "se_greenland_robins": 0.439216, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 5.82955, "lo": 0.586609, "log_rr": 0.614771, "p": 0.293977, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.84923, "se": 0.585811, "se_clustered": 0.498189, "se_greenland_robins": 0.585811, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.824414, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 8.87908, "lo": 0.176632, "log_rr": 0.225005, "p": 0.821861, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.25233, "se": 0.999351, "se_clustered": 0.999351, "se_greenland_robins": 0.670887, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Calculus ureteric": { "all": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 1.69531, "lo": 0.514863, "log_rr": -0.0679938, "p": 0.823028, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 0.934266, "se": 0.304016, "se_clustered": 0.263963, "se_greenland_robins": 0.304016, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.96967, "lo": 0.425008, "log_rr": -0.0888898, "p": 0.820255, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.914946, "se": 0.39121, "se_clustered": 0.271138, "se_greenland_robins": 0.39121, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.942654, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 3.12543, "lo": 0.300232, "log_rr": -0.031814, "p": 0.957548, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.968687, "se": 0.597657, "se_clustered": 0.597657, "se_greenland_robins": 0.480503, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Calculus urinary": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 1.75897, "lo": 0.550676, "log_rr": -0.0159387, "p": 0.957096, "placebo_affected": 22, "placebo_at_risk": 67544, "rr": 0.984188, "se": 0.296265, "se_clustered": 0.247602, "se_greenland_robins": 0.296265, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.62605, "lo": 0.564951, "log_rr": 0.197231, "p": 0.614838, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.21803, "se": 0.39197, "se_clustered": 0.240199, "se_greenland_robins": 0.39197, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.83938, "lo": 0.303228, "log_rr": -0.291921, "p": 0.525575, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 0.746828, "se": 0.459881, "se_clustered": 0.362239, "se_greenland_robins": 0.459881, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Cardiac arrest": { "all": { "clustered_wider": false, "glp1_affected": 136, "glp1_at_risk": 93765, "hi": 1.15492, "lo": 0.722897, "log_rr": -0.0902304, "p": 0.450291, "placebo_affected": 142, "placebo_at_risk": 67544, "rr": 0.913721, "se": 0.119522, "se_clustered": 0.113673, "se_greenland_robins": 0.119522, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 93, "glp1_at_risk": 47388, "hi": 1.23518, "lo": 0.679509, "log_rr": -0.0875824, "p": 0.565638, "placebo_affected": 99, "placebo_at_risk": 35018, "rr": 0.916143, "se": 0.152453, "se_clustered": 0.152453, "se_greenland_robins": 0.143813, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 43, "glp1_at_risk": 46377, "hi": 1.38407, "lo": 0.596063, "log_rr": -0.0961893, "p": 0.654459, "placebo_affected": 43, "placebo_at_risk": 32526, "rr": 0.908292, "se": 0.214912, "se_clustered": 0.16122, "se_greenland_robins": 0.214912, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Cardiac failure": { "all": { "clustered_wider": false, "glp1_affected": 502, "glp1_at_risk": 93765, "hi": 0.89988, "lo": 0.712244, "log_rr": -0.222415, "p": 0.000192714, "placebo_affected": 609, "placebo_at_risk": 67544, "rr": 0.800583, "se": 0.0596545, "se_clustered": 0.05432, "se_greenland_robins": 0.0596545, "strata_with_events": 30, "trials": 234, "trials_with_events": 30 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 330, "glp1_at_risk": 47388, "hi": 0.924315, "lo": 0.693853, "log_rr": -0.222099, "p": 0.00239991, "placebo_affected": 409, "placebo_at_risk": 35018, "rr": 0.800836, "se": 0.0731627, "se_clustered": 0.0590253, "se_greenland_robins": 0.0731627, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.157651, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 172, "glp1_at_risk": 46377, "hi": 1.00466, "lo": 0.63716, "log_rr": -0.223045, "p": 0.05486, "placebo_affected": 200, "placebo_at_risk": 32526, "rr": 0.800079, "se": 0.11617, "se_clustered": 0.11617, "se_greenland_robins": 0.103038, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Cardiac failure acute": { "all": { "clustered_wider": false, "glp1_affected": 119, "glp1_at_risk": 93765, "hi": 0.998218, "lo": 0.618842, "log_rr": -0.240845, "p": 0.048315, "placebo_affected": 148, "placebo_at_risk": 67544, "rr": 0.785964, "se": 0.121972, "se_clustered": 0.0721284, "se_greenland_robins": 0.121972, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 81, "glp1_at_risk": 47388, "hi": 1.03852, "lo": 0.581239, "log_rr": -0.252397, "p": 0.0882574, "placebo_affected": 103, "placebo_at_risk": 35018, "rr": 0.776937, "se": 0.148063, "se_clustered": 0.0405371, "se_greenland_robins": 0.148063, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.628862, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 46377, "hi": 1.22863, "lo": 0.528691, "log_rr": -0.215727, "p": 0.315943, "placebo_affected": 45, "placebo_at_risk": 32526, "rr": 0.805955, "se": 0.215118, "se_clustered": 0.20575, "se_greenland_robins": 0.215118, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Cardiac failure chronic": { "all": { "clustered_wider": false, "glp1_affected": 150, "glp1_at_risk": 93765, "hi": 1.24898, "lo": 0.788084, "log_rr": -0.00791167, "p": 0.946303, "placebo_affected": 145, "placebo_at_risk": 67544, "rr": 0.99212, "se": 0.117471, "se_clustered": 0.0742517, "se_greenland_robins": 0.117471, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 94, "glp1_at_risk": 47388, "hi": 1.30358, "lo": 0.736492, "log_rr": -0.0203707, "p": 0.888777, "placebo_affected": 95, "placebo_at_risk": 35018, "rr": 0.979835, "se": 0.145659, "se_clustered": 0.0772653, "se_greenland_robins": 0.145659, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.973628, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 56, "glp1_at_risk": 46377, "hi": 1.49851, "lo": 0.687708, "log_rr": 0.0150395, "p": 0.939664, "placebo_affected": 50, "placebo_at_risk": 32526, "rr": 1.01515, "se": 0.198692, "se_clustered": 0.16929, "se_greenland_robins": 0.198692, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Cardiac failure congestive": { "all": { "clustered_wider": false, "glp1_affected": 363, "glp1_at_risk": 93765, "hi": 1.00721, "lo": 0.759112, "log_rr": -0.134211, "p": 0.0628291, "placebo_affected": 400, "placebo_at_risk": 67544, "rr": 0.874405, "se": 0.0721412, "se_clustered": 0.0697314, "se_greenland_robins": 0.0721412, "strata_with_events": 32, "trials": 234, "trials_with_events": 32 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 237, "glp1_at_risk": 47388, "hi": 1.09664, "lo": 0.771918, "log_rr": -0.083314, "p": 0.352316, "placebo_affected": 253, "placebo_at_risk": 35018, "rr": 0.920062, "se": 0.0895747, "se_clustered": 0.0737404, "se_greenland_robins": 0.0895747, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 126, "glp1_at_risk": 46377, "hi": 1.01161, "lo": 0.627314, "log_rr": -0.227382, "p": 0.062145, "placebo_affected": 147, "placebo_at_risk": 32526, "rr": 0.796617, "se": 0.121903, "se_clustered": 0.102674, "se_greenland_robins": 0.121903, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 } }, "Cardio-respiratory arrest": { "all": { "clustered_wider": false, "glp1_affected": 69, "glp1_at_risk": 93765, "hi": 1.43268, "lo": 0.729363, "log_rr": 0.0219806, "p": 0.898447, "placebo_affected": 65, "placebo_at_risk": 67544, "rr": 1.02222, "se": 0.17223, "se_clustered": 0.118686, "se_greenland_robins": 0.17223, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 53, "glp1_at_risk": 47388, "hi": 1.67121, "lo": 0.757554, "log_rr": 0.117943, "p": 0.558997, "placebo_affected": 46, "placebo_at_risk": 35018, "rr": 1.12518, "se": 0.201842, "se_clustered": 0.113675, "se_greenland_robins": 0.201842, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 1.50497, "lo": 0.406055, "log_rr": -0.246247, "p": 0.461229, "placebo_affected": 19, "placebo_at_risk": 32526, "rr": 0.781729, "se": 0.3342, "se_clustered": 0.197007, "se_greenland_robins": 0.3342, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Cardiogenic shock": { "all": { "clustered_wider": true, "glp1_affected": 41, "glp1_at_risk": 93765, "hi": 1.0722, "lo": 0.445929, "log_rr": -0.368941, "p": 0.0992555, "placebo_affected": 58, "placebo_at_risk": 67544, "rr": 0.691466, "se": 0.223808, "se_clustered": 0.223808, "se_greenland_robins": 0.204642, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 47388, "hi": 0.85506, "lo": 0.292482, "log_rr": -0.692967, "p": 0.0113374, "placebo_affected": 40, "placebo_at_risk": 35018, "rr": 0.50009, "se": 0.27367, "se_clustered": 0.122238, "se_greenland_robins": 0.27367, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.319394, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 21, "glp1_at_risk": 46377, "hi": 2.23892, "lo": 0.549233, "log_rr": 0.103382, "p": 0.773051, "placebo_affected": 18, "placebo_at_risk": 32526, "rr": 1.10891, "se": 0.358483, "se_clustered": 0.358483, "se_greenland_robins": 0.321835, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Cardiomyopathy": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 1.00333, "lo": 0.23804, "log_rr": -0.715997, "p": 0.0510671, "placebo_affected": 22, "placebo_at_risk": 67544, "rr": 0.488705, "se": 0.367006, "se_clustered": 0.312165, "se_greenland_robins": 0.367006, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 1.21645, "lo": 0.169527, "log_rr": -0.789404, "p": 0.116362, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.454115, "se": 0.502732, "se_clustered": 0.491599, "se_greenland_robins": 0.502732, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.665905, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 1.53333, "lo": 0.186822, "log_rr": -0.625079, "p": 0.244426, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.535219, "se": 0.537011, "se_clustered": 0.396221, "se_greenland_robins": 0.537011, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Cardiopulmonary failure": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 1.46955, "lo": 0.369623, "log_rr": -0.305157, "p": 0.386126, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 0.737007, "se": 0.352106, "se_clustered": 0.200078, "se_greenland_robins": 0.352106, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.63105, "lo": 0.272661, "log_rr": -0.405152, "p": 0.374613, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.666876, "se": 0.456321, "se_clustered": 0.296331, "se_greenland_robins": 0.456321, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.54936, "lo": 0.288228, "log_rr": -0.15408, "p": 0.781722, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.857204, "se": 0.556093, "se_clustered": 0.283457, "se_greenland_robins": 0.556093, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Carotid artery occlusion": { "all": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 1.21541, "lo": 0.258104, "log_rr": -0.579653, "p": 0.142531, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 0.560092, "se": 0.395282, "se_clustered": 0.395282, "se_greenland_robins": 0.333755, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.3842, "lo": 0.160054, "log_rr": -0.753559, "p": 0.170932, "placebo_affected": 17, "placebo_at_risk": 35018, "rr": 0.470689, "se": 0.550359, "se_clustered": 0.550359, "se_greenland_robins": 0.428647, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.23282, "lo": 0.252001, "log_rr": -0.287529, "p": 0.605409, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.750115, "se": 0.556538, "se_clustered": 0.556538, "se_greenland_robins": 0.540033, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Carotid artery stenosis": { "all": { "clustered_wider": true, "glp1_affected": 126, "glp1_at_risk": 93765, "hi": 1.61644, "lo": 0.890785, "log_rr": 0.182287, "p": 0.230466, "placebo_affected": 99, "placebo_at_risk": 67544, "rr": 1.19996, "se": 0.152013, "se_clustered": 0.152013, "se_greenland_robins": 0.13477, "strata_with_events": 23, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 92, "glp1_at_risk": 47388, "hi": 1.73702, "lo": 0.902119, "log_rr": 0.22458, "p": 0.179058, "placebo_affected": 72, "placebo_at_risk": 35018, "rr": 1.2518, "se": 0.167141, "se_clustered": 0.167141, "se_greenland_robins": 0.155845, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 2.01909, "lo": 0.559583, "log_rr": 0.0610413, "p": 0.852078, "placebo_affected": 27, "placebo_at_risk": 32526, "rr": 1.06294, "se": 0.327355, "se_clustered": 0.327355, "se_greenland_robins": 0.268919, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Carotid endarterectomy": { "all": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 2.58587, "lo": 0.374728, "log_rr": -0.0157459, "p": 0.974509, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 0.984377, "se": 0.492768, "se_clustered": 0.492768, "se_greenland_robins": 0.317967, "strata_with_events": 3, "trials": 234, "trials_with_events": 3 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 47388, "hi": 2.70577, "lo": 0.681873, "log_rr": 0.306238, "p": 0.383781, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 1.35831, "se": 0.351613, "se_clustered": null, "se_greenland_robins": 0.351613, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 5.64378, "lo": 0.0022221, "log_rr": -2.18937, "p": 0.273654, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.111987, "se": 2.0, "se_clustered": 2.0, "se_greenland_robins": 1.30791, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Carpal tunnel syndrome": { "all": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 93765, "hi": 1.70517, "lo": 0.559663, "log_rr": -0.0233777, "p": 0.934444, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 0.976893, "se": 0.284211, "se_clustered": 0.256359, "se_greenland_robins": 0.284211, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 2.28084, "lo": 0.444005, "log_rr": 0.00631253, "p": 0.987936, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.00633, "se": 0.417473, "se_clustered": 0.252092, "se_greenland_robins": 0.417473, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 2.21085, "lo": 0.410603, "log_rr": -0.0483759, "p": 0.910316, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 0.952776, "se": 0.429473, "se_clustered": 0.429473, "se_greenland_robins": 0.388019, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Cataract": { "all": { "clustered_wider": false, "glp1_affected": 156, "glp1_at_risk": 93765, "hi": 1.04257, "lo": 0.676189, "log_rr": -0.174798, "p": 0.113526, "placebo_affected": 174, "placebo_at_risk": 67544, "rr": 0.839627, "se": 0.110454, "se_clustered": 0.100943, "se_greenland_robins": 0.110454, "strata_with_events": 32, "trials": 234, "trials_with_events": 32 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 95, "glp1_at_risk": 47388, "hi": 1.04548, "lo": 0.607329, "log_rr": -0.227104, "p": 0.101216, "placebo_affected": 115, "placebo_at_risk": 35018, "rr": 0.796838, "se": 0.138564, "se_clustered": 0.0621272, "se_greenland_robins": 0.138564, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 61, "glp1_at_risk": 46377, "hi": 1.50021, "lo": 0.565162, "log_rr": -0.0825184, "p": 0.740391, "placebo_affected": 59, "placebo_at_risk": 32526, "rr": 0.920795, "se": 0.249048, "se_clustered": 0.249048, "se_greenland_robins": 0.183229, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 } }, "Cataract operation": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.20132, "lo": 0.606091, "log_rr": 0.331418, "p": 0.43504, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.39294, "se": 0.424571, "se_clustered": 0.381752, "se_greenland_robins": 0.424571, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 4.91475, "lo": 0.579495, "log_rr": 0.523322, "p": 0.337277, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 1.68762, "se": 0.545377, "se_clustered": 0.545377, "se_greenland_robins": 0.537762, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 3.99527, "lo": 0.250306, "log_rr": 2.02605e-05, "p": 0.999977, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.00002, "se": 0.706692, "se_clustered": 0.000586352, "se_greenland_robins": 0.706692, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Cellulitis": { "all": { "clustered_wider": true, "glp1_affected": 246, "glp1_at_risk": 93765, "hi": 0.820194, "lo": 0.571634, "log_rr": -0.378735, "p": 3.92196e-05, "placebo_affected": 326, "placebo_at_risk": 67544, "rr": 0.684727, "se": 0.0921042, "se_clustered": 0.0921042, "se_greenland_robins": 0.0852549, "strata_with_events": 51, "trials": 234, "trials_with_events": 51 }, "discovered": true, "discovery": { "clustered_wider": true, "glp1_affected": 142, "glp1_at_risk": 47388, "hi": 0.799129, "lo": 0.519175, "log_rr": -0.439874, "p": 6.38728e-05, "placebo_affected": 206, "placebo_at_risk": 35018, "rr": 0.644118, "se": 0.110023, "se_clustered": 0.110023, "se_greenland_robins": 0.109705, "strata_with_events": 25, "trials": 117, "trials_with_events": 25 }, "discovery_q": 0.0164792, "merged_rows": { "groups": 1, "participants": 1 }, "replicated": true, "replication": { "clustered_wider": false, "glp1_affected": 104, "glp1_at_risk": 46377, "hi": 0.98243, "lo": 0.577136, "log_rr": -0.283702, "p": 0.036565, "placebo_affected": 120, "placebo_at_risk": 32526, "rr": 0.752991, "se": 0.135704, "se_clustered": 0.134289, "se_greenland_robins": 0.135704, "strata_with_events": 26, "trials": 117, "trials_with_events": 26 } }, "Cerebral haemorrhage": { "all": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 93765, "hi": 1.3035, "lo": 0.469568, "log_rr": -0.245443, "p": 0.346023, "placebo_affected": 34, "placebo_at_risk": 67544, "rr": 0.782358, "se": 0.260463, "se_clustered": 0.199146, "se_greenland_robins": 0.260463, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 1.34581, "lo": 0.364453, "log_rr": -0.356181, "p": 0.285168, "placebo_affected": 22, "placebo_at_risk": 35018, "rr": 0.700346, "se": 0.333259, "se_clustered": 0.231748, "se_greenland_robins": 0.333259, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.823828, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.12521, "lo": 0.409384, "log_rr": -0.0696148, "p": 0.868402, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.932753, "se": 0.420154, "se_clustered": 0.409071, "se_greenland_robins": 0.420154, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Cerebral infarction": { "all": { "clustered_wider": false, "glp1_affected": 102, "glp1_at_risk": 93765, "hi": 1.27257, "lo": 0.730304, "log_rr": -0.0366298, "p": 0.795974, "placebo_affected": 97, "placebo_at_risk": 67544, "rr": 0.964033, "se": 0.141668, "se_clustered": 0.119498, "se_greenland_robins": 0.141668, "strata_with_events": 33, "trials": 234, "trials_with_events": 33 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 66, "glp1_at_risk": 47388, "hi": 1.08976, "lo": 0.569354, "log_rr": -0.238646, "p": 0.149602, "placebo_affected": 81, "placebo_at_risk": 35018, "rr": 0.787693, "se": 0.165619, "se_clustered": 0.0755194, "se_greenland_robins": 0.165619, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.708206, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 36, "glp1_at_risk": 46377, "hi": 3.10028, "lo": 0.995032, "log_rr": 0.563256, "p": 0.0520423, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 1.75638, "se": 0.289922, "se_clustered": 0.235623, "se_greenland_robins": 0.289922, "strata_with_events": 20, "trials": 117, "trials_with_events": 20 } }, "Cerebral ischaemia": { "all": { "clustered_wider": false, "glp1_affected": 26, "glp1_at_risk": 93765, "hi": 1.76212, "lo": 0.580883, "log_rr": 0.0116556, "p": 0.967159, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 1.01172, "se": 0.283098, "se_clustered": 0.173548, "se_greenland_robins": 0.283098, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 47388, "hi": 2.34757, "lo": 0.619088, "log_rr": 0.186936, "p": 0.58248, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 1.20555, "se": 0.340029, "se_clustered": 0.133464, "se_greenland_robins": 0.340029, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.909995, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 1.87317, "lo": 0.237574, "log_rr": -0.404822, "p": 0.442194, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.667096, "se": 0.526773, "se_clustered": 0.521595, "se_greenland_robins": 0.526773, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Cerebrovascular accident": { "all": { "clustered_wider": false, "glp1_affected": 182, "glp1_at_risk": 93765, "hi": 0.940859, "lo": 0.636031, "log_rr": -0.256735, "p": 0.0101617, "placebo_affected": 223, "placebo_at_risk": 67544, "rr": 0.773574, "se": 0.0998859, "se_clustered": 0.0446212, "se_greenland_robins": 0.0998859, "strata_with_events": 32, "trials": 234, "trials_with_events": 32 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 125, "glp1_at_risk": 47388, "hi": 0.947528, "lo": 0.595432, "log_rr": -0.286183, "p": 0.0157458, "placebo_affected": 161, "placebo_at_risk": 35018, "rr": 0.751125, "se": 0.118515, "se_clustered": 0.0410994, "se_greenland_robins": 0.118515, "strata_with_events": 18, "trials": 117, "trials_with_events": 18 }, "discovery_q": 0.335688, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 57, "glp1_at_risk": 46377, "hi": 1.19641, "lo": 0.577622, "log_rr": -0.184754, "p": 0.319939, "placebo_affected": 62, "placebo_at_risk": 32526, "rr": 0.831309, "se": 0.18576, "se_clustered": 0.12736, "se_greenland_robins": 0.18576, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Cervical spinal stenosis": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 1.90448, "lo": 0.524808, "log_rr": -0.000255634, "p": 0.99938, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 0.999744, "se": 0.328816, "se_clustered": 0.328816, "se_greenland_robins": 0.310791, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 1.53389, "lo": 0.305586, "log_rr": -0.37886, "p": 0.3573, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 0.684642, "se": 0.411571, "se_clustered": 0.244001, "se_greenland_robins": 0.411571, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 4.59639, "lo": 0.638558, "log_rr": 0.538364, "p": 0.284992, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.7132, "se": 0.503534, "se_clustered": 0.489642, "se_greenland_robins": 0.503534, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Cervical vertebral fracture": { "all": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 2.58423, "lo": 0.362199, "log_rr": -0.0330666, "p": 0.947406, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.967474, "se": 0.501282, "se_clustered": 0.501282, "se_greenland_robins": 0.453622, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 3.76769, "lo": 0.0957414, "log_rr": -0.509822, "p": 0.586331, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 0.600603, "se": 0.936896, "se_clustered": 0.936896, "se_greenland_robins": 0.730539, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.911286, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 4.30026, "lo": 0.413946, "log_rr": 0.288328, "p": 0.629197, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.33419, "se": 0.597128, "se_clustered": 0.57029, "se_greenland_robins": 0.597128, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Chest discomfort": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 1.24086, "lo": 0.359664, "log_rr": -0.403391, "p": 0.201646, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 0.668051, "se": 0.315921, "se_clustered": 0.198866, "se_greenland_robins": 0.315921, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.27684, "lo": 0.302145, "log_rr": -0.476229, "p": 0.195229, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 0.621121, "se": 0.36767, "se_clustered": 0.23848, "se_greenland_robins": 0.36767, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.74621, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.77211, "lo": 0.242147, "log_rr": -0.199299, "p": 0.748615, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.819305, "se": 0.621904, "se_clustered": 0.405149, "se_greenland_robins": 0.621904, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Chest pain": { "all": { "clustered_wider": false, "glp1_affected": 184, "glp1_at_risk": 93765, "hi": 1.14157, "lo": 0.756533, "log_rr": -0.073304, "p": 0.484899, "placebo_affected": 182, "placebo_at_risk": 67544, "rr": 0.929318, "se": 0.104953, "se_clustered": 0.079841, "se_greenland_robins": 0.104953, "strata_with_events": 45, "trials": 234, "trials_with_events": 44 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 130, "glp1_at_risk": 47388, "hi": 1.15803, "lo": 0.718737, "log_rr": -0.0917702, "p": 0.450736, "placebo_affected": 135, "placebo_at_risk": 35018, "rr": 0.912315, "se": 0.121681, "se_clustered": 0.0878299, "se_greenland_robins": 0.121681, "strata_with_events": 22, "trials": 117, "trials_with_events": 21 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 54, "glp1_at_risk": 46377, "hi": 1.48115, "lo": 0.646356, "log_rr": -0.0217924, "p": 0.917949, "placebo_affected": 47, "placebo_at_risk": 32526, "rr": 0.978443, "se": 0.211541, "se_clustered": 0.211541, "se_greenland_robins": 0.207383, "strata_with_events": 23, "trials": 117, "trials_with_events": 23 } }, "Cholangiocarcinoma": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 2.03182, "lo": 0.634766, "log_rr": 0.127217, "p": 0.668194, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.13566, "se": 0.296799, "se_clustered": 0.196667, "se_greenland_robins": 0.296799, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 2.29065, "lo": 0.537974, "log_rr": 0.104446, "p": 0.777486, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.1101, "se": 0.369594, "se_clustered": 0.270495, "se_greenland_robins": 0.369594, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 3.14021, "lo": 0.445529, "log_rr": 0.167899, "p": 0.736092, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.18282, "se": 0.498168, "se_clustered": 0.320447, "se_greenland_robins": 0.498168, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Cholangitis": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 1.71802, "lo": 0.532818, "log_rr": -0.0441998, "p": 0.88235, "placebo_affected": 23, "placebo_at_risk": 67544, "rr": 0.956763, "se": 0.298666, "se_clustered": 0.298666, "se_greenland_robins": 0.298071, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 1.56344, "lo": 0.386998, "log_rr": -0.251223, "p": 0.480615, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.777849, "se": 0.356186, "se_clustered": 0.275709, "se_greenland_robins": 0.356186, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 6.81626, "lo": 0.375971, "log_rr": 0.470534, "p": 0.524414, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.60085, "se": 0.739186, "se_clustered": 0.739186, "se_greenland_robins": 0.569797, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Cholangitis acute": { "all": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 10.4311, "lo": 0.863894, "log_rr": 1.09924, "p": 0.0836765, "placebo_affected": 5, "placebo_at_risk": 67544, "rr": 3.00189, "se": 0.635495, "se_clustered": 0.635495, "se_greenland_robins": 0.522631, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 10.4983, "lo": 0.48323, "log_rr": 0.811975, "p": 0.301176, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 2.25235, "se": 0.78534, "se_clustered": 0.78534, "se_greenland_robins": 0.612155, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.82752, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 49.7822, "lo": 0.722975, "log_rr": 1.79164, "p": 0.0970138, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 5.99927, "se": 1.07962, "se_clustered": 1.00044, "se_greenland_robins": 1.07962, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Cholecystitis": { "all": { "clustered_wider": false, "glp1_affected": 140, "glp1_at_risk": 93765, "hi": 1.91889, "lo": 1.08904, "log_rr": 0.368525, "p": 0.0107641, "placebo_affected": 81, "placebo_at_risk": 67544, "rr": 1.4456, "se": 0.144505, "se_clustered": 0.138394, "se_greenland_robins": 0.144505, "strata_with_events": 43, "trials": 234, "trials_with_events": 42 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 77, "glp1_at_risk": 47388, "hi": 1.97056, "lo": 0.934937, "log_rr": 0.305521, "p": 0.108216, "placebo_affected": 49, "placebo_at_risk": 35018, "rr": 1.35733, "se": 0.190206, "se_clustered": 0.165877, "se_greenland_robins": 0.190206, "strata_with_events": 23, "trials": 117, "trials_with_events": 22 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 63, "glp1_at_risk": 46377, "hi": 2.43654, "lo": 1.01822, "log_rr": 0.454317, "p": 0.0412428, "placebo_affected": 32, "placebo_at_risk": 32526, "rr": 1.5751, "se": 0.222586, "se_clustered": 0.216437, "se_greenland_robins": 0.222586, "strata_with_events": 20, "trials": 117, "trials_with_events": 20 } }, "Cholecystitis acute": { "all": { "clustered_wider": true, "glp1_affected": 235, "glp1_at_risk": 93765, "hi": 1.7866, "lo": 1.0944, "log_rr": 0.335257, "p": 0.00733121, "placebo_affected": 143, "placebo_at_risk": 67544, "rr": 1.3983, "se": 0.12503, "se_clustered": 0.12503, "se_greenland_robins": 0.109533, "strata_with_events": 55, "trials": 234, "trials_with_events": 54 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 152, "glp1_at_risk": 47388, "hi": 1.9991, "lo": 1.06368, "log_rr": 0.377213, "p": 0.0191053, "placebo_affected": 92, "placebo_at_risk": 35018, "rr": 1.45821, "se": 0.160963, "se_clustered": 0.160963, "se_greenland_robins": 0.135001, "strata_with_events": 28, "trials": 117, "trials_with_events": 27 }, "discovery_q": 0.365123, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 83, "glp1_at_risk": 46377, "hi": 1.91045, "lo": 0.872352, "log_rr": 0.255388, "p": 0.201574, "placebo_affected": 51, "placebo_at_risk": 32526, "rr": 1.29096, "se": 0.199978, "se_clustered": 0.199978, "se_greenland_robins": 0.187594, "strata_with_events": 27, "trials": 117, "trials_with_events": 27 } }, "Cholecystitis chronic": { "all": { "clustered_wider": true, "glp1_affected": 44, "glp1_at_risk": 93765, "hi": 2.45294, "lo": 0.898115, "log_rr": 0.394916, "p": 0.123382, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 1.48426, "se": 0.256317, "se_clustered": 0.256317, "se_greenland_robins": 0.248615, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 30, "glp1_at_risk": 47388, "hi": 2.46565, "lo": 0.777128, "log_rr": 0.325153, "p": 0.269634, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 1.38424, "se": 0.294548, "se_clustered": 0.294548, "se_greenland_robins": 0.286071, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 5.11006, "lo": 0.637361, "log_rr": 0.590396, "p": 0.266234, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.8047, "se": 0.531038, "se_clustered": 0.531038, "se_greenland_robins": 0.504031, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Cholecystitis infective": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.55144, "lo": 0.561959, "log_rr": 0.345514, "p": 0.462576, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.41272, "se": 0.470335, "se_clustered": 0.291919, "se_greenland_robins": 0.470335, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 3.82907, "lo": 0.44, "log_rr": 0.260822, "p": 0.636537, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.298, "se": 0.55195, "se_clustered": 0.361612, "se_greenland_robins": 0.55195, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.917467, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 10.3703, "lo": 0.29771, "log_rr": 0.563657, "p": 0.533751, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 1.75709, "se": 0.905778, "se_clustered": 0.656436, "se_greenland_robins": 0.905778, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Cholelithiasis": { "all": { "clustered_wider": true, "glp1_affected": 359, "glp1_at_risk": 93765, "hi": 1.74446, "lo": 1.12215, "log_rr": 0.335846, "p": 0.00284609, "placebo_affected": 205, "placebo_at_risk": 67544, "rr": 1.39912, "se": 0.112553, "se_clustered": 0.112553, "se_greenland_robins": 0.0904156, "strata_with_events": 65, "trials": 234, "trials_with_events": 63 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 220, "glp1_at_risk": 47388, "hi": 1.84835, "lo": 1.17299, "log_rr": 0.386925, "p": 0.000851862, "placebo_affected": 121, "placebo_at_risk": 35018, "rr": 1.47245, "se": 0.116007, "se_clustered": 0.0985842, "se_greenland_robins": 0.116007, "strata_with_events": 32, "trials": 117, "trials_with_events": 31 }, "discovery_q": 0.10989, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 139, "glp1_at_risk": 46377, "hi": 1.98197, "lo": 0.842947, "log_rr": 0.256621, "p": 0.239351, "placebo_affected": 84, "placebo_at_risk": 32526, "rr": 1.29255, "se": 0.218102, "se_clustered": 0.218102, "se_greenland_robins": 0.144499, "strata_with_events": 33, "trials": 117, "trials_with_events": 32 } }, "Chronic gastritis": { "all": { "clustered_wider": true, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 2.29926, "lo": 0.544383, "log_rr": 0.112243, "p": 0.760064, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 1.11878, "se": 0.36753, "se_clustered": 0.36753, "se_greenland_robins": 0.315957, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 3.11785, "lo": 0.387974, "log_rr": 0.0951633, "p": 0.857936, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 1.09984, "se": 0.531633, "se_clustered": 0.531633, "se_greenland_robins": 0.403089, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.959593, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 3.13065, "lo": 0.422068, "log_rr": 0.139325, "p": 0.785198, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.1495, "se": 0.51119, "se_clustered": 0.51119, "se_greenland_robins": 0.50889, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Chronic kidney disease": { "all": { "clustered_wider": false, "glp1_affected": 179, "glp1_at_risk": 93765, "hi": 1.09409, "lo": 0.731042, "log_rr": -0.11168, "p": 0.277596, "placebo_affected": 198, "placebo_at_risk": 67544, "rr": 0.89433, "se": 0.102861, "se_clustered": 0.0874944, "se_greenland_robins": 0.102861, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 100, "glp1_at_risk": 47388, "hi": 1.13629, "lo": 0.666331, "log_rr": -0.139101, "p": 0.306968, "placebo_affected": 115, "placebo_at_risk": 35018, "rr": 0.87014, "se": 0.136159, "se_clustered": 0.118301, "se_greenland_robins": 0.136159, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.827638, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 79, "glp1_at_risk": 46377, "hi": 1.26205, "lo": 0.681933, "log_rr": -0.0750424, "p": 0.632741, "placebo_affected": 83, "placebo_at_risk": 32526, "rr": 0.927704, "se": 0.157034, "se_clustered": 0.134104, "se_greenland_robins": 0.157034, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Chronic lymphocytic leukaemia": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 2.92833, "lo": 0.660153, "log_rr": 0.329575, "p": 0.385822, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.39038, "se": 0.380037, "se_clustered": 0.315143, "se_greenland_robins": 0.380037, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 3.4722, "lo": 0.392205, "log_rr": 0.154409, "p": 0.781356, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.16697, "se": 0.556327, "se_clustered": 0.530027, "se_greenland_robins": 0.556327, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 4.50203, "lo": 0.578609, "log_rr": 0.4787, "p": 0.360395, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.61398, "se": 0.523391, "se_clustered": 0.415637, "se_greenland_robins": 0.523391, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Chronic obstructive pulmonary disease": { "all": { "clustered_wider": false, "glp1_affected": 248, "glp1_at_risk": 93765, "hi": 0.992882, "lo": 0.706378, "log_rr": -0.177374, "p": 0.0411303, "placebo_affected": 288, "placebo_at_risk": 67544, "rr": 0.837466, "se": 0.086854, "se_clustered": 0.0670785, "se_greenland_robins": 0.086854, "strata_with_events": 23, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 127, "glp1_at_risk": 47388, "hi": 1.00836, "lo": 0.633029, "log_rr": -0.224458, "p": 0.0587739, "placebo_affected": 157, "placebo_at_risk": 35018, "rr": 0.79895, "se": 0.118768, "se_clustered": 0.0907768, "se_greenland_robins": 0.118768, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 121, "glp1_at_risk": 46377, "hi": 1.13442, "lo": 0.688412, "log_rr": -0.123622, "p": 0.331967, "placebo_affected": 131, "placebo_at_risk": 32526, "rr": 0.883714, "se": 0.127424, "se_clustered": 0.0898651, "se_greenland_robins": 0.127424, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Circulatory collapse": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.8917, "lo": 0.526277, "log_rr": -0.00222663, "p": 0.994557, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 0.997776, "se": 0.326384, "se_clustered": 0.24472, "se_greenland_robins": 0.326384, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 2.72641, "lo": 0.499236, "log_rr": 0.154154, "p": 0.721882, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 1.16667, "se": 0.433084, "se_clustered": 0.358943, "se_greenland_robins": 0.433084, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 2.16381, "lo": 0.303289, "log_rr": -0.2106, "p": 0.674388, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.810098, "se": 0.501269, "se_clustered": 0.338238, "se_greenland_robins": 0.501269, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Clavicle fracture": { "all": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 1.48238, "lo": 0.156124, "log_rr": -0.731728, "p": 0.202528, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 0.481077, "se": 0.574183, "se_clustered": 0.574183, "se_greenland_robins": 0.403597, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.56199, "lo": 0.0831735, "log_rr": -0.77302, "p": 0.376669, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.461617, "se": 0.874407, "se_clustered": 0.874407, "se_greenland_robins": 0.526507, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.75399, "lo": 0.150544, "log_rr": -0.665803, "p": 0.287815, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.513861, "se": 0.626386, "se_clustered": 0.60034, "se_greenland_robins": 0.626386, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Clear cell renal cell carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 93765, "hi": 3.61048, "lo": 1.02301, "log_rr": 0.653295, "p": 0.0422883, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.92186, "se": 0.321714, "se_clustered": 0.152539, "se_greenland_robins": 0.321714, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 3.63287, "lo": 0.749882, "log_rr": 0.501092, "p": 0.213177, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 1.65052, "se": 0.402524, "se_clustered": 0.156199, "se_greenland_robins": 0.402524, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.797098, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 7.11227, "lo": 0.854115, "log_rr": 0.902065, "p": 0.0952513, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 2.46469, "se": 0.540701, "se_clustered": 0.322816, "se_greenland_robins": 0.540701, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Clostridium difficile colitis": { "all": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 3.62827, "lo": 0.903775, "log_rr": 0.593791, "p": 0.0940075, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.81084, "se": 0.354581, "se_clustered": 0.252427, "se_greenland_robins": 0.354581, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 3.68622, "lo": 0.65992, "log_rr": 0.444483, "p": 0.311132, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.55968, "se": 0.438845, "se_clustered": 0.239609, "se_greenland_robins": 0.438845, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.827638, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 7.67529, "lo": 0.70995, "log_rr": 0.847723, "p": 0.162747, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 2.33432, "se": 0.607298, "se_clustered": 0.577982, "se_greenland_robins": 0.607298, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Cognitive disorder": { "all": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 93765, "hi": 1.17333, "lo": 0.189009, "log_rr": -0.753058, "p": 0.105925, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 0.470924, "se": 0.465775, "se_clustered": 0.465775, "se_greenland_robins": 0.428679, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.86099, "lo": 0.111121, "log_rr": -0.788014, "p": 0.273053, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.454747, "se": 0.718953, "se_clustered": 0.718953, "se_greenland_robins": 0.53918, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.823781, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 2.00209, "lo": 0.125173, "log_rr": -0.691935, "p": 0.327884, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.500607, "se": 0.707221, "se_clustered": 0.608279, "se_greenland_robins": 0.707221, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Colitis": { "all": { "clustered_wider": true, "glp1_affected": 56, "glp1_at_risk": 93765, "hi": 2.17813, "lo": 0.907032, "log_rr": 0.340446, "p": 0.127672, "placebo_affected": 36, "placebo_at_risk": 67544, "rr": 1.40557, "se": 0.223485, "se_clustered": 0.223485, "se_greenland_robins": 0.21708, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 40, "glp1_at_risk": 47388, "hi": 3.41431, "lo": 1.13765, "log_rr": 0.678472, "p": 0.0155218, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 1.97086, "se": 0.280364, "se_clustered": 0.21045, "se_greenland_robins": 0.280364, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.335688, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 1.61616, "lo": 0.377319, "log_rr": -0.247305, "p": 0.505158, "placebo_affected": 17, "placebo_at_risk": 32526, "rr": 0.780903, "se": 0.371108, "se_clustered": 0.371108, "se_greenland_robins": 0.365517, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Colitis ischaemic": { "all": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 93765, "hi": 3.74412, "lo": 1.13388, "log_rr": 0.722916, "p": 0.017679, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 2.06043, "se": 0.304735, "se_clustered": 0.212162, "se_greenland_robins": 0.304735, "strata_with_events": 24, "trials": 234, "trials_with_events": 24 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 47388, "hi": 6.82754, "lo": 1.29798, "log_rr": 1.09089, "p": 0.0100014, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 2.97691, "se": 0.423517, "se_clustered": 0.268952, "se_greenland_robins": 0.423517, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.319394, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 3.18393, "lo": 0.52823, "log_rr": 0.259946, "p": 0.570545, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 1.29686, "se": 0.458258, "se_clustered": 0.246463, "se_greenland_robins": 0.458258, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Colon adenoma": { "all": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 1.52543, "lo": 0.540633, "log_rr": -0.0963698, "p": 0.715722, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 0.908128, "se": 0.26462, "se_clustered": 0.203827, "se_greenland_robins": 0.26462, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 1.64665, "lo": 0.419558, "log_rr": -0.184906, "p": 0.596036, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.831183, "se": 0.348806, "se_clustered": 0.146846, "se_greenland_robins": 0.348806, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.911436, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 2.69319, "lo": 0.390683, "log_rr": 0.0254345, "p": 0.958813, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.02576, "se": 0.492505, "se_clustered": 0.492505, "se_greenland_robins": 0.407451, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Colon cancer": { "all": { "clustered_wider": true, "glp1_affected": 57, "glp1_at_risk": 93765, "hi": 1.64835, "lo": 0.727962, "log_rr": 0.0911339, "p": 0.662034, "placebo_affected": 48, "placebo_at_risk": 67544, "rr": 1.09542, "se": 0.208493, "se_clustered": 0.208493, "se_greenland_robins": 0.19596, "strata_with_events": 22, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 24, "glp1_at_risk": 47388, "hi": 1.76898, "lo": 0.476833, "log_rr": -0.0850943, "p": 0.799158, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 0.918426, "se": 0.334442, "se_clustered": 0.334442, "se_greenland_robins": 0.294511, "strata_with_events": 11, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 33, "glp1_at_risk": 46377, "hi": 2.12494, "lo": 0.755005, "log_rr": 0.236355, "p": 0.370593, "placebo_affected": 24, "placebo_at_risk": 32526, "rr": 1.26662, "se": 0.263977, "se_clustered": 0.209403, "se_greenland_robins": 0.263977, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Colon cancer metastatic": { "all": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 3.46794, "lo": 0.539602, "log_rr": 0.313319, "p": 0.509161, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.36796, "se": 0.474622, "se_clustered": 0.474622, "se_greenland_robins": 0.417974, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 8.81508, "lo": 0.559903, "log_rr": 0.798236, "p": 0.256306, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 2.22162, "se": 0.70319, "se_clustered": 0.647713, "se_greenland_robins": 0.70319, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 4.64921, "lo": 0.215947, "log_rr": 0.00198694, "p": 0.997975, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.00199, "se": 0.78303, "se_clustered": 0.78303, "se_greenland_robins": 0.534183, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Colorectal adenoma": { "all": { "clustered_wider": false, "glp1_affected": 26, "glp1_at_risk": 93765, "hi": 7.0716, "lo": 1.43698, "log_rr": 1.15931, "p": 0.00434766, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 3.18774, "se": 0.406524, "se_clustered": 0.101058, "se_greenland_robins": 0.406524, "strata_with_events": 5, "trials": 234, "trials_with_events": 5 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 47388, "hi": 7.05541, "lo": 1.27635, "log_rr": 1.0989, "p": 0.0117563, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 3.00086, "se": 0.436179, "se_clustered": 0.0830554, "se_greenland_robins": 0.436179, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.319394, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 41.1748, "lo": 0.490855, "log_rr": 1.50311, "p": 0.183448, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 4.49565, "se": 1.12998, "se_clustered": 0.221509, "se_greenland_robins": 1.12998, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Completed suicide": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 4.44808, "lo": 0.550701, "log_rr": 0.447955, "p": 0.400597, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.56511, "se": 0.532927, "se_clustered": 0.532927, "se_greenland_robins": 0.455714, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 4.92814, "lo": 0.456727, "log_rr": 0.405646, "p": 0.503818, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.50027, "se": 0.606805, "se_clustered": 0.606805, "se_greenland_robins": 0.491406, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.866567, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 38.2702, "lo": 0.106968, "log_rr": 0.704725, "p": 0.638486, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 2.02329, "se": 1.5, "se_clustered": 1.5, "se_greenland_robins": 1.22951, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Concussion": { "all": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 1.40154, "lo": 0.432833, "log_rr": -0.249915, "p": 0.404416, "placebo_affected": 26, "placebo_at_risk": 67544, "rr": 0.778867, "se": 0.299745, "se_clustered": 0.25361, "se_greenland_robins": 0.299745, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.27745, "lo": 0.296046, "log_rr": -0.486187, "p": 0.192414, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 0.614967, "se": 0.372994, "se_clustered": 0.306695, "se_greenland_robins": 0.372994, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.740936, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 3.41324, "lo": 0.438845, "log_rr": 0.202027, "p": 0.699446, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.22388, "se": 0.523293, "se_clustered": 0.455834, "se_greenland_robins": 0.523293, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Confusional state": { "all": { "clustered_wider": true, "glp1_affected": 27, "glp1_at_risk": 93765, "hi": 1.95082, "lo": 0.415583, "log_rr": -0.104912, "p": 0.790276, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 0.900404, "se": 0.394477, "se_clustered": 0.394477, "se_greenland_robins": 0.265193, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 1.28435, "lo": 0.143045, "log_rr": -0.847174, "p": 0.130274, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.428625, "se": 0.559921, "se_clustered": 0.559921, "se_greenland_robins": 0.398359, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.69175, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 4.4544, "lo": 0.899576, "log_rr": 0.69403, "p": 0.0890114, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 2.00177, "se": 0.408101, "se_clustered": 0.351141, "se_greenland_robins": 0.408101, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Congestive cardiomyopathy": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 5.56417, "lo": 0.754552, "log_rr": 0.717358, "p": 0.159303, "placebo_affected": 6, "placebo_at_risk": 67544, "rr": 2.04901, "se": 0.509698, "se_clustered": 0.396253, "se_greenland_robins": 0.509698, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 5.57498, "lo": 0.220621, "log_rr": 0.10349, "p": 0.90004, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 1.10903, "se": 0.823892, "se_clustered": 0.597542, "se_greenland_robins": 0.823892, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.973628, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 11.3029, "lo": 0.790514, "log_rr": 1.09499, "p": 0.106622, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.98916, "se": 0.678616, "se_clustered": 0.29846, "se_greenland_robins": 0.678616, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Constipation": { "all": { "clustered_wider": false, "glp1_affected": 51, "glp1_at_risk": 93765, "hi": 1.71497, "lo": 0.754264, "log_rr": 0.128692, "p": 0.539121, "placebo_affected": 41, "placebo_at_risk": 67544, "rr": 1.13734, "se": 0.209547, "se_clustered": 0.13227, "se_greenland_robins": 0.209547, "strata_with_events": 22, "trials": 234, "trials_with_events": 22 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 33, "glp1_at_risk": 47388, "hi": 2.13675, "lo": 0.741427, "log_rr": 0.230055, "p": 0.394222, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 1.25867, "se": 0.270022, "se_clustered": 0.140071, "se_greenland_robins": 0.270022, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 1.86496, "lo": 0.503873, "log_rr": -0.0310949, "p": 0.925792, "placebo_affected": 17, "placebo_at_risk": 32526, "rr": 0.969384, "se": 0.333851, "se_clustered": 0.223359, "se_greenland_robins": 0.333851, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Contusion": { "all": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 93765, "hi": 1.63461, "lo": 0.554401, "log_rr": -0.0492312, "p": 0.858348, "placebo_affected": 27, "placebo_at_risk": 67544, "rr": 0.951961, "se": 0.27584, "se_clustered": 0.183363, "se_greenland_robins": 0.27584, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.74185, "lo": 0.379005, "log_rr": -0.207629, "p": 0.593588, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.812509, "se": 0.389077, "se_clustered": 0.164712, "se_greenland_robins": 0.389077, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.911436, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 2.42629, "lo": 0.518493, "log_rr": 0.114767, "p": 0.77065, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.12161, "se": 0.393679, "se_clustered": 0.312715, "se_greenland_robins": 0.393679, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Coronary angioplasty": { "all": { "clustered_wider": true, "glp1_affected": 101, "glp1_at_risk": 93765, "hi": 1.20257, "lo": 0.622038, "log_rr": -0.145148, "p": 0.388078, "placebo_affected": 115, "placebo_at_risk": 67544, "rr": 0.864894, "se": 0.168169, "se_clustered": 0.168169, "se_greenland_robins": 0.136017, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 96, "glp1_at_risk": 47388, "hi": 1.30924, "lo": 0.646699, "log_rr": -0.0832134, "p": 0.643744, "placebo_affected": 104, "placebo_at_risk": 35018, "rr": 0.920155, "se": 0.179932, "se_clustered": 0.179932, "se_greenland_robins": 0.141215, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 1.27126, "lo": 0.108592, "log_rr": -0.990072, "p": 0.114672, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 0.37155, "se": 0.627605, "se_clustered": 0.627605, "se_greenland_robins": 0.555235, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Coronary arterial stent insertion": { "all": { "clustered_wider": false, "glp1_affected": 381, "glp1_at_risk": 93765, "hi": 1.00897, "lo": 0.769014, "log_rr": -0.126858, "p": 0.0670886, "placebo_affected": 430, "placebo_at_risk": 67544, "rr": 0.880859, "se": 0.0692805, "se_clustered": 0.0378683, "se_greenland_robins": 0.0692805, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 356, "glp1_at_risk": 47388, "hi": 1.04391, "lo": 0.786725, "log_rr": -0.0984524, "p": 0.172433, "placebo_affected": 392, "placebo_at_risk": 35018, "rr": 0.906239, "se": 0.0721566, "se_clustered": 0.0382014, "se_greenland_robins": 0.0721566, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 46377, "hi": 1.02783, "lo": 0.383159, "log_rr": -0.465926, "p": 0.0641827, "placebo_affected": 38, "placebo_at_risk": 32526, "rr": 0.627554, "se": 0.251728, "se_clustered": 0.116335, "se_greenland_robins": 0.251728, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Coronary artery bypass": { "all": { "clustered_wider": false, "glp1_affected": 170, "glp1_at_risk": 93765, "hi": 0.975187, "lo": 0.653135, "log_rr": -0.225549, "p": 0.0274066, "placebo_affected": 210, "placebo_at_risk": 67544, "rr": 0.798078, "se": 0.102258, "se_clustered": 0.0594246, "se_greenland_robins": 0.102258, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 153, "glp1_at_risk": 47388, "hi": 1.03081, "lo": 0.67368, "log_rr": -0.182327, "p": 0.0928995, "placebo_affected": 183, "placebo_at_risk": 35018, "rr": 0.833329, "se": 0.108509, "se_clustered": 0.0317537, "se_greenland_robins": 0.108509, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.630739, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 1.0419, "lo": 0.308182, "log_rr": -0.568009, "p": 0.0675691, "placebo_affected": 27, "placebo_at_risk": 32526, "rr": 0.566652, "se": 0.310749, "se_clustered": 0.106747, "se_greenland_robins": 0.310749, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Coronary artery disease": { "all": { "clustered_wider": false, "glp1_affected": 468, "glp1_at_risk": 93765, "hi": 1.00472, "lo": 0.780264, "log_rr": -0.121707, "p": 0.0591684, "placebo_affected": 488, "placebo_at_risk": 67544, "rr": 0.885408, "se": 0.0644995, "se_clustered": 0.0580254, "se_greenland_robins": 0.0644995, "strata_with_events": 60, "trials": 234, "trials_with_events": 60 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 293, "glp1_at_risk": 47388, "hi": 0.979109, "lo": 0.716886, "log_rr": -0.176975, "p": 0.0260512, "placebo_affected": 337, "placebo_at_risk": 35018, "rr": 0.837801, "se": 0.0795234, "se_clustered": 0.0588198, "se_greenland_robins": 0.0795234, "strata_with_events": 29, "trials": 117, "trials_with_events": 29 }, "discovery_q": 0.414538, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 175, "glp1_at_risk": 46377, "hi": 1.22475, "lo": 0.794195, "log_rr": -0.0138435, "p": 0.900304, "placebo_affected": 151, "placebo_at_risk": 32526, "rr": 0.986252, "se": 0.110503, "se_clustered": 0.107121, "se_greenland_robins": 0.110503, "strata_with_events": 31, "trials": 117, "trials_with_events": 31 } }, "Coronary artery occlusion": { "all": { "clustered_wider": false, "glp1_affected": 51, "glp1_at_risk": 93765, "hi": 1.56549, "lo": 0.683441, "log_rr": 0.0337934, "p": 0.873017, "placebo_affected": 44, "placebo_at_risk": 67544, "rr": 1.03437, "se": 0.211437, "se_clustered": 0.159564, "se_greenland_robins": 0.211437, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 41, "glp1_at_risk": 47388, "hi": 1.68673, "lo": 0.675088, "log_rr": 0.0649412, "p": 0.781014, "placebo_affected": 36, "placebo_at_risk": 35018, "rr": 1.0671, "se": 0.233603, "se_clustered": 0.180963, "se_greenland_robins": 0.233603, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 2.38827, "lo": 0.338008, "log_rr": -0.107058, "p": 0.830054, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.898474, "se": 0.498798, "se_clustered": 0.323068, "se_greenland_robins": 0.498798, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Coronary artery restenosis": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 0.737979, "lo": 0.204189, "log_rr": -0.946274, "p": 0.0038902, "placebo_affected": 33, "placebo_at_risk": 67544, "rr": 0.388185, "se": 0.327778, "se_clustered": 0.327778, "se_greenland_robins": 0.323997, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 0.841979, "lo": 0.230817, "log_rr": -0.819064, "p": 0.0131031, "placebo_affected": 29, "placebo_at_risk": 35018, "rr": 0.440844, "se": 0.330141, "se_clustered": 0.330141, "se_greenland_robins": 0.329823, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.335688, "replicated": false, "replication": { "glp1_affected": 0, "glp1_at_risk": 46377, "hi": null, "lo": null, "p": null, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": null, "se": null, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Coronary artery stenosis": { "all": { "clustered_wider": false, "glp1_affected": 151, "glp1_at_risk": 93765, "hi": 1.06053, "lo": 0.683019, "log_rr": -0.161234, "p": 0.150879, "placebo_affected": 169, "placebo_at_risk": 67544, "rr": 0.851093, "se": 0.112246, "se_clustered": 0.0903784, "se_greenland_robins": 0.112246, "strata_with_events": 24, "trials": 234, "trials_with_events": 24 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 114, "glp1_at_risk": 47388, "hi": 1.02806, "lo": 0.62738, "log_rr": -0.219264, "p": 0.0818052, "placebo_affected": 140, "placebo_at_risk": 35018, "rr": 0.80311, "se": 0.125991, "se_clustered": 0.0976446, "se_greenland_robins": 0.125991, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.608586, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 46377, "hi": 1.74277, "lo": 0.656324, "log_rr": 0.0671866, "p": 0.787404, "placebo_affected": 29, "placebo_at_risk": 32526, "rr": 1.06949, "se": 0.249131, "se_clustered": 0.223086, "se_greenland_robins": 0.249131, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Coronary revascularisation": { "all": { "clustered_wider": false, "glp1_affected": 173, "glp1_at_risk": 93765, "hi": 1.04421, "lo": 0.696192, "log_rr": -0.159436, "p": 0.123152, "placebo_affected": 198, "placebo_at_risk": 67544, "rr": 0.852624, "se": 0.103417, "se_clustered": 0.071615, "se_greenland_robins": 0.103417, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 150, "glp1_at_risk": 47388, "hi": 1.05606, "lo": 0.684221, "log_rr": -0.162463, "p": 0.142291, "placebo_affected": 173, "placebo_at_risk": 35018, "rr": 0.850047, "se": 0.110722, "se_clustered": 0.0852202, "se_greenland_robins": 0.110722, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.700059, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 46377, "hi": 1.53507, "lo": 0.493427, "log_rr": -0.138902, "p": 0.631412, "placebo_affected": 25, "placebo_at_risk": 32526, "rr": 0.870314, "se": 0.289535, "se_clustered": 0.0725842, "se_greenland_robins": 0.289535, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Craniocerebral injury": { "all": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 93765, "hi": 2.12773, "lo": 0.681509, "log_rr": 0.185805, "p": 0.522344, "placebo_affected": 22, "placebo_at_risk": 67544, "rr": 1.20419, "se": 0.29044, "se_clustered": 0.285618, "se_greenland_robins": 0.29044, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.67645, "lo": 0.33569, "log_rr": -0.287445, "p": 0.483541, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 0.750178, "se": 0.410273, "se_clustered": 0.308446, "se_greenland_robins": 0.410273, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 4.8482, "lo": 0.824072, "log_rr": 0.692555, "p": 0.125536, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.99882, "se": 0.452076, "se_clustered": 0.452076, "se_greenland_robins": 0.436885, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Cystitis": { "all": { "clustered_wider": true, "glp1_affected": 36, "glp1_at_risk": 93765, "hi": 2.43213, "lo": 0.640484, "log_rr": 0.221619, "p": 0.514998, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 1.2481, "se": 0.340389, "se_clustered": 0.340389, "se_greenland_robins": 0.261745, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 47388, "hi": 6.41154, "lo": 0.76137, "log_rr": 0.792732, "p": 0.144732, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 2.20942, "se": 0.543565, "se_clustered": 0.543565, "se_greenland_robins": 0.384633, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.700059, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 1.49237, "lo": 0.313745, "log_rr": -0.379406, "p": 0.340264, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.684268, "se": 0.397849, "se_clustered": 0.397849, "se_greenland_robins": 0.387568, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Cystocele": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.82656, "lo": 0.51996, "log_rr": 0.192529, "p": 0.655772, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.21231, "se": 0.431912, "se_clustered": 0.398142, "se_greenland_robins": 0.431912, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 8.06848, "lo": 0.327965, "log_rr": 0.486558, "p": 0.55151, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.62671, "se": 0.817059, "se_clustered": 0.817059, "se_greenland_robins": 0.642789, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.897726, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.99371, "lo": 0.292537, "log_rr": -0.0663261, "p": 0.910988, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.935826, "se": 0.593296, "se_clustered": 0.333113, "se_greenland_robins": 0.593296, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Death": { "all": { "clustered_wider": false, "glp1_affected": 220, "glp1_at_risk": 93765, "hi": 1.12245, "lo": 0.773396, "log_rr": -0.0707236, "p": 0.456706, "placebo_affected": 227, "placebo_at_risk": 67544, "rr": 0.931719, "se": 0.0950227, "se_clustered": 0.0735464, "se_greenland_robins": 0.0950227, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 163, "glp1_at_risk": 47388, "hi": 1.20523, "lo": 0.781559, "log_rr": -0.0298988, "p": 0.786706, "placebo_affected": 165, "placebo_at_risk": 35018, "rr": 0.970544, "se": 0.110495, "se_clustered": 0.0818753, "se_greenland_robins": 0.110495, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 57, "glp1_at_risk": 46377, "hi": 1.19709, "lo": 0.576025, "log_rr": -0.185857, "p": 0.319265, "placebo_affected": 62, "placebo_at_risk": 32526, "rr": 0.830392, "se": 0.186609, "se_clustered": 0.100472, "se_greenland_robins": 0.186609, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Decreased appetite": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 4.75335, "lo": 0.859203, "log_rr": 0.70355, "p": 0.106914, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 2.02091, "se": 0.436386, "se_clustered": 0.278591, "se_greenland_robins": 0.436386, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 7.9711, "lo": 0.784465, "log_rr": 0.916534, "p": 0.121249, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 2.50061, "se": 0.591484, "se_clustered": 0.316446, "se_greenland_robins": 0.591484, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.665905, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 5.58198, "lo": 0.425517, "log_rr": 0.432547, "p": 0.510073, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.54118, "se": 0.656643, "se_clustered": 0.445211, "se_greenland_robins": 0.656643, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Decubitus ulcer": { "all": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.58236, "lo": 0.281269, "log_rr": -0.404763, "p": 0.358338, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.667135, "se": 0.440661, "se_clustered": 0.417542, "se_greenland_robins": 0.440661, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.44353, "lo": 0.136912, "log_rr": -0.810665, "p": 0.177314, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.444562, "se": 0.600905, "se_clustered": 0.600596, "se_greenland_robins": 0.600905, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 4.67919, "lo": 0.291525, "log_rr": 0.155247, "p": 0.826463, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.16795, "se": 0.708114, "se_clustered": 0.708114, "se_greenland_robins": 0.689761, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Deep vein thrombosis": { "all": { "clustered_wider": false, "glp1_affected": 103, "glp1_at_risk": 93765, "hi": 1.97499, "lo": 1.06038, "log_rr": 0.369598, "p": 0.0198322, "placebo_affected": 64, "placebo_at_risk": 67544, "rr": 1.44715, "se": 0.158659, "se_clustered": 0.139894, "se_greenland_robins": 0.158659, "strata_with_events": 28, "trials": 234, "trials_with_events": 28 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 59, "glp1_at_risk": 47388, "hi": 1.82711, "lo": 0.84333, "log_rr": 0.21617, "p": 0.273069, "placebo_affected": 44, "placebo_at_risk": 35018, "rr": 1.24131, "se": 0.197232, "se_clustered": 0.180906, "se_greenland_robins": 0.197232, "strata_with_events": 15, "trials": 117, "trials_with_events": 15 }, "discovery_q": 0.823781, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 44, "glp1_at_risk": 46377, "hi": 3.21861, "lo": 1.11423, "log_rr": 0.638557, "p": 0.0182911, "placebo_affected": 20, "placebo_at_risk": 32526, "rr": 1.89375, "se": 0.270613, "se_clustered": 0.231849, "se_greenland_robins": 0.270613, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Dehydration": { "all": { "clustered_wider": false, "glp1_affected": 160, "glp1_at_risk": 93765, "hi": 1.76321, "lo": 1.07218, "log_rr": 0.318417, "p": 0.0121012, "placebo_affected": 106, "placebo_at_risk": 67544, "rr": 1.37495, "se": 0.126901, "se_clustered": 0.0886117, "se_greenland_robins": 0.126901, "strata_with_events": 33, "trials": 234, "trials_with_events": 33 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 84, "glp1_at_risk": 47388, "hi": 2.06366, "lo": 1.03606, "log_rr": 0.379952, "p": 0.0306591, "placebo_affected": 55, "placebo_at_risk": 35018, "rr": 1.46221, "se": 0.175784, "se_clustered": 0.0541403, "se_greenland_robins": 0.175784, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.42757, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 76, "glp1_at_risk": 46377, "hi": 1.8429, "lo": 0.895509, "log_rr": 0.250489, "p": 0.173663, "placebo_affected": 51, "placebo_at_risk": 32526, "rr": 1.28465, "se": 0.184112, "se_clustered": 0.184112, "se_greenland_robins": 0.183581, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 } }, "Delirium": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 1.29677, "lo": 0.421143, "log_rr": -0.302453, "p": 0.291801, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 0.739003, "se": 0.286908, "se_clustered": 0.286908, "se_greenland_robins": 0.282472, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.03343, "lo": 0.107553, "log_rr": -1.09845, "p": 0.0570402, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.333389, "se": 0.577217, "se_clustered": 0.144346, "se_greenland_robins": 0.577217, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 1.97318, "lo": 0.527131, "log_rr": 0.019671, "p": 0.953416, "placebo_affected": 17, "placebo_at_risk": 32526, "rr": 1.01987, "se": 0.336729, "se_clustered": 0.18553, "se_greenland_robins": 0.336729, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Dementia": { "all": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 2.2099, "lo": 0.246052, "log_rr": -0.304633, "p": 0.586449, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 0.737394, "se": 0.56, "se_clustered": 0.56, "se_greenland_robins": 0.352131, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.61193, "lo": 0.0689882, "log_rr": -1.09819, "p": 0.171916, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.333473, "se": 0.803905, "se_clustered": 0.803905, "se_greenland_robins": 0.577156, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 5.60299, "lo": 0.365065, "log_rr": 0.357811, "p": 0.607541, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.4302, "se": 0.696691, "se_clustered": 0.696691, "se_greenland_robins": 0.492771, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Dengue fever": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 2.28725, "lo": 0.461254, "log_rr": 0.0267713, "p": 0.947743, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.02713, "se": 0.408465, "se_clustered": 0.408465, "se_greenland_robins": 0.368605, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 2.41855, "lo": 0.303391, "log_rr": -0.154783, "p": 0.770075, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.856601, "se": 0.529576, "se_clustered": 0.529576, "se_greenland_robins": 0.469879, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 5.73108, "lo": 0.325979, "log_rr": 0.312491, "p": 0.669175, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.36683, "se": 0.731347, "se_clustered": 0.731347, "se_greenland_robins": 0.604129, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Depression": { "all": { "clustered_wider": false, "glp1_affected": 56, "glp1_at_risk": 93765, "hi": 1.13238, "lo": 0.555661, "log_rr": -0.231636, "p": 0.202162, "placebo_affected": 64, "placebo_at_risk": 67544, "rr": 0.793235, "se": 0.181616, "se_clustered": 0.178099, "se_greenland_robins": 0.181616, "strata_with_events": 29, "trials": 234, "trials_with_events": 28 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 47388, "hi": 1.61077, "lo": 0.599786, "log_rr": -0.0172343, "p": 0.945479, "placebo_affected": 29, "placebo_at_risk": 35018, "rr": 0.982913, "se": 0.252019, "se_clustered": 0.184741, "se_greenland_robins": 0.252019, "strata_with_events": 12, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.999728, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 46377, "hi": 1.0634, "lo": 0.376094, "log_rr": -0.458224, "p": 0.0839629, "placebo_affected": 35, "placebo_at_risk": 32526, "rr": 0.632406, "se": 0.265154, "se_clustered": 0.200673, "se_greenland_robins": 0.265154, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 } }, "Device dislocation": { "all": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 1.12447, "lo": 0.246329, "log_rr": -0.641886, "p": 0.0974993, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 0.526299, "se": 0.387355, "se_clustered": 0.361194, "se_greenland_robins": 0.387355, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.33278, "lo": 0.216842, "log_rr": -0.620658, "p": 0.180302, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.537591, "se": 0.463237, "se_clustered": 0.161997, "se_greenland_robins": 0.463237, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 6.70226, "lo": 0.0374783, "log_rr": -0.690775, "p": 0.601608, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.501188, "se": 1.3231, "se_clustered": 1.3231, "se_greenland_robins": 0.706569, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Device malfunction": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 1.77582, "lo": 0.461064, "log_rr": -0.0999778, "p": 0.771336, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.904858, "se": 0.344006, "se_clustered": 0.290783, "se_greenland_robins": 0.344006, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 1.59544, "lo": 0.286092, "log_rr": -0.392147, "p": 0.371084, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.675605, "se": 0.438425, "se_clustered": 0.257332, "se_greenland_robins": 0.438425, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 5.05819, "lo": 0.445297, "log_rr": 0.405998, "p": 0.512516, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.5008, "se": 0.619915, "se_clustered": 0.619915, "se_greenland_robins": 0.582858, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Device related infection": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 1.24147, "lo": 0.358357, "log_rr": -0.404964, "p": 0.201395, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 0.667001, "se": 0.316976, "se_clustered": 0.299912, "se_greenland_robins": 0.316976, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.82292, "lo": 0.412752, "log_rr": -0.142235, "p": 0.707388, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.867418, "se": 0.378922, "se_clustered": 0.272259, "se_greenland_robins": 0.378922, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.75876, "lo": 0.0764848, "log_rr": -1.00303, "p": 0.209824, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.366768, "se": 0.79983, "se_clustered": 0.79983, "se_greenland_robins": 0.614948, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Diabetes mellitus": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 0.784658, "lo": 0.287138, "log_rr": -0.745151, "p": 0.00366574, "placebo_affected": 46, "placebo_at_risk": 67544, "rr": 0.474663, "se": 0.256455, "se_clustered": 0.226128, "se_greenland_robins": 0.256455, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 0.862037, "lo": 0.233232, "log_rr": -0.802089, "p": 0.0161669, "placebo_affected": 29, "placebo_at_risk": 35018, "rr": 0.448391, "se": 0.333492, "se_clustered": 0.250066, "se_greenland_robins": 0.333492, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.335688, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 1.29508, "lo": 0.206343, "log_rr": -0.659822, "p": 0.159089, "placebo_affected": 17, "placebo_at_risk": 32526, "rr": 0.516943, "se": 0.468576, "se_clustered": 0.468576, "se_greenland_robins": 0.401653, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Diabetes mellitus inadequate control": { "all": { "clustered_wider": false, "glp1_affected": 67, "glp1_at_risk": 93765, "hi": 0.773483, "lo": 0.421745, "log_rr": -0.560104, "p": 0.000294559, "placebo_affected": 113, "placebo_at_risk": 67544, "rr": 0.57115, "se": 0.154723, "se_clustered": 0.116589, "se_greenland_robins": 0.154723, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 46, "glp1_at_risk": 47388, "hi": 0.852735, "lo": 0.410165, "log_rr": -0.52525, "p": 0.00490522, "placebo_affected": 77, "placebo_at_risk": 35018, "rr": 0.591407, "se": 0.18671, "se_clustered": 0.123058, "se_greenland_robins": 0.18671, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.24548, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 46377, "hi": 0.910241, "lo": 0.307654, "log_rr": -0.636413, "p": 0.0214585, "placebo_affected": 36, "placebo_at_risk": 32526, "rr": 0.529187, "se": 0.276723, "se_clustered": 0.262156, "se_greenland_robins": 0.276723, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Diabetic foot": { "all": { "clustered_wider": false, "glp1_affected": 157, "glp1_at_risk": 93765, "hi": 0.98805, "lo": 0.647144, "log_rr": -0.223605, "p": 0.0383278, "placebo_affected": 187, "placebo_at_risk": 67544, "rr": 0.799631, "se": 0.107952, "se_clustered": 0.0542201, "se_greenland_robins": 0.107952, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 97, "glp1_at_risk": 47388, "hi": 1.06345, "lo": 0.624487, "log_rr": -0.204654, "p": 0.131816, "placebo_affected": 118, "placebo_at_risk": 35018, "rr": 0.814929, "se": 0.135804, "se_clustered": 0.0690871, "se_greenland_robins": 0.135804, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.69175, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 60, "glp1_at_risk": 46377, "hi": 1.09742, "lo": 0.546283, "log_rr": -0.255829, "p": 0.150551, "placebo_affected": 69, "placebo_at_risk": 32526, "rr": 0.774275, "se": 0.177957, "se_clustered": 0.0795442, "se_greenland_robins": 0.177957, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Diabetic foot infection": { "all": { "clustered_wider": false, "glp1_affected": 39, "glp1_at_risk": 93765, "hi": 1.34115, "lo": 0.555181, "log_rr": -0.147466, "p": 0.51221, "placebo_affected": 42, "placebo_at_risk": 67544, "rr": 0.862892, "se": 0.225001, "se_clustered": 0.185772, "se_greenland_robins": 0.225001, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 47388, "hi": 2.31138, "lo": 0.678764, "log_rr": 0.225181, "p": 0.471295, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 1.25255, "se": 0.312589, "se_clustered": 0.190937, "se_greenland_robins": 0.312589, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 1.10122, "lo": 0.293239, "log_rr": -0.565176, "p": 0.0940652, "placebo_affected": 24, "placebo_at_risk": 32526, "rr": 0.56826, "se": 0.337553, "se_clustered": 0.239818, "se_greenland_robins": 0.337553, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Diabetic gangrene": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 2.08485, "lo": 0.367044, "log_rr": -0.133789, "p": 0.762706, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.874775, "se": 0.443113, "se_clustered": 0.388743, "se_greenland_robins": 0.443113, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 6.97622, "lo": 0.398474, "log_rr": 0.511197, "p": 0.483923, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 1.66729, "se": 0.730274, "se_clustered": 0.702123, "se_greenland_robins": 0.730274, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 1.79393, "lo": 0.177822, "log_rr": -0.571283, "p": 0.332619, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.5648, "se": 0.589649, "se_clustered": 0.329533, "se_greenland_robins": 0.589649, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Diabetic ketoacidosis": { "all": { "clustered_wider": true, "glp1_affected": 67, "glp1_at_risk": 93765, "hi": 1.80935, "lo": 0.788959, "log_rr": 0.177964, "p": 0.40064, "placebo_affected": 47, "placebo_at_risk": 67544, "rr": 1.19478, "se": 0.211741, "se_clustered": 0.211741, "se_greenland_robins": 0.197415, "strata_with_events": 23, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 34, "glp1_at_risk": 47388, "hi": 2.35686, "lo": 0.574002, "log_rr": 0.151104, "p": 0.674958, "placebo_affected": 25, "placebo_at_risk": 35018, "rr": 1.16312, "se": 0.360326, "se_clustered": 0.360326, "se_greenland_robins": 0.278538, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.928742, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 33, "glp1_at_risk": 46377, "hi": 2.1263, "lo": 0.709991, "log_rr": 0.205941, "p": 0.461751, "placebo_affected": 22, "placebo_at_risk": 32526, "rr": 1.22868, "se": 0.279824, "se_clustered": 0.225296, "se_greenland_robins": 0.279824, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Diabetic metabolic decompensation": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 0.841397, "lo": 0.217268, "log_rr": -0.849657, "p": 0.0138958, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 0.427562, "se": 0.345397, "se_clustered": 0.297239, "se_greenland_robins": 0.345397, "strata_with_events": 10, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.51217, "lo": 0.184238, "log_rr": -0.638988, "p": 0.234093, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.527826, "se": 0.537019, "se_clustered": 0.523171, "se_greenland_robins": 0.537019, "strata_with_events": 5, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 0.904022, "lo": 0.152838, "log_rr": -0.989641, "p": 0.0290737, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.37171, "se": 0.453447, "se_clustered": 0.351149, "se_greenland_robins": 0.453447, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Diabetic nephropathy": { "all": { "clustered_wider": true, "glp1_affected": 26, "glp1_at_risk": 93765, "hi": 1.49975, "lo": 0.492523, "log_rr": -0.151459, "p": 0.593906, "placebo_affected": 28, "placebo_at_risk": 67544, "rr": 0.859453, "se": 0.284065, "se_clustered": 0.284065, "se_greenland_robins": 0.277601, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { 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"glp1_affected": 60, "glp1_at_risk": 93765, "hi": 1.91068, "lo": 0.652674, "log_rr": 0.110391, "p": 0.687052, "placebo_affected": 53, "placebo_at_risk": 67544, "rr": 1.11671, "se": 0.27402, "se_clustered": 0.27402, "se_greenland_robins": 0.189213, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 39, "glp1_at_risk": 47388, "hi": 2.86679, "lo": 0.543349, "log_rr": 0.221595, "p": 0.601484, "placebo_affected": 31, "placebo_at_risk": 35018, "rr": 1.24807, "se": 0.424293, "se_clustered": 0.424293, "se_greenland_robins": 0.241109, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 46377, "hi": 1.70159, "lo": 0.510172, "log_rr": -0.0707219, "p": 0.81798, "placebo_affected": 22, "placebo_at_risk": 32526, "rr": 0.931721, "se": 0.307294, "se_clustered": 0.26771, "se_greenland_robins": 0.307294, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Diarrhoea": { "all": { "clustered_wider": false, "glp1_affected": 110, "glp1_at_risk": 93765, "hi": 2.12992, "lo": 1.14759, "log_rr": 0.446875, "p": 0.00461749, "placebo_affected": 64, "placebo_at_risk": 67544, "rr": 1.56342, "se": 0.157763, "se_clustered": 0.118807, "se_greenland_robins": 0.157763, "strata_with_events": 26, "trials": 234, "trials_with_events": 25 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 65, "glp1_at_risk": 47388, "hi": 2.12482, "lo": 0.983151, "log_rr": 0.368348, "p": 0.0609949, "placebo_affected": 43, "placebo_at_risk": 35018, "rr": 1.44534, "se": 0.196606, "se_clustered": 0.130922, "se_greenland_robins": 0.196606, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 45, "glp1_at_risk": 46377, "hi": 3.01774, "lo": 1.06683, "log_rr": 0.584602, "p": 0.0275349, "placebo_affected": 21, "placebo_at_risk": 32526, "rr": 1.79428, "se": 0.265264, "se_clustered": 0.21736, "se_greenland_robins": 0.265264, "strata_with_events": 14, "trials": 117, "trials_with_events": 13 } }, "Diffuse large B-cell lymphoma": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 3.40588, "lo": 0.660935, "log_rr": 0.405702, "p": 0.332075, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.50036, "se": 0.418274, "se_clustered": 0.415197, "se_greenland_robins": 0.418274, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.64299, "lo": 0.344389, "log_rr": -0.0470353, "p": 0.927911, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.954054, "se": 0.51988, "se_clustered": 0.501854, "se_greenland_robins": 0.51988, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.989261, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 20.1614, "lo": 0.609607, "log_rr": 1.25441, "p": 0.159892, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 3.50578, "se": 0.892545, "se_clustered": 0.892545, "se_greenland_robins": 0.8015, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Diverticulitis": { "all": { "clustered_wider": true, "glp1_affected": 89, "glp1_at_risk": 93765, "hi": 1.36343, "lo": 0.658722, "log_rr": -0.0537247, "p": 0.772202, "placebo_affected": 80, "placebo_at_risk": 67544, "rr": 0.947693, "se": 0.18558, "se_clustered": 0.18558, "se_greenland_robins": 0.155878, "strata_with_events": 41, "trials": 234, "trials_with_events": 40 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 57, "glp1_at_risk": 47388, "hi": 1.5312, "lo": 0.578544, "log_rr": -0.0605946, "p": 0.807196, "placebo_affected": 54, "placebo_at_risk": 35018, "rr": 0.941205, "se": 0.248293, "se_clustered": 0.248293, "se_greenland_robins": 0.193008, "strata_with_events": 21, "trials": 117, "trials_with_events": 20 }, "discovery_q": 0.937672, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 46377, "hi": 1.61201, "lo": 0.572073, "log_rr": -0.0405025, "p": 0.878198, "placebo_affected": 26, "placebo_at_risk": 32526, "rr": 0.960307, "se": 0.264284, "se_clustered": 0.263779, "se_greenland_robins": 0.264284, "strata_with_events": 20, "trials": 117, "trials_with_events": 20 } }, "Diverticulum": { "all": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 1.49599, "lo": 0.350072, "log_rr": -0.323413, "p": 0.382736, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 0.723675, "se": 0.370519, "se_clustered": 0.370519, "se_greenland_robins": 0.328468, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 1.10634, "lo": 0.188652, "log_rr": -0.783398, "p": 0.0825602, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.456851, "se": 0.451261, "se_clustered": 0.366185, "se_greenland_robins": 0.451261, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.608586, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 3.78675, "lo": 0.495709, "log_rr": 0.314871, "p": 0.543826, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.37008, "se": 0.518702, "se_clustered": 0.405516, "se_greenland_robins": 0.518702, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Diverticulum intestinal": { "all": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 5.06926, "lo": 1.15116, "log_rr": 0.88198, "p": 0.0196908, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 2.41568, "se": 0.378177, "se_clustered": 0.252029, "se_greenland_robins": 0.378177, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 10.8636, "lo": 1.1519, "log_rr": 1.26342, "p": 0.0273145, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 3.53749, "se": 0.57246, "se_clustered": 0.0909872, "se_greenland_robins": 0.57246, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.414538, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 4.587, "lo": 0.606338, "log_rr": 0.511454, "p": 0.321799, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.66771, "se": 0.51622, "se_clustered": 0.444436, "se_greenland_robins": 0.51622, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Diverticulum intestinal haemorrhagic": { "all": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 93765, "hi": 0.854163, "lo": 0.127824, "log_rr": -1.10737, "p": 0.0222969, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.330427, "se": 0.484568, "se_clustered": 0.460916, "se_greenland_robins": 0.484568, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.3092, "lo": 0.145134, "log_rr": -0.830341, "p": 0.138922, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.4359, "se": 0.561111, "se_clustered": 0.542874, "se_greenland_robins": 0.561111, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.700059, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 1.24394, "lo": 0.0201455, "log_rr": -1.84324, "p": 0.0796997, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.158303, "se": 1.05182, "se_clustered": 1.05182, "se_greenland_robins": 1.04219, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Dizziness": { "all": { "clustered_wider": true, "glp1_affected": 70, "glp1_at_risk": 93765, "hi": 2.01556, "lo": 0.800416, "log_rr": 0.239138, "p": 0.310091, "placebo_affected": 51, "placebo_at_risk": 67544, "rr": 1.27015, "se": 0.235597, "se_clustered": 0.235597, "se_greenland_robins": 0.186532, "strata_with_events": 24, "trials": 234, "trials_with_events": 24 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 46, "glp1_at_risk": 47388, "hi": 2.44543, "lo": 0.790739, "log_rr": 0.329717, "p": 0.2523, "placebo_affected": 31, "placebo_at_risk": 35018, "rr": 1.39057, "se": 0.288018, "se_clustered": 0.288018, "se_greenland_robins": 0.23415, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 24, "glp1_at_risk": 46377, "hi": 2.5241, "lo": 0.465128, "log_rr": 0.0802196, "p": 0.852506, "placebo_affected": 20, "placebo_at_risk": 32526, "rr": 1.08353, "se": 0.431469, "se_clustered": 0.431469, "se_greenland_robins": 0.310121, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Drug hypersensitivity": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 2.77809, "lo": 0.632895, "log_rr": 0.282156, "p": 0.454632, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.32599, "se": 0.377357, "se_clustered": 0.3015, "se_greenland_robins": 0.377357, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 3.45609, "lo": 0.601295, "log_rr": 0.365734, "p": 0.412337, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.44157, "se": 0.446133, "se_clustered": 0.302197, "se_greenland_robins": 0.446133, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 4.60644, "lo": 0.255645, "log_rr": 0.0817444, "p": 0.911758, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.08518, "se": 0.737621, "se_clustered": 0.737621, "se_greenland_robins": 0.711764, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Drug-induced liver injury": { "all": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 2.37475, "lo": 0.39814, "log_rr": -0.0280309, "p": 0.950939, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.972358, "se": 0.455581, "se_clustered": 0.444695, "se_greenland_robins": 0.455581, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 2.68126, "lo": 0.221899, "log_rr": -0.259624, "p": 0.682966, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.771342, "se": 0.63568, "se_clustered": 0.63568, "se_greenland_robins": 0.578276, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 7.57868, "lo": 0.274187, "log_rr": 0.365697, "p": 0.665835, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 1.44152, "se": 0.846772, "se_clustered": 0.846772, "se_greenland_robins": 0.762522, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Dry gangrene": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.50069, "lo": 0.309867, "log_rr": -0.382844, "p": 0.341449, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.681919, "se": 0.402441, "se_clustered": 0.319956, "se_greenland_robins": 0.402441, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.41231, "lo": 0.317475, "log_rr": -0.133386, "p": 0.796538, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.875127, "se": 0.517342, "se_clustered": 0.295241, "se_greenland_robins": 0.517342, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 2.97234, "lo": 0.0681719, "log_rr": -0.798186, "p": 0.40721, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.450145, "se": 0.963047, "se_clustered": 0.963047, "se_greenland_robins": 0.662034, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Duodenal ulcer": { "all": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 93765, "hi": 1.37845, "lo": 0.495304, "log_rr": -0.190814, "p": 0.464917, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 0.826286, "se": 0.261112, "se_clustered": 0.218463, "se_greenland_robins": 0.261112, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 1.68519, "lo": 0.470719, "log_rr": -0.115808, "p": 0.721884, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.890646, "se": 0.325356, "se_clustered": 0.269535, "se_greenland_robins": 0.325356, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.71675, "lo": 0.307559, "log_rr": -0.319327, "p": 0.46664, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.726638, "se": 0.438662, "se_clustered": 0.336528, "se_greenland_robins": 0.438662, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Duodenal ulcer haemorrhage": { "all": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.59538, "lo": 0.475285, "log_rr": -0.138364, "p": 0.654232, "placebo_affected": 23, "placebo_at_risk": 67544, "rr": 0.870782, "se": 0.308922, "se_clustered": 0.308922, "se_greenland_robins": 0.305569, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.29509, "lo": 0.28918, "log_rr": -0.491062, "p": 0.199178, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.611976, "se": 0.382478, "se_clustered": 0.192415, "se_greenland_robins": 0.382478, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.755704, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 7.88688, "lo": 0.411902, "log_rr": 0.589115, "p": 0.434077, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.80239, "se": 0.753118, "se_clustered": 0.753118, "se_greenland_robins": 0.557486, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Duodenitis": { "all": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.39278, "lo": 0.250322, "log_rr": -0.526851, "p": 0.228864, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.590461, "se": 0.437842, "se_clustered": 0.437842, "se_greenland_robins": 0.387983, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 2.51869, "lo": 0.397092, "log_rr": 7.49958e-05, "p": 0.999873, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 1.00007, "se": 0.471265, "se_clustered": 0.351544, "se_greenland_robins": 0.471265, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 0.999113, "lo": 0.0159339, "log_rr": -2.0701, "p": 0.0499018, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.126173, "se": 1.05574, "se_clustered": 1.05574, "se_greenland_robins": 0.972028, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Dyspepsia": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 2.61948, "lo": 0.64334, "log_rr": 0.260948, "p": 0.46629, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.29816, "se": 0.358185, "se_clustered": 0.310627, "se_greenland_robins": 0.358185, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 3.38399, "lo": 0.570179, "log_rr": 0.328626, "p": 0.469464, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 1.38906, "se": 0.45431, "se_clustered": 0.45431, "se_greenland_robins": 0.439634, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.823, "lo": 0.336658, "log_rr": 0.126174, "p": 0.838698, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.13448, "se": 0.619839, "se_clustered": 0.345661, "se_greenland_robins": 0.619839, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Dysphagia": { "all": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 4.61145, "lo": 0.665207, "log_rr": 0.560442, "p": 0.256525, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.75145, "se": 0.493937, "se_clustered": 0.493937, "se_greenland_robins": 0.398151, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 5.27938, "lo": 0.27933, "log_rr": 0.194223, "p": 0.79561, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.21437, "se": 0.749802, "se_clustered": 0.749802, "se_greenland_robins": 0.514468, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 11.1021, "lo": 0.813797, "log_rr": 1.10054, "p": 0.0987621, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 3.0058, "se": 0.66664, "se_clustered": 0.60215, "se_greenland_robins": 0.66664, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Dyspnoea": { "all": { "clustered_wider": false, "glp1_affected": 128, "glp1_at_risk": 93765, "hi": 1.00819, "lo": 0.625868, "log_rr": -0.230228, "p": 0.0583742, "placebo_affected": 153, "placebo_at_risk": 67544, "rr": 0.794353, "se": 0.121629, "se_clustered": 0.113544, "se_greenland_robins": 0.121629, "strata_with_events": 23, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 70, "glp1_at_risk": 47388, "hi": 0.958774, "lo": 0.517681, "log_rr": -0.350248, "p": 0.0258982, "placebo_affected": 97, "placebo_at_risk": 35018, "rr": 0.704513, "se": 0.157222, "se_clustered": 0.128366, "se_greenland_robins": 0.157222, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.414538, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 58, "glp1_at_risk": 46377, "hi": 1.38868, "lo": 0.651068, "log_rr": -0.0503955, "p": 0.794254, "placebo_affected": 56, "placebo_at_risk": 32526, "rr": 0.950853, "se": 0.193241, "se_clustered": 0.171747, "se_greenland_robins": 0.193241, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Dyspnoea exertional": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 0.925632, "lo": 0.190237, "log_rr": -0.86838, "p": 0.0314428, "placebo_affected": 31, "placebo_at_risk": 67544, "rr": 0.419631, "se": 0.403631, "se_clustered": 0.403631, "se_greenland_robins": 0.330272, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.17286, "lo": 0.112835, "log_rr": -1.01119, "p": 0.0904543, "placebo_affected": 22, "placebo_at_risk": 35018, "rr": 0.363785, "se": 0.597276, "se_clustered": 0.597276, "se_greenland_robins": 0.412666, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.628862, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.27061, "lo": 0.136231, "log_rr": -0.586678, "p": 0.413697, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.556172, "se": 0.717731, "se_clustered": 0.717731, "se_greenland_robins": 0.557558, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Electrolyte imbalance": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.47533, "lo": 0.481959, "log_rr": 0.0882388, "p": 0.832584, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.09225, "se": 0.417424, "se_clustered": 0.378197, "se_greenland_robins": 0.417424, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 5.97596, "lo": 0.51254, "log_rr": 0.559684, "p": 0.371725, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.75012, "se": 0.626573, "se_clustered": 0.571481, "se_greenland_robins": 0.626573, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.25556, "lo": 0.227165, "log_rr": -0.33434, "p": 0.568037, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.71581, "se": 0.585592, "se_clustered": 0.54708, "se_greenland_robins": 0.585592, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Embolic stroke": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 4.17404, "lo": 0.410107, "log_rr": 0.268774, "p": 0.649768, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 1.30836, "se": 0.591904, "se_clustered": 0.591904, "se_greenland_robins": 0.368391, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 8.60846, "lo": 0.409095, "log_rr": 0.629469, "p": 0.417985, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.87661, "se": 0.777196, "se_clustered": 0.777196, "se_greenland_robins": 0.437828, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 2.06005, "lo": 0.0776674, "log_rr": -0.916295, "p": 0.273203, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.399998, "se": 0.836252, "se_clustered": 0.755356, "se_greenland_robins": 0.836252, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Encephalopathy": { "all": { "clustered_wider": false, "glp1_affected": 36, "glp1_at_risk": 93765, "hi": 2.09133, "lo": 0.765607, "log_rr": 0.235356, "p": 0.35857, "placebo_affected": 27, "placebo_at_risk": 67544, "rr": 1.26536, "se": 0.256353, "se_clustered": 0.180713, "se_greenland_robins": 0.256353, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 47388, "hi": 2.38156, "lo": 0.598305, "log_rr": 0.17705, "p": 0.615384, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 1.19369, "se": 0.352407, "se_clustered": 0.25416, "se_greenland_robins": 0.352407, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 2.81497, "lo": 0.649895, "log_rr": 0.302003, "p": 0.419331, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.35257, "se": 0.37396, "se_clustered": 0.272167, "se_greenland_robins": 0.37396, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "End stage renal disease": { "all": { "clustered_wider": false, "glp1_affected": 50, "glp1_at_risk": 93765, "hi": 1.07598, "lo": 0.515683, "log_rr": -0.294514, "p": 0.116498, "placebo_affected": 66, "placebo_at_risk": 67544, "rr": 0.744894, "se": 0.187631, "se_clustered": 0.117699, "se_greenland_robins": 0.187631, "strata_with_events": 6, "trials": 234, "trials_with_events": 6 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 1.20596, "lo": 0.331509, "log_rr": -0.458413, "p": 0.164074, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 0.632286, "se": 0.329438, "se_clustered": 0.167076, "se_greenland_robins": 0.329438, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 1.26707, "lo": 0.516829, "log_rr": -0.21167, "p": 0.354827, "placebo_affected": 42, "placebo_at_risk": 32526, "rr": 0.809232, "se": 0.228766, "se_clustered": 0.108883, "se_greenland_robins": 0.228766, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Endocarditis": { "all": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 2.32121, "lo": 0.483236, "log_rr": 0.0574193, "p": 0.885956, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.0591, "se": 0.400349, "se_clustered": 0.400349, "se_greenland_robins": 0.33811, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 4.84922, "lo": 0.509551, "log_rr": 0.452296, "p": 0.431327, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.57192, "se": 0.574767, "se_clustered": 0.574767, "se_greenland_robins": 0.483439, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 2.27442, "lo": 0.215573, "log_rr": -0.356367, "p": 0.553262, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.700216, "se": 0.601077, "se_clustered": 0.601077, "se_greenland_robins": 0.492596, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Endometrial adenocarcinoma": { "all": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.18028, "lo": 0.330081, "log_rr": -0.471333, "p": 0.147048, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 0.62417, "se": 0.325048, "se_clustered": 0.325048, "se_greenland_robins": 0.298583, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 0.896063, "lo": 0.10818, "log_rr": -1.16685, "p": 0.0305074, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.311346, "se": 0.539349, "se_clustered": 0.312025, "se_greenland_robins": 0.539349, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.42757, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 2.13649, "lo": 0.422595, "log_rr": -0.0510885, "p": 0.901647, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.950195, "se": 0.413402, "se_clustered": 0.413402, "se_greenland_robins": 0.375111, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Endometrial cancer": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.40906, "lo": 0.561202, "log_rr": 0.324382, "p": 0.480929, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.38318, "se": 0.460241, "se_clustered": 0.409128, "se_greenland_robins": 0.460241, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 7.45652, "lo": 0.151074, "log_rr": 0.0595521, "p": 0.952259, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 1.06136, "se": 0.99468, "se_clustered": 0.99468, "se_greenland_robins": 0.835798, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 4.63563, "lo": 0.527648, "log_rr": 0.447223, "p": 0.419827, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.56396, "se": 0.554372, "se_clustered": 0.373635, "se_greenland_robins": 0.554372, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Endometrial hyperplasia": { "all": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 5.2297, "lo": 0.481887, "log_rr": 0.462154, "p": 0.447389, "placebo_affected": 7, "placebo_at_risk": 67544, "rr": 1.58749, "se": 0.608276, "se_clustered": 0.608276, "se_greenland_robins": 0.473215, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 34.2343, "lo": 0.617145, "log_rr": 1.52529, "p": 0.136528, "placebo_affected": 2, "placebo_at_risk": 35018, "rr": 4.59647, "se": 1.02448, "se_clustered": 1.02448, "se_greenland_robins": 0.826097, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.697511, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 2.97907, "lo": 0.0883371, "log_rr": -0.667492, "p": 0.457053, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.512994, "se": 0.897518, "se_clustered": 0.897518, "se_greenland_robins": 0.704644, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Epididymitis": { "all": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 4.58963, "lo": 0.704588, "log_rr": 0.586829, "p": 0.219622, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.79828, "se": 0.478055, "se_clustered": 0.478055, "se_greenland_robins": 0.42751, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 7.96994, "lo": 0.784352, "log_rr": 0.91639, "p": 0.121308, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 2.50025, "se": 0.591484, "se_clustered": 0.312124, "se_greenland_robins": 0.591484, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.665905, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 9.35748, "lo": 0.141772, "log_rr": 0.14132, "p": 0.89481, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.15179, "se": 1.06882, "se_clustered": 1.06882, "se_greenland_robins": 0.639397, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Epilepsy": { "all": { "clustered_wider": true, "glp1_affected": 28, "glp1_at_risk": 93765, "hi": 1.69664, "lo": 0.40104, "log_rr": -0.192523, "p": 0.600815, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 0.824876, "se": 0.367951, "se_clustered": 0.367951, "se_greenland_robins": 0.280342, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 1.85827, "lo": 0.393582, "log_rr": -0.15641, "p": 0.692828, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.855209, "se": 0.395954, "se_clustered": 0.395954, "se_greenland_robins": 0.386722, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 2.95191, "lo": 0.212698, "log_rr": -0.232716, "p": 0.728733, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.792379, "se": 0.671016, "se_clustered": 0.671016, "se_greenland_robins": 0.407135, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Epistaxis": { "all": { "clustered_wider": true, "glp1_affected": 31, "glp1_at_risk": 93765, "hi": 1.64432, "lo": 0.551656, "log_rr": -0.0487504, "p": 0.861101, "placebo_affected": 31, "placebo_at_risk": 67544, "rr": 0.952419, "se": 0.278618, "se_clustered": 0.278618, "se_greenland_robins": 0.250912, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 47388, "hi": 2.49268, "lo": 0.649872, "log_rr": 0.241189, "p": 0.481882, "placebo_affected": 17, "placebo_at_risk": 35018, "rr": 1.27276, "se": 0.34295, "se_clustered": 0.34295, "se_greenland_robins": 0.315475, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.31533, "lo": 0.237407, "log_rr": -0.581945, "p": 0.182724, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.558811, "se": 0.43676, "se_clustered": 0.415484, "se_greenland_robins": 0.43676, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Erysipelas": { "all": { "clustered_wider": false, "glp1_affected": 67, "glp1_at_risk": 93765, "hi": 1.08153, "lo": 0.552993, "log_rr": -0.257018, "p": 0.133107, "placebo_affected": 79, "placebo_at_risk": 67544, "rr": 0.773354, "se": 0.171122, "se_clustered": 0.108368, "se_greenland_robins": 0.171122, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 36, "glp1_at_risk": 47388, "hi": 1.03707, "lo": 0.426251, "log_rr": -0.408164, "p": 0.0719417, "placebo_affected": 49, "placebo_at_risk": 35018, "rr": 0.66487, "se": 0.226822, "se_clustered": 0.120254, "se_greenland_robins": 0.226822, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 46377, "hi": 1.5938, "lo": 0.56832, "log_rr": -0.0494756, "p": 0.850818, "placebo_affected": 30, "placebo_at_risk": 32526, "rr": 0.951728, "se": 0.263064, "se_clustered": 0.221814, "se_greenland_robins": 0.263064, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Escherichia sepsis": { "all": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 3.48937, "lo": 0.40257, "log_rr": 0.169917, "p": 0.757764, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.18521, "se": 0.55093, "se_clustered": 0.55093, "se_greenland_robins": 0.455072, "strata_with_events": 6, "trials": 234, "trials_with_events": 6 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 3.69325, "lo": 0.270744, "log_rr": -3.78709e-05, "p": 0.999955, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.999962, "se": 0.666616, "se_clustered": 0.666616, "se_greenland_robins": 0.577122, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 13.1961, "lo": 0.183429, "log_rr": 0.441997, "p": 0.685327, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 1.55581, "se": 1.0908, "se_clustered": 1.0908, "se_greenland_robins": 0.750737, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Escherichia urinary tract infection": { "all": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 2.37448, "lo": 0.606144, "log_rr": 0.18207, "p": 0.601184, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.1997, "se": 0.348327, "se_clustered": 0.255094, "se_greenland_robins": 0.348327, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 3.28147, "lo": 0.545889, "log_rr": 0.291477, "p": 0.524116, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.3384, "se": 0.457567, "se_clustered": 0.324138, "se_greenland_robins": 0.457567, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.875223, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 2.95068, "lo": 0.355704, "log_rr": 0.0241899, "p": 0.964252, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.02448, "se": 0.539727, "se_clustered": 0.515086, "se_greenland_robins": 0.539727, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Extremity necrosis": { "all": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 93765, "hi": 2.89575, "lo": 0.88803, "log_rr": 0.472248, "p": 0.117314, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.60359, "se": 0.301535, "se_clustered": 0.227075, "se_greenland_robins": 0.301535, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 11.2978, "lo": 1.24528, "log_rr": 1.32198, "p": 0.0187791, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 3.75086, "se": 0.562573, "se_clustered": 0.393594, "se_greenland_robins": 0.562573, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.365123, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 2.06017, "lo": 0.461708, "log_rr": -0.0250176, "p": 0.94772, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 0.975293, "se": 0.38154, "se_clustered": 0.222368, "se_greenland_robins": 0.38154, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Facial bones fracture": { "all": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.74493, "lo": 0.315053, "log_rr": -0.299151, "p": 0.493301, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.741447, "se": 0.436673, "se_clustered": 0.356177, "se_greenland_robins": 0.436673, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.5594, "lo": 0.145316, "log_rr": -0.742272, "p": 0.220171, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.476031, "se": 0.605405, "se_clustered": 0.479386, "se_greenland_robins": 0.605405, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 4.6685, "lo": 0.336853, "log_rr": 0.226366, "p": 0.735721, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.25403, "se": 0.670662, "se_clustered": 0.100901, "se_greenland_robins": 0.670662, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Facial paralysis": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 1.74906, "lo": 0.408663, "log_rr": -0.167892, "p": 0.650802, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.845445, "se": 0.370911, "se_clustered": 0.289902, "se_greenland_robins": 0.370911, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 3.93568, "lo": 0.122809, "log_rr": -0.36352, "p": 0.681083, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 0.695225, "se": 0.884508, "se_clustered": 0.884508, "se_greenland_robins": 0.773218, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 2.03958, "lo": 0.388869, "log_rr": -0.115884, "p": 0.784007, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.890579, "se": 0.422778, "se_clustered": 0.315004, "se_greenland_robins": 0.422778, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Fall": { "all": { "clustered_wider": true, "glp1_affected": 358, "glp1_at_risk": 93765, "hi": 1.10129, "lo": 0.799195, "log_rr": -0.0638319, "p": 0.435172, "placebo_affected": 371, "placebo_at_risk": 67544, "rr": 0.938163, "se": 0.0817968, "se_clustered": 0.0817968, "se_greenland_robins": 0.0740158, "strata_with_events": 31, "trials": 234, "trials_with_events": 31 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 182, "glp1_at_risk": 47388, "hi": 1.28113, "lo": 0.701293, "log_rr": -0.0535429, "p": 0.727605, "placebo_affected": 187, "placebo_at_risk": 35018, "rr": 0.947865, "se": 0.153721, "se_clustered": 0.153721, "se_greenland_robins": 0.103647, "strata_with_events": 18, "trials": 117, "trials_with_events": 18 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 176, "glp1_at_risk": 46377, "hi": 1.14194, "lo": 0.754468, "log_rr": -0.0745057, "p": 0.481032, "placebo_affected": 184, "placebo_at_risk": 32526, "rr": 0.928202, "se": 0.105735, "se_clustered": 0.044485, "se_greenland_robins": 0.105735, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Fatigue": { "all": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 7.26422, "lo": 0.785041, "log_rr": 0.870471, "p": 0.125133, "placebo_affected": 6, "placebo_at_risk": 67544, "rr": 2.38803, "se": 0.567607, "se_clustered": 0.567607, "se_greenland_robins": 0.491686, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 8.46521, "lo": 0.472617, "log_rr": 0.693248, "p": 0.346299, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 2.0002, "se": 0.736093, "se_clustered": 0.736093, "se_greenland_robins": 0.612298, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 20.9474, "lo": 0.478, "log_rr": 1.15194, "p": 0.232272, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 3.16431, "se": 0.964345, "se_clustered": 0.964345, "se_greenland_robins": 0.833256, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Femoral neck fracture": { "all": { "clustered_wider": false, "glp1_affected": 44, "glp1_at_risk": 93765, "hi": 1.37222, "lo": 0.604299, "log_rr": -0.0936282, "p": 0.654503, "placebo_affected": 48, "placebo_at_risk": 67544, "rr": 0.910621, "se": 0.209217, "se_clustered": 0.188583, "se_greenland_robins": 0.209217, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 26, "glp1_at_risk": 47388, "hi": 1.36313, "lo": 0.484658, "log_rr": -0.207264, "p": 0.432061, "placebo_affected": 32, "placebo_at_risk": 35018, "rr": 0.812805, "se": 0.263805, "se_clustered": 0.21963, "se_greenland_robins": 0.263805, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 2.18009, "lo": 0.561507, "log_rr": 0.101117, "p": 0.770132, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 1.10641, "se": 0.346051, "se_clustered": 0.322241, "se_greenland_robins": 0.346051, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Femur fracture": { "all": { "clustered_wider": true, "glp1_affected": 79, "glp1_at_risk": 93765, "hi": 1.30857, "lo": 0.58495, "log_rr": -0.133648, "p": 0.515265, "placebo_affected": 86, "placebo_at_risk": 67544, "rr": 0.874898, "se": 0.205403, "se_clustered": 0.205403, "se_greenland_robins": 0.158862, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 36, "glp1_at_risk": 47388, "hi": 1.61423, "lo": 0.379838, "log_rr": -0.244576, "p": 0.507576, "placebo_affected": 45, "placebo_at_risk": 35018, "rr": 0.783037, "se": 0.369106, "se_clustered": 0.369106, "se_greenland_robins": 0.225551, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.870131, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 43, "glp1_at_risk": 46377, "hi": 1.51505, "lo": 0.628503, "log_rr": -0.0244821, "p": 0.913146, "placebo_affected": 41, "placebo_at_risk": 32526, "rr": 0.975815, "se": 0.224459, "se_clustered": 0.178923, "se_greenland_robins": 0.224459, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Fibula fracture": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 2.56346, "lo": 0.637638, "log_rr": 0.245687, "p": 0.488818, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.2785, "se": 0.354941, "se_clustered": 0.210796, "se_greenland_robins": 0.354941, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 6.49252, "lo": 0.565397, "log_rr": 0.650212, "p": 0.296389, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.91595, "se": 0.622684, "se_clustered": 0.433035, "se_greenland_robins": 0.622684, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.826685, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.43775, "lo": 0.436625, "log_rr": 0.031196, "p": 0.943313, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.03169, "se": 0.438721, "se_clustered": 0.252199, "se_greenland_robins": 0.438721, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Fluid overload": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 3.59725, "lo": 0.674315, "log_rr": 0.443056, "p": 0.299576, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.55746, "se": 0.427107, "se_clustered": 0.279978, "se_greenland_robins": 0.427107, "strata_with_events": 5, "trials": 234, "trials_with_events": 5 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 6.64288, "lo": 0.603181, "log_rr": 0.694004, "p": 0.256815, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 2.00171, "se": 0.612023, "se_clustered": null, "se_greenland_robins": 0.612023, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.93762, "lo": 0.366854, "log_rr": 0.183893, "p": 0.761338, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.20189, "se": 0.605462, "se_clustered": 0.518749, "se_greenland_robins": 0.605462, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Foot deformity": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.30238, "lo": 0.418536, "log_rr": -0.018526, "p": 0.966025, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.981645, "se": 0.43494, "se_clustered": 0.416922, "se_greenland_robins": 0.43494, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 1.91397, "lo": 0.18724, "log_rr": -0.513092, "p": 0.386908, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.598642, "se": 0.593007, "se_clustered": 0.502212, "se_greenland_robins": 0.593007, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 7.99792, "lo": 0.501559, "log_rr": 0.694574, "p": 0.325511, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.00286, "se": 0.706445, "se_clustered": 0.589466, "se_greenland_robins": 0.706445, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Foot fracture": { "all": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 1.32618, "lo": 0.417685, "log_rr": -0.295362, "p": 0.316279, "placebo_affected": 26, "placebo_at_risk": 67544, "rr": 0.744262, "se": 0.294733, "se_clustered": 0.20522, "se_greenland_robins": 0.294733, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.83263, "lo": 0.3793, "log_rr": -0.181838, "p": 0.650899, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 0.833737, "se": 0.401839, "se_clustered": 0.29529, "se_greenland_robins": 0.401839, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 1.5184, "lo": 0.275761, "log_rr": -0.435283, "p": 0.317197, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.647082, "se": 0.43518, "se_clustered": 0.331968, "se_greenland_robins": 0.43518, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Gangrene": { "all": { "clustered_wider": false, "glp1_affected": 62, "glp1_at_risk": 93765, "hi": 0.890882, "lo": 0.467992, "log_rr": -0.437424, "p": 0.00773288, "placebo_affected": 92, "placebo_at_risk": 67544, "rr": 0.645698, "se": 0.164228, "se_clustered": 0.0975706, "se_greenland_robins": 0.164228, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 1.01153, "lo": 0.413742, "log_rr": -0.435527, "p": 0.0561699, "placebo_affected": 48, "placebo_at_risk": 35018, "rr": 0.646924, "se": 0.228059, "se_clustered": 0.135938, "se_greenland_robins": 0.228059, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 46377, "hi": 1.02473, "lo": 0.4052, "log_rr": -0.439474, "p": 0.0633448, "placebo_affected": 44, "placebo_at_risk": 32526, "rr": 0.644375, "se": 0.236688, "se_clustered": 0.154469, "se_greenland_robins": 0.236688, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Gastric cancer": { "all": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 2.40997, "lo": 0.741863, "log_rr": 0.290512, "p": 0.333772, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.33711, "se": 0.300569, "se_clustered": 0.252126, "se_greenland_robins": 0.300569, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.54555, "lo": 0.342354, "log_rr": -0.0687807, "p": 0.893096, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.933531, "se": 0.51181, "se_clustered": 0.476093, "se_greenland_robins": 0.51181, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.973628, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 3.37163, "lo": 0.771969, "log_rr": 0.478293, "p": 0.20345, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.61332, "se": 0.37608, "se_clustered": 0.321745, "se_greenland_robins": 0.37608, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Gastric polyps": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.03779, "lo": 0.3849, "log_rr": -0.121452, "p": 0.775143, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.885634, "se": 0.425171, "se_clustered": 0.304645, "se_greenland_robins": 0.425171, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 2.55083, "lo": 0.288192, "log_rr": -0.153855, "p": 0.782101, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.857396, "se": 0.556272, "se_clustered": 0.300966, "se_greenland_robins": 0.556272, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.36838, "lo": 0.254114, "log_rr": -0.077771, "p": 0.906099, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.925176, "se": 0.659299, "se_clustered": 0.639302, "se_greenland_robins": 0.659299, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Gastric ulcer": { "all": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 1.25566, "lo": 0.479568, "log_rr": -0.253605, "p": 0.301692, "placebo_affected": 38, "placebo_at_risk": 67544, "rr": 0.775998, "se": 0.245548, "se_clustered": 0.149204, "se_greenland_robins": 0.245548, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 1.29999, "lo": 0.344595, "log_rr": -0.401515, "p": 0.235859, "placebo_affected": 22, "placebo_at_risk": 35018, "rr": 0.669306, "se": 0.338716, "se_clustered": 0.137574, "se_greenland_robins": 0.338716, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 1.85823, "lo": 0.455281, "log_rr": -0.083609, "p": 0.815742, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.919791, "se": 0.358799, "se_clustered": 0.253307, "se_greenland_robins": 0.358799, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Gastric ulcer haemorrhage": { "all": { "clustered_wider": true, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 3.16189, "lo": 0.723158, "log_rr": 0.413521, "p": 0.27188, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.51213, "se": 0.376358, "se_clustered": 0.376358, "se_greenland_robins": 0.284273, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 2.68703, "lo": 0.480248, "log_rr": 0.127491, "p": 0.771635, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.13597, "se": 0.439265, "se_clustered": 0.439265, "se_greenland_robins": 0.371183, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 6.93204, "lo": 0.721474, "log_rr": 0.804848, "p": 0.163202, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 2.23636, "se": 0.577208, "se_clustered": 0.577208, "se_greenland_robins": 0.456255, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Gastritis": { "all": { "clustered_wider": true, "glp1_affected": 85, "glp1_at_risk": 93765, "hi": 1.07507, "lo": 0.559081, "log_rr": -0.254536, "p": 0.127014, "placebo_affected": 97, "placebo_at_risk": 67544, "rr": 0.775276, "se": 0.166801, "se_clustered": 0.166801, "se_greenland_robins": 0.1533, "strata_with_events": 30, "trials": 234, "trials_with_events": 30 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 51, "glp1_at_risk": 47388, "hi": 1.61856, "lo": 0.58958, "log_rr": -0.0234053, "p": 0.927612, "placebo_affected": 48, "placebo_at_risk": 35018, "rr": 0.976867, "se": 0.257627, "se_clustered": 0.257627, "se_greenland_robins": 0.2071, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.989261, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 0.919303, "lo": 0.369973, "log_rr": -0.539232, "p": 0.0202151, "placebo_affected": 49, "placebo_at_risk": 32526, "rr": 0.583196, "se": 0.232195, "se_clustered": 0.180894, "se_greenland_robins": 0.232195, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 } }, "Gastritis erosive": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 1.58532, "lo": 0.315645, "log_rr": -0.346175, "p": 0.400462, "placebo_affected": 23, "placebo_at_risk": 67544, "rr": 0.707389, "se": 0.411722, "se_clustered": 0.411722, "se_greenland_robins": 0.310286, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 2.44001, "lo": 0.230723, "log_rr": -0.287267, "p": 0.633048, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.750312, "se": 0.60168, "se_clustered": 0.60168, "se_greenland_robins": 0.381759, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.917467, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 1.87855, "lo": 0.205964, "log_rr": -0.474779, "p": 0.399835, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.622022, "se": 0.563927, "se_clustered": 0.563927, "se_greenland_robins": 0.531725, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Gastroenteritis": { "all": { "clustered_wider": false, "glp1_affected": 181, "glp1_at_risk": 93765, "hi": 1.797, "lo": 1.10765, "log_rr": 0.344182, "p": 0.0052997, "placebo_affected": 112, "placebo_at_risk": 67544, "rr": 1.41083, "se": 0.123441, "se_clustered": 0.103734, "se_greenland_robins": 0.123441, "strata_with_events": 45, "trials": 234, "trials_with_events": 44 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 107, "glp1_at_risk": 47388, "hi": 1.77649, "lo": 0.972099, "log_rr": 0.27317, "p": 0.0757349, "placebo_affected": 75, "placebo_at_risk": 35018, "rr": 1.31412, "se": 0.153813, "se_clustered": 0.0923911, "se_greenland_robins": 0.153813, "strata_with_events": 21, "trials": 117, "trials_with_events": 20 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 74, "glp1_at_risk": 46377, "hi": 2.39936, "lo": 1.06395, "log_rr": 0.468594, "p": 0.0238993, "placebo_affected": 37, "placebo_at_risk": 32526, "rr": 1.59775, "se": 0.207458, "se_clustered": 0.196054, "se_greenland_robins": 0.207458, "strata_with_events": 24, "trials": 117, "trials_with_events": 24 } }, "Gastroenteritis viral": { "all": { "clustered_wider": true, "glp1_affected": 26, "glp1_at_risk": 93765, "hi": 2.15403, "lo": 0.520369, "log_rr": 0.0570619, "p": 0.874884, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.05872, "se": 0.362394, "se_clustered": 0.362394, "se_greenland_robins": 0.287025, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 3.1067, "lo": 0.385857, "log_rr": 0.090636, "p": 0.864749, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.09487, "se": 0.532115, "se_clustered": 0.532115, "se_greenland_robins": 0.386085, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.959593, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.65931, "lo": 0.387805, "log_rr": 0.0154076, "p": 0.974975, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 1.01553, "se": 0.491162, "se_clustered": 0.491162, "se_greenland_robins": 0.42932, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Gastrointestinal haemorrhage": { "all": { "clustered_wider": true, "glp1_affected": 123, "glp1_at_risk": 93765, "hi": 1.166, "lo": 0.711955, "log_rr": -0.0930826, "p": 0.459518, "placebo_affected": 132, "placebo_at_risk": 67544, "rr": 0.911118, "se": 0.125848, "se_clustered": 0.125848, "se_greenland_robins": 0.125451, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 57, "glp1_at_risk": 47388, "hi": 1.65079, "lo": 0.605236, "log_rr": -0.0004406, "p": 0.998627, "placebo_affected": 56, "placebo_at_risk": 35018, "rr": 0.999559, "se": 0.255972, "se_clustered": 0.255972, "se_greenland_robins": 0.188051, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 66, "glp1_at_risk": 46377, "hi": 1.17743, "lo": 0.60787, "log_rr": -0.167228, "p": 0.321435, "placebo_affected": 76, "placebo_at_risk": 32526, "rr": 0.846007, "se": 0.168659, "se_clustered": 0.0675633, "se_greenland_robins": 0.168659, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Gastrooesophageal reflux disease": { "all": { "clustered_wider": false, "glp1_affected": 71, "glp1_at_risk": 93765, "hi": 1.7215, "lo": 0.848212, "log_rr": 0.189287, "p": 0.294514, "placebo_affected": 54, "placebo_at_risk": 67544, "rr": 1.20839, "se": 0.180571, "se_clustered": 0.154115, "se_greenland_robins": 0.180571, "strata_with_events": 27, "trials": 234, "trials_with_events": 26 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 36, "glp1_at_risk": 47388, "hi": 1.52685, "lo": 0.617454, "log_rr": -0.0294725, "p": 0.89846, "placebo_affected": 35, "placebo_at_risk": 35018, "rr": 0.970958, "se": 0.230963, "se_clustered": 0.128128, "se_greenland_robins": 0.230963, "strata_with_events": 14, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.973628, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 35, "glp1_at_risk": 46377, "hi": 3.23052, "lo": 0.861355, "log_rr": 0.511696, "p": 0.12917, "placebo_affected": 19, "placebo_at_risk": 32526, "rr": 1.66812, "se": 0.337223, "se_clustered": 0.337223, "se_greenland_robins": 0.29535, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "General physical 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3.14409, "se": 1.23273, "se_clustered": 1.23273, "se_greenland_robins": 0.821292, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Generalised oedema": { "all": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 93765, "hi": 1.68526, "lo": 0.225115, "log_rr": -0.484612, "p": 0.345344, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.615936, "se": 0.513545, "se_clustered": 0.513545, "se_greenland_robins": 0.44916, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 4.9559, "lo": 0.201995, "log_rr": 0.00053314, "p": 0.999479, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 1.00053, "se": 0.816365, "se_clustered": 0.577372, "se_greenland_robins": 0.816365, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.00273, "lo": 0.125117, "log_rr": -0.691996, "p": 0.327974, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.500576, "se": 0.707416, "se_clustered": 0.707416, "se_greenland_robins": 0.547396, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Glaucoma": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 0.985942, "lo": 0.240077, "log_rr": -0.720476, "p": 0.0455812, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 0.48652, "se": 0.360373, "se_clustered": 0.246122, "se_greenland_robins": 0.360373, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.80593, "lo": 0.175274, "log_rr": -0.575166, "p": 0.333737, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.562612, "se": 0.595031, "se_clustered": 0.360094, "se_greenland_robins": 0.595031, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.0915, "lo": 0.184264, "log_rr": -0.801915, "p": 0.0772222, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.448469, "se": 0.453819, "se_clustered": 0.339108, "se_greenland_robins": 0.453819, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Goitre": { "all": { "clustered_wider": false, "glp1_affected": 48, "glp1_at_risk": 93765, "hi": 2.33872, "lo": 0.903608, "log_rr": 0.374122, "p": 0.123036, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 1.45371, "se": 0.242597, "se_clustered": 0.14066, "se_greenland_robins": 0.242597, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 2.95609, "lo": 0.694808, "log_rr": 0.359873, "p": 0.329941, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 1.43315, "se": 0.369391, "se_clustered": 0.161762, "se_greenland_robins": 0.369391, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 46377, "hi": 2.75793, "lo": 0.782082, "log_rr": 0.384342, "p": 0.231913, "placebo_affected": 17, "placebo_at_risk": 32526, "rr": 1.46865, "se": 0.321505, "se_clustered": 0.220009, "se_greenland_robins": 0.321505, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Gout": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.35252, "lo": 0.403522, "log_rr": -0.302778, "p": 0.326448, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 0.738763, "se": 0.30855, "se_clustered": 0.235361, "se_greenland_robins": 0.30855, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 1.70948, "lo": 0.288106, "log_rr": -0.35412, "p": 0.435641, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.701791, "se": 0.454247, "se_clustered": 0.263142, "se_greenland_robins": 0.454247, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.848267, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 1.75593, "lo": 0.337934, "log_rr": -0.260954, "p": 0.53477, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 0.770316, "se": 0.420391, "se_clustered": 0.386636, "se_greenland_robins": 0.420391, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Haematochezia": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.284, "lo": 0.426782, "log_rr": 0.168791, "p": 0.745748, "placebo_affected": 11, "placebo_at_risk": 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"glp1_affected": 29, "glp1_at_risk": 93765, "hi": 3.67226, "lo": 0.81178, "log_rr": 0.546141, "p": 0.156075, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 1.72658, "se": 0.385041, "se_clustered": 0.385041, "se_greenland_robins": 0.310967, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 2.2727, "lo": 0.37068, "log_rr": -0.0857231, "p": 0.85299, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.917848, "se": 0.462607, "se_clustered": 0.274902, "se_greenland_robins": 0.462607, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.959593, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 7.84371, "lo": 1.15055, "log_rr": 1.09997, "p": 0.0246813, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 3.00409, "se": 0.489671, "se_clustered": 0.489671, "se_greenland_robins": 0.454634, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Haematuria": { "all": { "clustered_wider": false, "glp1_affected": 55, "glp1_at_risk": 93765, "hi": 1.59065, "lo": 0.74163, "log_rr": 0.0826207, "p": 0.671247, "placebo_affected": 49, "placebo_at_risk": 67544, "rr": 1.08613, "se": 0.194659, "se_clustered": 0.178824, "se_greenland_robins": 0.194659, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 36, "glp1_at_risk": 47388, "hi": 2.21119, "lo": 0.821256, "log_rr": 0.298304, "p": 0.237759, "placebo_affected": 26, "placebo_at_risk": 35018, "rr": 1.34757, "se": 0.25267, "se_clustered": 0.165057, "se_greenland_robins": 0.25267, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 1.44978, "lo": 0.426781, "log_rr": -0.240038, "p": 0.441638, "placebo_affected": 23, "placebo_at_risk": 32526, "rr": 0.786598, "se": 0.311968, "se_clustered": 0.282409, "se_greenland_robins": 0.311968, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Haemoptysis": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 2.18546, "lo": 0.502481, "log_rr": 0.0468155, "p": 0.900653, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.04793, "se": 0.375013, "se_clustered": 0.299049, "se_greenland_robins": 0.375013, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 2.46088, "lo": 0.376596, "log_rr": -0.0380314, "p": 0.936698, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.962683, "se": 0.478862, "se_clustered": 0.467166, "se_greenland_robins": 0.478862, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.992477, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.93501, "lo": 0.366826, "log_rr": 0.183523, "p": 0.761748, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.20144, "se": 0.605313, "se_clustered": 0.373595, "se_greenland_robins": 0.605313, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Haemorrhage intracranial": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 1.97238, "lo": 0.460768, "log_rr": -0.0478106, "p": 0.897447, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.953314, "se": 0.37095, "se_clustered": 0.309157, "se_greenland_robins": 0.37095, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 2.91877, "lo": 0.43451, "log_rr": 0.118814, "p": 0.806827, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.12616, "se": 0.485901, "se_clustered": 0.401148, "se_greenland_robins": 0.485901, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.937672, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.36004, "lo": 0.242054, "log_rr": -0.279959, "p": 0.629876, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.755815, "se": 0.580948, "se_clustered": 0.473845, "se_greenland_robins": 0.580948, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Haemorrhagic anaemia": { "all": { "clustered_wider": false, "glp1_affected": 39, "glp1_at_risk": 93765, "hi": 2.20283, "lo": 0.825184, "log_rr": 0.298796, "p": 0.232924, "placebo_affected": 28, "placebo_at_risk": 67544, "rr": 1.34823, "se": 0.250487, "se_clustered": 0.237815, "se_greenland_robins": 0.250487, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 24, "glp1_at_risk": 47388, "hi": 2.06801, "lo": 0.620534, "log_rr": 0.124706, "p": 0.684676, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.13281, "se": 0.307088, "se_clustered": 0.307088, "se_greenland_robins": 0.299922, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 4.98873, "lo": 0.797407, "log_rr": 0.690396, "p": 0.139951, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.9945, "se": 0.467757, "se_clustered": 0.434015, "se_greenland_robins": 0.467757, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Haemorrhagic stroke": { "all": { "clustered_wider": false, "glp1_affected": 45, "glp1_at_risk": 93765, "hi": 1.48126, "lo": 0.634227, "log_rr": -0.0312259, "p": 0.885262, "placebo_affected": 44, "placebo_at_risk": 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false, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 3.79756, "lo": 1.02774, "log_rr": 0.680861, "p": 0.0411486, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.97558, "se": 0.333424, "se_clustered": 0.307579, "se_greenland_robins": 0.333424, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 3.78608, "lo": 0.675358, "log_rr": 0.46941, "p": 0.285785, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 1.59905, "se": 0.439764, "se_clustered": 0.439764, "se_greenland_robins": 0.408277, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.823828, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 9.32169, "lo": 0.913075, "log_rr": 1.0707, "p": 0.0708354, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 2.91743, "se": 0.592685, "se_clustered": 0.2611, "se_greenland_robins": 0.592685, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Haemothorax": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.92982, "lo": 0.360076, "log_rr": -0.182008, "p": 0.670863, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.833595, "se": 0.42829, "se_clustered": 0.422192, "se_greenland_robins": 0.42829, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.41234, "lo": 0.31725, "log_rr": -0.133734, "p": 0.79609, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.874823, "se": 0.517526, "se_clustered": 0.33876, "se_greenland_robins": 0.517526, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 8.77961, "lo": 0.0642414, "log_rr": -0.286338, "p": 0.819453, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 0.751009, "se": 1.2545, "se_clustered": 1.2545, "se_greenland_robins": 0.764456, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Hand fracture": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 1.54436, "lo": 0.347211, "log_rr": -0.311606, "p": 0.413104, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.73227, "se": 0.38073, "se_clustered": 0.259928, "se_greenland_robins": 0.38073, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.03177, "lo": 0.270094, "log_rr": -0.300038, "p": 0.559995, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.74079, "se": 0.514778, "se_clustered": 0.207903, "se_greenland_robins": 0.514778, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.18751, "lo": 0.238234, "log_rr": -0.325869, "p": 0.564543, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.7219, "se": 0.56564, "se_clustered": 0.54333, "se_greenland_robins": 0.56564, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Head injury": { "all": { "clustered_wider": true, "glp1_affected": 38, "glp1_at_risk": 93765, "hi": 1.91211, "lo": 0.73091, "log_rr": 0.167372, "p": 0.495091, "placebo_affected": 31, "placebo_at_risk": 67544, "rr": 1.18219, "se": 0.245329, "se_clustered": 0.245329, "se_greenland_robins": 0.241569, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 28, "glp1_at_risk": 47388, "hi": 2.1733, "lo": 0.627023, "log_rr": 0.154738, "p": 0.625568, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 1.16735, "se": 0.317102, "se_clustered": 0.317102, "se_greenland_robins": 0.278077, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.91521, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 3.19896, "lo": 0.4727, "log_rr": 0.206765, "p": 0.671656, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.22969, "se": 0.487794, "se_clustered": 0.406916, "se_greenland_robins": 0.487794, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Headache": { "all": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 1.47291, "lo": 0.547228, "log_rr": -0.107825, "p": 0.669466, "placebo_affected": 32, "placebo_at_risk": 67544, "rr": 0.897784, "se": 0.252589, "se_clustered": 0.252287, "se_greenland_robins": 0.252589, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 1.47943, "lo": 0.372191, "log_rr": -0.298345, "p": 0.396742, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.742045, "se": 0.352049, "se_clustered": 0.352049, "se_greenland_robins": 0.321856, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 2.72409, "lo": 0.536041, "log_rr": 0.189294, "p": 0.648075, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 1.2084, "se": 0.414721, "se_clustered": 0.253749, "se_greenland_robins": 0.414721, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Hemiparesis": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 1.88366, "lo": 0.399759, "log_rr": -0.141838, "p": 0.719834, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.867762, "se": 0.395443, "se_clustered": 0.395443, "se_greenland_robins": 0.378701, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 2.76405, "lo": 0.457098, "log_rr": 0.116919, "p": 0.798969, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.12403, "se": 0.459078, "se_clustered": 0.390599, "se_greenland_robins": 0.459078, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 2.23321, "lo": 0.112058, "log_rr": -0.692652, "p": 0.364188, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.500248, "se": 0.763325, "se_clustered": 0.763325, "se_greenland_robins": 0.707132, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Hepatic cancer": { "all": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 1.60259, "lo": 0.364127, "log_rr": -0.269315, "p": 0.476213, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 0.763902, "se": 0.378036, "se_clustered": 0.378036, "se_greenland_robins": 0.350011, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 7.99778, "lo": 0.500496, "log_rr": 0.693504, "p": 0.326624, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 2.00071, "se": 0.706982, "se_clustered": 0.500071, "se_greenland_robins": 0.706982, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.842691, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 1.22717, "lo": 0.230486, "log_rr": -0.631428, "p": 0.138843, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.531832, "se": 0.426608, "se_clustered": 0.334429, "se_greenland_robins": 0.426608, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Hepatic cirrhosis": { "all": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 1.49051, "lo": 0.547194, "log_rr": -0.101917, "p": 0.690126, "placebo_affected": 32, "placebo_at_risk": 67544, "rr": 0.903104, "se": 0.255634, "se_clustered": 0.168098, "se_greenland_robins": 0.255634, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 1.46437, "lo": 0.384154, "log_rr": -0.287645, "p": 0.399438, "placebo_affected": 20, "placebo_at_risk": 35018, "rr": 0.750028, "se": 0.341367, "se_clustered": 0.304393, "se_greenland_robins": 0.341367, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 2.47093, "lo": 0.534266, "log_rr": 0.138865, "p": 0.722259, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.14897, "se": 0.390684, "se_clustered": 0.154287, "se_greenland_robins": 0.390684, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Hepatic encephalopathy": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.12288, "lo": 0.363915, "log_rr": -0.129032, "p": 0.774269, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.878946, "se": 0.449908, "se_clustered": 0.449908, "se_greenland_robins": 0.384089, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 7.19546, "lo": 0.0347244, "log_rr": -0.693431, "p": 0.610317, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.499858, "se": 1.36068, "se_clustered": 1.36068, "se_greenland_robins": 0.706703, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 2.89103, "lo": 0.458507, "log_rr": 0.140916, "p": 0.764192, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.15133, "se": 0.469752, "se_clustered": 0.384561, "se_greenland_robins": 0.469752, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Hepatocellular carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 48, "glp1_at_risk": 93765, "hi": 1.6166, "lo": 0.71221, "log_rr": 0.070473, "p": 0.736111, "placebo_affected": 43, "placebo_at_risk": 67544, "rr": 1.07302, "se": 0.209114, "se_clustered": 0.200046, "se_greenland_robins": 0.209114, "strata_with_events": 15, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 47388, "hi": 2.05577, "lo": 0.750265, "log_rr": 0.21666, "p": 0.399469, "placebo_affected": 27, "placebo_at_risk": 35018, "rr": 1.24192, "se": 0.257142, "se_clustered": 0.155124, "se_greenland_robins": 0.257142, "strata_with_events": 8, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 2.27748, "lo": 0.279072, "log_rr": -0.226609, "p": 0.672204, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.797233, "se": 0.53556, "se_clustered": 0.53556, "se_greenland_robins": 0.365173, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Herpes zoster": { "all": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 1.6519, "lo": 0.378318, "log_rr": -0.235047, "p": 0.531903, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 0.790533, "se": 0.376013, "se_clustered": 0.376013, "se_greenland_robins": 0.341193, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 2.03543, "lo": 0.306988, "log_rr": -0.235119, "p": 0.626103, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.790476, "se": 0.482574, "se_clustered": 0.414522, "se_greenland_robins": 0.482574, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.91521, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 2.8617, "lo": 0.218413, "log_rr": -0.234975, "p": 0.720335, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.790591, "se": 0.656335, "se_clustered": 0.656335, "se_greenland_robins": 0.482465, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Hiatus hernia": { "all": { "clustered_wider": true, "glp1_affected": 31, "glp1_at_risk": 93765, "hi": 3.06047, "lo": 0.521013, "log_rr": 0.233295, "p": 0.605501, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.26275, "se": 0.451679, "se_clustered": 0.451679, "se_greenland_robins": 0.307892, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 2.41304, "lo": 0.200864, "log_rr": -0.36212, "p": 0.568007, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.696199, "se": 0.634198, "se_clustered": 0.634198, "se_greenland_robins": 0.443902, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 46377, "hi": 5.87601, "lo": 0.912152, "log_rr": 0.839464, "p": 0.0773159, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 2.31513, "se": 0.475219, "se_clustered": 0.475219, "se_greenland_robins": 0.46663, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Hip fracture": { "all": { "clustered_wider": true, "glp1_affected": 77, "glp1_at_risk": 93765, "hi": 1.98151, "lo": 0.743177, "log_rr": 0.193518, "p": 0.439213, "placebo_affected": 60, "placebo_at_risk": 67544, "rr": 1.21351, "se": 0.250178, "se_clustered": 0.250178, "se_greenland_robins": 0.174387, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 30, "glp1_at_risk": 47388, "hi": 2.11446, "lo": 0.427941, "log_rr": -0.0499861, "p": 0.902384, "placebo_affected": 31, "placebo_at_risk": 35018, "rr": 0.951243, "se": 0.40755, "se_clustered": 0.40755, "se_greenland_robins": 0.256327, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.974122, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 47, "glp1_at_risk": 46377, "hi": 2.97058, "lo": 0.74986, "log_rr": 0.400445, "p": 0.254177, "placebo_affected": 29, "placebo_at_risk": 32526, "rr": 1.49249, "se": 0.351187, "se_clustered": 0.351187, "se_greenland_robins": 0.240675, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Humerus fracture": { "all": { "clustered_wider": false, "glp1_affected": 61, "glp1_at_risk": 93765, "hi": 1.03851, "lo": 0.517443, "log_rr": -0.310536, "p": 0.0805755, "placebo_affected": 75, "placebo_at_risk": 67544, "rr": 0.733054, "se": 0.177717, "se_clustered": 0.159133, "se_greenland_robins": 0.177717, "strata_with_events": 26, "trials": 234, "trials_with_events": 26 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 47388, "hi": 0.852353, "lo": 0.278191, "log_rr": -0.719601, "p": 0.0117606, "placebo_affected": 38, "placebo_at_risk": 35018, "rr": 0.486946, "se": 0.285641, "se_clustered": 0.191034, "se_greenland_robins": 0.285641, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.319394, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 41, "glp1_at_risk": 46377, "hi": 1.54747, "lo": 0.622317, "log_rr": -0.0188422, "p": 0.935376, "placebo_affected": 37, "placebo_at_risk": 32526, "rr": 0.981334, "se": 0.232383, "se_clustered": 0.230477, "se_greenland_robins": 0.232383, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Hydronephrosis": { "all": { "clustered_wider": true, "glp1_affected": 26, "glp1_at_risk": 93765, "hi": 1.29485, "lo": 0.405866, "log_rr": -0.321667, "p": 0.277094, "placebo_affected": 33, "placebo_at_risk": 67544, "rr": 0.72494, "se": 0.295957, "se_clustered": 0.295957, "se_greenland_robins": 0.262072, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 2.54323, "lo": 0.532622, "log_rr": 0.151745, "p": 0.703591, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 1.16386, "se": 0.398828, "se_clustered": 0.398828, "se_greenland_robins": 0.354158, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 0.877124, "lo": 0.165975, "log_rr": -0.963513, "p": 0.0232887, "placebo_affected": 18, "placebo_at_risk": 32526, "rr": 0.38155, "se": 0.424705, "se_clustered": 0.328154, "se_greenland_robins": 0.424705, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Hyperglycaemia": { "all": { "clustered_wider": false, "glp1_affected": 186, "glp1_at_risk": 93765, "hi": 0.871666, "lo": 0.591064, "log_rr": -0.33159, "p": 0.000820261, "placebo_affected": 236, "placebo_at_risk": 67544, "rr": 0.717782, "se": 0.0991043, "se_clustered": 0.0685744, "se_greenland_robins": 0.0991043, "strata_with_events": 25, "trials": 234, "trials_with_events": 25 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 92, "glp1_at_risk": 47388, "hi": 1.0148, "lo": 0.578222, "log_rr": -0.266555, "p": 0.063225, "placebo_affected": 110, "placebo_at_risk": 35018, "rr": 0.766014, "se": 0.143494, "se_clustered": 0.101842, "se_greenland_robins": 0.143494, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 94, "glp1_at_risk": 46377, "hi": 0.884865, "lo": 0.516853, "log_rr": -0.391158, "p": 0.00434813, "placebo_affected": 126, "placebo_at_risk": 32526, "rr": 0.676273, "se": 0.137165, "se_clustered": 0.0678584, "se_greenland_robins": 0.137165, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Hyperglycaemic hyperosmolar nonketotic syndrome": { "all": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.02419, "lo": 0.21259, "log_rr": -0.762244, "p": 0.0573838, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.466618, "se": 0.401102, "se_clustered": 0.361566, "se_greenland_robins": 0.401102, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.78409, "lo": 0.125344, "log_rr": -0.748894, "p": 0.268969, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.472889, "se": 0.677463, "se_clustered": 0.677463, "se_greenland_robins": 0.628637, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 1.28038, "lo": 0.166693, "log_rr": -0.772222, "p": 0.137608, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.461986, "se": 0.5201, "se_clustered": 0.441084, "se_greenland_robins": 0.5201, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Hyperkalaemia": { "all": { "clustered_wider": true, "glp1_affected": 69, "glp1_at_risk": 93765, "hi": 0.831514, "lo": 0.446217, "log_rr": -0.495729, "p": 0.00179671, "placebo_affected": 109, "placebo_at_risk": 67544, "rr": 0.609127, "se": 0.158789, "se_clustered": 0.158789, "se_greenland_robins": 0.154796, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 34, "glp1_at_risk": 47388, "hi": 0.792949, "lo": 0.338764, "log_rr": -0.657224, "p": 0.00245135, "placebo_affected": 62, "placebo_at_risk": 35018, "rr": 0.518288, "se": 0.216957, "se_clustered": 0.216957, "se_greenland_robins": 0.216474, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.157651, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 46377, "hi": 1.12857, "lo": 0.470927, "log_rr": -0.316051, "p": 0.156336, "placebo_affected": 47, "placebo_at_risk": 32526, "rr": 0.729022, "se": 0.222963, "se_clustered": 0.150203, "se_greenland_robins": 0.222963, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Hypersensitivity": { "all": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 2.1677, "lo": 0.280698, "log_rr": -0.248405, "p": 0.633824, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.780044, "se": 0.521474, "se_clustered": 0.521474, "se_greenland_robins": 0.460264, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 1.77196, "lo": 0.0532704, "log_rr": -1.18015, "p": 0.186816, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 0.307234, "se": 0.894011, "se_clustered": 0.651113, "se_greenland_robins": 0.894011, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 4.87627, "lo": 0.321984, "log_rr": 0.225564, "p": 0.744913, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.25303, "se": 0.693287, "se_clustered": 0.693287, "se_greenland_robins": 0.575839, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Hypertension": { "all": { "clustered_wider": true, "glp1_affected": 144, "glp1_at_risk": 93765, "hi": 1.07536, "lo": 0.676195, "log_rr": -0.159311, "p": 0.178271, "placebo_affected": 154, "placebo_at_risk": 67544, "rr": 0.852731, "se": 0.118351, "se_clustered": 0.118351, "se_greenland_robins": 0.116521, "strata_with_events": 35, "trials": 234, "trials_with_events": 35 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 84, "glp1_at_risk": 47388, "hi": 1.28028, "lo": 0.694182, "log_rr": -0.0589711, "p": 0.705688, "placebo_affected": 85, "placebo_at_risk": 35018, "rr": 0.942734, "se": 0.156151, "se_clustered": 0.156151, "se_greenland_robins": 0.152475, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.931196, "replicated": false, "replication": { 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0.256489, "se_greenland_robins": 0.207786, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 49, "glp1_at_risk": 46377, "hi": 1.36689, "lo": 0.600151, "log_rr": -0.0990188, "p": 0.637241, "placebo_affected": 46, "placebo_at_risk": 32526, "rr": 0.905726, "se": 0.209981, "se_clustered": 0.156055, "se_greenland_robins": 0.209981, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Hypertensive emergency": { "all": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 2.0403, "lo": 0.552331, "log_rr": 0.0597455, "p": 0.857759, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 1.06157, "se": 0.333349, "se_clustered": 0.333349, "se_greenland_robins": 0.296244, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 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"trials_with_events": 3 } }, "Hypervolaemia": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 1.6335, "lo": 0.225578, "log_rr": -0.499182, "p": 0.32298, "placebo_affected": 28, "placebo_at_risk": 67544, "rr": 0.607027, "se": 0.505064, "se_clustered": 0.505064, "se_greenland_robins": 0.307099, "strata_with_events": 5, "trials": 234, "trials_with_events": 5 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 2.15598, "lo": 0.463847, "log_rr": 2.21896e-05, "p": 0.999955, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.00002, "se": 0.391957, "se_clustered": 0.376893, "se_greenland_robins": 0.391957, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 0.801427, "lo": 0.0886303, "log_rr": -1.32232, "p": 0.0185706, 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false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.86512, "lo": 0.369185, "log_rr": -0.186565, "p": 0.651634, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.829805, "se": 0.413218, "se_clustered": 0.32083, "se_greenland_robins": 0.413218, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 5.51418, "lo": 0.0453241, "log_rr": -0.693296, "p": 0.57137, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 0.499926, "se": 1.22483, "se_clustered": 1.22483, "se_greenland_robins": 0.866083, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Hypoxia": { "all": { "clustered_wider": true, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 1.27747, "lo": 0.358235, "log_rr": -0.390842, "p": 0.228211, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 0.676487, "se": 0.324355, "se_clustered": 0.324355, "se_greenland_robins": 0.288727, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 2.15693, "lo": 0.463829, "log_rr": 0.000223794, "p": 0.999545, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.00022, "se": 0.39208, "se_clustered": 0.210837, "se_greenland_robins": 0.39208, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.20364, "lo": 0.152725, "log_rr": -0.846882, "p": 0.107831, "placebo_affected": 17, "placebo_at_risk": 32526, "rr": 0.42875, "se": 0.526661, "se_clustered": 0.526661, "se_greenland_robins": 0.447049, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Ileus": { "all": { "clustered_wider": true, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 2.93602, "lo": 0.665915, "log_rr": 0.335231, "p": 0.375774, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 1.39826, "se": 0.378488, "se_clustered": 0.378488, "se_greenland_robins": 0.31733, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 4.23439, "lo": 0.522901, "log_rr": 0.397438, "p": 0.456362, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.48801, "se": 0.533582, "se_clustered": 0.533582, "se_greenland_robins": 0.384507, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 3.65938, "lo": 0.402381, "log_rr": 0.193469, "p": 0.731202, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.21345, "se": 0.563186, "se_clustered": 0.46841, "se_greenland_robins": 0.563186, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Impaired gastric emptying": { "all": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 6.48816, "lo": 0.79841, "log_rr": 0.822423, "p": 0.123867, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 2.27601, "se": 0.534477, "se_clustered": 0.534477, "se_greenland_robins": 0.428257, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 11.4644, "lo": 0.788897, "log_rr": 1.10106, "p": 0.106817, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 3.00736, "se": 0.682758, "se_clustered": 0.682758, "se_greenland_robins": 0.577937, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 6.41078, "lo": 0.372881, "log_rr": 0.435742, "p": 0.54818, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.54611, "se": 0.725646, "se_clustered": 0.725646, "se_greenland_robins": 0.656271, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Impaired healing": { "all": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 1.8929, "lo": 0.590335, "log_rr": 0.0555218, "p": 0.851826, "placebo_affected": 22, "placebo_at_risk": 67544, "rr": 1.05709, "se": 0.297244, "se_clustered": 0.196652, "se_greenland_robins": 0.297244, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 3.23639, "lo": 0.665896, "log_rr": 0.383919, "p": 0.341179, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 1.46803, "se": 0.403345, "se_clustered": 0.214362, "se_greenland_robins": 0.403345, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.72805, "lo": 0.289292, "log_rr": -0.346664, "p": 0.447073, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.707043, "se": 0.455955, "se_clustered": 0.239553, "se_greenland_robins": 0.455955, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Incisional hernia": { "all": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 93765, "hi": 1.91087, "lo": 0.685008, "log_rr": 0.134618, "p": 0.606988, "placebo_affected": 27, "placebo_at_risk": 67544, "rr": 1.1441, "se": 0.26171, "se_clustered": 0.190416, "se_greenland_robins": 0.26171, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 2.5564, "lo": 0.597118, "log_rr": 0.211479, "p": 0.568647, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.2355, "se": 0.370986, "se_clustered": 0.182127, "se_greenland_robins": 0.370986, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 2.18761, "lo": 0.513382, "log_rr": 0.0580364, "p": 0.875288, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 1.05975, "se": 0.369788, "se_clustered": 0.348054, "se_greenland_robins": 0.369788, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Infected skin ulcer": { "all": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 2.00576, "lo": 0.294427, "log_rr": -0.263351, "p": 0.590565, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.768472, "se": 0.489485, "se_clustered": 0.489485, "se_greenland_robins": 0.331262, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 2.60809, "lo": 0.13873, "log_rr": -0.508302, "p": 0.497046, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.601516, "se": 0.748443, "se_clustered": 0.748443, "se_greenland_robins": 0.557081, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.861582, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 3.26345, "lo": 0.243968, "log_rr": -0.113967, "p": 0.863237, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.892287, "se": 0.66162, "se_clustered": 0.66162, "se_greenland_robins": 0.414246, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Infection": { "all": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 2.16446, "lo": 0.217564, "log_rr": -0.376546, "p": 0.520567, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.686227, "se": 0.58609, "se_clustered": 0.58609, "se_greenland_robins": 0.455366, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 4.41385, "lo": 0.127563, "log_rr": -0.287198, "p": 0.750734, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.750363, "se": 0.90407, "se_clustered": 0.90407, "se_greenland_robins": 0.540006, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 2.96615, "lo": 0.104975, "log_rr": -0.583383, "p": 0.493716, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 0.558007, "se": 0.852388, "se_clustered": 0.827457, "se_greenland_robins": 0.852388, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Infective exacerbation of chronic obstructive airways disease": { "all": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 1.93049, "lo": 0.47312, "log_rr": -0.0453155, "p": 0.899476, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.955696, "se": 0.358726, "se_clustered": 0.311863, "se_greenland_robins": 0.358726, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 4.60222, "lo": 0.414287, "log_rr": 0.322672, "p": 0.599355, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.38081, "se": 0.614229, "se_clustered": 0.614229, "se_greenland_robins": 0.539767, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.912293, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.83969, "lo": 0.266769, "log_rr": -0.355889, "p": 0.470009, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.700551, "se": 0.492603, "se_clustered": 0.317008, "se_greenland_robins": 0.492603, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Influenza": { "all": { "clustered_wider": false, "glp1_affected": 48, "glp1_at_risk": 93765, "hi": 1.46323, "lo": 0.636656, "log_rr": -0.0354411, "p": 0.867413, "placebo_affected": 45, "placebo_at_risk": 67544, "rr": 0.96518, "se": 0.212292, "se_clustered": 0.182327, "se_greenland_robins": 0.212292, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 47388, "hi": 1.70639, "lo": 0.591733, "log_rr": 0.00483947, "p": 0.985709, "placebo_affected": 27, "placebo_at_risk": 35018, "rr": 1.00485, "se": 0.270178, "se_clustered": 0.24342, "se_greenland_robins": 0.270178, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 1.77582, "lo": 0.462113, "log_rr": -0.0988422, "p": 0.773491, "placebo_affected": 18, "placebo_at_risk": 32526, "rr": 0.905886, "se": 0.343426, "se_clustered": 0.268427, "se_greenland_robins": 0.343426, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Inguinal hernia": { "all": { "clustered_wider": false, "glp1_affected": 142, "glp1_at_risk": 93765, "hi": 1.98999, "lo": 1.17209, "log_rr": 0.42346, "p": 0.00171348, "placebo_affected": 86, "placebo_at_risk": 67544, "rr": 1.52724, "se": 0.135038, "se_clustered": 0.0992453, "se_greenland_robins": 0.135038, "strata_with_events": 26, "trials": 234, "trials_with_events": 26 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 90, "glp1_at_risk": 47388, "hi": 2.15064, "lo": 1.11161, "log_rr": 0.435787, "p": 0.0096413, "placebo_affected": 58, "placebo_at_risk": 35018, "rr": 1.54618, "se": 0.168359, "se_clustered": 0.131827, "se_greenland_robins": 0.168359, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.319394, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 52, "glp1_at_risk": 46377, "hi": 2.32396, "lo": 0.958228, "log_rr": 0.400301, "p": 0.0765327, "placebo_affected": 28, "placebo_at_risk": 32526, "rr": 1.49227, "se": 0.22601, "se_clustered": 0.160404, "se_greenland_robins": 0.22601, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 } }, "Intermittent claudication": { "all": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 93765, "hi": 1.75276, "lo": 0.613004, "log_rr": 0.0359033, "p": 0.893432, "placebo_affected": 27, "placebo_at_risk": 67544, "rr": 1.03656, "se": 0.268008, "se_clustered": 0.205452, "se_greenland_robins": 0.268008, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 47388, "hi": 2.13882, "lo": 0.626957, "log_rr": 0.146689, "p": 0.639369, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 1.15799, "se": 0.31305, "se_clustered": 0.23981, "se_greenland_robins": 0.31305, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 2.13456, "lo": 0.270365, "log_rr": -0.274862, "p": 0.602054, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.759677, "se": 0.527112, "se_clustered": 0.447308, "se_greenland_robins": 0.527112, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Interstitial lung disease": { "all": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 2.77341, "lo": 0.755604, "log_rr": 0.369919, "p": 0.264783, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.44762, "se": 0.331719, "se_clustered": 0.220898, "se_greenland_robins": 0.331719, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 4.10538, "lo": 0.37228, "log_rr": 0.212094, "p": 0.729076, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 1.23626, "se": 0.61236, "se_clustered": 0.489863, "se_greenland_robins": 0.61236, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 3.36353, "lo": 0.714193, "log_rr": 0.438194, "p": 0.267656, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.54991, "se": 0.395311, "se_clustered": 0.222166, "se_greenland_robins": 0.395311, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Intervertebral disc degeneration": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 1.39703, "lo": 0.351969, "log_rr": -0.354932, "p": 0.312857, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 0.701221, "se": 0.351681, "se_clustered": 0.24509, "se_greenland_robins": 0.351681, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 2.21569, "lo": 0.366257, "log_rr": -0.104428, "p": 0.820097, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.900839, "se": 0.459187, "se_clustered": 0.188373, "se_greenland_robins": 0.459187, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.942654, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 1.50114, "lo": 0.167512, "log_rr": -0.690239, "p": 0.217269, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.501456, "se": 0.559431, "se_clustered": 0.522099, "se_greenland_robins": 0.559431, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Intervertebral disc disorder": { "all": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 4.16939, "lo": 0.799198, "log_rr": 0.601811, "p": 0.153271, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.82542, "se": 0.421415, "se_clustered": 0.30119, "se_greenland_robins": 0.421415, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 18.665, "lo": 0.397612, "log_rr": 1.00219, "p": 0.307409, "placebo_affected": 2, "placebo_at_risk": 35018, "rr": 2.72423, "se": 0.981888, "se_clustered": 0.981888, "se_greenland_robins": 0.847997, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.827638, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 4.09384, "lo": 0.600776, "log_rr": 0.449975, "p": 0.358015, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.56827, "se": 0.489554, "se_clustered": 0.25253, "se_greenland_robins": 0.489554, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Intervertebral disc protrusion": { "all": { "clustered_wider": true, "glp1_affected": 123, "glp1_at_risk": 93765, "hi": 1.35266, "lo": 0.719163, "log_rr": -0.0137964, "p": 0.93178, "placebo_affected": 107, "placebo_at_risk": 67544, "rr": 0.986298, "se": 0.161162, "se_clustered": 0.161162, "se_greenland_robins": 0.133391, "strata_with_events": 39, "trials": 234, "trials_with_events": 38 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 70, "glp1_at_risk": 47388, "hi": 2.05667, "lo": 0.660749, "log_rr": 0.153353, "p": 0.596519, "placebo_affected": 53, "placebo_at_risk": 35018, "rr": 1.16574, "se": 0.289665, "se_clustered": 0.289665, "se_greenland_robins": 0.186815, "strata_with_events": 20, "trials": 117, "trials_with_events": 19 }, "discovery_q": 0.911436, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 53, "glp1_at_risk": 46377, "hi": 1.19358, "lo": 0.562506, "log_rr": -0.1992, "p": 0.299297, "placebo_affected": 54, "placebo_at_risk": 32526, "rr": 0.819386, "se": 0.191918, "se_clustered": 0.124524, "se_greenland_robins": 0.191918, "strata_with_events": 19, "trials": 117, "trials_with_events": 19 } }, "Intestinal ischaemia": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 5.2672, "lo": 1.01408, "log_rr": 0.837741, "p": 0.046236, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 2.31114, "se": 0.420293, "se_clustered": 0.420293, "se_greenland_robins": 0.403839, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 4.45168, "lo": 0.641701, "log_rr": 0.524824, "p": 0.288173, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.69016, "se": 0.49412, "se_clustered": 0.49412, "se_greenland_robins": 0.448768, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.824414, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 62.3708, "lo": 0.849295, "log_rr": 1.98487, "p": 0.0701516, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 7.27813, "se": 1.09605, "se_clustered": 0.930043, "se_greenland_robins": 1.09605, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Intestinal obstruction": { "all": { "clustered_wider": false, "glp1_affected": 44, "glp1_at_risk": 93765, "hi": 1.38324, "lo": 0.607285, "log_rr": -0.087164, "p": 0.678094, "placebo_affected": 45, "placebo_at_risk": 67544, "rr": 0.916527, "se": 0.210001, "se_clustered": 0.198664, "se_greenland_robins": 0.210001, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 47388, "hi": 1.61281, "lo": 0.503623, "log_rr": -0.103974, "p": 0.726208, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 0.901249, "se": 0.296921, "se_clustered": 0.296921, "se_greenland_robins": 0.28916, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 46377, "hi": 1.69968, "lo": 0.513179, "log_rr": -0.0683454, "p": 0.822982, "placebo_affected": 21, "placebo_at_risk": 32526, "rr": 0.933938, "se": 0.305508, "se_clustered": 0.287212, "se_greenland_robins": 0.305508, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Intracranial aneurysm": { "all": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.72304, "lo": 0.404631, "log_rr": 0.0484837, "p": 0.920594, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.04968, "se": 0.486368, "se_clustered": 0.486368, "se_greenland_robins": 0.423548, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 8.36556, "lo": 0.119722, "log_rr": 0.00076973, "p": 0.999433, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 1.00077, "se": 1.08336, "se_clustered": 1.08336, "se_greenland_robins": 0.632104, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 3.33766, "lo": 0.356264, "log_rr": 0.0865937, "p": 0.879411, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.09045, "se": 0.570764, "se_clustered": 0.349633, "se_greenland_robins": 0.570764, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Intraductal proliferative breast lesion": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 1.29656, "lo": 0.288006, "log_rr": -0.49253, "p": 0.199393, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.611079, "se": 0.383804, "se_clustered": 0.263874, "se_greenland_robins": 0.383804, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 2.1789, "lo": 0.324372, "log_rr": -0.173522, "p": 0.721005, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.840699, "se": 0.485897, "se_clustered": 0.254912, "se_greenland_robins": 0.485897, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.25782, "lo": 0.0919939, "log_rr": -1.07833, "p": 0.106056, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.340164, "se": 0.667209, "se_clustered": 0.650554, "se_greenland_robins": 0.667209, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Invasive ductal breast carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 54, "glp1_at_risk": 93765, "hi": 1.71443, "lo": 0.748289, "log_rr": 0.124556, "p": 0.555906, "placebo_affected": 41, "placebo_at_risk": 67544, "rr": 1.13265, "se": 0.211495, "se_clustered": 0.163378, "se_greenland_robins": 0.211495, "strata_with_events": 24, "trials": 234, "trials_with_events": 24 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 33, "glp1_at_risk": 47388, "hi": 2.12251, "lo": 0.725272, "log_rr": 0.215696, "p": 0.431051, "placebo_affected": 23, "placebo_at_risk": 35018, "rr": 1.24072, "se": 0.273936, "se_clustered": 0.102863, "se_greenland_robins": 0.273936, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 46377, "hi": 1.90837, "lo": 0.515319, "log_rr": -0.00835921, "p": 0.980032, "placebo_affected": 18, "placebo_at_risk": 32526, "rr": 0.991676, "se": 0.333991, "se_clustered": 0.329403, "se_greenland_robins": 0.333991, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Iron deficiency anaemia": { "all": { "clustered_wider": true, "glp1_affected": 62, "glp1_at_risk": 93765, "hi": 1.66215, "lo": 0.645437, "log_rr": 0.0351412, "p": 0.884218, "placebo_affected": 58, "placebo_at_risk": 67544, "rr": 1.03577, "se": 0.241315, "se_clustered": 0.241315, "se_greenland_robins": 0.182876, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 47388, "hi": 1.26655, "lo": 0.470421, "log_rr": -0.258914, "p": 0.305489, "placebo_affected": 36, "placebo_at_risk": 35018, "rr": 0.771889, "se": 0.252665, "se_clustered": 0.194948, "se_greenland_robins": 0.252665, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.827638, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 2.84026, "lo": 0.745288, "log_rr": 0.374956, "p": 0.271942, "placebo_affected": 22, "placebo_at_risk": 32526, "rr": 1.45493, "se": 0.341302, "se_clustered": 0.341302, "se_greenland_robins": 0.272145, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Ischaemic cardiomyopathy": { "all": { "clustered_wider": true, "glp1_affected": 34, "glp1_at_risk": 93765, "hi": 2.5935, "lo": 0.518591, "log_rr": 0.148184, "p": 0.718199, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 1.15973, "se": 0.410632, "se_clustered": 0.410632, "se_greenland_robins": 0.251052, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 47388, "hi": 2.86365, "lo": 0.42266, "log_rr": 0.0954543, "p": 0.84495, "placebo_affected": 20, "placebo_at_risk": 35018, "rr": 1.10016, "se": 0.488091, "se_clustered": 0.488091, "se_greenland_robins": 0.308846, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.956127, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 6.2596, "lo": 0.264802, "log_rr": 0.252672, "p": 0.754167, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 1.28746, "se": 0.806874, "se_clustered": 0.806874, "se_greenland_robins": 0.431886, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Ischaemic cerebral infarction": { "all": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 93765, "hi": 0.968657, "lo": 0.160743, "log_rr": -0.929896, "p": 0.0424111, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.394595, "se": 0.458198, "se_clustered": 0.294112, "se_greenland_robins": 0.458198, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 0.963688, "lo": 0.106574, "log_rr": -1.13795, "p": 0.0427843, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.320475, "se": 0.561727, "se_clustered": 0.31683, "se_greenland_robins": 0.561727, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.512034, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 3.1288, "lo": 0.125224, "log_rr": -0.468501, "p": 0.568244, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 0.62594, "se": 0.821011, "se_clustered": 0.582557, "se_greenland_robins": 0.821011, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Ischaemic stroke": { "all": { "clustered_wider": false, "glp1_affected": 281, "glp1_at_risk": 93765, "hi": 1.04761, "lo": 0.75725, "log_rr": -0.115774, "p": 0.162049, "placebo_affected": 297, "placebo_at_risk": 67544, "rr": 0.890676, "se": 0.0828016, "se_clustered": 0.0664631, "se_greenland_robins": 0.0828016, "strata_with_events": 40, "trials": 234, "trials_with_events": 40 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 217, "glp1_at_risk": 47388, "hi": 1.1716, "lo": 0.805665, "log_rr": -0.0288572, "p": 0.762589, "placebo_affected": 215, "placebo_at_risk": 35018, "rr": 0.971555, "se": 0.0955272, "se_clustered": 0.0459287, "se_greenland_robins": 0.0955272, "strata_with_events": 22, "trials": 117, "trials_with_events": 22 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 64, "glp1_at_risk": 46377, "hi": 0.950087, "lo": 0.491814, "log_rr": -0.380428, "p": 0.0235261, "placebo_affected": 82, "placebo_at_risk": 32526, "rr": 0.683569, "se": 0.167976, "se_clustered": 0.0604666, "se_greenland_robins": 0.167976, "strata_with_events": 18, "trials": 117, "trials_with_events": 18 } }, "Joint dislocation": { "all": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 1.89565, "lo": 0.618577, "log_rr": 0.0796137, "p": 0.780499, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 1.08287, "se": 0.285693, "se_clustered": 0.202412, "se_greenland_robins": 0.285693, "strata_with_events": 19, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.15792, "lo": 0.452412, "log_rr": -0.0120072, "p": 0.975966, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.988065, "se": 0.398555, "se_clustered": 0.354341, "se_greenland_robins": 0.398555, "strata_with_events": 8, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 2.66494, "lo": 0.532863, "log_rr": 0.175346, "p": 0.669373, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 1.19166, "se": 0.410638, "se_clustered": 0.210204, "se_greenland_robins": 0.410638, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Joint injury": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 3.51186, "lo": 0.507664, "log_rr": 0.289105, "p": 0.55791, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.33523, "se": 0.493397, "se_clustered": 0.493397, "se_greenland_robins": 0.37916, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 10.3855, "lo": 1.09761, "log_rr": 1.21677, "p": 0.0338028, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 3.37628, "se": 0.573296, "se_clustered": 0.511951, "se_greenland_robins": 0.573296, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.447371, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 1.18426, "lo": 0.0725851, "log_rr": -1.22694, "p": 0.0849734, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.293189, "se": 0.712288, "se_clustered": 0.601314, "se_greenland_robins": 0.712288, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Lactic acidosis": { "all": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 1.81852, "lo": 0.458769, "log_rr": -0.0905938, "p": 0.796521, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 0.913389, "se": 0.35134, "se_clustered": 0.35134, "se_greenland_robins": 0.330049, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 4.77329, "lo": 0.758908, "log_rr": 0.64358, "p": 0.170097, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.90328, "se": 0.469119, "se_clustered": 0.23895, "se_greenland_robins": 0.469119, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 1.08293, "lo": 0.114062, "log_rr": -1.04567, "p": 0.0685756, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.351456, "se": 0.574165, "se_clustered": 0.574165, "se_greenland_robins": 0.558297, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Lacunar infarction": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 1.48408, "lo": 0.385791, "log_rr": -0.278833, "p": 0.417203, "placebo_affected": 26, "placebo_at_risk": 67544, "rr": 0.756666, "se": 0.343694, "se_clustered": 0.343694, "se_greenland_robins": 0.293149, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 1.98037, "lo": 0.36485, "log_rr": -0.162492, "p": 0.706506, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.850023, "se": 0.431527, "se_clustered": 0.431527, "se_greenland_robins": 0.349803, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.1984, "lo": 0.145997, "log_rr": -0.568217, "p": 0.411457, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.566534, "se": 0.691824, "se_clustered": 0.691824, "se_greenland_robins": 0.544851, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Large intestine polyp": { "all": { "clustered_wider": true, "glp1_affected": 66, "glp1_at_risk": 93765, "hi": 1.32269, "lo": 0.647069, "log_rr": -0.0778177, "p": 0.669637, "placebo_affected": 65, "placebo_at_risk": 67544, "rr": 0.925133, "se": 0.182394, "se_clustered": 0.182394, "se_greenland_robins": 0.178749, "strata_with_events": 26, "trials": 234, "trials_with_events": 26 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 44, "glp1_at_risk": 47388, "hi": 1.72192, "lo": 0.710084, "log_rr": 0.100534, "p": 0.656401, "placebo_affected": 37, "placebo_at_risk": 35018, "rr": 1.10576, "se": 0.225977, "se_clustered": 0.154777, "se_greenland_robins": 0.225977, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 46377, "hi": 1.36117, "lo": 0.345994, "log_rr": -0.376496, "p": 0.281253, "placebo_affected": 28, "placebo_at_risk": 32526, "rr": 0.686262, "se": 0.349413, "se_clustered": 0.349413, "se_greenland_robins": 0.297363, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Laryngeal squamous cell carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.78199, "lo": 0.316322, "log_rr": -0.286632, "p": 0.515728, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.750788, "se": 0.441009, "se_clustered": 0.388286, "se_greenland_robins": 0.441009, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 3.45765, "lo": 0.289619, "log_rr": 0.000699674, "p": 0.999118, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 1.0007, "se": 0.632609, "se_clustered": 0.565115, "se_greenland_robins": 0.632609, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.95471, "lo": 0.167535, "log_rr": -0.558159, "p": 0.373163, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.572262, "se": 0.626747, "se_clustered": 0.39913, "se_greenland_robins": 0.626747, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Left ventricular dysfunction": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 0.967884, "lo": 0.265281, "log_rr": -0.679804, "p": 0.039511, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 0.506716, "se": 0.33019, "se_clustered": 0.297871, "se_greenland_robins": 0.33019, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 0.964093, "lo": 0.203297, "log_rr": -0.814828, "p": 0.0401643, "placebo_affected": 20, "placebo_at_risk": 35018, "rr": 0.442716, "se": 0.397079, "se_clustered": 0.353373, "se_greenland_robins": 0.397079, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.506242, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.80115, "lo": 0.186951, "log_rr": -0.323439, "p": 0.639517, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.723656, "se": 0.690558, "se_clustered": 0.690558, "se_greenland_robins": 0.602273, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Left ventricular failure": { "all": { "clustered_wider": true, "glp1_affected": 36, "glp1_at_risk": 93765, "hi": 1.36857, "lo": 0.464187, "log_rr": -0.22685, "p": 0.410836, "placebo_affected": 44, "placebo_at_risk": 67544, "rr": 0.797041, "se": 0.275831, "se_clustered": 0.275831, "se_greenland_robins": 0.225338, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 0.981361, "lo": 0.2334, "log_rr": -0.736907, "p": 0.0442921, "placebo_affected": 23, "placebo_at_risk": 35018, "rr": 0.478592, "se": 0.366381, "se_clustered": 0.250574, "se_greenland_robins": 0.366381, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.512034, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 25, "glp1_at_risk": 46377, "hi": 2.48479, "lo": 0.523339, "log_rr": 0.131331, "p": 0.741029, "placebo_affected": 21, "placebo_at_risk": 32526, "rr": 1.14035, "se": 0.397383, "se_clustered": 0.397383, "se_greenland_robins": 0.296283, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Limb injury": { "all": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 1.95688, "lo": 0.667837, "log_rr": 0.13382, "p": 0.625593, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 1.14319, "se": 0.274256, "se_clustered": 0.162457, "se_greenland_robins": 0.274256, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 1.86764, "lo": 0.450362, "log_rr": -0.0865143, "p": 0.811552, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.917122, "se": 0.362859, "se_clustered": 0.151211, "se_greenland_robins": 0.362859, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.938926, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 3.5304, "lo": 0.663077, "log_rr": 0.425273, "p": 0.318828, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 1.53001, "se": 0.426608, "se_clustered": 0.292489, "se_greenland_robins": 0.426608, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Lipase increased": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 11.4922, "lo": 1.52791, "log_rr": 1.43279, "p": 0.005378, "placebo_affected": 5, "placebo_at_risk": 67544, "rr": 4.19035, "se": 0.514747, "se_clustered": 0.276046, "se_greenland_robins": 0.514747, "strata_with_events": 11, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 47388, "hi": 9.59967, "lo": 1.26338, "log_rr": 1.24776, "p": 0.0158709, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 3.48253, "se": 0.517341, "se_clustered": 0.265822, "se_greenland_robins": 0.517341, "strata_with_events": 7, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.335688, "replicated": false, "replication": { "glp1_affected": 5, "glp1_at_risk": 46377, "hi": null, "lo": null, "p": null, "placebo_affected": 0, "placebo_at_risk": 32526, "rr": null, "se": null, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Lipoma": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.57507, "lo": 0.303456, "log_rr": -0.36911, "p": 0.379622, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.69135, "se": 0.420114, "se_clustered": 0.40069, "se_greenland_robins": 0.420114, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.4121, "lo": 0.154135, "log_rr": -0.762425, "p": 0.177248, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.466534, "se": 0.565062, "se_clustered": 0.52572, "se_greenland_robins": 0.565062, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 4.6685, "lo": 0.336853, "log_rr": 0.226366, "p": 0.735721, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.25403, "se": 0.670662, "se_clustered": 0.100901, "se_greenland_robins": 0.670662, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Liver abscess": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 4.95613, "lo": 0.807532, "log_rr": 0.693426, "p": 0.134103, "placebo_affected": 7, "placebo_at_risk": 67544, "rr": 2.00056, "se": 0.462865, "se_clustered": 0.45464, "se_greenland_robins": 0.462865, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 5.97932, "lo": 0.512368, "log_rr": 0.559797, "p": 0.371804, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.75032, "se": 0.626802, "se_clustered": 0.475623, "se_greenland_robins": 0.626802, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 13.5423, "lo": 0.402308, "log_rr": 0.847641, "p": 0.344697, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.33413, "se": 0.897046, "se_clustered": 0.897046, "se_greenland_robins": 0.689901, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Lobar pneumonia": { "all": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 1.7201, "lo": 0.516285, "log_rr": -0.059356, "p": 0.846699, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 0.942371, "se": 0.307016, "se_clustered": 0.155083, "se_greenland_robins": 0.307016, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 1.63061, "lo": 0.467938, "log_rr": -0.135234, "p": 0.6711, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 0.873511, "se": 0.318468, "se_clustered": 0.195425, "se_greenland_robins": 0.318468, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.928384, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 28.2649, "lo": 0.193064, "log_rr": 0.848444, "p": 0.50478, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 2.33601, "se": 1.27205, "se_clustered": 0.857494, "se_greenland_robins": 1.27205, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Localised infection": { "all": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 93765, "hi": 1.21611, "lo": 0.510718, "log_rr": -0.238138, "p": 0.281953, "placebo_affected": 43, "placebo_at_risk": 67544, "rr": 0.788094, "se": 0.22133, "se_clustered": 0.1449, "se_greenland_robins": 0.22133, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 1.37846, "lo": 0.39861, "log_rr": -0.299403, "p": 0.34419, "placebo_affected": 22, "placebo_at_risk": 35018, "rr": 0.741261, "se": 0.31652, "se_clustered": 0.249903, "se_greenland_robins": 0.31652, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 46377, "hi": 1.53486, "lo": 0.455542, "log_rr": -0.178914, "p": 0.563691, "placebo_affected": 21, "placebo_at_risk": 32526, "rr": 0.836178, "se": 0.309879, "se_clustered": 0.173576, "se_greenland_robins": 0.309879, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Loss of consciousness": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 1.48745, "lo": 0.446024, "log_rr": -0.205159, "p": 0.504325, "placebo_affected": 23, "placebo_at_risk": 67544, "rr": 0.814518, "se": 0.307262, "se_clustered": 0.302196, "se_greenland_robins": 0.307262, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.47404, "lo": 0.354072, "log_rr": -0.325123, "p": 0.371555, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.722438, "se": 0.36385, "se_clustered": 0.326238, "se_greenland_robins": 0.36385, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 5.36304, "lo": 0.236011, "log_rr": 0.117828, "p": 0.882441, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.12505, "se": 0.796802, "se_clustered": 0.796802, "se_greenland_robins": 0.583011, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Lower gastrointestinal haemorrhage": { "all": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 93765, "hi": 1.2655, "lo": 0.451349, "log_rr": -0.280022, "p": 0.287021, "placebo_affected": 34, "placebo_at_risk": 67544, "rr": 0.755767, "se": 0.263011, "se_clustered": 0.245197, "se_greenland_robins": 0.263011, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.67689, "lo": 0.360769, "log_rr": -0.251287, "p": 0.521456, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.777799, "se": 0.391961, "se_clustered": 0.374153, "se_greenland_robins": 0.391961, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.873608, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 1.47996, "lo": 0.368371, "log_rr": -0.303324, "p": 0.392562, "placebo_affected": 19, "placebo_at_risk": 32526, "rr": 0.73836, "se": 0.354773, "se_clustered": 0.346516, "se_greenland_robins": 0.354773, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Lower limb fracture": { "all": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 1.48318, "lo": 0.462199, "log_rr": -0.188786, "p": 0.525625, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 0.827964, "se": 0.297441, "se_clustered": 0.282894, "se_greenland_robins": 0.297441, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 1.56884, "lo": 0.208477, "log_rr": -0.558795, "p": 0.277787, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.571898, "se": 0.514874, "se_clustered": 0.514874, "se_greenland_robins": 0.503156, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.823781, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 2.13378, "lo": 0.491918, "log_rr": 0.0242272, "p": 0.948395, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 1.02452, "se": 0.374328, "se_clustered": 0.342823, "se_greenland_robins": 0.374328, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Lower respiratory tract infection": { "all": { "clustered_wider": false, "glp1_affected": 47, "glp1_at_risk": 93765, "hi": 1.45092, "lo": 0.647484, "log_rr": -0.0312315, "p": 0.879399, "placebo_affected": 48, "placebo_at_risk": 67544, "rr": 0.969251, "se": 0.205835, "se_clustered": 0.102685, "se_greenland_robins": 0.205835, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 1.87353, "lo": 0.676092, "log_rr": 0.1182, "p": 0.649408, "placebo_affected": 28, "placebo_at_risk": 35018, "rr": 1.12547, "se": 0.260018, "se_clustered": 0.100863, "se_greenland_robins": 0.260018, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 1.48414, "lo": 0.379548, "log_rr": -0.28697, "p": 0.409404, "placebo_affected": 20, "placebo_at_risk": 32526, "rr": 0.750534, "se": 0.347866, "se_clustered": 0.347866, "se_greenland_robins": 0.341237, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Lumbar radiculopathy": { "all": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 2.38344, "lo": 0.597397, "log_rr": 0.176686, "p": 0.6167, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.19326, "se": 0.352996, "se_clustered": 0.30225, "se_greenland_robins": 0.352996, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 3.11431, "lo": 0.53826, "log_rr": 0.258298, "p": 0.564082, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.29472, "se": 0.44782, "se_clustered": 0.370537, "se_greenland_robins": 0.44782, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 3.24052, "lo": 0.339878, "log_rr": 0.0482824, "p": 0.933109, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.04947, "se": 0.575241, "se_clustered": 0.542282, "se_greenland_robins": 0.575241, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Lumbar spinal stenosis": { "all": { "clustered_wider": false, "glp1_affected": 82, "glp1_at_risk": 93765, "hi": 1.23108, "lo": 0.666199, "log_rr": -0.0991388, "p": 0.526819, "placebo_affected": 85, "placebo_at_risk": 67544, "rr": 0.905617, "se": 0.15665, "se_clustered": 0.145343, "se_greenland_robins": 0.15665, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 45, "glp1_at_risk": 47388, "hi": 1.48038, "lo": 0.639257, "log_rr": -0.027576, "p": 0.897576, "placebo_affected": 44, "placebo_at_risk": 35018, "rr": 0.972801, "se": 0.214225, "se_clustered": 0.182369, "se_greenland_robins": 0.214225, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.973628, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 46377, "hi": 1.30918, "lo": 0.531398, "log_rr": -0.181424, "p": 0.43026, "placebo_affected": 41, "placebo_at_risk": 32526, "rr": 0.834082, "se": 0.230015, "se_clustered": 0.207709, "se_greenland_robins": 0.230015, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Lumbar vertebral fracture": { "all": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 2.06537, "lo": 0.566764, "log_rr": 0.0787485, "p": 0.811326, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 1.08193, "se": 0.329884, "se_clustered": 0.230885, "se_greenland_robins": 0.329884, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 2.57471, "lo": 0.452503, "log_rr": 0.0763874, "p": 0.863267, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 1.07938, "se": 0.443553, "se_clustered": 0.279062, "se_greenland_robins": 0.443553, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.959593, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 2.85448, "lo": 0.412508, "log_rr": 0.0816945, "p": 0.868512, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.08512, "se": 0.493476, "se_clustered": 0.417591, "se_greenland_robins": 0.493476, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Lung adenocarcinoma": { "all": { "clustered_wider": false, "glp1_affected": 44, "glp1_at_risk": 93765, "hi": 1.43813, "lo": 0.615494, "log_rr": -0.0609923, "p": 0.778162, "placebo_affected": 44, "placebo_at_risk": 67544, "rr": 0.940831, "se": 0.216503, "se_clustered": 0.187152, "se_greenland_robins": 0.216503, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 33, "glp1_at_risk": 47388, "hi": 2.58706, "lo": 0.847265, "log_rr": 0.39239, "p": 0.168222, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.48051, "se": 0.284766, "se_clustered": 0.132983, "se_greenland_robins": 0.284766, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 0.937738, "lo": 0.220769, "log_rr": -0.787461, "p": 0.0328273, "placebo_affected": 23, "placebo_at_risk": 32526, "rr": 0.454999, "se": 0.368974, "se_clustered": 0.29995, "se_greenland_robins": 0.368974, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Lung cancer metastatic": { "all": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 1.85657, "lo": 0.653487, "log_rr": 0.096649, "p": 0.71673, "placebo_affected": 26, "placebo_at_risk": 67544, "rr": 1.10147, "se": 0.266373, "se_clustered": 0.16221, "se_greenland_robins": 0.266373, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.68564, "lo": 0.568915, "log_rr": 0.211948, "p": 0.592413, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.23608, "se": 0.395911, "se_clustered": 0.341109, "se_greenland_robins": 0.395911, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.911436, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 2.03268, "lo": 0.493855, "log_rr": 0.00192067, "p": 0.995754, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 1.00192, "se": 0.360943, "se_clustered": 0.121752, "se_greenland_robins": 0.360943, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Lung neoplasm malignant": { "all": { "clustered_wider": true, "glp1_affected": 48, "glp1_at_risk": 93765, "hi": 1.49533, "lo": 0.531793, "log_rr": -0.114576, "p": 0.663982, "placebo_affected": 50, "placebo_at_risk": 67544, "rr": 0.891745, "se": 0.263742, "se_clustered": 0.263742, "se_greenland_robins": 0.198392, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 1.47567, "lo": 0.26513, "log_rr": -0.469213, "p": 0.283972, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.625494, "se": 0.437928, "se_clustered": 0.437928, "se_greenland_robins": 0.343273, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.823828, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 1.98645, "lo": 0.585645, "log_rr": 0.0756539, "p": 0.808158, "placebo_affected": 29, "placebo_at_risk": 32526, "rr": 1.07859, "se": 0.311585, "se_clustered": 0.311585, "se_greenland_robins": 0.246143, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Major depression": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 3.03673, "lo": 0.593651, "log_rr": 0.294659, "p": 0.479169, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.34267, "se": 0.416397, "se_clustered": 0.416397, "se_greenland_robins": 0.362076, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 2.75309, "lo": 0.33168, "log_rr": -0.0454305, "p": 0.932938, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.955586, "se": 0.539885, "se_clustered": 0.539885, "se_greenland_robins": 0.4389, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.992086, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 10.9277, "lo": 0.69885, "log_rr": 1.01649, "p": 0.1473, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.76348, "se": 0.701447, "se_clustered": 0.367162, "se_greenland_robins": 0.701447, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Malignant melanoma": { "all": { "clustered_wider": false, "glp1_affected": 47, "glp1_at_risk": 93765, "hi": 1.72148, "lo": 0.722656, "log_rr": 0.10918, "p": 0.62197, "placebo_affected": 38, "placebo_at_risk": 67544, "rr": 1.11536, "se": 0.221434, "se_clustered": 0.0994959, "se_greenland_robins": 0.221434, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 47388, "hi": 2.12534, "lo": 0.672359, "log_rr": 0.178485, "p": 0.543243, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.19541, "se": 0.293601, "se_clustered": 0.137783, "se_greenland_robins": 0.293601, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.889884, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 1.97027, "lo": 0.524089, "log_rr": 0.0160391, "p": 0.962133, "placebo_affected": 17, "placebo_at_risk": 32526, "rr": 1.01617, "se": 0.337829, "se_clustered": 0.159094, "se_greenland_robins": 0.337829, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Mallory-Weiss syndrome": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 21.971, "lo": 1.30743, "log_rr": 1.67889, "p": 0.0196817, "placebo_affected": 3, "placebo_at_risk": 67544, "rr": 5.35961, "se": 0.719825, "se_clustered": 0.719825, "se_greenland_robins": 0.634239, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 125.85, "lo": 1.34413, "log_rr": 2.56542, "p": 0.0267358, "placebo_affected": 1, "placebo_at_risk": 35018, "rr": 13.0061, "se": 1.15802, "se_clustered": 1.15802, "se_greenland_robins": 1.03792, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.414538, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 10.3882, "lo": 0.22629, "log_rr": 0.427365, "p": 0.661541, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 1.53321, "se": 0.976193, "se_clustered": 0.976193, "se_greenland_robins": 0.936606, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Melaena": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.79982, "lo": 0.37562, "log_rr": -0.195745, "p": 0.624341, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.822222, "se": 0.399718, "se_clustered": 0.29234, "se_greenland_robins": 0.399718, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.309, "lo": 0.286571, "log_rr": -0.206477, "p": 0.698093, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.813445, "se": 0.532301, "se_clustered": 0.48134, "se_greenland_robins": 0.532301, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.73094, "lo": 0.254649, "log_rr": -0.181612, "p": 0.764129, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.833925, "se": 0.605245, "se_clustered": 0.316466, "se_greenland_robins": 0.605245, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Meningioma": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.75082, "lo": 0.48982, "log_rr": 0.149092, "p": 0.734852, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.16078, "se": 0.440217, "se_clustered": 0.357618, "se_greenland_robins": 0.440217, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 5.59907, "lo": 0.568243, "log_rr": 0.578697, "p": 0.321422, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.78371, "se": 0.583635, "se_clustered": 0.446052, "se_greenland_robins": 0.583635, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.841898, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 2.67643, "lo": 0.134884, "log_rr": -0.509427, "p": 0.503909, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.60084, "se": 0.762214, "se_clustered": 0.762214, "se_greenland_robins": 0.73, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Meniscus injury": { "all": { "clustered_wider": true, "glp1_affected": 43, "glp1_at_risk": 93765, "hi": 1.58274, "lo": 0.53351, "log_rr": -0.0845603, "p": 0.760505, "placebo_affected": 39, "placebo_at_risk": 67544, "rr": 0.918916, "se": 0.277412, "se_clustered": 0.277412, "se_greenland_robins": 0.218455, "strata_with_events": 25, "trials": 234, "trials_with_events": 25 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 1.63228, "lo": 0.289356, "log_rr": -0.37506, "p": 0.395441, "placebo_affected": 19, "placebo_at_risk": 35018, "rr": 0.687248, "se": 0.441355, "se_clustered": 0.441355, "se_greenland_robins": 0.331203, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 27, "glp1_at_risk": 46377, "hi": 2.28326, "lo": 0.576888, "log_rr": 0.137748, "p": 0.69469, "placebo_affected": 20, "placebo_at_risk": 32526, "rr": 1.14769, "se": 0.350953, "se_clustered": 0.350953, "se_greenland_robins": 0.294754, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Mental status changes": { "all": { "clustered_wider": true, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 3.69647, "lo": 0.492296, "log_rr": 0.299352, "p": 0.560534, "placebo_affected": 23, "placebo_at_risk": 67544, "rr": 1.34898, "se": 0.514309, "se_clustered": 0.514309, "se_greenland_robins": 0.276335, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 47388, "hi": 6.78318, "lo": 0.561075, "log_rr": 0.668272, "p": 0.293236, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 1.95086, "se": 0.635814, "se_clustered": 0.635814, "se_greenland_robins": 0.390493, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.824414, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 4.7378, "lo": 0.165694, "log_rr": -0.12102, "p": 0.887495, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 0.886016, "se": 0.85542, "se_clustered": 0.85542, "se_greenland_robins": 0.406517, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Metabolic acidosis": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.11596, "lo": 0.349257, "log_rr": -0.471117, "p": 0.111892, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 0.624304, "se": 0.296348, "se_clustered": 0.201958, "se_greenland_robins": 0.296348, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.75873, "lo": 0.388529, "log_rr": -0.190399, "p": 0.621109, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.826629, "se": 0.385206, "se_clustered": 0.128162, "se_greenland_robins": 0.385206, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.913084, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.07815, "lo": 0.165173, "log_rr": -0.862756, "p": 0.07143, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 0.421997, "se": 0.478582, "se_clustered": 0.27897, "se_greenland_robins": 0.478582, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Metabolic encephalopathy": { "all": { "clustered_wider": true, "glp1_affected": 36, "glp1_at_risk": 93765, "hi": 2.90342, "lo": 0.729849, "log_rr": 0.375486, "p": 0.286444, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 1.4557, "se": 0.352253, "se_clustered": 0.352253, "se_greenland_robins": 0.258836, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 3.72607, "lo": 0.373898, "log_rr": 0.165791, "p": 0.777431, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 1.18033, "se": 0.586523, "se_clustered": 0.586523, "se_greenland_robins": 0.354679, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 3.90025, "lo": 0.867728, "log_rr": 0.609582, "p": 0.111853, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.83966, "se": 0.383404, "se_clustered": 0.325509, "se_greenland_robins": 0.383404, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Metastases to liver": { "all": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 1.76818, "lo": 0.340218, "log_rr": -0.254108, "p": 0.545593, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 0.775608, "se": 0.420446, "se_clustered": 0.420446, "se_greenland_robins": 0.275385, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 2.47315, "lo": 0.140042, "log_rr": -0.53016, "p": 0.469202, "placebo_affected": 17, "placebo_at_risk": 35018, "rr": 0.588511, "se": 0.73249, "se_clustered": 0.73249, "se_greenland_robins": 0.398469, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 2.22842, "lo": 0.472998, "log_rr": 0.0263138, "p": 0.946941, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.02666, "se": 0.395404, "se_clustered": 0.395404, "se_greenland_robins": 0.387717, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Metastases to lung": { "all": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.38827, "lo": 0.248359, "log_rr": -0.532412, "p": 0.225237, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.587187, "se": 0.439023, "se_clustered": 0.439023, "se_greenland_robins": 0.415995, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 2.55072, "lo": 0.288212, "log_rr": -0.153842, "p": 0.782108, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.857407, "se": 0.556243, "se_clustered": 0.39142, "se_greenland_robins": 0.556243, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 1.46872, "lo": 0.0883243, "log_rr": -1.02117, "p": 0.15446, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.360172, "se": 0.717139, "se_clustered": 0.717139, "se_greenland_robins": 0.659871, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Migraine": { "all": { "clustered_wider": true, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 3.46551, "lo": 0.837379, "log_rr": 0.532691, "p": 0.141521, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.70351, "se": 0.362338, "se_clustered": 0.362338, "se_greenland_robins": 0.31951, "strata_with_events": 17, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 3.12584, "lo": 0.491899, "log_rr": 0.21511, "p": 0.648395, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.24, "se": 0.47174, "se_clustered": 0.47174, "se_greenland_robins": 0.393183, "strata_with_events": 10, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 9.65748, "lo": 0.979994, "log_rr": 1.12376, "p": 0.0541869, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 3.0764, "se": 0.583669, "se_clustered": 0.502948, "se_greenland_robins": 0.583669, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Mitral valve incompetence": { "all": { "clustered_wider": true, "glp1_affected": 28, "glp1_at_risk": 93765, "hi": 1.50167, "lo": 0.404185, "log_rr": -0.249651, "p": 0.455889, "placebo_affected": 34, "placebo_at_risk": 67544, "rr": 0.779072, "se": 0.334818, "se_clustered": 0.334818, "se_greenland_robins": 0.256129, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 0.790477, "lo": 0.173142, "log_rr": -0.994381, "p": 0.0102612, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 0.369953, "se": 0.387386, "se_clustered": 0.297546, "se_greenland_robins": 0.387386, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.319394, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 3.75647, "lo": 0.808891, "log_rr": 0.555694, "p": 0.156031, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.74315, "se": 0.391734, "se_clustered": 0.281689, "se_greenland_robins": 0.391734, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Multiple injuries": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.30902, "lo": 0.426229, "log_rr": -0.00797764, "p": 0.985233, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.992054, "se": 0.431029, "se_clustered": 0.323639, "se_greenland_robins": 0.431029, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.43575, "lo": 0.264833, "log_rr": -0.2192, "p": 0.698579, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.803161, "se": 0.56606, "se_clustered": 0.388547, "se_greenland_robins": 0.56606, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 5.02978, "lo": 0.353425, "log_rr": 0.287647, "p": 0.671116, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.33329, "se": 0.677425, "se_clustered": 0.604178, "se_greenland_robins": 0.677425, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Multiple organ dysfunction syndrome": { "all": { "clustered_wider": true, "glp1_affected": 41, "glp1_at_risk": 93765, "hi": 1.17686, "lo": 0.508626, "log_rr": -0.256597, "p": 0.230521, "placebo_affected": 53, "placebo_at_risk": 67544, "rr": 0.77368, "se": 0.214006, "se_clustered": 0.214006, "se_greenland_robins": 0.207792, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 25, "glp1_at_risk": 47388, "hi": 1.54999, "lo": 0.419764, "log_rr": -0.214905, "p": 0.519006, "placebo_affected": 31, "placebo_at_risk": 35018, "rr": 0.806618, "se": 0.333249, "se_clustered": 0.333249, "se_greenland_robins": 0.26857, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.872335, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 1.38386, "lo": 0.38221, "log_rr": -0.318454, "p": 0.331947, "placebo_affected": 22, "placebo_at_risk": 32526, "rr": 0.727272, "se": 0.328236, "se_clustered": 0.272124, "se_greenland_robins": 0.328236, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Muscular weakness": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 1.9081, "lo": 0.446356, "log_rr": -0.0802664, "p": 0.828534, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 0.92287, "se": 0.370605, "se_clustered": 0.370605, "se_greenland_robins": 0.347824, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 3.54432, "lo": 0.282192, "log_rr": 8.95887e-05, "p": 0.999889, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.00009, "se": 0.645551, "se_clustered": 0.645551, "se_greenland_robins": 0.499884, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 2.21619, "lo": 0.331147, "log_rr": -0.154701, "p": 0.749725, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.856671, "se": 0.484954, "se_clustered": 0.462569, "se_greenland_robins": 0.484954, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Musculoskeletal chest pain": { "all": { "clustered_wider": false, "glp1_affected": 60, "glp1_at_risk": 93765, "hi": 1.39242, "lo": 0.675196, "log_rr": -0.0308546, "p": 0.867289, "placebo_affected": 59, "placebo_at_risk": 67544, "rr": 0.969617, "se": 0.184645, "se_clustered": 0.168001, "se_greenland_robins": 0.184645, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 47388, "hi": 1.41184, "lo": 0.511776, "log_rr": -0.162487, "p": 0.530219, "placebo_affected": 32, "placebo_at_risk": 35018, "rr": 0.850027, "se": 0.258873, "se_clustered": 0.114116, "se_greenland_robins": 0.258873, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.87972, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 32, "glp1_at_risk": 46377, "hi": 2.04775, "lo": 0.602883, "log_rr": 0.105354, "p": 0.735558, "placebo_affected": 27, "placebo_at_risk": 32526, "rr": 1.1111, "se": 0.311938, "se_clustered": 0.311938, "se_greenland_robins": 0.264642, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Musculoskeletal pain": { "all": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 2.31831, "lo": 0.658107, "log_rr": 0.211225, "p": 0.510836, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 1.23519, "se": 0.321237, "se_clustered": 0.315314, "se_greenland_robins": 0.321237, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 6.14533, "lo": 0.886592, "log_rr": 0.847661, "p": 0.0861163, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 2.33418, "se": 0.493903, "se_clustered": 0.0886727, "se_greenland_robins": 0.493903, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.625859, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.68733, "lo": 0.279208, "log_rr": -0.376325, "p": 0.412207, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.686379, "se": 0.458924, "se_clustered": 0.359569, "se_greenland_robins": 0.458924, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Myocardial infarction": { "all": { "clustered_wider": false, "glp1_affected": 265, "glp1_at_risk": 93765, "hi": 1.03162, "lo": 0.732632, "log_rr": -0.139989, "p": 0.108855, "placebo_affected": 271, "placebo_at_risk": 67544, "rr": 0.869368, "se": 0.0873094, "se_clustered": 0.0542154, "se_greenland_robins": 0.0873094, "strata_with_events": 47, "trials": 234, "trials_with_events": 47 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 173, "glp1_at_risk": 47388, "hi": 1.13309, "lo": 0.742535, "log_rr": -0.0863664, "p": 0.423107, "placebo_affected": 178, "placebo_at_risk": 35018, "rr": 0.917258, "se": 0.107818, "se_clustered": 0.07714, "se_greenland_robins": 0.107818, "strata_with_events": 20, "trials": 117, "trials_with_events": 20 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 92, "glp1_at_risk": 46377, "hi": 1.04953, "lo": 0.585009, "log_rr": -0.243894, "p": 0.101889, "placebo_affected": 93, "placebo_at_risk": 32526, "rr": 0.78357, "se": 0.149101, "se_clustered": 0.0916677, "se_greenland_robins": 0.149101, "strata_with_events": 27, "trials": 117, "trials_with_events": 27 } }, "Myocardial ischaemia": { "all": { "clustered_wider": false, "glp1_affected": 130, "glp1_at_risk": 93765, "hi": 0.940264, "lo": 0.592785, "log_rr": -0.292259, "p": 0.0130159, "placebo_affected": 164, "placebo_at_risk": 67544, "rr": 0.746575, "se": 0.117688, "se_clustered": 0.11449, "se_greenland_robins": 0.117688, "strata_with_events": 24, "trials": 234, "trials_with_events": 24 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 79, "glp1_at_risk": 47388, "hi": 0.860699, "lo": 0.487505, "log_rr": -0.434233, "p": 0.00274972, "placebo_affected": 119, "placebo_at_risk": 35018, "rr": 0.647761, "se": 0.145014, "se_clustered": 0.103913, "se_greenland_robins": 0.145014, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.157651, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 51, "glp1_at_risk": 46377, "hi": 1.52713, "lo": 0.652116, "log_rr": -0.00206962, "p": 0.992393, "placebo_affected": 45, "placebo_at_risk": 32526, "rr": 0.997933, "se": 0.217077, "se_clustered": 0.217077, "se_greenland_robins": 0.204452, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Nausea": { "all": { "clustered_wider": false, "glp1_affected": 66, "glp1_at_risk": 93765, "hi": 2.92182, "lo": 1.17027, "log_rr": 0.61472, "p": 0.00844881, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 1.84914, "se": 0.233415, "se_clustered": 0.228825, "se_greenland_robins": 0.233415, "strata_with_events": 31, "trials": 234, "trials_with_events": 30 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 39, "glp1_at_risk": 47388, "hi": 2.3246, "lo": 0.813446, "log_rr": 0.318535, "p": 0.23438, "placebo_affected": 25, "placebo_at_risk": 35018, "rr": 1.37511, "se": 0.267868, "se_clustered": 0.199426, "se_greenland_robins": 0.267868, "strata_with_events": 17, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 46377, "hi": 11.7919, "lo": 1.50971, "log_rr": 1.43967, "p": 0.00604175, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 4.21929, "se": 0.524372, "se_clustered": 0.457772, "se_greenland_robins": 0.524372, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Neck pain": { "all": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 93765, "hi": 1.11725, "lo": 0.122616, "log_rr": -0.993911, "p": 0.0778558, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.370126, "se": 0.563676, "se_clustered": 0.563676, "se_greenland_robins": 0.512251, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.28526, "lo": 0.0878495, "log_rr": -1.09058, "p": 0.11109, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.33602, "se": 0.684475, "se_clustered": 0.684475, "se_greenland_robins": 0.593416, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 5.43183, "lo": 0.0458442, "log_rr": -0.695115, "p": 0.568226, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 0.499017, "se": 1.21808, "se_clustered": 1.21808, "se_greenland_robins": 1.02896, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Nephrolithiasis": { "all": { "clustered_wider": false, "glp1_affected": 179, "glp1_at_risk": 93765, "hi": 1.45394, "lo": 0.924386, "log_rr": 0.147827, "p": 0.200738, "placebo_affected": 133, "placebo_at_risk": 67544, "rr": 1.15931, "se": 0.115539, "se_clustered": 0.0771324, "se_greenland_robins": 0.115539, "strata_with_events": 53, "trials": 234, "trials_with_events": 50 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 109, "glp1_at_risk": 47388, "hi": 1.60739, "lo": 0.895555, "log_rr": 0.18215, "p": 0.222201, "placebo_affected": 80, "placebo_at_risk": 35018, "rr": 1.19979, "se": 0.149218, "se_clustered": 0.100924, "se_greenland_robins": 0.149218, "strata_with_events": 28, "trials": 117, "trials_with_events": 26 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 70, "glp1_at_risk": 46377, "hi": 1.57367, "lo": 0.76905, "log_rr": 0.0954068, "p": 0.601447, "placebo_affected": 53, "placebo_at_risk": 32526, "rr": 1.10011, "se": 0.18266, "se_clustered": 0.119578, "se_greenland_robins": 0.18266, "strata_with_events": 25, "trials": 117, "trials_with_events": 24 } }, "Nephropathy": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.1615, "lo": 0.281396, "log_rr": -0.559138, "p": 0.122103, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 0.571701, "se": 0.361667, "se_clustered": 0.271018, "se_greenland_robins": 0.361667, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 1.4854, "lo": 0.278598, "log_rr": -0.44115, "p": 0.3015, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 0.643296, "se": 0.426965, "se_clustered": 0.424778, "se_greenland_robins": 0.426965, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.82752, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 1.65656, "lo": 0.110871, "log_rr": -0.84732, "p": 0.219341, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.428562, "se": 0.689842, "se_clustered": 0.509724, "se_greenland_robins": 0.689842, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Neuropathy peripheral": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 2.63127, "lo": 0.568658, "log_rr": 0.201495, "p": 0.606145, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.22323, "se": 0.390809, "se_clustered": 0.382565, "se_greenland_robins": 0.390809, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 3.06646, "lo": 0.226588, "log_rr": -0.182049, "p": 0.784141, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.83356, "se": 0.66459, "se_clustered": 0.66459, "se_greenland_robins": 0.605424, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 4.49957, "lo": 0.578351, "log_rr": 0.478203, "p": 0.36087, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.61317, "se": 0.523366, "se_clustered": 0.510438, "se_greenland_robins": 0.523366, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Non-Hodgkin's lymphoma": { "all": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.92178, "lo": 0.319445, "log_rr": -0.243959, "p": 0.594082, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.78352, "se": 0.457769, "se_clustered": 0.388123, "se_greenland_robins": 0.457769, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 2.59455, "lo": 0.196816, "log_rr": -0.336036, "p": 0.609508, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.714597, "se": 0.657894, "se_clustered": 0.657894, "se_greenland_robins": 0.585419, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 3.83729, "lo": 0.213112, "log_rr": -0.100586, "p": 0.891506, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 0.904308, "se": 0.737438, "se_clustered": 0.31695, "se_greenland_robins": 0.737438, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Non-cardiac chest pain": { "all": { "clustered_wider": true, "glp1_affected": 417, "glp1_at_risk": 93765, "hi": 1.1203, "lo": 0.817698, "log_rr": -0.0438332, "p": 0.585262, "placebo_affected": 414, "placebo_at_risk": 67544, "rr": 0.957114, "se": 0.0803225, "se_clustered": 0.0803225, "se_greenland_robins": 0.069826, "strata_with_events": 42, "trials": 234, "trials_with_events": 41 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 246, "glp1_at_risk": 47388, "hi": 1.1737, "lo": 0.767255, "log_rr": -0.0523865, "p": 0.629049, "placebo_affected": 249, "placebo_at_risk": 35018, "rr": 0.948962, "se": 0.108446, "se_clustered": 0.108446, "se_greenland_robins": 0.0900144, "strata_with_events": 23, "trials": 117, "trials_with_events": 22 }, "discovery_q": 0.916918, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 171, "glp1_at_risk": 46377, "hi": 1.21893, "lo": 0.770986, "log_rr": -0.0310567, "p": 0.790413, "placebo_affected": 165, "placebo_at_risk": 32526, "rr": 0.969421, "se": 0.116854, "se_clustered": 0.116854, "se_greenland_robins": 0.110645, "strata_with_events": 19, "trials": 117, "trials_with_events": 19 } }, "Non-small cell lung cancer": { "all": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 2.98872, "lo": 0.435099, "log_rr": 0.131332, "p": 0.789351, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.14035, "se": 0.491598, "se_clustered": 0.491598, "se_greenland_robins": 0.397354, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 5.60342, "lo": 0.564865, "log_rr": 0.576105, "p": 0.325018, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.77909, "se": 0.585354, "se_clustered": 0.585354, "se_greenland_robins": 0.513818, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.842691, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 3.85988, "lo": 0.0651443, "log_rr": -0.690258, "p": 0.507403, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.501447, "se": 1.04129, "se_clustered": 1.04129, "se_greenland_robins": 0.706719, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Obesity": { "all": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 0.716329, "lo": 0.174845, "log_rr": -1.03873, "p": 0.00388574, "placebo_affected": 47, "placebo_at_risk": 67544, "rr": 0.353902, "se": 0.359761, "se_clustered": 0.359761, "se_greenland_robins": 0.264578, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 0.9806, "lo": 0.10857, "log_rr": -1.11998, "p": 0.0460584, "placebo_affected": 25, "placebo_at_risk": 35018, "rr": 0.326287, "se": 0.561432, "se_clustered": 0.561432, "se_greenland_robins": 0.356765, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.516656, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.05504, "lo": 0.142813, "log_rr": -0.94632, "p": 0.0636041, "placebo_affected": 22, "placebo_at_risk": 32526, "rr": 0.388167, "se": 0.510161, "se_clustered": 0.510161, "se_greenland_robins": 0.39464, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Obstructive pancreatitis": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 1.32743, "lo": 0.380874, "log_rr": -0.341021, "p": 0.284312, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 0.711044, "se": 0.318508, "se_clustered": 0.274797, "se_greenland_robins": 0.318508, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.44739, "lo": 0.34833, "log_rr": -0.34242, "p": 0.346011, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.71005, "se": 0.363366, "se_clustered": 0.323419, "se_greenland_robins": 0.363366, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.60367, "lo": 0.195842, "log_rr": -0.336762, "p": 0.609909, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.714079, "se": 0.660055, "se_clustered": 0.598875, "se_greenland_robins": 0.660055, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Oedema peripheral": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 0.871762, "lo": 0.294791, "log_rr": -0.679364, "p": 0.0140444, "placebo_affected": 38, "placebo_at_risk": 67544, "rr": 0.506939, "se": 0.2766, "se_clustered": 0.190455, "se_greenland_robins": 0.2766, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.1479, "lo": 0.263734, "log_rr": -0.597439, "p": 0.111311, "placebo_affected": 20, "placebo_at_risk": 35018, "rr": 0.550219, "se": 0.375199, "se_clustered": 0.328299, "se_greenland_robins": 0.375199, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 1.02823, "lo": 0.20591, "log_rr": -0.776236, "p": 0.0584782, "placebo_affected": 18, "placebo_at_risk": 32526, "rr": 0.460135, "se": 0.410252, "se_clustered": 0.185443, "se_greenland_robins": 0.410252, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Oesophageal adenocarcinoma": { "all": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 2.38825, "lo": 0.291262, "log_rr": -0.181487, "p": 0.735281, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.834029, "se": 0.536768, "se_clustered": 0.536768, "se_greenland_robins": 0.428129, "strata_with_events": 5, "trials": 234, "trials_with_events": 5 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 5.74711, "lo": 0.174025, "log_rr": 6.9926e-05, "p": 0.999937, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.00007, "se": 0.892173, "se_clustered": 0.892173, "se_greenland_robins": 0.534426, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 2.51554, "lo": 0.143731, "log_rr": -0.508662, "p": 0.486045, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.6013, "se": 0.730193, "se_clustered": 0.132135, "se_greenland_robins": 0.730193, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Oesophageal carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 1.91657, "lo": 0.414001, "log_rr": -0.115675, "p": 0.767311, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.890765, "se": 0.390932, "se_clustered": 0.232351, "se_greenland_robins": 0.390932, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 5.82913, "lo": 0.476223, "log_rr": 0.5105, "p": 0.424328, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.66612, "se": 0.638975, "se_clustered": 0.408161, "se_greenland_robins": 0.638975, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 1.58658, "lo": 0.204564, "log_rr": -0.562645, "p": 0.281624, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.5697, "se": 0.522575, "se_clustered": 0.371859, "se_greenland_robins": 0.522575, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Oesophagitis": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.08256, "lo": 0.432556, "log_rr": -0.0522223, "p": 0.896368, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.949118, "se": 0.400936, "se_clustered": 0.217321, "se_greenland_robins": 0.400936, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 3.07402, "lo": 0.390127, "log_rr": 0.0908528, "p": 0.863025, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.09511, "se": 0.526609, "se_clustered": 0.300383, "se_greenland_robins": 0.526609, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.959593, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 2.64345, "lo": 0.229351, "log_rr": -0.250207, "p": 0.688265, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.77864, "se": 0.62363, "se_clustered": 0.277314, "se_greenland_robins": 0.62363, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Orchitis": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.02298, "lo": 0.421432, "log_rr": -0.0797633, "p": 0.842012, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.923335, "se": 0.400177, "se_clustered": 0.245062, "se_greenland_robins": 0.400177, "strata_with_events": 5, "trials": 234, "trials_with_events": 5 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 2.30348, "lo": 0.343116, "log_rr": -0.117633, "p": 0.808651, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.889022, "se": 0.485751, "se_clustered": 0.339385, "se_greenland_robins": 0.485751, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.937672, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 3.99838, "lo": 0.250375, "log_rr": 0.000545844, "p": 0.999384, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.00055, "se": 0.706821, "se_clustered": 0.500778, "se_greenland_robins": 0.706821, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Orthostatic hypotension": { "all": { "clustered_wider": false, "glp1_affected": 64, "glp1_at_risk": 93765, "hi": 1.89255, "lo": 0.878161, "log_rr": 0.253999, "p": 0.194739, "placebo_affected": 47, "placebo_at_risk": 67544, "rr": 1.28917, "se": 0.195883, "se_clustered": 0.122402, "se_greenland_robins": 0.195883, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 44, "glp1_at_risk": 47388, "hi": 2.08144, "lo": 0.824216, "log_rr": 0.269868, "p": 0.253482, "placebo_affected": 32, "placebo_at_risk": 35018, "rr": 1.30979, "se": 0.236326, "se_clustered": 0.143514, "se_greenland_robins": 0.236326, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 46377, "hi": 2.47363, "lo": 0.626799, "log_rr": 0.219278, "p": 0.531233, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 1.24518, "se": 0.350214, "se_clustered": 0.239875, "se_greenland_robins": 0.350214, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Osteoarthritis": { "all": { "clustered_wider": true, "glp1_affected": 518, "glp1_at_risk": 93765, "hi": 1.14296, "lo": 0.822528, "log_rr": -0.0308736, "p": 0.712984, "placebo_affected": 492, "placebo_at_risk": 67544, "rr": 0.969598, "se": 0.0839298, "se_clustered": 0.0839298, "se_greenland_robins": 0.0629183, "strata_with_events": 63, "trials": 234, "trials_with_events": 63 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 252, "glp1_at_risk": 47388, "hi": 1.20252, "lo": 0.802032, "log_rr": -0.0180918, "p": 0.861005, "placebo_affected": 236, "placebo_at_risk": 35018, "rr": 0.982071, "se": 0.103326, "se_clustered": 0.103326, "se_greenland_robins": 0.0909605, "strata_with_events": 34, "trials": 117, "trials_with_events": 34 }, "discovery_q": 0.959593, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 266, "glp1_at_risk": 46377, "hi": 1.24974, "lo": 0.734591, "log_rr": -0.0427516, "p": 0.752478, "placebo_affected": 256, "placebo_at_risk": 32526, "rr": 0.958149, "se": 0.135559, "se_clustered": 0.135559, "se_greenland_robins": 0.0871231, "strata_with_events": 29, "trials": 117, "trials_with_events": 29 } }, "Osteochondrosis": { "all": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 2.01557, "lo": 0.304884, "log_rr": -0.24346, "p": 0.613359, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.783911, "se": 0.481827, "se_clustered": 0.481827, "se_greenland_robins": 0.412615, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.62161, "lo": 0.174073, "log_rr": -0.632432, "p": 0.266632, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.531298, "se": 0.569321, "se_clustered": 0.239394, "se_greenland_robins": 0.569321, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 8.63255, "lo": 0.198381, "log_rr": 0.268988, "p": 0.779896, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.30864, "se": 0.962544, "se_clustered": 0.962544, "se_greenland_robins": 0.630809, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Osteomyelitis": { "all": { "clustered_wider": false, "glp1_affected": 92, "glp1_at_risk": 93765, "hi": 0.957618, "lo": 0.552497, "log_rr": -0.318306, "p": 0.0232918, "placebo_affected": 115, "placebo_at_risk": 67544, "rr": 0.72738, "se": 0.140309, "se_clustered": 0.11997, "se_greenland_robins": 0.140309, "strata_with_events": 27, "trials": 234, "trials_with_events": 27 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 53, "glp1_at_risk": 47388, "hi": 1.11552, "lo": 0.536721, "log_rr": -0.256477, "p": 0.169377, "placebo_affected": 64, "placebo_at_risk": 35018, "rr": 0.773773, "se": 0.186636, "se_clustered": 0.175016, "se_greenland_robins": 0.186636, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 39, "glp1_at_risk": 46377, "hi": 1.01854, "lo": 0.441802, "log_rr": -0.399261, "p": 0.0609664, "placebo_affected": 51, "placebo_at_risk": 32526, "rr": 0.670816, "se": 0.213082, "se_clustered": 0.160788, "se_greenland_robins": 0.213082, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Osteonecrosis": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.77825, "lo": 0.330138, "log_rr": -0.266306, "p": 0.535297, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.766204, "se": 0.429567, "se_clustered": 0.373567, "se_greenland_robins": 0.429567, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 1.72714, "lo": 0.141434, "log_rr": -0.704727, "p": 0.269621, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.494243, "se": 0.638377, "se_clustered": 0.50876, "se_greenland_robins": 0.638377, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.93433, "lo": 0.366791, "log_rr": 0.18339, "p": 0.761907, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.20128, "se": 0.605293, "se_clustered": 0.312913, "se_greenland_robins": 0.605293, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Ovarian cyst": { "all": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 3.42847, "lo": 0.662985, "log_rr": 0.410555, "p": 0.327359, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.50765, "se": 0.41917, "se_clustered": 0.41917, "se_greenland_robins": 0.399938, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 5.58287, "lo": 0.424597, "log_rr": 0.431544, "p": 0.511436, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.53963, "se": 0.657236, "se_clustered": 0.576328, "se_greenland_robins": 0.657236, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.87096, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 4.81313, "lo": 0.460868, "log_rr": 0.398352, "p": 0.505662, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.48937, "se": 0.598478, "se_clustered": 0.598478, "se_greenland_robins": 0.504005, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Overdose": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 5.09207, "lo": 0.744522, "log_rr": 0.666335, "p": 0.174305, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.94709, "se": 0.490493, "se_clustered": 0.490493, "se_greenland_robins": 0.373524, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 12.0209, "lo": 0.881606, "log_rr": 1.18032, "p": 0.0765768, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 3.25541, "se": 0.666506, "se_clustered": 0.344907, "se_greenland_robins": 0.666506, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 4.92915, "lo": 0.433733, "log_rr": 0.37992, "p": 0.540048, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.46217, "se": 0.620035, "se_clustered": 0.620035, "se_greenland_robins": 0.461701, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Pain": { "all": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 93765, "hi": 0.979843, "lo": 0.163708, "log_rr": -0.915016, "p": 0.0450086, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 0.40051, "se": 0.456464, "se_clustered": 0.284825, "se_greenland_robins": 0.456464, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.62347, "lo": 0.174138, "log_rr": -0.63167, "p": 0.267374, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.531703, "se": 0.569519, "se_clustered": 0.305965, "se_greenland_robins": 0.569519, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 1.19155, "lo": 0.0533047, "log_rr": -1.37824, "p": 0.0820606, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.252022, "se": 0.792613, "se_clustered": 0.520992, "se_greenland_robins": 0.792613, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Pain in extremity": { "all": { "clustered_wider": true, "glp1_affected": 27, "glp1_at_risk": 93765, "hi": 1.87287, "lo": 0.576228, "log_rr": 0.0381101, "p": 0.899148, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 1.03885, "se": 0.300701, "se_clustered": 0.300701, "se_greenland_robins": 0.28137, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 47388, "hi": 2.90684, "lo": 0.633422, "log_rr": 0.305225, "p": 0.432313, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 1.35693, "se": 0.388703, "se_clustered": 0.388703, "se_greenland_robins": 0.352111, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.62693, "lo": 0.237065, "log_rr": -0.476363, "p": 0.332312, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.621038, "se": 0.491366, "se_clustered": 0.340942, "se_greenland_robins": 0.491366, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Palpitations": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 1.00202, "lo": 0.252513, "log_rr": -0.687136, "p": 0.0506757, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 0.503014, "se": 0.351617, "se_clustered": 0.330573, "se_greenland_robins": 0.351617, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 0.870709, "lo": 0.168249, "log_rr": -0.960378, "p": 0.0220153, "placebo_affected": 20, "placebo_at_risk": 35018, "rr": 0.382748, "se": 0.41936, "se_clustered": 0.393604, "se_greenland_robins": 0.41936, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.378663, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 4.44311, "lo": 0.275122, "log_rr": 0.100407, "p": 0.887489, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.10562, "se": 0.70968, "se_clustered": 0.50679, "se_greenland_robins": 0.70968, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Pancreatic carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 48, "glp1_at_risk": 93765, "hi": 1.52685, "lo": 0.651608, "log_rr": -0.00255361, "p": 0.990621, "placebo_affected": 43, "placebo_at_risk": 67544, "rr": 0.99745, "se": 0.217227, "se_clustered": 0.151388, "se_greenland_robins": 0.217227, "strata_with_events": 22, "trials": 234, "trials_with_events": 22 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 1.78274, "lo": 0.435589, "log_rr": -0.126452, "p": 0.725028, "placebo_affected": 17, "placebo_at_risk": 35018, "rr": 0.881216, "se": 0.359498, "se_clustered": 0.333086, "se_greenland_robins": 0.359498, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 46377, "hi": 1.83183, "lo": 0.628, "log_rr": 0.0700498, "p": 0.797565, "placebo_affected": 26, "placebo_at_risk": 32526, "rr": 1.07256, "se": 0.273099, "se_clustered": 0.13813, "se_greenland_robins": 0.273099, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Pancreatic carcinoma metastatic": { "all": { "clustered_wider": true, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 1.37116, "lo": 0.449665, "log_rr": -0.241796, "p": 0.395251, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 0.785216, "se": 0.284422, "se_clustered": 0.284422, "se_greenland_robins": 0.272121, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 1.83637, "lo": 0.433197, "log_rr": -0.114386, "p": 0.756227, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.891914, "se": 0.368465, "se_clustered": 0.368465, "se_greenland_robins": 0.351027, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 1.67248, "lo": 0.253009, "log_rr": -0.430011, "p": 0.372124, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 0.650502, "se": 0.481804, "se_clustered": 0.481804, "se_greenland_robins": 0.433894, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Pancreatitis": { "all": 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0.214223, "se_clustered": 0.159735, "se_greenland_robins": 0.214223, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Pancreatitis acute": { "all": { "clustered_wider": false, "glp1_affected": 106, "glp1_at_risk": 93765, "hi": 1.38621, "lo": 0.764451, "log_rr": 0.028989, "p": 0.848582, "placebo_affected": 84, "placebo_at_risk": 67544, "rr": 1.02941, "se": 0.151832, "se_clustered": 0.145937, "se_greenland_robins": 0.151832, "strata_with_events": 38, "trials": 234, "trials_with_events": 37 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 58, "glp1_at_risk": 47388, "hi": 1.32055, "lo": 0.60746, "log_rr": -0.11021, "p": 0.577972, "placebo_affected": 55, "placebo_at_risk": 35018, "rr": 0.895646, "se": 0.198095, "se_clustered": 0.151272, "se_greenland_robins": 0.198095, "strata_with_events": 20, "trials": 117, "trials_with_events": 19 }, "discovery_q": 0.909995, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 48, "glp1_at_risk": 46377, "hi": 2.01784, "lo": 0.792472, "log_rr": 0.234714, "p": 0.32491, "placebo_affected": 29, "placebo_at_risk": 32526, "rr": 1.26455, "se": 0.238429, "se_clustered": 0.220141, "se_greenland_robins": 0.238429, "strata_with_events": 18, "trials": 117, "trials_with_events": 18 } }, "Pancreatitis chronic": { "all": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 2.41632, "lo": 0.440764, "log_rr": 0.0314995, "p": 0.942149, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.032, "se": 0.434061, "se_clustered": 0.276942, "se_greenland_robins": 0.434061, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.41269, "lo": 0.317493, "log_rr": -0.133278, "p": 0.796708, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.875221, "se": 0.517367, "se_clustered": 0.231547, "se_greenland_robins": 0.517367, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 7.85257, "lo": 0.313547, "log_rr": 0.450517, "p": 0.583462, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 1.56912, "se": 0.821609, "se_clustered": 0.816072, "se_greenland_robins": 0.821609, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Pancytopenia": { "all": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 4.41401, "lo": 0.355578, "log_rr": 0.225386, "p": 0.725767, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.25281, "se": 0.642561, "se_clustered": 0.642561, "se_greenland_robins": 0.451939, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 8.81547, "lo": 0.560313, "log_rr": 0.798625, "p": 0.255957, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 2.22248, "se": 0.703015, "se_clustered": 0.327854, "se_greenland_robins": 0.703015, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 7.33403, "lo": 0.0804262, "log_rr": -0.263945, "p": 0.818665, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.768016, "se": 1.15128, "se_clustered": 1.15128, "se_greenland_robins": 0.626193, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Papillary thyroid cancer": { "all": { "clustered_wider": true, "glp1_affected": 36, "glp1_at_risk": 93765, "hi": 2.78329, "lo": 0.787326, "log_rr": 0.392261, "p": 0.223342, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.48032, "se": 0.322135, "se_clustered": 0.322135, "se_greenland_robins": 0.28281, "strata_with_events": 30, "trials": 234, "trials_with_events": 30 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 47388, "hi": 2.48788, "lo": 0.620019, "log_rr": 0.216714, "p": 0.540935, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.24199, "se": 0.354455, "se_clustered": 0.354455, "se_greenland_robins": 0.32984, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 }, "discovery_q": 0.888925, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 10.4808, "lo": 0.483874, "log_rr": 0.811808, "p": 0.300804, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 2.25198, "se": 0.784576, "se_clustered": 0.784576, "se_greenland_robins": 0.561405, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Parathyroid tumour benign": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.79596, "lo": 0.385119, "log_rr": -0.184332, "p": 0.638871, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.83166, "se": 0.392799, "se_clustered": 0.362866, "se_greenland_robins": 0.392799, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 3.65445, "lo": 0.416334, "log_rr": 0.209839, "p": 0.704932, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.23348, "se": 0.554146, "se_clustered": 0.355457, "se_greenland_robins": 0.554146, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 2.08478, "lo": 0.129201, "log_rr": -0.655861, "p": 0.355255, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.518995, "se": 0.709465, "se_clustered": 0.709465, "se_greenland_robins": 0.582944, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Patella fracture": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 2.58403, "lo": 0.644459, "log_rr": 0.255003, "p": 0.471643, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.29047, "se": 0.354266, "se_clustered": 0.250909, "se_greenland_robins": 0.354266, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 3.00325, "lo": 0.408854, "log_rr": 0.102648, "p": 0.840086, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.1081, "se": 0.508706, "se_clustered": 0.265628, "se_greenland_robins": 0.508706, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.956127, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 3.9069, "lo": 0.559692, "log_rr": 0.391188, "p": 0.430017, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.47874, "se": 0.495701, "se_clustered": 0.429085, "se_greenland_robins": 0.495701, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Pelvic fracture": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 3.93535, "lo": 0.975232, "log_rr": 0.672461, "p": 0.0588257, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.95905, "se": 0.355895, "se_clustered": 0.194357, "se_greenland_robins": 0.355895, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 3.59224, "lo": 0.673432, "log_rr": 0.441705, "p": 0.301029, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 1.55536, "se": 0.427086, "se_clustered": 0.139457, "se_greenland_robins": 0.427086, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.82752, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 11.755, "lo": 0.855181, "log_rr": 1.15392, "p": 0.0843533, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 3.17059, "se": 0.668563, "se_clustered": 0.20111, "se_greenland_robins": 0.668563, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Peptic ulcer": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 2.04442, "lo": 0.442205, "log_rr": -0.0504334, "p": 0.897262, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.950817, "se": 0.390593, "se_clustered": 0.325356, "se_greenland_robins": 0.390593, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.9547, "lo": 0.167477, "log_rr": -0.558337, "p": 0.373078, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.57216, "se": 0.626835, "se_clustered": 0.440747, "se_greenland_robins": 0.626835, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 3.78267, "lo": 0.495379, "log_rr": 0.313998, "p": 0.544862, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.36889, "se": 0.518597, "se_clustered": 0.506379, "se_greenland_robins": 0.518597, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Percutaneous coronary intervention": { "all": { "clustered_wider": true, "glp1_affected": 143, "glp1_at_risk": 93765, "hi": 1.05794, "lo": 0.537104, "log_rr": -0.282622, "p": 0.102199, "placebo_affected": 184, "placebo_at_risk": 67544, "rr": 0.753805, "se": 0.172933, "se_clustered": 0.172933, "se_greenland_robins": 0.111828, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 135, "glp1_at_risk": 47388, "hi": 1.12668, "lo": 0.534551, "log_rr": -0.253526, "p": 0.182569, "placebo_affected": 172, "placebo_at_risk": 35018, "rr": 0.776059, "se": 0.190208, "se_clustered": 0.190208, "se_greenland_robins": 0.114864, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.21787, "lo": 0.167549, "log_rr": -0.794688, "p": 0.116309, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.451722, "se": 0.506024, "se_clustered": 0.317976, "se_greenland_robins": 0.506024, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Pericardial effusion": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 1.76223, "lo": 0.469627, "log_rr": -0.0946187, "p": 0.779113, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.90972, "se": 0.337352, "se_clustered": 0.276306, "se_greenland_robins": 0.337352, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.88784, "lo": 0.379088, "log_rr": -0.167277, "p": 0.682953, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.845965, "se": 0.409554, "se_clustered": 0.30074, "se_greenland_robins": 0.409554, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.95392, "lo": 0.287063, "log_rr": 0.0633273, "p": 0.924595, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.06538, "se": 0.669083, "se_clustered": 0.669083, "se_greenland_robins": 0.59753, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Pericarditis": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 0.929761, "lo": 0.263016, "log_rr": -0.704184, "p": 0.0288119, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 0.494512, "se": 0.322126, "se_clustered": 0.243871, "se_greenland_robins": 0.322126, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 1.18117, "lo": 0.21125, "log_rr": -0.694103, "p": 0.113933, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.499522, "se": 0.439095, "se_clustered": 0.38666, "se_greenland_robins": 0.439095, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.23768, "lo": 0.193032, "log_rr": -0.715831, "p": 0.131013, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.488786, "se": 0.474022, "se_clustered": 0.319023, "se_greenland_robins": 0.474022, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Peripheral arterial occlusive disease": { "all": { "clustered_wider": false, "glp1_affected": 225, "glp1_at_risk": 93765, "hi": 0.966887, "lo": 0.674801, "log_rr": -0.213506, "p": 0.0199667, "placebo_affected": 262, "placebo_at_risk": 67544, "rr": 0.807747, "se": 0.0917526, "se_clustered": 0.0584055, "se_greenland_robins": 0.0917526, "strata_with_events": 22, "trials": 234, "trials_with_events": 22 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 136, "glp1_at_risk": 47388, "hi": 1.0176, "lo": 0.646362, "log_rr": -0.209475, "p": 0.0704072, "placebo_affected": 165, "placebo_at_risk": 35018, "rr": 0.81101, "se": 0.115778, "se_clustered": 0.0762363, "se_greenland_robins": 0.115778, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 89, "glp1_at_risk": 46377, "hi": 1.07747, "lo": 0.597451, "log_rr": -0.220232, "p": 0.143207, "placebo_affected": 97, "placebo_at_risk": 32526, "rr": 0.802333, "se": 0.150437, "se_clustered": 0.0927923, "se_greenland_robins": 0.150437, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Peripheral artery aneurysm": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 4.42139, "lo": 0.795128, "log_rr": 0.628601, "p": 0.15095, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.87499, "se": 0.437688, "se_clustered": 0.312762, "se_greenland_robins": 0.437688, "strata_with_events": 6, "trials": 234, "trials_with_events": 6 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 4.95413, "lo": 0.80742, "log_rr": 0.693155, "p": 0.134198, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 2.00002, "se": 0.462798, "se_clustered": 0.308576, "se_greenland_robins": 0.462798, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.692463, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 50.3978, "lo": 0.0198429, "log_rr": 2.02545e-05, "p": 0.999992, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 1.00002, "se": 2.0, "se_clustered": 2.0, "se_greenland_robins": 1.4138, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Peripheral artery angioplasty": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 1.40582, "lo": 0.474729, "log_rr": -0.202195, "p": 0.465346, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 0.816936, "se": 0.276952, "se_clustered": 0.131652, "se_greenland_robins": 0.276952, "strata_with_events": 3, "trials": 234, "trials_with_events": 3 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 47388, "hi": 1.3199, "lo": 0.416423, "log_rr": -0.299248, "p": 0.309232, "placebo_affected": 27, "placebo_at_risk": 35018, "rr": 0.741375, "se": 0.294294, "se_clustered": null, "se_greenland_robins": 0.294294, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 }, "discovery_q": 0.827638, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 10.6194, "lo": 0.31773, "log_rr": 0.608063, "p": 0.496994, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 1.83687, "se": 0.895228, "se_clustered": 0.365797, "se_greenland_robins": 0.895228, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Peripheral artery bypass": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 1.68902, "lo": 0.391488, "log_rr": -0.206826, "p": 0.579192, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.813161, "se": 0.372953, "se_clustered": 0.140061, "se_greenland_robins": 0.372953, "strata_with_events": 3, "trials": 234, "trials_with_events": 3 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.59634, "lo": 0.337447, "log_rr": -0.309316, "p": 0.435266, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.733949, "se": 0.396451, "se_clustered": 0.133366, "se_greenland_robins": 0.396451, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 }, "discovery_q": 0.848267, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 22.0484, "lo": 0.18164, "log_rr": 0.693754, "p": 0.570934, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 2.00121, "se": 1.22425, "se_clustered": null, "se_greenland_robins": 1.22425, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 } }, "Peripheral artery occlusion": { "all": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 93765, "hi": 1.653, "lo": 0.651858, "log_rr": 0.0373305, "p": 0.875041, "placebo_affected": 35, "placebo_at_risk": 67544, "rr": 1.03804, "se": 0.237382, "se_clustered": 0.231582, "se_greenland_robins": 0.237382, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 47388, "hi": 1.90359, "lo": 0.576384, "log_rr": 0.0463801, "p": 0.879049, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.04747, "se": 0.304781, "se_clustered": 0.267396, "se_greenland_robins": 0.304781, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.969208, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 2.62154, "lo": 0.399891, "log_rr": 0.023599, "p": 0.960762, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 1.02388, "se": 0.479684, "se_clustered": 0.479684, "se_greenland_robins": 0.378464, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Peripheral artery stenosis": { "all": { "clustered_wider": false, "glp1_affected": 44, "glp1_at_risk": 93765, "hi": 1.29014, "lo": 0.572699, "log_rr": -0.151323, "p": 0.465156, "placebo_affected": 50, "placebo_at_risk": 67544, "rr": 0.85957, "se": 0.207184, "se_clustered": 0.129203, "se_greenland_robins": 0.207184, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 47388, "hi": 1.51699, "lo": 0.611512, "log_rr": -0.0375469, "p": 0.871309, "placebo_affected": 38, "placebo_at_risk": 35018, "rr": 0.963149, "se": 0.231777, "se_clustered": 0.162334, "se_greenland_robins": 0.231777, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.962731, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.37853, "lo": 0.211885, "log_rr": -0.615346, "p": 0.197739, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.540454, "se": 0.477745, "se_clustered": 0.304163, "se_greenland_robins": 0.477745, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Peripheral artery stent insertion": { "all": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 4.63215, "lo": 0.363653, "log_rr": 0.260733, "p": 0.687934, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.29788, "se": 0.649139, "se_clustered": 0.649139, "se_greenland_robins": 0.445695, "strata_with_events": 3, "trials": 234, "trials_with_events": 3 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.08848, "lo": 0.290151, "log_rr": -0.250458, "p": 0.618902, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.778444, "se": 0.503528, "se_clustered": null, "se_greenland_robins": 0.503528, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 }, "discovery_q": 0.912598, "replicated": false, "replication": { "glp1_affected": 5, "glp1_at_risk": 46377, "hi": null, "lo": null, "p": null, "placebo_affected": 0, "placebo_at_risk": 32526, "rr": null, "se": null, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 } }, "Peripheral artery thrombosis": { "all": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 2.24413, "lo": 0.60698, "log_rr": 0.154529, "p": 0.643181, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.16711, "se": 0.333572, "se_clustered": 0.210272, "se_greenland_robins": 0.333572, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 2.30663, "lo": 0.433766, "log_rr": 0.000269162, "p": 0.999496, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.00027, "se": 0.426293, "se_clustered": 0.257027, "se_greenland_robins": 0.426293, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 4.25564, "lo": 0.509894, "log_rr": 0.387346, "p": 0.474236, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.47307, "se": 0.541285, "se_clustered": 0.401737, "se_greenland_robins": 0.541285, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Peripheral ischaemia": { "all": { "clustered_wider": true, "glp1_affected": 65, "glp1_at_risk": 93765, "hi": 1.125, "lo": 0.575299, "log_rr": -0.217541, "p": 0.203543, "placebo_affected": 78, "placebo_at_risk": 67544, "rr": 0.804495, "se": 0.171087, "se_clustered": 0.171087, "se_greenland_robins": 0.166875, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 42, "glp1_at_risk": 47388, "hi": 1.43365, "lo": 0.619982, "log_rr": -0.0589217, "p": 0.782913, "placebo_affected": 44, "placebo_at_risk": 35018, "rr": 0.942781, "se": 0.213852, "se_clustered": 0.171569, "se_greenland_robins": 0.213852, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 23, "glp1_at_risk": 46377, "hi": 1.06723, "lo": 0.370089, "log_rr": -0.464471, "p": 0.0855904, "placebo_affected": 34, "placebo_at_risk": 32526, "rr": 0.628467, "se": 0.270178, "se_clustered": 0.230895, "se_greenland_robins": 0.270178, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Peripheral revascularisation": { "all": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 93765, "hi": 1.07754, "lo": 0.455468, "log_rr": -0.355875, "p": 0.105231, "placebo_affected": 50, "placebo_at_risk": 67544, "rr": 0.70056, "se": 0.219675, "se_clustered": 0.217229, "se_greenland_robins": 0.219675, "strata_with_events": 2, "trials": 234, "trials_with_events": 2 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 47388, "hi": 1.31259, "lo": 0.49523, "log_rr": -0.215367, "p": 0.386432, "placebo_affected": 36, "placebo_at_risk": 35018, "rr": 0.806246, "se": 0.248661, "se_clustered": null, "se_greenland_robins": 0.248661, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 1.11319, "lo": 0.165197, "log_rr": -0.846691, "p": 0.0819225, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.428831, "se": 0.486705, "se_clustered": null, "se_greenland_robins": 0.486705, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 } }, "Peripheral vascular disorder": { "all": { "clustered_wider": true, "glp1_affected": 41, "glp1_at_risk": 93765, "hi": 0.974389, "lo": 0.360458, "log_rr": -0.523162, "p": 0.0391855, "placebo_affected": 64, "placebo_at_risk": 67544, "rr": 0.592644, "se": 0.253687, "se_clustered": 0.253687, "se_greenland_robins": 0.197967, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 47388, "hi": 1.49193, "lo": 0.532192, "log_rr": -0.115341, "p": 0.660943, "placebo_affected": 30, "placebo_at_risk": 35018, "rr": 0.891062, "se": 0.262969, "se_clustered": 0.198199, "se_greenland_robins": 0.262969, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.919264, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 1.00763, "lo": 0.115419, "log_rr": -1.07579, "p": 0.0516296, "placebo_affected": 34, "placebo_at_risk": 32526, "rr": 0.341028, "se": 0.552762, "se_clustered": 0.552762, "se_greenland_robins": 0.320813, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Peritonitis": { "all": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 1.10031, "lo": 0.362001, "log_rr": -0.460257, "p": 0.104612, "placebo_affected": 32, "placebo_at_risk": 67544, "rr": 0.631122, "se": 0.283603, "se_clustered": 0.268658, "se_greenland_robins": 0.283603, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.03468, "lo": 0.258285, "log_rr": -0.659801, "p": 0.0623673, "placebo_affected": 23, "placebo_at_risk": 35018, "rr": 0.516954, "se": 0.354032, "se_clustered": 0.197353, "se_greenland_robins": 0.354032, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 4.71165, "lo": 0.181832, "log_rr": -0.0773171, "p": 0.925809, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.925596, "se": 0.830299, "se_clustered": 0.830299, "se_greenland_robins": 0.486711, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Plasma cell myeloma": { "all": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 93765, "hi": 1.84653, "lo": 0.648922, "log_rr": 0.0904333, "p": 0.734623, "placebo_affected": 26, "placebo_at_risk": 67544, "rr": 1.09465, "se": 0.266779, "se_clustered": 0.188437, "se_greenland_robins": 0.266779, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 2.22753, "lo": 0.547197, "log_rr": 0.098973, "p": 0.78227, "placebo_affected": 14, "placebo_at_risk": 35018, "rr": 1.10404, "se": 0.358129, "se_clustered": 0.262943, "se_greenland_robins": 0.358129, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 2.37188, "lo": 0.494791, "log_rr": 0.0800317, "p": 0.841352, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.08332, "se": 0.399829, "se_clustered": 0.297091, "se_greenland_robins": 0.399829, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Pleural effusion": { "all": { "clustered_wider": true, "glp1_affected": 78, "glp1_at_risk": 93765, "hi": 1.24282, "lo": 0.611209, "log_rr": -0.137467, "p": 0.447681, "placebo_affected": 87, "placebo_at_risk": 67544, "rr": 0.871563, "se": 0.181048, "se_clustered": 0.181048, "se_greenland_robins": 0.156922, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 39, "glp1_at_risk": 47388, "hi": 1.20374, "lo": 0.459022, "log_rr": -0.296614, "p": 0.227811, "placebo_affected": 51, "placebo_at_risk": 35018, "rr": 0.743331, "se": 0.245945, "se_clustered": 0.245945, "se_greenland_robins": 0.21483, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 39, "glp1_at_risk": 46377, "hi": 1.72999, "lo": 0.639275, "log_rr": 0.0503479, "p": 0.842854, "placebo_affected": 36, "placebo_at_risk": 32526, "rr": 1.05164, "se": 0.253969, "se_clustered": 0.253969, "se_greenland_robins": 0.231603, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Pneumonia": { "all": { "clustered_wider": false, "glp1_affected": 807, "glp1_at_risk": 93765, "hi": 0.95087, "lo": 0.786347, "log_rr": -0.145367, "p": 0.00270483, "placebo_affected": 880, "placebo_at_risk": 67544, "rr": 0.864705, "se": 0.048465, "se_clustered": 0.0476123, "se_greenland_robins": 0.048465, "strata_with_events": 80, "trials": 234, "trials_with_events": 78 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 440, "glp1_at_risk": 47388, "hi": 0.996013, "lo": 0.718411, "log_rr": -0.167354, "p": 0.0446541, "placebo_affected": 501, "placebo_at_risk": 35018, "rr": 0.8459, "se": 0.083348, "se_clustered": 0.083348, "se_greenland_robins": 0.0649554, "strata_with_events": 40, "trials": 117, "trials_with_events": 38 }, "discovery_q": 0.512034, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 367, "glp1_at_risk": 46377, "hi": 1.02549, "lo": 0.770891, "log_rr": -0.117517, "p": 0.106488, "placebo_affected": 379, "placebo_at_risk": 32526, "rr": 0.889125, "se": 0.0728029, "se_clustered": 0.0254934, "se_greenland_robins": 0.0728029, "strata_with_events": 40, "trials": 117, "trials_with_events": 40 } }, "Pneumonia aspiration": { "all": { "clustered_wider": false, "glp1_affected": 42, "glp1_at_risk": 93765, "hi": 1.46494, "lo": 0.626359, "log_rr": -0.0430082, "p": 0.842714, "placebo_affected": 43, "placebo_at_risk": 67544, "rr": 0.957904, "se": 0.21675, "se_clustered": 0.127022, "se_greenland_robins": 0.21675, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 47388, "hi": 1.48377, "lo": 0.530765, "log_rr": -0.119424, "p": 0.648842, "placebo_affected": 31, "placebo_at_risk": 35018, "rr": 0.887432, "se": 0.262256, "se_clustered": 0.0978069, "se_greenland_robins": 0.262256, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 2.42308, "lo": 0.531662, "log_rr": 0.126647, "p": 0.74344, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 1.13502, "se": 0.386943, "se_clustered": 0.311405, "se_greenland_robins": 0.386943, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Pneumonia bacterial": { "all": { "clustered_wider": true, "glp1_affected": 35, "glp1_at_risk": 93765, "hi": 1.82016, "lo": 0.474179, "log_rr": -0.0736235, "p": 0.830113, "placebo_affected": 36, "placebo_at_risk": 67544, "rr": 0.929021, "se": 0.343143, "se_clustered": 0.343143, "se_greenland_robins": 0.241519, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 47388, "hi": 2.12235, "lo": 0.684028, "log_rr": 0.186383, "p": 0.518762, "placebo_affected": 22, "placebo_at_risk": 35018, "rr": 1.20488, "se": 0.288852, "se_clustered": 0.24129, "se_greenland_robins": 0.288852, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.872335, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.24827, "lo": 0.196771, "log_rr": -0.701979, "p": 0.136371, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.495604, "se": 0.471304, "se_clustered": 0.461445, "se_greenland_robins": 0.471304, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Pneumonia viral": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 2.46589, "lo": 0.625267, "log_rr": 0.216489, "p": 0.536267, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.24171, "se": 0.35004, "se_clustered": 0.282441, "se_greenland_robins": 0.35004, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.69301, "lo": 0.54178, "log_rr": 0.188882, "p": 0.644277, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 1.2079, "se": 0.409077, "se_clustered": 0.320788, "se_greenland_robins": 0.409077, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 5.10981, "lo": 0.348627, "log_rr": 0.288705, "p": 0.673387, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.3347, "se": 0.68494, "se_clustered": 0.68494, "se_greenland_robins": 0.676535, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Pneumothorax": { "all": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 1.34657, "lo": 0.438764, "log_rr": -0.263117, "p": 0.357688, "placebo_affected": 27, "placebo_at_risk": 67544, "rr": 0.768652, "se": 0.286065, "se_clustered": 0.161906, "se_greenland_robins": 0.286065, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.97676, "lo": 0.397823, "log_rr": -0.120144, "p": 0.768942, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.886792, "se": 0.408989, "se_clustered": 0.22023, "se_greenland_robins": 0.408989, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 1.48016, "lo": 0.306199, "log_rr": -0.395685, "p": 0.324928, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 0.673219, "se": 0.401963, "se_clustered": 0.210234, "se_greenland_robins": 0.401963, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Post procedural haematoma": { "all": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 2.83898, "lo": 0.431036, "log_rr": 0.10094, "p": 0.83374, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.10621, "se": 0.480879, "se_clustered": 0.480879, "se_greenland_robins": 0.442026, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 10.6348, "lo": 0.693934, "log_rr": 0.999376, "p": 0.151221, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 2.71659, "se": 0.696316, "se_clustered": 0.696316, "se_greenland_robins": 0.61286, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.709363, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 1.38563, "lo": 0.0200586, "log_rr": -1.79147, "p": 0.0972989, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.166715, "se": 1.08044, "se_clustered": 0.90237, "se_greenland_robins": 1.08044, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Post procedural haemorrhage": { "all": { "clustered_wider": false, "glp1_affected": 39, "glp1_at_risk": 93765, "hi": 2.97411, "lo": 1.00875, "log_rr": 0.549326, "p": 0.0464222, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.73209, "se": 0.275831, "se_clustered": 0.275552, "se_greenland_robins": 0.275831, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 47388, "hi": 3.25719, "lo": 0.797046, "log_rr": 0.477011, "p": 0.184081, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 1.61125, "se": 0.359116, "se_clustered": 0.319046, "se_greenland_robins": 0.359116, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 5.14556, "lo": 0.710554, "log_rr": 0.648212, "p": 0.19935, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.91212, "se": 0.505071, "se_clustered": 0.505071, "se_greenland_robins": 0.431325, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Post procedural infection": { "all": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 2.07317, "lo": 0.492269, "log_rr": 0.0101745, "p": 0.97787, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.01023, "se": 0.366795, "se_clustered": 0.366795, "se_greenland_robins": 0.344417, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 2.72003, "lo": 0.378158, "log_rr": 0.0140992, "p": 0.977653, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 1.0142, "se": 0.503347, "se_clustered": 0.503347, "se_greenland_robins": 0.410675, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 3.45544, "lo": 0.289798, "log_rr": 0.0006895, "p": 0.99913, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.00069, "se": 0.632287, "se_clustered": 0.462027, "se_greenland_robins": 0.632287, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Postoperative wound infection": { "all": { "clustered_wider": false, "glp1_affected": 60, "glp1_at_risk": 93765, "hi": 1.90411, "lo": 0.852706, "log_rr": 0.242336, "p": 0.237019, "placebo_affected": 43, "placebo_at_risk": 67544, "rr": 1.27422, "se": 0.204941, "se_clustered": 0.143858, "se_greenland_robins": 0.204941, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 47388, "hi": 1.66971, "lo": 0.60185, "log_rr": 0.00245271, "p": 0.992482, "placebo_affected": 29, "placebo_at_risk": 35018, "rr": 1.00246, "se": 0.260311, "se_clustered": 0.166376, "se_greenland_robins": 0.260311, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 46377, "hi": 3.59738, "lo": 0.944674, "log_rr": 0.611645, "p": 0.0729553, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 1.84346, "se": 0.341109, "se_clustered": 0.234995, "se_greenland_robins": 0.341109, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Presyncope": { "all": { "clustered_wider": false, "glp1_affected": 49, "glp1_at_risk": 93765, "hi": 1.90055, "lo": 0.797071, "log_rr": 0.207665, "p": 0.348864, "placebo_affected": 37, "placebo_at_risk": 67544, "rr": 1.2308, "se": 0.221676, "se_clustered": 0.172443, "se_greenland_robins": 0.221676, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 47388, "hi": 1.8705, "lo": 0.658797, "log_rr": 0.104432, "p": 0.694847, "placebo_affected": 27, "placebo_at_risk": 35018, "rr": 1.11008, "se": 0.266215, "se_clustered": 0.184627, "se_greenland_robins": 0.266215, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 46377, "hi": 3.41129, "lo": 0.700192, "log_rr": 0.435345, "p": 0.28117, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.5455, "se": 0.40396, "se_clustered": 0.304489, "se_greenland_robins": 0.40396, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Procedural pain": { "all": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 2.23805, "lo": 0.347123, "log_rr": -0.126234, "p": 0.790616, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.881409, "se": 0.475438, "se_clustered": 0.450606, "se_greenland_robins": 0.475438, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.2443, "lo": 0.265785, "log_rr": -0.258338, "p": 0.63503, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.772334, "se": 0.54426, "se_clustered": 0.483207, "se_greenland_robins": 0.54426, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.917467, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 15.8327, "lo": 0.109708, "log_rr": 0.276071, "p": 0.827699, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 1.31794, "se": 1.2684, "se_clustered": 1.2684, "se_greenland_robins": 1.00106, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Prostate cancer": { "all": { "clustered_wider": true, "glp1_affected": 235, "glp1_at_risk": 93765, "hi": 1.24733, "lo": 0.780932, "log_rr": -0.0131307, "p": 0.912475, "placebo_affected": 223, "placebo_at_risk": 67544, "rr": 0.986955, "se": 0.11946, "se_clustered": 0.11946, "se_greenland_robins": 0.0939989, "strata_with_events": 41, "trials": 234, "trials_with_events": 41 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 146, "glp1_at_risk": 47388, "hi": 1.46287, "lo": 0.73544, "log_rr": 0.0365558, "p": 0.834936, "placebo_affected": 134, "placebo_at_risk": 35018, "rr": 1.03723, "se": 0.175433, "se_clustered": 0.175433, "se_greenland_robins": 0.119535, "strata_with_events": 19, "trials": 117, "trials_with_events": 19 }, "discovery_q": 0.955271, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 89, "glp1_at_risk": 46377, "hi": 1.22849, "lo": 0.676098, "log_rr": -0.0928144, "p": 0.542383, "placebo_affected": 89, "placebo_at_risk": 32526, "rr": 0.911363, "se": 0.152351, "se_clustered": 0.117922, "se_greenland_robins": 0.152351, "strata_with_events": 22, "trials": 117, "trials_with_events": 22 } }, "Prostate cancer metastatic": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 1.22115, "lo": 0.437382, "log_rr": -0.313577, "p": 0.231236, "placebo_affected": 31, "placebo_at_risk": 67544, "rr": 0.730828, "se": 0.261929, "se_clustered": 0.17445, "se_greenland_robins": 0.261929, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 1.48502, "lo": 0.421485, "log_rr": -0.23427, "p": 0.465896, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.791148, "se": 0.321282, "se_clustered": 0.18742, "se_greenland_robins": 0.321282, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.5009, "lo": 0.253363, "log_rr": -0.483433, "p": 0.286776, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.616663, "se": 0.453834, "se_clustered": 0.388906, "se_greenland_robins": 0.453834, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Prostatic adenoma": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 3.29054, "lo": 0.654579, "log_rr": 0.383643, "p": 0.351705, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.46762, "se": 0.41195, "se_clustered": 0.320461, "se_greenland_robins": 0.41195, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 3.22643, "lo": 0.215502, "log_rr": -0.181706, "p": 0.792393, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.833847, "se": 0.69036, "se_clustered": 0.69036, "se_greenland_robins": 0.605683, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 7.82555, "lo": 0.747149, "log_rr": 0.882952, "p": 0.140613, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 2.41803, "se": 0.599216, "se_clustered": 0.337931, "se_greenland_robins": 0.599216, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Prostatitis": { "all": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 93765, "hi": 2.57843, "lo": 0.813758, "log_rr": 0.370544, "p": 0.207862, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 1.44852, "se": 0.294207, "se_clustered": 0.255955, "se_greenland_robins": 0.294207, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 47388, "hi": 4.66583, "lo": 0.955632, "log_rr": 0.747441, "p": 0.0646354, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 2.11159, "se": 0.40451, "se_clustered": 0.221757, "se_greenland_robins": 0.40451, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 2.32138, "lo": 0.326857, "log_rr": -0.138036, "p": 0.782539, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.871067, "se": 0.50011, "se_clustered": 0.50011, "se_greenland_robins": 0.450531, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Prostatomegaly": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.81847, "lo": 0.64041, "log_rr": 0.447102, "p": 0.326307, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.56377, "se": 0.455492, "se_clustered": 0.448821, "se_greenland_robins": 0.455492, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 6.87212, "lo": 0.704497, "log_rr": 0.7886, "p": 0.174731, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 2.20031, "se": 0.581068, "se_clustered": 0.581068, "se_greenland_robins": 0.539273, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 3.75466, "lo": 0.0671021, "log_rr": -0.689272, "p": 0.501994, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 0.501942, "se": 1.02669, "se_clustered": 0.769562, "se_greenland_robins": 1.02669, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Pulmonary embolism": { "all": { "clustered_wider": false, "glp1_affected": 144, "glp1_at_risk": 93765, "hi": 1.00738, "lo": 0.643412, "log_rr": -0.216809, "p": 0.0580037, "placebo_affected": 160, "placebo_at_risk": 67544, "rr": 0.805084, "se": 0.11437, "se_clustered": 0.0761273, "se_greenland_robins": 0.11437, "strata_with_events": 37, "trials": 234, "trials_with_events": 36 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 91, "glp1_at_risk": 47388, "hi": 1.05065, "lo": 0.603024, "log_rr": -0.228197, "p": 0.107147, "placebo_affected": 106, "placebo_at_risk": 35018, "rr": 0.795967, "se": 0.141636, "se_clustered": 0.0850551, "se_greenland_robins": 0.141636, "strata_with_events": 18, "trials": 117, "trials_with_events": 17 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 53, "glp1_at_risk": 46377, "hi": 1.20277, "lo": 0.562439, "log_rr": -0.195424, "p": 0.313537, "placebo_affected": 54, "placebo_at_risk": 32526, "rr": 0.822486, "se": 0.193906, "se_clustered": 0.155323, "se_greenland_robins": 0.193906, "strata_with_events": 19, "trials": 117, "trials_with_events": 19 } }, "Pulmonary fibrosis": { "all": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 93765, "hi": 1.23918, "lo": 0.208911, "log_rr": -0.675699, "p": 0.136809, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 0.508801, "se": 0.454166, "se_clustered": 0.34534, "se_greenland_robins": 0.454166, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.98194, "lo": 0.145721, "log_rr": -0.620993, "p": 0.35102, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.53741, "se": 0.665864, "se_clustered": 0.398489, "se_greenland_robins": 0.665864, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.64242, "lo": 0.143909, "log_rr": -0.721202, "p": 0.245588, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.486168, "se": 0.62112, "se_clustered": 0.571694, "se_greenland_robins": 0.62112, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Pulmonary hypertension": { "all": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 2.61853, "lo": 0.722549, "log_rr": 0.318821, "p": 0.331737, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 1.37551, "se": 0.328471, "se_clustered": 0.261226, "se_greenland_robins": 0.328471, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 2.58989, "lo": 0.467465, "log_rr": 0.0955916, "p": 0.826753, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 1.10031, "se": 0.436755, "se_clustered": 0.188154, "se_greenland_robins": 0.436755, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.94801, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 5.63846, "lo": 0.596723, "log_rr": 0.606654, "p": 0.289677, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.83428, "se": 0.572947, "se_clustered": 0.572947, "se_greenland_robins": 0.50746, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Pulmonary mass": { "all": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 2.88184, "lo": 0.591889, "log_rr": 0.266996, "p": 0.508478, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 1.30604, "se": 0.4038, "se_clustered": 0.4038, "se_greenland_robins": 0.358679, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 3.78569, "lo": 0.395628, "log_rr": 0.201974, "p": 0.725925, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 1.22382, "se": 0.576161, "se_clustered": 0.576161, "se_greenland_robins": 0.449193, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 4.74071, "lo": 0.456208, "log_rr": 0.38569, "p": 0.518391, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.47063, "se": 0.597203, "se_clustered": 0.537129, "se_greenland_robins": 0.597203, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Pulmonary oedema": { "all": { "clustered_wider": false, "glp1_affected": 74, "glp1_at_risk": 93765, "hi": 0.90413, "lo": 0.489771, "log_rr": -0.407299, "p": 0.00920356, "placebo_affected": 103, "placebo_at_risk": 67544, "rr": 0.665445, "se": 0.156389, "se_clustered": 0.138452, "se_greenland_robins": 0.156389, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 47388, "hi": 1.09513, "lo": 0.472595, "log_rr": -0.329322, "p": 0.124515, "placebo_affected": 52, "placebo_at_risk": 35018, "rr": 0.719411, "se": 0.214389, "se_clustered": 0.122208, "se_greenland_robins": 0.214389, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.669269, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 36, "glp1_at_risk": 46377, "hi": 0.978912, "lo": 0.381083, "log_rr": -0.493025, "p": 0.0405088, "placebo_affected": 51, "placebo_at_risk": 32526, "rr": 0.610776, "se": 0.240674, "se_clustered": 0.240674, "se_greenland_robins": 0.228959, "strata_with_events": 15, "trials": 117, "trials_with_events": 15 } }, "Pulmonary sepsis": { "all": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 2.591, "lo": 0.467478, "log_rr": 0.0958205, "p": 0.826384, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.10056, "se": 0.436857, "se_clustered": 0.393076, "se_greenland_robins": 0.436857, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 1.66066, "lo": 0.150636, "log_rr": -0.692837, "p": 0.257817, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.500155, "se": 0.612282, "se_clustered": 0.456403, "se_greenland_robins": 0.612282, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 16.8627, "lo": 0.727819, "log_rr": 1.2537, "p": 0.117888, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 3.50328, "se": 0.801751, "se_clustered": 0.654396, "se_greenland_robins": 0.801751, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Pyelonephritis": { "all": { "clustered_wider": false, "glp1_affected": 66, "glp1_at_risk": 93765, "hi": 1.33593, "lo": 0.652983, "log_rr": -0.0682892, "p": 0.708437, "placebo_affected": 61, "placebo_at_risk": 67544, "rr": 0.93399, "se": 0.182613, "se_clustered": 0.163341, "se_greenland_robins": 0.182613, "strata_with_events": 27, "trials": 234, "trials_with_events": 27 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 47388, "hi": 1.75504, "lo": 0.6772, "log_rr": 0.0863505, "p": 0.722252, "placebo_affected": 33, "placebo_at_risk": 35018, "rr": 1.09019, "se": 0.242932, "se_clustered": 0.182305, "se_greenland_robins": 0.242932, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 46377, "hi": 1.31474, "lo": 0.439654, "log_rr": -0.274062, "p": 0.326725, "placebo_affected": 28, "placebo_at_risk": 32526, "rr": 0.760285, "se": 0.279446, "se_clustered": 0.243435, "se_greenland_robins": 0.279446, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Pyelonephritis acute": { "all": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 93765, "hi": 1.33595, "lo": 0.530407, "log_rr": -0.172234, "p": 0.464859, "placebo_affected": 38, "placebo_at_risk": 67544, "rr": 0.841782, "se": 0.235656, "se_clustered": 0.15845, "se_greenland_robins": 0.235656, "strata_with_events": 23, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 1.43025, "lo": 0.403438, "log_rr": -0.274942, "p": 0.394444, "placebo_affected": 22, "placebo_at_risk": 35018, "rr": 0.759616, "se": 0.322859, "se_clustered": 0.263722, "se_greenland_robins": 0.322859, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 1.86872, "lo": 0.481654, "log_rr": -0.0526384, "p": 0.879036, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 0.948723, "se": 0.345869, "se_clustered": 0.185233, "se_greenland_robins": 0.345869, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Pyrexia": { "all": { "clustered_wider": true, "glp1_affected": 46, "glp1_at_risk": 93765, "hi": 1.62661, "lo": 0.549815, "log_rr": -0.0558358, "p": 0.840084, "placebo_affected": 45, "placebo_at_risk": 67544, "rr": 0.945694, "se": 0.276708, "se_clustered": 0.276708, "se_greenland_robins": 0.20995, "strata_with_events": 22, "trials": 234, "trials_with_events": 22 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 27, "glp1_at_risk": 47388, "hi": 2.40573, "lo": 0.650795, "log_rr": 0.224146, "p": 0.501556, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.25125, "se": 0.33353, "se_clustered": 0.33353, "se_greenland_robins": 0.289769, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.865562, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 1.30038, "lo": 0.360897, "log_rr": -0.378255, "p": 0.247377, "placebo_affected": 24, "placebo_at_risk": 32526, "rr": 0.685056, "se": 0.327, "se_clustered": 0.327, "se_greenland_robins": 0.312003, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Radius fracture": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 1.15133, "lo": 0.410882, "log_rr": -0.374263, "p": 0.154492, "placebo_affected": 32, "placebo_at_risk": 67544, "rr": 0.687796, "se": 0.262854, "se_clustered": 0.231861, "se_greenland_robins": 0.262854, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 1.04612, "lo": 0.221105, "log_rr": -0.732015, "p": 0.0648567, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.480939, "se": 0.396489, "se_clustered": 0.235555, "se_greenland_robins": 0.396489, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.577559, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 1.90688, "lo": 0.46548, "log_rr": -0.0596073, "p": 0.868397, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.942134, "se": 0.35974, "se_clustered": 0.317382, "se_greenland_robins": 0.35974, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Rectal adenocarcinoma": { "all": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 2.22658, "lo": 0.672836, "log_rr": 0.202106, "p": 0.507964, "placebo_affected": 19, "placebo_at_risk": 67544, "rr": 1.22398, "se": 0.305291, "se_clustered": 0.278364, "se_greenland_robins": 0.305291, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.45491, "lo": 0.512457, "log_rr": 0.114776, "p": 0.773971, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 1.12162, "se": 0.399658, "se_clustered": 0.399658, "se_greenland_robins": 0.3838, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 3.78333, "lo": 0.523067, "log_rr": 0.341279, "p": 0.49897, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.40675, "se": 0.504767, "se_clustered": 0.449675, "se_greenland_robins": 0.504767, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Rectal cancer": { "all": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 2.84514, "lo": 0.695976, "log_rr": 0.341586, "p": 0.341628, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.40718, "se": 0.359203, "se_clustered": 0.359203, "se_greenland_robins": 0.346633, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 3.75685, "lo": 0.517738, "log_rr": 0.332648, "p": 0.510574, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.39466, "se": 0.505587, "se_clustered": 0.35293, "se_greenland_robins": 0.505587, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.87096, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 4.88865, "lo": 0.411818, "log_rr": 0.349871, "p": 0.579351, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.41888, "se": 0.631157, "se_clustered": 0.631157, "se_greenland_robins": 0.475941, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Rectal haemorrhage": { "all": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 93765, "hi": 1.68346, "lo": 0.621962, "log_rr": 0.022988, "p": 0.927892, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 1.02325, "se": 0.254017, "se_clustered": 0.172441, "se_greenland_robins": 0.254017, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 47388, "hi": 2.03889, "lo": 0.558634, "log_rr": 0.0650727, "p": 0.843809, "placebo_affected": 17, "placebo_at_risk": 35018, "rr": 1.06724, "se": 0.330278, "se_clustered": 0.246328, "se_greenland_robins": 0.330278, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.956127, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.09688, "lo": 0.441043, "log_rr": -0.0390817, "p": 0.921724, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.961672, "se": 0.397727, "se_clustered": 0.255049, "se_greenland_robins": 0.397727, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Renal artery stenosis": { "all": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 2.2686, "lo": 0.2951, "log_rr": -0.200638, "p": 0.699787, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.818208, "se": 0.520317, "se_clustered": 0.520317, "se_greenland_robins": 0.449354, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 3.86915, "lo": 0.179612, "log_rr": -0.18196, "p": 0.816277, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.833635, "se": 0.783175, "se_clustered": 0.783175, "se_greenland_robins": 0.605445, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.942279, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 4.03835, "lo": 0.158363, "log_rr": -0.223513, "p": 0.786755, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.799704, "se": 0.826214, "se_clustered": 0.826214, "se_greenland_robins": 0.670564, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Renal cancer": { "all": { "clustered_wider": true, "glp1_affected": 25, "glp1_at_risk": 93765, "hi": 2.41742, "lo": 0.578796, "log_rr": 0.167947, "p": 0.645131, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.18287, "se": 0.364676, "se_clustered": 0.364676, "se_greenland_robins": 0.293787, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 7.12699, "lo": 0.422963, "log_rr": 0.551709, "p": 0.443845, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.73622, "se": 0.720513, "se_clustered": 0.720513, "se_greenland_robins": 0.450161, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 1.90354, "lo": 0.400318, "log_rr": -0.135889, "p": 0.732628, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 0.872939, "se": 0.397765, "se_clustered": 0.251014, "se_greenland_robins": 0.397765, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Renal cell carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 1.61221, "lo": 0.562667, "log_rr": -0.0487295, "p": 0.856008, "placebo_affected": 28, "placebo_at_risk": 67544, "rr": 0.952439, "se": 0.268545, "se_clustered": 0.219087, "se_greenland_robins": 0.268545, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.19426, "lo": 0.467564, "log_rr": 0.0128131, "p": 0.974084, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.0129, "se": 0.394412, "se_clustered": 0.385461, "se_greenland_robins": 0.394412, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 1.85206, "lo": 0.439538, "log_rr": -0.102867, "p": 0.779211, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 0.902247, "se": 0.366927, "se_clustered": 0.255009, "se_greenland_robins": 0.366927, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Renal colic": { "all": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 93765, "hi": 2.66679, "lo": 0.883282, "log_rr": 0.428383, "p": 0.128591, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 1.53477, "se": 0.28189, "se_clustered": 0.231587, "se_greenland_robins": 0.28189, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 3.96675, "lo": 0.689228, "log_rr": 0.502882, "p": 0.260017, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.65348, "se": 0.44647, "se_clustered": 0.431079, "se_greenland_robins": 0.44647, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 46377, "hi": 2.97795, "lo": 0.71553, "log_rr": 0.378252, "p": 0.298433, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 1.45973, "se": 0.363774, "se_clustered": 0.274048, "se_greenland_robins": 0.363774, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Renal cyst": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 1.45039, "lo": 0.324996, "log_rr": -0.376054, "p": 0.324373, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 0.686565, "se": 0.381583, "se_clustered": 0.370124, "se_greenland_robins": 0.381583, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 1.43955, "lo": 0.21444, "log_rr": -0.587697, "p": 0.226316, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.555606, "se": 0.485738, "se_clustered": 0.298735, "se_greenland_robins": 0.485738, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 3.9999, "lo": 0.250522, "log_rr": 0.00103045, "p": 0.998837, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.00103, "se": 0.706768, "se_clustered": 0.706768, "se_greenland_robins": 0.63261, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Renal failure": { "all": { "clustered_wider": false, "glp1_affected": 84, "glp1_at_risk": 93765, "hi": 1.0795, "lo": 0.603016, "log_rr": -0.214659, "p": 0.14845, "placebo_affected": 100, "placebo_at_risk": 67544, "rr": 0.806817, "se": 0.14855, "se_clustered": 0.127519, "se_greenland_robins": 0.14855, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 43, "glp1_at_risk": 47388, "hi": 1.13451, "lo": 0.508349, "log_rr": -0.275192, "p": 0.179034, "placebo_affected": 55, "placebo_at_risk": 35018, "rr": 0.759426, "se": 0.204797, "se_clustered": 0.133083, "se_greenland_robins": 0.204797, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 41, "glp1_at_risk": 46377, "hi": 1.33991, "lo": 0.557, "log_rr": -0.146296, "p": 0.513556, "placebo_affected": 45, "placebo_at_risk": 32526, "rr": 0.863902, "se": 0.22393, "se_clustered": 0.22393, "se_greenland_robins": 0.216021, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Renal impairment": { "all": { "clustered_wider": true, "glp1_affected": 74, "glp1_at_risk": 93765, "hi": 1.45786, "lo": 0.711581, "log_rr": 0.0183509, "p": 0.920111, "placebo_affected": 71, "placebo_at_risk": 67544, "rr": 1.01852, "se": 0.182971, "se_clustered": 0.182971, "se_greenland_robins": 0.167475, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 1.8669, "lo": 0.671412, "log_rr": 0.112955, "p": 0.665039, "placebo_affected": 28, "placebo_at_risk": 35018, "rr": 1.11958, "se": 0.260886, "se_clustered": 0.221824, "se_greenland_robins": 0.260886, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.922474, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 42, "glp1_at_risk": 46377, "hi": 1.60504, "lo": 0.565583, "log_rr": -0.0483745, "p": 0.855741, "placebo_affected": 43, "placebo_at_risk": 32526, "rr": 0.952777, "se": 0.266089, "se_clustered": 0.266089, "se_greenland_robins": 0.218715, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Renal neoplasm": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 2.96344, "lo": 0.683581, "log_rr": 0.352971, "p": 0.345519, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.42329, "se": 0.374181, "se_clustered": 0.31916, "se_greenland_robins": 0.374181, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 2, "glp1_at_risk": 47388, "hi": 2.73002, "lo": 0.0916478, "log_rr": -0.692747, "p": 0.423671, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 0.5002, "se": 0.865861, "se_clustered": 0.432945, "se_greenland_robins": 0.865861, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 4.36204, "lo": 0.798662, "log_rr": 0.624062, "p": 0.149617, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.86649, "se": 0.43311, "se_clustered": 0.37478, "se_greenland_robins": 0.43311, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Respiratory distress": { "all": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 3.62946, "lo": 0.250984, "log_rr": -0.0466408, "p": 0.945437, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.95443, "se": 0.681505, "se_clustered": 0.681505, "se_greenland_robins": 0.4339, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 12.9739, "lo": 0.236213, "log_rr": 0.559959, "p": 0.583737, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 1.7506, "se": 1.02195, "se_clustered": 1.02195, "se_greenland_robins": 0.626691, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.909995, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 2.62061, "lo": 0.0952123, "log_rr": -0.69412, "p": 0.411777, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.499514, "se": 0.845693, "se_clustered": 0.845693, "se_greenland_robins": 0.662491, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Respiratory failure": { "all": { "clustered_wider": false, "glp1_affected": 132, "glp1_at_risk": 93765, "hi": 1.20047, "lo": 0.741272, "log_rr": -0.0583388, "p": 0.63525, "placebo_affected": 132, "placebo_at_risk": 67544, "rr": 0.94333, "se": 0.122986, "se_clustered": 0.104021, "se_greenland_robins": 0.122986, "strata_with_events": 26, "trials": 234, "trials_with_events": 26 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 62, "glp1_at_risk": 47388, "hi": 1.2478, "lo": 0.625002, "log_rr": -0.124308, "p": 0.480943, "placebo_affected": 68, "placebo_at_risk": 35018, "rr": 0.883108, "se": 0.176377, "se_clustered": 0.0912972, "se_greenland_robins": 0.176377, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 70, "glp1_at_risk": 46377, "hi": 1.4172, "lo": 0.71311, "log_rr": 0.00528042, "p": 0.975957, "placebo_affected": 64, "placebo_at_risk": 32526, "rr": 1.00529, "se": 0.175207, "se_clustered": 0.175207, "se_greenland_robins": 0.171744, "strata_with_events": 15, "trials": 117, "trials_with_events": 15 } }, "Respiratory tract infection": { "all": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 1.18818, "lo": 0.395658, "log_rr": -0.377392, "p": 0.178521, "placebo_affected": 32, "placebo_at_risk": 67544, "rr": 0.685647, "se": 0.280522, "se_clustered": 0.280522, "se_greenland_robins": 0.275727, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 1.34603, "lo": 0.203966, "log_rr": -0.646323, "p": 0.179383, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.523969, "se": 0.481376, "se_clustered": 0.481376, "se_greenland_robins": 0.372034, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.2519, "lo": 0.431022, "log_rr": -0.0149104, "p": 0.9718, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 0.9852, "se": 0.421786, "se_clustered": 0.278957, "se_greenland_robins": 0.421786, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Retinal detachment": { "all": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 93765, "hi": 3.26392, "lo": 0.886835, "log_rr": 0.531416, "p": 0.109893, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.70134, "se": 0.33241, "se_clustered": 0.258224, "se_greenland_robins": 0.33241, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 7.42716, "lo": 0.908852, "log_rr": 0.954785, "p": 0.0748105, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 2.59811, "se": 0.535907, "se_clustered": 0.320213, "se_greenland_robins": 0.535907, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 2.89945, "lo": 0.528876, "log_rr": 0.213759, "p": 0.622398, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 1.23832, "se": 0.434069, "se_clustered": 0.363613, "se_greenland_robins": 0.434069, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Rhabdomyolysis": { "all": { "clustered_wider": true, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 3.36423, "lo": 0.540817, "log_rr": 0.299262, "p": 0.521018, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.34886, "se": 0.466303, "se_clustered": 0.466303, "se_greenland_robins": 0.347263, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 2.00863, "lo": 0.274882, "log_rr": -0.296981, "p": 0.558325, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 0.743058, "se": 0.507373, "se_clustered": 0.507373, "se_greenland_robins": 0.427831, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 27.9065, "lo": 0.943991, "log_rr": 1.63561, "p": 0.0583251, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 5.13259, "se": 0.863919, "se_clustered": 0.863919, "se_greenland_robins": 0.793817, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Rheumatoid arthritis": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 3.56444, "lo": 0.724975, "log_rr": 0.474694, "p": 0.242659, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.60752, "se": 0.406289, "se_clustered": 0.220955, "se_greenland_robins": 0.406289, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 4.30484, "lo": 0.530225, "log_rr": 0.412643, "p": 0.439885, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.51081, "se": 0.534243, "se_clustered": 0.347287, "se_greenland_robins": 0.534243, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 5.98577, "lo": 0.513211, "log_rr": 0.561158, "p": 0.370532, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 1.7527, "se": 0.626658, "se_clustered": 0.226248, "se_greenland_robins": 0.626658, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Rib fracture": { "all": { "clustered_wider": false, "glp1_affected": 72, "glp1_at_risk": 93765, "hi": 1.09823, "lo": 0.576111, "log_rr": -0.228879, "p": 0.164328, "placebo_affected": 84, "placebo_at_risk": 67544, "rr": 0.795425, "se": 0.164582, "se_clustered": 0.133548, "se_greenland_robins": 0.164582, "strata_with_events": 28, "trials": 234, "trials_with_events": 28 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 47388, "hi": 1.26791, "lo": 0.523055, "log_rr": -0.205348, "p": 0.363301, "placebo_affected": 44, "placebo_at_risk": 35018, "rr": 0.814364, "se": 0.225882, "se_clustered": 0.105585, "se_greenland_robins": 0.225882, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 35, "glp1_at_risk": 46377, "hi": 1.28888, "lo": 0.465808, "log_rr": -0.255103, "p": 0.325837, "placebo_affected": 40, "placebo_at_risk": 32526, "rr": 0.774837, "se": 0.259637, "se_clustered": 0.259637, "se_greenland_robins": 0.240319, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 } }, "Road traffic accident": { "all": { "clustered_wider": false, "glp1_affected": 92, "glp1_at_risk": 93765, "hi": 1.47096, "lo": 0.797003, "log_rr": 0.0795089, "p": 0.61104, "placebo_affected": 76, "placebo_at_risk": 67544, "rr": 1.08276, "se": 0.156332, "se_clustered": 0.131402, "se_greenland_robins": 0.156332, "strata_with_events": 27, "trials": 234, "trials_with_events": 27 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 47, "glp1_at_risk": 47388, "hi": 1.35079, "lo": 0.611126, "log_rr": -0.0958806, "p": 0.635594, "placebo_affected": 49, "placebo_at_risk": 35018, "rr": 0.908572, "se": 0.202336, "se_clustered": 0.192074, "se_greenland_robins": 0.202336, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.917467, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 45, "glp1_at_risk": 46377, "hi": 2.27406, "lo": 0.855207, "log_rr": 0.332578, "p": 0.18252, "placebo_affected": 27, "placebo_at_risk": 32526, "rr": 1.39456, "se": 0.249489, "se_clustered": 0.184205, "se_greenland_robins": 0.249489, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 } }, "Rotator cuff syndrome": { "all": { "clustered_wider": true, "glp1_affected": 61, "glp1_at_risk": 93765, "hi": 1.73672, "lo": 0.695464, "log_rr": 0.0944125, "p": 0.685924, "placebo_affected": 49, "placebo_at_risk": 67544, "rr": 1.09901, "se": 0.233468, "se_clustered": 0.233468, "se_greenland_robins": 0.196867, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 29, "glp1_at_risk": 47388, "hi": 2.67941, "lo": 0.538657, "log_rr": 0.183459, "p": 0.653958, "placebo_affected": 23, "placebo_at_risk": 35018, "rr": 1.20137, "se": 0.409261, "se_clustered": 0.409261, "se_greenland_robins": 0.284132, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.918068, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 46377, "hi": 1.72975, "lo": 0.592061, "log_rr": 0.0119157, "p": 0.96525, "placebo_affected": 26, "placebo_at_risk": 32526, "rr": 1.01199, "se": 0.273506, "se_clustered": 0.253932, "se_greenland_robins": 0.273506, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Sciatica": { "all": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 1.63851, "lo": 0.616104, "log_rr": 0.00472518, "p": 0.984892, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 1.00474, "se": 0.249527, "se_clustered": 0.188507, "se_greenland_robins": 0.249527, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 47388, "hi": 1.86489, "lo": 0.527557, "log_rr": -0.00814835, "p": 0.979819, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.991885, "se": 0.322124, "se_clustered": 0.235313, "se_greenland_robins": 0.322124, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 46377, "hi": 2.22058, "lo": 0.472964, "log_rr": 0.0245161, "p": 0.950451, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 1.02482, "se": 0.394523, "se_clustered": 0.348375, "se_greenland_robins": 0.394523, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Seizure": { "all": { "clustered_wider": true, "glp1_affected": 60, "glp1_at_risk": 93765, "hi": 1.70345, "lo": 0.761688, "log_rr": 0.130218, "p": 0.525955, "placebo_affected": 49, "placebo_at_risk": 67544, "rr": 1.13908, "se": 0.205329, "se_clustered": 0.205329, "se_greenland_robins": 0.198059, "strata_with_events": 22, "trials": 234, "trials_with_events": 22 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 2.19772, "lo": 0.751458, "log_rr": 0.25084, "p": 0.35954, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 1.2851, "se": 0.273771, "se_clustered": 0.270947, "se_greenland_robins": 0.273771, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 46377, "hi": 1.75659, "lo": 0.567898, "log_rr": -0.00121809, "p": 0.996626, "placebo_affected": 25, "placebo_at_risk": 32526, "rr": 0.998783, "se": 0.288064, "se_clustered": 0.274828, "se_greenland_robins": 0.288064, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Sepsis": { "all": { "clustered_wider": false, "glp1_affected": 255, "glp1_at_risk": 93765, "hi": 1.15131, "lo": 0.811008, "log_rr": -0.0342888, "p": 0.701264, "placebo_affected": 248, "placebo_at_risk": 67544, "rr": 0.966292, "se": 0.0893833, "se_clustered": 0.0845729, "se_greenland_robins": 0.0893833, "strata_with_events": 35, "trials": 234, "trials_with_events": 34 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 155, "glp1_at_risk": 47388, "hi": 1.36035, "lo": 0.861137, "log_rr": 0.0791218, "p": 0.49758, "placebo_affected": 139, "placebo_at_risk": 35018, "rr": 1.08234, "se": 0.116647, "se_clustered": 0.0847029, "se_greenland_robins": 0.116647, "strata_with_events": 19, "trials": 117, "trials_with_events": 18 }, "discovery_q": 0.861582, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 100, "glp1_at_risk": 46377, "hi": 1.08059, "lo": 0.624462, "log_rr": -0.196678, "p": 0.159752, "placebo_affected": 109, "placebo_at_risk": 32526, "rr": 0.821455, "se": 0.139894, "se_clustered": 0.0745455, "se_greenland_robins": 0.139894, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 } }, "Septic shock": { "all": { "clustered_wider": false, "glp1_affected": 86, "glp1_at_risk": 93765, "hi": 0.822251, "lo": 0.475335, "log_rr": -0.469723, "p": 0.000779887, "placebo_affected": 129, "placebo_at_risk": 67544, "rr": 0.625176, "se": 0.139805, "se_clustered": 0.0770931, "se_greenland_robins": 0.139805, "strata_with_events": 24, "trials": 234, "trials_with_events": 24 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 52, "glp1_at_risk": 47388, "hi": 0.963093, "lo": 0.472578, "log_rr": -0.393579, "p": 0.0302335, "placebo_affected": 74, "placebo_at_risk": 35018, "rr": 0.674638, "se": 0.181622, "se_clustered": 0.0500495, "se_greenland_robins": 0.181622, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 }, "discovery_q": 0.42757, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 0.861262, "lo": 0.364197, "log_rr": -0.579708, "p": 0.00828606, "placebo_affected": 55, "placebo_at_risk": 32526, "rr": 0.560062, "se": 0.219571, "se_clustered": 0.17907, "se_greenland_robins": 0.219571, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Shock": { "all": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 3.30929, "lo": 0.455898, "log_rr": 0.205623, "p": 0.684281, "placebo_affected": 9, "placebo_at_risk": 67544, "rr": 1.22829, "se": 0.505678, "se_clustered": 0.505678, "se_greenland_robins": 0.43159, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 4.08755, "lo": 0.526522, "log_rr": 0.383242, "p": 0.463539, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.46703, "se": 0.522818, "se_clustered": 0.522818, "se_greenland_robins": 0.46391, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 1, "glp1_at_risk": 46377, "hi": 6.30074, "lo": 0.0176111, "log_rr": -1.09928, "p": 0.463648, "placebo_affected": 2, "placebo_at_risk": 32526, "rr": 0.333111, "se": 1.5, "se_clustered": 1.5, "se_greenland_robins": 1.4726, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Sinus bradycardia": { "all": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 0.872043, "lo": 0.19954, "log_rr": -0.874328, "p": 0.0201322, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 0.417142, "se": 0.376237, "se_clustered": 0.340374, "se_greenland_robins": 0.376237, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 1.07065, "lo": 0.131707, "log_rr": -0.979455, "p": 0.0669133, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.375516, "se": 0.534562, "se_clustered": 0.534562, "se_greenland_robins": 0.47846, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.585208, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 1.66137, "lo": 0.150715, "log_rr": -0.692364, "p": 0.258124, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.500392, "se": 0.612258, "se_clustered": 0.456178, "se_greenland_robins": 0.612258, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Sinus node dysfunction": { "all": { "clustered_wider": false, "glp1_affected": 41, "glp1_at_risk": 93765, "hi": 1.05429, "lo": 0.468013, "log_rr": -0.353194, "p": 0.0882367, "placebo_affected": 56, "placebo_at_risk": 67544, "rr": 0.702441, "se": 0.20718, "se_clustered": 0.175749, "se_greenland_robins": 0.20718, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 47388, "hi": 1.07153, "lo": 0.394109, "log_rr": -0.431018, "p": 0.0911821, "placebo_affected": 38, "placebo_at_risk": 35018, "rr": 0.649847, "se": 0.255162, "se_clustered": 0.235658, "se_greenland_robins": 0.255162, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.628862, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 46377, "hi": 1.63857, "lo": 0.405278, "log_rr": -0.204679, "p": 0.565753, "placebo_affected": 18, "placebo_at_risk": 32526, "rr": 0.814909, "se": 0.356386, "se_clustered": 0.330036, "se_greenland_robins": 0.356386, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Sinusitis": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 2.46639, "lo": 0.606724, "log_rr": 0.201537, "p": 0.573223, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 1.22328, "se": 0.357771, "se_clustered": 0.347489, "se_greenland_robins": 0.357771, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 2.74371, "lo": 0.317333, "log_rr": -0.0692471, "p": 0.899861, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 0.933096, "se": 0.550295, "se_clustered": 0.550295, "se_greenland_robins": 0.487233, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.973628, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 4.6493, "lo": 0.559058, "log_rr": 0.477607, "p": 0.376778, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 1.61221, "se": 0.540372, "se_clustered": 0.540372, "se_greenland_robins": 0.533959, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Skin laceration": { "all": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 3.82368, "lo": 0.45716, "log_rr": 0.279246, "p": 0.60629, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 1.32213, "se": 0.54183, "se_clustered": 0.54183, "se_greenland_robins": 0.364257, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 6.58332, "lo": 0.986971, "log_rr": 0.935712, "p": 0.0532519, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 2.54903, "se": 0.484104, "se_clustered": 0.262381, "se_greenland_robins": 0.484104, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.575799, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 1.38899, "lo": 0.0727997, "log_rr": -1.14573, "p": 0.127721, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.317991, "se": 0.752213, "se_clustered": 0.590232, "se_greenland_robins": 0.752213, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Skin ulcer": { "all": { "clustered_wider": false, "glp1_affected": 66, "glp1_at_risk": 93765, "hi": 0.944004, "lo": 0.496506, "log_rr": -0.378892, "p": 0.0208041, "placebo_affected": 88, "placebo_at_risk": 67544, "rr": 0.68462, "se": 0.163915, "se_clustered": 0.118019, "se_greenland_robins": 0.163915, "strata_with_events": 19, "trials": 234, "trials_with_events": 19 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 0.90544, "lo": 0.37593, "log_rr": -0.538843, "p": 0.016264, "placebo_affected": 52, "placebo_at_risk": 35018, "rr": 0.583423, "se": 0.224243, "se_clustered": 0.149429, "se_greenland_robins": 0.224243, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.335688, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 1.33131, "lo": 0.515286, "log_rr": -0.188433, "p": 0.436465, "placebo_affected": 36, "placebo_at_risk": 32526, "rr": 0.828256, "se": 0.242147, "se_clustered": 0.190846, "se_greenland_robins": 0.242147, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Sleep apnoea syndrome": { "all": { "clustered_wider": true, "glp1_affected": 29, "glp1_at_risk": 93765, "hi": 1.44588, "lo": 0.345414, "log_rr": -0.347148, "p": 0.34188, "placebo_affected": 36, "placebo_at_risk": 67544, "rr": 0.706701, "se": 0.365243, "se_clustered": 0.365243, "se_greenland_robins": 0.255423, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 2.03275, "lo": 0.207025, "log_rr": -0.432765, "p": 0.457702, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 0.648713, "se": 0.582741, "se_clustered": 0.582741, "se_greenland_robins": 0.35096, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 1.88755, "lo": 0.324925, "log_rr": -0.244441, "p": 0.586029, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 0.783142, "se": 0.448845, "se_clustered": 0.448845, "se_greenland_robins": 0.372954, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Small cell lung cancer": { "all": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 93765, "hi": 2.7854, "lo": 0.841791, "log_rr": 0.426084, "p": 0.162779, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.53125, "se": 0.305264, "se_clustered": 0.165984, "se_greenland_robins": 0.305264, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 5.20783, "lo": 0.856249, "log_rr": 0.747485, "p": 0.10459, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 2.11168, "se": 0.460559, "se_clustered": 0.202345, "se_greenland_robins": 0.460559, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.58188, "lo": 0.507063, "log_rr": 0.134698, "p": 0.745635, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.14419, "se": 0.415221, "se_clustered": 0.309432, "se_greenland_robins": 0.415221, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Small cell lung cancer metastatic": { "all": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 3.8546, "lo": 0.650386, "log_rr": 0.45954, "p": 0.31139, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.58334, "se": 0.453951, "se_clustered": 0.392167, "se_greenland_robins": 0.453951, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 3.45193, "lo": 0.479022, "log_rr": 0.251463, "p": 0.617701, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.2859, "se": 0.503821, "se_clustered": 0.365864, "se_greenland_robins": 0.503821, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 53.6008, "lo": 0.250652, "log_rr": 1.29894, "p": 0.34261, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 3.6654, "se": 1.36871, "se_clustered": 1.36871, "se_greenland_robins": 1.1548, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Small intestinal obstruction": { "all": { "clustered_wider": false, "glp1_affected": 56, "glp1_at_risk": 93765, "hi": 1.45577, "lo": 0.678113, "log_rr": -0.0064516, "p": 0.973593, "placebo_affected": 53, "placebo_at_risk": 67544, "rr": 0.993569, "se": 0.194896, "se_clustered": 0.156353, "se_greenland_robins": 0.194896, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 2.17852, "lo": 0.742277, "log_rr": 0.240307, "p": 0.381629, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 1.27164, "se": 0.274668, "se_clustered": 0.194768, "se_greenland_robins": 0.274668, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 46377, "hi": 1.32985, "lo": 0.441815, "log_rr": -0.265899, "p": 0.344206, "placebo_affected": 29, "placebo_at_risk": 32526, "rr": 0.766517, "se": 0.28111, "se_clustered": 0.197994, "se_greenland_robins": 0.28111, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 } }, "Soft tissue infection": { "all": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 3.12951, "lo": 0.249322, "log_rr": -0.124068, "p": 0.847557, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 0.88332, "se": 0.645391, "se_clustered": 0.645391, "se_greenland_robins": 0.470365, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 9.42993, "lo": 0.425517, "log_rr": 0.69472, "p": 0.379434, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 2.00315, "se": 0.790407, "se_clustered": 0.790407, "se_greenland_robins": 0.707459, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 2.2391, "lo": 0.0728736, "log_rr": -0.906477, "p": 0.299533, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.403945, "se": 0.873767, "se_clustered": 0.873767, "se_greenland_robins": 0.729276, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Spinal column stenosis": { "all": { "clustered_wider": true, "glp1_affected": 29, "glp1_at_risk": 93765, "hi": 1.55778, "lo": 0.431095, "log_rr": -0.199082, "p": 0.54355, "placebo_affected": 34, "placebo_at_risk": 67544, "rr": 0.819482, "se": 0.327733, "se_clustered": 0.327733, "se_greenland_robins": 0.254339, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 1.58598, "lo": 0.29375, "log_rr": -0.38191, "p": 0.37464, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.682557, "se": 0.430168, "se_clustered": 0.171707, "se_greenland_robins": 0.430168, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 2.50273, "lo": 0.328334, "log_rr": -0.0981704, "p": 0.849729, "placebo_affected": 21, "placebo_at_risk": 32526, "rr": 0.906494, "se": 0.518149, "se_clustered": 0.518149, "se_greenland_robins": 0.316468, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Spinal compression fracture": { "all": { "clustered_wider": false, "glp1_affected": 37, "glp1_at_risk": 93765, "hi": 2.86641, "lo": 0.916668, "log_rr": 0.483026, "p": 0.0967546, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.62097, "se": 0.29084, "se_clustered": 0.250999, "se_greenland_robins": 0.29084, "strata_with_events": 25, "trials": 234, "trials_with_events": 25 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 47388, "hi": 2.25677, "lo": 0.48308, "log_rr": 0.0431806, "p": 0.912564, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 1.04413, "se": 0.393248, "se_clustered": 0.365109, "se_greenland_robins": 0.393248, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.978839, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 46377, "hi": 6.5773, "lo": 1.09746, "log_rr": 0.988309, "p": 0.0304997, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 2.68669, "se": 0.456802, "se_clustered": 0.359, "se_greenland_robins": 0.456802, "strata_with_events": 17, "trials": 117, "trials_with_events": 17 } }, "Spinal fracture": { "all": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 2.05899, "lo": 0.486693, "log_rr": 0.00104643, "p": 0.997731, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.00105, "se": 0.36795, "se_clustered": 0.241912, "se_greenland_robins": 0.36795, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 6.64558, "lo": 0.60369, "log_rr": 0.694628, "p": 0.2563, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 2.00296, "se": 0.611911, "se_clustered": 0.468125, "se_greenland_robins": 0.611911, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 1.63725, "lo": 0.238895, "log_rr": -0.469356, "p": 0.339129, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 0.625405, "se": 0.491016, "se_clustered": 0.197268, "se_greenland_robins": 0.491016, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Spinal osteoarthritis": { "all": { "clustered_wider": false, "glp1_affected": 68, "glp1_at_risk": 93765, "hi": 1.47053, "lo": 0.732735, "log_rr": 0.0373247, "p": 0.833639, "placebo_affected": 59, "placebo_at_risk": 67544, "rr": 1.03803, "se": 0.177705, "se_clustered": 0.140193, "se_greenland_robins": 0.177705, "strata_with_events": 26, "trials": 234, "trials_with_events": 26 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 47388, "hi": 2.73965, "lo": 0.875607, "log_rr": 0.437497, "p": 0.132719, "placebo_affected": 20, "placebo_at_risk": 35018, "rr": 1.54883, "se": 0.290992, "se_clustered": 0.258314, "se_greenland_robins": 0.290992, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.69175, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 46377, "hi": 1.23925, "lo": 0.505027, "log_rr": -0.234318, "p": 0.306194, "placebo_affected": 39, "placebo_at_risk": 32526, "rr": 0.79111, "se": 0.228996, "se_clustered": 0.155184, "se_greenland_robins": 0.228996, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 } }, "Spinal pain": { "all": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 2.1078, "lo": 0.516597, "log_rr": 0.0425765, "p": 0.90552, "placebo_affected": 14, "placebo_at_risk": 67544, "rr": 1.0435, "se": 0.358716, "se_clustered": 0.24971, "se_greenland_robins": 0.358716, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 7.8785, "lo": 0.472206, "log_rr": 0.656899, "p": 0.360238, "placebo_affected": 3, "placebo_at_risk": 35018, "rr": 1.9288, "se": 0.717992, "se_clustered": 0.514019, "se_greenland_robins": 0.717992, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.87859, "lo": 0.356805, "log_rr": -0.200023, "p": 0.636909, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 0.818712, "se": 0.423754, "se_clustered": 0.333064, "se_greenland_robins": 0.423754, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Spinal stenosis": { "all": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 1.86156, "lo": 0.513714, "log_rr": -0.0223381, "p": 0.945777, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.97791, "se": 0.32845, "se_clustered": 0.232427, "se_greenland_robins": 0.32845, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 2.12008, "lo": 0.523514, "log_rr": 0.0521305, "p": 0.883839, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 1.05351, "se": 0.356803, "se_clustered": 0.228092, "se_greenland_robins": 0.356803, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.970343, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 3.47191, "lo": 0.117815, "log_rr": -0.446967, "p": 0.60456, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 0.639565, "se": 0.863113, "se_clustered": 0.666613, "se_greenland_robins": 0.863113, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Spondylolisthesis": { "all": { "clustered_wider": true, "glp1_affected": 23, "glp1_at_risk": 93765, "hi": 2.43995, "lo": 0.634272, "log_rr": 0.21835, "p": 0.525231, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.24402, "se": 0.343694, "se_clustered": 0.343694, "se_greenland_robins": 0.315807, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 3.74115, "lo": 0.582262, "log_rr": 0.389279, "p": 0.412044, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.47592, "se": 0.474556, "se_clustered": 0.419959, "se_greenland_robins": 0.474556, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 3.16924, "lo": 0.369367, "log_rr": 0.0787622, "p": 0.885787, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.08195, "se": 0.548341, "se_clustered": 0.548341, "se_greenland_robins": 0.425346, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Squamous cell carcinoma": { "all": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 93765, "hi": 2.51563, "lo": 0.887758, "log_rr": 0.401734, "p": 0.130559, "placebo_affected": 24, "placebo_at_risk": 67544, "rr": 1.49441, "se": 0.265714, "se_clustered": 0.24201, "se_greenland_robins": 0.265714, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 3.45249, "lo": 0.630836, "log_rr": 0.389194, "p": 0.369441, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 1.47579, "se": 0.433632, "se_clustered": 0.196184, "se_greenland_robins": 0.433632, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 24, "glp1_at_risk": 46377, "hi": 3.198, "lo": 0.708835, "log_rr": 0.409197, "p": 0.287047, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 1.50561, "se": 0.384359, "se_clustered": 0.384359, "se_greenland_robins": 0.336234, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Squamous cell carcinoma of lung": { "all": { "clustered_wider": false, "glp1_affected": 22, "glp1_at_risk": 93765, "hi": 1.29751, "lo": 0.424182, "log_rr": -0.298572, "p": 0.295187, "placebo_affected": 29, "placebo_at_risk": 67544, "rr": 0.741877, "se": 0.28522, "se_clustered": 0.254501, "se_greenland_robins": 0.28522, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.70893, "lo": 0.374584, "log_rr": -0.223037, "p": 0.564601, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.800086, "se": 0.387203, "se_clustered": 0.359228, "se_greenland_robins": 0.387203, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.902837, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.55507, "lo": 0.29689, "log_rr": -0.386435, "p": 0.360308, "placebo_affected": 14, "placebo_at_risk": 32526, "rr": 0.679475, "se": 0.422435, "se_clustered": 0.386669, "se_greenland_robins": 0.422435, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Squamous cell carcinoma of skin": { "all": { "clustered_wider": false, "glp1_affected": 41, "glp1_at_risk": 93765, "hi": 2.07087, "lo": 0.821669, "log_rr": 0.265775, "p": 0.259726, "placebo_affected": 31, "placebo_at_risk": 67544, "rr": 1.30444, "se": 0.235817, "se_clustered": 0.16687, "se_greenland_robins": 0.235817, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 47388, "hi": 2.72265, "lo": 0.826529, "log_rr": 0.405542, "p": 0.182368, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 1.50012, "se": 0.304119, "se_clustered": 0.220365, "se_greenland_robins": 0.304119, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 2.18221, "lo": 0.497985, "log_rr": 0.0415771, "p": 0.912167, "placebo_affected": 13, "placebo_at_risk": 32526, "rr": 1.04245, "se": 0.376926, "se_clustered": 0.235163, "se_greenland_robins": 0.376926, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Staphylococcal bacteraemia": { "all": { "clustered_wider": true, "glp1_affected": 10, "glp1_at_risk": 93765, "hi": 1.37699, "lo": 0.234764, "log_rr": -0.564636, "p": 0.21089, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 0.568567, "se": 0.451303, "se_clustered": 0.451303, "se_greenland_robins": 0.404436, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 2.41244, "lo": 0.317401, "log_rr": -0.133476, "p": 0.796433, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.875049, "se": 0.517414, "se_clustered": 0.496603, "se_greenland_robins": 0.517414, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 1.20222, "lo": 0.0729357, "log_rr": -1.217, "p": 0.08869, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.296116, "se": 0.714897, "se_clustered": 0.714897, "se_greenland_robins": 0.703879, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Staphylococcal infection": { "all": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 1.89183, "lo": 0.473017, "log_rr": -0.0555397, "p": 0.875198, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.945974, "se": 0.353621, "se_clustered": 0.353621, "se_greenland_robins": 0.350319, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 2.88177, "lo": 0.347224, "log_rr": 0.000310163, "p": 0.999542, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 1.00031, "se": 0.539855, "se_clustered": 0.539855, "se_greenland_robins": 0.499936, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 2.54091, "lo": 0.315167, "log_rr": -0.111065, "p": 0.834766, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.89488, "se": 0.532452, "se_clustered": 0.532452, "se_greenland_robins": 0.49131, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Staphylococcal sepsis": { "all": { "clustered_wider": true, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.1372, "lo": 0.297603, "log_rr": -0.226249, "p": 0.652818, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.79752, "se": 0.502942, "se_clustered": 0.502942, "se_greenland_robins": 0.394134, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 26.9263, "lo": 0.232248, "log_rr": 0.916576, "p": 0.449699, "placebo_affected": 2, "placebo_at_risk": 35018, "rr": 2.50071, "se": 1.21254, "se_clustered": 1.21254, "se_greenland_robins": 0.836468, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.37254, "lo": 0.192248, "log_rr": -0.666153, "p": 0.184025, "placebo_affected": 11, "placebo_at_risk": 32526, "rr": 0.513681, "se": 0.501446, "se_clustered": 0.501446, "se_greenland_robins": 0.483386, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Stent placement": { "all": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 1.53331, "lo": 0.433394, "log_rr": -0.20434, "p": 0.526124, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 0.815185, "se": 0.322337, "se_clustered": 0.1958, "se_greenland_robins": 0.322337, "strata_with_events": 6, "trials": 234, "trials_with_events": 6 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 1.68848, "lo": 0.391003, "log_rr": -0.207606, "p": 0.578002, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.812527, "se": 0.373187, "se_clustered": 0.038066, "se_greenland_robins": 0.373187, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 }, "discovery_q": 0.909995, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 4.07375, "lo": 0.166348, "log_rr": -0.194555, "p": 0.811527, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.823201, "se": 0.815891, "se_clustered": 0.815891, "se_greenland_robins": 0.63955, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Subarachnoid haemorrhage": { "all": { "clustered_wider": true, "glp1_affected": 32, "glp1_at_risk": 93765, "hi": 1.77975, "lo": 0.579554, "log_rr": 0.015489, "p": 0.956843, "placebo_affected": 30, "placebo_at_risk": 67544, "rr": 1.01561, "se": 0.286223, "se_clustered": 0.286223, "se_greenland_robins": 0.254355, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 1.38379, "lo": 0.395225, "log_rr": -0.301736, "p": 0.345239, "placebo_affected": 23, "placebo_at_risk": 35018, "rr": 0.739534, "se": 0.319681, "se_clustered": 0.243188, "se_greenland_robins": 0.319681, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 4.49329, "lo": 0.772169, "log_rr": 0.622016, "p": 0.166212, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 1.86268, "se": 0.449278, "se_clustered": 0.375516, "se_greenland_robins": 0.449278, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Subcutaneous abscess": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 1.38311, "lo": 0.316924, "log_rr": -0.412379, "p": 0.272599, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.662073, "se": 0.375882, "se_clustered": 0.368775, "se_greenland_robins": 0.375882, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 1.94052, "lo": 0.10949, "log_rr": -0.774481, "p": 0.290962, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.460943, "se": 0.733401, "se_clustered": 0.733401, "se_greenland_robins": 0.588772, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.824414, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 2.31272, "lo": 0.327765, "log_rr": -0.138518, "p": 0.78109, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.870647, "se": 0.498448, "se_clustered": 0.344381, "se_greenland_robins": 0.498448, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Subdural haematoma": { "all": { "clustered_wider": true, "glp1_affected": 67, "glp1_at_risk": 93765, "hi": 1.7771, "lo": 0.750772, "log_rr": 0.144166, "p": 0.51191, "placebo_affected": 54, "placebo_at_risk": 67544, "rr": 1.15508, "se": 0.21981, "se_clustered": 0.21981, "se_greenland_robins": 0.180488, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 40, "glp1_at_risk": 47388, "hi": 2.76432, "lo": 0.713112, "log_rr": 0.339339, "p": 0.326223, "placebo_affected": 27, "placebo_at_risk": 35018, "rr": 1.40402, "se": 0.345647, "se_clustered": 0.345647, "se_greenland_robins": 0.251526, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.842691, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 27, "glp1_at_risk": 46377, "hi": 1.53894, "lo": 0.551476, "log_rr": -0.0820317, "p": 0.754027, "placebo_affected": 27, "placebo_at_risk": 32526, "rr": 0.921243, "se": 0.261803, "se_clustered": 0.256559, "se_greenland_robins": 0.261803, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Sudden cardiac death": { "all": { "clustered_wider": false, "glp1_affected": 39, "glp1_at_risk": 93765, "hi": 1.5138, "lo": 0.603331, "log_rr": -0.0453344, "p": 0.846818, "placebo_affected": 37, "placebo_at_risk": 67544, "rr": 0.955678, "se": 0.234675, "se_clustered": 0.174118, "se_greenland_robins": 0.234675, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 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67544, "rr": 0.697058, "se": 0.182859, "se_clustered": 0.162878, "se_greenland_robins": 0.182859, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 39, "glp1_at_risk": 47388, "hi": 1.11966, "lo": 0.467673, "log_rr": -0.323479, "p": 0.146374, "placebo_affected": 52, "placebo_at_risk": 35018, "rr": 0.723627, "se": 0.222711, "se_clustered": 0.222711, "se_greenland_robins": 0.214633, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.700059, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 46377, "hi": 1.25505, "lo": 0.318581, "log_rr": -0.458352, "p": 0.190042, "placebo_affected": 21, "placebo_at_risk": 32526, "rr": 0.632325, "se": 0.349765, "se_clustered": 0.158287, "se_greenland_robins": 0.349765, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Suicidal ideation": { "all": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 93765, "hi": 1.86199, "lo": 0.474611, "log_rr": -0.0618063, "p": 0.859317, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.940065, "se": 0.348707, "se_clustered": 0.24238, "se_greenland_robins": 0.348707, "strata_with_events": 22, "trials": 234, "trials_with_events": 22 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 2.37567, "lo": 0.376313, "log_rr": -0.0560285, "p": 0.905122, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 0.945512, "se": 0.470063, "se_clustered": 0.280365, "se_greenland_robins": 0.470063, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.975038, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 9, "glp1_at_risk": 46377, "hi": 2.58097, "lo": 0.337229, "log_rr": -0.0694143, "p": 0.89364, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.93294, "se": 0.519182, "se_clustered": 0.441274, "se_greenland_robins": 0.519182, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Suicide attempt": { "all": { "clustered_wider": true, "glp1_affected": 19, "glp1_at_risk": 93765, "hi": 1.19571, "lo": 0.349399, "log_rr": -0.436401, "p": 0.164388, "placebo_affected": 23, "placebo_at_risk": 67544, "rr": 0.646359, "se": 0.313853, "se_clustered": 0.313853, "se_greenland_robins": 0.312042, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.86123, "lo": 0.352176, "log_rr": -0.211193, "p": 0.61901, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.809618, "se": 0.424718, "se_clustered": 0.370428, "se_greenland_robins": 0.424718, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.3676, "lo": 0.178688, "log_rr": -0.70453, "p": 0.174785, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.494341, "se": 0.519187, "se_clustered": 0.519187, "se_greenland_robins": 0.467594, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 } }, "Supraventricular tachycardia": { "all": { "clustered_wider": true, "glp1_affected": 63, "glp1_at_risk": 93765, "hi": 2.15964, "lo": 0.94641, "log_rr": 0.357432, "p": 0.0894575, "placebo_affected": 40, "placebo_at_risk": 67544, "rr": 1.42965, "se": 0.210469, "se_clustered": 0.210469, "se_greenland_robins": 0.205529, "strata_with_events": 21, "trials": 234, "trials_with_events": 21 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 38, "glp1_at_risk": 47388, "hi": 2.5961, "lo": 0.896174, "log_rr": 0.422195, "p": 0.119716, "placebo_affected": 24, "placebo_at_risk": 35018, "rr": 1.52531, "se": 0.271339, "se_clustered": 0.271339, "se_greenland_robins": 0.264432, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.665905, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 25, "glp1_at_risk": 46377, "hi": 2.45502, "lo": 0.680546, "log_rr": 0.256638, "p": 0.432979, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 1.29258, "se": 0.327301, "se_clustered": 0.292086, "se_greenland_robins": 0.327301, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Syncope": { "all": { "clustered_wider": false, "glp1_affected": 267, "glp1_at_risk": 93765, "hi": 1.41573, "lo": 0.987538, "log_rr": 0.167552, "p": 0.0682294, "placebo_affected": 213, "placebo_at_risk": 67544, "rr": 1.18241, "se": 0.0918852, "se_clustered": 0.0509866, "se_greenland_robins": 0.0918852, "strata_with_events": 34, "trials": 234, "trials_with_events": 33 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 179, "glp1_at_risk": 47388, "hi": 1.50552, "lo": 0.969963, "log_rr": 0.18932, "p": 0.0914043, "placebo_affected": 143, "placebo_at_risk": 35018, "rr": 1.20843, "se": 0.112154, "se_clustered": 0.0662793, "se_greenland_robins": 0.112154, "strata_with_events": 19, "trials": 117, "trials_with_events": 18 }, "discovery_q": 0.628862, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 88, "glp1_at_risk": 46377, "hi": 1.54814, "lo": 0.825863, "log_rr": 0.122864, "p": 0.443413, "placebo_affected": 70, "placebo_at_risk": 32526, "rr": 1.13073, "se": 0.160305, "se_clustered": 0.0761489, "se_greenland_robins": 0.160305, "strata_with_events": 15, "trials": 117, "trials_with_events": 15 } }, "Synovial cyst": { "all": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 93765, "hi": 4.81534, "lo": 0.627613, "log_rr": 0.552987, "p": 0.287412, "placebo_affected": 7, "placebo_at_risk": 67544, "rr": 1.73844, "se": 0.519815, "se_clustered": 0.519815, "se_greenland_robins": 0.480067, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 71.0079, "lo": 1.05779, "log_rr": 2.15949, "p": 0.0441866, "placebo_affected": 1, "placebo_at_risk": 35018, "rr": 8.66669, "se": 1.07313, "se_clustered": 1.07313, "se_greenland_robins": 1.06845, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.512034, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 2.21902, "lo": 0.153991, "log_rr": -0.536895, "p": 0.4302, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.58456, "se": 0.680606, "se_clustered": 0.568903, "se_greenland_robins": 0.680606, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Systemic inflammatory response syndrome": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 3.49439, "lo": 0.698504, "log_rr": 0.446172, "p": 0.277333, "placebo_affected": 10, "placebo_at_risk": 67544, "rr": 1.56232, "se": 0.410715, "se_clustered": 0.37046, "se_greenland_robins": 0.410715, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 6.33394, "lo": 0.765072, "log_rr": 0.789069, "p": 0.143372, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 2.20135, "se": 0.539221, "se_clustered": 0.450541, "se_greenland_robins": 0.539221, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.700059, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.43099, "lo": 0.24849, "log_rr": -0.0797523, "p": 0.905208, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.923345, "se": 0.669707, "se_clustered": 0.532102, "se_greenland_robins": 0.669707, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Tachycardia": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 2.74504, "lo": 0.769617, "log_rr": 0.373967, "p": 0.249007, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.45349, "se": 0.324409, "se_clustered": 0.286772, "se_greenland_robins": 0.324409, "strata_with_events": 14, "trials": 234, "trials_with_events": 14 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 47388, "hi": 2.81437, "lo": 0.649206, "log_rr": 0.301366, "p": 0.420582, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 1.3517, "se": 0.374176, "se_clustered": 0.3401, "se_greenland_robins": 0.374176, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 6.56078, "lo": 0.500823, "log_rr": 0.594804, "p": 0.364771, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 1.81268, "se": 0.656291, "se_clustered": 0.59867, "se_greenland_robins": 0.656291, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Tendon rupture": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 1.44126, "lo": 0.456759, "log_rr": -0.209041, "p": 0.47579, "placebo_affected": 26, "placebo_at_risk": 67544, "rr": 0.811362, "se": 0.293148, "se_clustered": 0.177381, "se_greenland_robins": 0.293148, "strata_with_events": 16, "trials": 234, "trials_with_events": 16 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.34575, "lo": 0.296735, "log_rr": -0.458983, "p": 0.234031, "placebo_affected": 17, "placebo_at_risk": 35018, "rr": 0.631926, "se": 0.385687, "se_clustered": 0.257238, "se_greenland_robins": 0.385687, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.8691, "lo": 0.466808, "log_rr": 0.146081, "p": 0.752495, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 1.15729, "se": 0.463232, "se_clustered": 0.169162, "se_greenland_robins": 0.463232, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Thoracic vertebral fracture": { "all": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 2.16766, "lo": 0.520927, "log_rr": 0.0607505, "p": 0.867353, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 1.06263, "se": 0.363729, "se_clustered": 0.257562, "se_greenland_robins": 0.363729, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 47388, "hi": 3.6558, "lo": 0.513902, "log_rr": 0.315297, "p": 0.528742, "placebo_affected": 7, "placebo_at_risk": 35018, "rr": 1.37067, "se": 0.500529, "se_clustered": 0.20229, "se_greenland_robins": 0.500529, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.87972, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 2.2851, "lo": 0.275071, "log_rr": -0.232158, "p": 0.667307, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 0.792821, "se": 0.540095, "se_clustered": 0.514249, "se_greenland_robins": 0.540095, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Thrombocytopenia": { "all": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 3.27243, "lo": 0.739075, "log_rr": 0.441588, "p": 0.244672, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.55517, "se": 0.37957, "se_clustered": 0.338345, "se_greenland_robins": 0.37957, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 11, "glp1_at_risk": 47388, "hi": 4.98739, "lo": 0.673999, "log_rr": 0.606193, "p": 0.235124, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.83344, "se": 0.51058, "se_clustered": 0.51058, "se_greenland_robins": 0.507444, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 3.85063, "lo": 0.400346, "log_rr": 0.216406, "p": 0.70785, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 1.24161, "se": 0.577476, "se_clustered": 0.430745, "se_greenland_robins": 0.577476, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Thyroid cancer": { "all": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 93765, "hi": 3.31932, "lo": 0.784905, "log_rr": 0.478783, "p": 0.193065, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.61411, "se": 0.367852, "se_clustered": 0.303042, "se_greenland_robins": 0.367852, "strata_with_events": 11, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 4, "glp1_at_risk": 47388, "hi": 4.24411, "lo": 0.0879695, "log_rr": -0.492616, "p": 0.618371, "placebo_affected": 4, "placebo_at_risk": 35018, "rr": 0.611026, "se": 0.988869, "se_clustered": 0.988869, "se_greenland_robins": 0.70303, "strata_with_events": 7, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 5.67465, "lo": 0.946714, "log_rr": 0.840625, "p": 0.0657535, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 2.31782, "se": 0.456837, "se_clustered": 0.180275, "se_greenland_robins": 0.456837, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Tibia fracture": { "all": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 93765, "hi": 1.19633, "lo": 0.46227, "log_rr": -0.296175, "p": 0.222095, "placebo_affected": 40, "placebo_at_risk": 67544, "rr": 0.743658, "se": 0.242572, "se_clustered": 0.218318, "se_greenland_robins": 0.242572, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 1.48148, "lo": 0.295384, "log_rr": -0.413219, "p": 0.315133, "placebo_affected": 17, "placebo_at_risk": 35018, "rr": 0.661517, "se": 0.411364, "se_clustered": 0.411364, "se_greenland_robins": 0.393937, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.830203, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 21, "glp1_at_risk": 46377, "hi": 1.46848, "lo": 0.438772, "log_rr": -0.219774, "p": 0.475747, "placebo_affected": 23, "placebo_at_risk": 32526, "rr": 0.8027, "se": 0.308169, "se_clustered": 0.229681, "se_greenland_robins": 0.308169, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Toxicity to various agents": { "all": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 93765, "hi": 2.02688, "lo": 0.438463, "log_rr": -0.058992, "p": 0.879941, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.942714, "se": 0.390562, "se_clustered": 0.390562, "se_greenland_robins": 0.338028, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 47388, "hi": 3.22229, "lo": 0.311073, "log_rr": 0.00118238, "p": 0.998418, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 1.00118, "se": 0.596393, "se_clustered": 0.596393, "se_greenland_robins": 0.471072, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 2.6456, "lo": 0.295631, "log_rr": -0.122873, "p": 0.826044, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.884376, "se": 0.559076, "se_clustered": 0.559076, "se_greenland_robins": 0.485814, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Transient ischaemic attack": { "all": { "clustered_wider": false, "glp1_affected": 233, "glp1_at_risk": 93765, "hi": 1.04332, "lo": 0.725375, "log_rr": -0.139328, "p": 0.132943, "placebo_affected": 246, "placebo_at_risk": 67544, "rr": 0.869942, "se": 0.0927249, "se_clustered": 0.0779019, "se_greenland_robins": 0.0927249, "strata_with_events": 48, "trials": 234, "trials_with_events": 48 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 158, "glp1_at_risk": 47388, "hi": 1.01591, "lo": 0.660641, "log_rr": -0.199382, "p": 0.0693377, "placebo_affected": 183, "placebo_at_risk": 35018, "rr": 0.819237, "se": 0.109779, "se_clustered": 0.0872788, "se_greenland_robins": 0.109779, "strata_with_events": 25, "trials": 117, "trials_with_events": 25 }, "discovery_q": 0.585496, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 75, "glp1_at_risk": 46377, "hi": 1.42294, "lo": 0.719669, "log_rr": 0.0118795, "p": 0.945538, "placebo_affected": 63, "placebo_at_risk": 32526, "rr": 1.01195, "se": 0.173903, "se_clustered": 0.0958356, "se_greenland_robins": 0.173903, "strata_with_events": 23, "trials": 117, "trials_with_events": 23 } }, "Transitional cell carcinoma": { "all": { "clustered_wider": true, "glp1_affected": 48, "glp1_at_risk": 93765, "hi": 3.03548, "lo": 0.914957, "log_rr": 0.510745, "p": 0.0950282, "placebo_affected": 28, "placebo_at_risk": 67544, "rr": 1.66653, "se": 0.305936, "se_clustered": 0.305936, "se_greenland_robins": 0.236379, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 47388, "hi": 5.00432, "lo": 1.31534, "log_rr": 0.942198, "p": 0.00570883, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 2.56561, "se": 0.340875, "se_clustered": 0.338054, "se_greenland_robins": 0.340875, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 }, "discovery_q": 0.24548, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 17, "glp1_at_risk": 46377, "hi": 1.99973, "lo": 0.512128, "log_rr": 0.0119157, "p": 0.972646, "placebo_affected": 16, "placebo_at_risk": 32526, "rr": 1.01199, "se": 0.347504, "se_clustered": 0.347504, "se_greenland_robins": 0.344423, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Troponin increased": { "all": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 2.10813, "lo": 0.20781, "log_rr": -0.412665, "p": 0.485071, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 0.661884, "se": 0.591066, "se_clustered": 0.591066, "se_greenland_robins": 0.451399, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 47388, "hi": 9.07077, "lo": 0.0396893, "log_rr": -0.510808, "p": 0.712399, "placebo_affected": 5, "placebo_at_risk": 35018, "rr": 0.60001, "se": 1.38567, "se_clustered": 1.38567, "se_greenland_robins": 0.730303, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.22076, "lo": 0.223214, "log_rr": -0.350887, "p": 0.549386, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.704063, "se": 0.5861, "se_clustered": 0.5861, "se_greenland_robins": 0.574904, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Type 2 diabetes mellitus": { "all": { "clustered_wider": true, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 1.48065, "lo": 0.243714, "log_rr": -0.509638, "p": 0.268186, "placebo_affected": 27, "placebo_at_risk": 67544, "rr": 0.600713, "se": 0.460274, "se_clustered": 0.460274, "se_greenland_robins": 0.310107, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 13, "glp1_at_risk": 47388, "hi": 2.54941, "lo": 0.163533, "log_rr": -0.437438, "p": 0.532426, "placebo_affected": 18, "placebo_at_risk": 35018, "rr": 0.645689, "se": 0.700677, "se_clustered": 0.700677, "se_greenland_robins": 0.381612, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.88055, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 46377, "hi": 1.47117, "lo": 0.181679, "log_rr": -0.659726, "p": 0.2163, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.516993, "se": 0.533574, "se_clustered": 0.460563, "se_greenland_robins": 0.533574, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Ulna fracture": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 2.01396, "lo": 0.408189, "log_rr": -0.0979612, "p": 0.809879, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 0.906684, "se": 0.407183, "se_clustered": 0.37516, "se_greenland_robins": 0.407183, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 2.66804, "lo": 0.273504, "log_rr": -0.157547, "p": 0.786292, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.854237, "se": 0.581078, "se_clustered": 0.384305, "se_greenland_robins": 0.581078, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 3.81673, "lo": 0.243857, "log_rr": -0.0358897, "p": 0.959208, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 0.964747, "se": 0.701689, "se_clustered": 0.701689, "se_greenland_robins": 0.570417, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Umbilical hernia": { "all": { "clustered_wider": true, "glp1_affected": 43, "glp1_at_risk": 93765, "hi": 1.38711, "lo": 0.482668, "log_rr": -0.200601, "p": 0.456339, "placebo_affected": 47, "placebo_at_risk": 67544, "rr": 0.818239, "se": 0.269303, "se_clustered": 0.269303, "se_greenland_robins": 0.213716, "strata_with_events": 24, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 47388, "hi": 2.44145, "lo": 0.784861, "log_rr": 0.325171, "p": 0.261355, "placebo_affected": 20, "placebo_at_risk": 35018, "rr": 1.38427, "se": 0.289505, "se_clustered": 0.282178, "se_greenland_robins": 0.289505, "strata_with_events": 15, "trials": 117, "trials_with_events": 14 }, "discovery_q": 0.82326, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 0.791134, "lo": 0.198238, "log_rr": -0.926287, "p": 0.00870208, "placebo_affected": 27, "placebo_at_risk": 32526, "rr": 0.396021, "se": 0.353067, "se_clustered": 0.174304, "se_greenland_robins": 0.353067, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Upper gastrointestinal haemorrhage": { "all": { "clustered_wider": false, "glp1_affected": 61, "glp1_at_risk": 93765, "hi": 1.31179, "lo": 0.646646, "log_rr": -0.0822808, "p": 0.648408, "placebo_affected": 64, "placebo_at_risk": 67544, "rr": 0.921013, "se": 0.18045, "se_clustered": 0.0781889, "se_greenland_robins": 0.18045, "strata_with_events": 17, "trials": 234, "trials_with_events": 17 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 32, "glp1_at_risk": 47388, "hi": 1.4165, "lo": 0.538781, "log_rr": -0.135129, "p": 0.583705, "placebo_affected": 35, "placebo_at_risk": 35018, "rr": 0.873603, "se": 0.246595, "se_clustered": 0.0860032, "se_greenland_robins": 0.246595, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 }, "discovery_q": 0.909995, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 46377, "hi": 1.64535, "lo": 0.582287, "log_rr": -0.0214196, "p": 0.935576, "placebo_affected": 29, "placebo_at_risk": 32526, "rr": 0.978808, "se": 0.264991, "se_clustered": 0.148097, "se_greenland_robins": 0.264991, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Upper limb fracture": { "all": { "clustered_wider": true, "glp1_affected": 26, "glp1_at_risk": 93765, "hi": 2.76101, "lo": 0.733468, "log_rr": 0.352812, "p": 0.296797, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 1.42306, "se": 0.338161, "se_clustered": 0.338161, "se_greenland_robins": 0.315054, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 5.04885, "lo": 0.177503, "log_rr": -0.0548043, "p": 0.948837, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.94667, "se": 0.85408, "se_clustered": 0.85408, "se_greenland_robins": 0.559023, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 20, "glp1_at_risk": 46377, "hi": 3.63938, "lo": 0.800602, "log_rr": 0.534711, "p": 0.166284, "placebo_affected": 10, "placebo_at_risk": 32526, "rr": 1.70695, "se": 0.386283, "se_clustered": 0.30401, "se_greenland_robins": 0.386283, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Upper respiratory tract infection": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 1.35902, "lo": 0.445857, "log_rr": -0.250495, "p": 0.378305, "placebo_affected": 27, "placebo_at_risk": 67544, "rr": 0.778415, "se": 0.284322, "se_clustered": 0.210483, "se_greenland_robins": 0.284322, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 47388, "hi": 2.31555, "lo": 0.504514, "log_rr": 0.077745, "p": 0.841484, "placebo_affected": 12, "placebo_at_risk": 35018, "rr": 1.08085, "se": 0.388734, "se_clustered": 0.171642, "se_greenland_robins": 0.388734, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.956127, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 1.24417, "lo": 0.230096, "log_rr": -0.625396, "p": 0.146349, "placebo_affected": 15, "placebo_at_risk": 32526, "rr": 0.535049, "se": 0.430551, "se_clustered": 0.319828, "se_greenland_robins": 0.430551, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 } }, "Ureterolithiasis": { "all": { "clustered_wider": true, "glp1_affected": 69, "glp1_at_risk": 93765, "hi": 1.91179, "lo": 0.801507, "log_rr": 0.213389, "p": 0.335934, "placebo_affected": 48, "placebo_at_risk": 67544, "rr": 1.23787, "se": 0.221765, "se_clustered": 0.221765, "se_greenland_robins": 0.189568, "strata_with_events": 25, "trials": 234, "trials_with_events": 25 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 38, "glp1_at_risk": 47388, "hi": 2.66668, "lo": 0.66693, "log_rr": 0.287882, "p": 0.4155, "placebo_affected": 25, "placebo_at_risk": 35018, "rr": 1.3336, "se": 0.353554, "se_clustered": 0.353554, "se_greenland_robins": 0.266164, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 31, "glp1_at_risk": 46377, "hi": 1.93741, "lo": 0.671749, "log_rr": 0.131742, "p": 0.625873, "placebo_affected": 23, "placebo_at_risk": 32526, "rr": 1.14081, "se": 0.270215, "se_clustered": 0.257734, "se_greenland_robins": 0.270215, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Urethral stenosis": { "all": { "clustered_wider": false, "glp1_affected": 24, "glp1_at_risk": 93765, "hi": 2.03156, "lo": 0.625932, "log_rr": 0.120145, "p": 0.689135, "placebo_affected": 21, "placebo_at_risk": 67544, "rr": 1.12766, "se": 0.300342, "se_clustered": 0.226001, "se_greenland_robins": 0.300342, "strata_with_events": 11, "trials": 234, "trials_with_events": 11 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 2.02302, "lo": 0.421428, "log_rr": -0.0797576, "p": 0.842027, "placebo_affected": 13, "placebo_at_risk": 35018, "rr": 0.92334, "se": 0.400185, "se_clustered": 0.271109, "se_greenland_robins": 0.400185, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.956127, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 3.60356, "lo": 0.591075, "log_rr": 0.378056, "p": 0.41234, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.45944, "se": 0.461165, "se_clustered": 0.393576, "se_greenland_robins": 0.461165, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Urinary incontinence": { "all": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 93765, "hi": 1.39504, "lo": 0.172377, "log_rr": -0.712576, "p": 0.181599, "placebo_affected": 16, "placebo_at_risk": 67544, "rr": 0.490379, "se": 0.533426, "se_clustered": 0.533426, "se_greenland_robins": 0.427217, "strata_with_events": 10, "trials": 234, "trials_with_events": 10 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 1.99446, "lo": 0.117574, "log_rr": -0.725156, "p": 0.315348, "placebo_affected": 10, "placebo_at_risk": 35018, "rr": 0.484249, "se": 0.722221, "se_clustered": 0.722221, "se_greenland_robins": 0.536292, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.830203, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 3, "glp1_at_risk": 46377, "hi": 2.9409, "lo": 0.0853297, "log_rr": -0.691258, "p": 0.443999, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.500946, "se": 0.903065, "se_clustered": 0.903065, "se_greenland_robins": 0.706672, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Urinary retention": { "all": { "clustered_wider": true, "glp1_affected": 54, "glp1_at_risk": 93765, "hi": 1.69814, "lo": 0.645812, "log_rr": 0.0461439, "p": 0.851586, "placebo_affected": 49, "placebo_at_risk": 67544, "rr": 1.04723, "se": 0.246633, "se_clustered": 0.246633, "se_greenland_robins": 0.197281, "strata_with_events": 18, "trials": 234, "trials_with_events": 18 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 34, "glp1_at_risk": 47388, "hi": 1.70367, "lo": 0.638461, "log_rr": 0.0420462, "p": 0.86664, "placebo_affected": 31, "placebo_at_risk": 35018, "rr": 1.04294, "se": 0.250383, "se_clustered": 0.210674, "se_greenland_robins": 0.250383, "strata_with_events": 10, "trials": 117, "trials_with_events": 10 }, "discovery_q": 0.959627, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 20, "glp1_at_risk": 46377, "hi": 3.31831, "lo": 0.335049, "log_rr": 0.0529893, "p": 0.927819, "placebo_affected": 18, "placebo_at_risk": 32526, "rr": 1.05442, "se": 0.584943, "se_clustered": 0.584943, "se_greenland_robins": 0.320335, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Urinary tract infection": { "all": { "clustered_wider": false, "glp1_affected": 332, "glp1_at_risk": 93765, "hi": 1.06537, "lo": 0.786025, "log_rr": -0.088722, "p": 0.252751, "placebo_affected": 344, "placebo_at_risk": 67544, "rr": 0.9151, "se": 0.077575, "se_clustered": 0.0768264, "se_greenland_robins": 0.077575, "strata_with_events": 38, "trials": 234, "trials_with_events": 38 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 189, "glp1_at_risk": 47388, "hi": 1.07048, "lo": 0.703446, "log_rr": -0.141831, "p": 0.185454, "placebo_affected": 208, "placebo_at_risk": 35018, "rr": 0.867768, "se": 0.107111, "se_clustered": 0.107111, "se_greenland_robins": 0.101488, "strata_with_events": 22, "trials": 117, "trials_with_events": 22 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 143, "glp1_at_risk": 46377, "hi": 1.24937, "lo": 0.779154, "log_rr": -0.0134551, "p": 0.911061, "placebo_affected": 136, "placebo_at_risk": 32526, "rr": 0.986635, "se": 0.120457, "se_clustered": 0.069947, "se_greenland_robins": 0.120457, "strata_with_events": 16, "trials": 117, "trials_with_events": 16 } }, "Urosepsis": { "all": { "clustered_wider": false, "glp1_affected": 91, "glp1_at_risk": 93765, "hi": 1.21312, "lo": 0.67856, "log_rr": -0.0972923, "p": 0.51154, "placebo_affected": 96, "placebo_at_risk": 67544, "rr": 0.907291, "se": 0.148212, "se_clustered": 0.134702, "se_greenland_robins": 0.148212, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 51, "glp1_at_risk": 47388, "hi": 1.1593, "lo": 0.542792, "log_rr": -0.231606, "p": 0.231544, "placebo_affected": 61, "placebo_at_risk": 35018, "rr": 0.793259, "se": 0.193587, "se_clustered": 0.151464, "se_greenland_robins": 0.193587, "strata_with_events": 12, "trials": 117, "trials_with_events": 12 }, "discovery_q": 0.813207, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 40, "glp1_at_risk": 46377, "hi": 1.74056, "lo": 0.700417, "log_rr": 0.0990638, "p": 0.669675, "placebo_affected": 35, "placebo_at_risk": 32526, "rr": 1.10414, "se": 0.23222, "se_clustered": 0.123265, "se_greenland_robins": 0.23222, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Uterine cancer": { "all": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 93765, "hi": 3.33442, "lo": 0.502512, "log_rr": 0.258082, "p": 0.592939, "placebo_affected": 8, "placebo_at_risk": 67544, "rr": 1.29444, "se": 0.482773, "se_clustered": 0.464817, "se_greenland_robins": 0.482773, "strata_with_events": 8, "trials": 234, "trials_with_events": 8 }, "discovered": false, "discovery": { "glp1_affected": 1, "glp1_at_risk": 47388, "hi": null, "lo": null, "p": null, "placebo_affected": 0, "placebo_at_risk": 35018, "rr": null, "se": null, "strata_with_events": 1, "trials": 117, "trials_with_events": 1 }, "discovery_q": null, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 46377, "hi": 3.08276, "lo": 0.443554, "log_rr": 0.156445, "p": 0.751766, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.16935, "se": 0.494591, "se_clustered": 0.472563, "se_greenland_robins": 0.494591, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Uterine leiomyoma": { "all": { "clustered_wider": false, "glp1_affected": 35, "glp1_at_risk": 93765, "hi": 2.47756, "lo": 0.762943, "log_rr": 0.31835, "p": 0.289379, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 1.37486, "se": 0.300476, "se_clustered": 0.249807, "se_greenland_robins": 0.300476, "strata_with_events": 27, "trials": 234, "trials_with_events": 27 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 47388, "hi": 2.73018, "lo": 0.499767, "log_rr": 0.155377, "p": 0.719819, "placebo_affected": 9, "placebo_at_risk": 35018, "rr": 1.1681, "se": 0.433166, "se_clustered": 0.401009, "se_greenland_robins": 0.433166, "strata_with_events": 13, "trials": 117, "trials_with_events": 13 }, "discovery_q": 0.931196, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 19, "glp1_at_risk": 46377, "hi": 3.65086, "lo": 0.704546, "log_rr": 0.47238, "p": 0.26036, "placebo_affected": 8, "placebo_at_risk": 32526, "rr": 1.60381, "se": 0.419692, "se_clustered": 0.298794, "se_greenland_robins": 0.419692, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 } }, "Uterine polyp": { "all": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 1.39388, "lo": 0.279174, "log_rr": -0.471917, "p": 0.249973, "placebo_affected": 18, "placebo_at_risk": 67544, "rr": 0.623805, "se": 0.410214, "se_clustered": 0.410214, "se_greenland_robins": 0.379235, "strata_with_events": 16, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 1.6602, "lo": 0.169962, "log_rr": -0.632623, "p": 0.276565, "placebo_affected": 11, "placebo_at_risk": 35018, "rr": 0.531197, "se": 0.581418, "se_clustered": 0.581418, "se_greenland_robins": 0.522581, "strata_with_events": 7, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.823781, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 2.26668, "lo": 0.254621, "log_rr": -0.274831, "p": 0.622183, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.759701, "se": 0.557739, "se_clustered": 0.557739, "se_greenland_robins": 0.55479, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Uterine prolapse": { "all": { "clustered_wider": true, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 13.3825, "lo": 0.994908, "log_rr": 1.29442, "p": 0.0509068, "placebo_affected": 4, "placebo_at_risk": 67544, "rr": 3.64888, "se": 0.663036, "se_clustered": 0.663036, "se_greenland_robins": 0.575187, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 81.8481, "lo": 0.628351, "log_rr": 1.9701, "p": 0.112758, "placebo_affected": 1, "placebo_at_risk": 35018, "rr": 7.17142, "se": 1.24225, "se_clustered": 1.24225, "se_greenland_robins": 1.09797, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.660557, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 8, "glp1_at_risk": 46377, "hi": 11.724, "lo": 0.52186, "log_rr": 0.905641, "p": 0.253969, "placebo_affected": 3, "placebo_at_risk": 32526, "rr": 2.47352, "se": 0.793891, "se_clustered": 0.793891, "se_greenland_robins": 0.692055, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Varicose vein": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 1.65929, "lo": 0.403335, "log_rr": -0.200797, "p": 0.577865, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.818078, "se": 0.360818, "se_clustered": 0.266895, "se_greenland_robins": 0.360818, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 2.79866, "lo": 0.370174, "log_rr": 0.0176787, "p": 0.972672, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.01784, "se": 0.516061, "se_clustered": 0.4731, "se_greenland_robins": 0.516061, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 46377, "hi": 1.81988, "lo": 0.246972, "log_rr": -0.399855, "p": 0.432583, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.670417, "se": 0.509512, "se_clustered": 0.275702, "se_greenland_robins": 0.509512, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Vascular dementia": { "all": { "clustered_wider": true, "glp1_affected": 9, "glp1_at_risk": 93765, "hi": 1.51258, "lo": 0.238342, "log_rr": -0.510116, "p": 0.279198, "placebo_affected": 15, "placebo_at_risk": 67544, "rr": 0.600426, "se": 0.471403, "se_clustered": 0.471403, "se_greenland_robins": 0.4216, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 7, "glp1_at_risk": 47388, "hi": 3.47149, "lo": 0.392202, "log_rr": 0.154303, "p": 0.781484, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.16684, "se": 0.556276, "se_clustered": 0.423982, "se_greenland_robins": 0.556276, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.93507, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 1.02973, "lo": 0.048135, "log_rr": -1.50223, "p": 0.0545463, "placebo_affected": 9, "placebo_at_risk": 32526, "rr": 0.222634, "se": 0.781403, "se_clustered": 0.536461, "se_greenland_robins": 0.781403, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Vascular graft occlusion": { "all": { "clustered_wider": false, "glp1_affected": 14, "glp1_at_risk": 93765, "hi": 1.67054, "lo": 0.406121, "log_rr": -0.193977, "p": 0.590817, "placebo_affected": 17, "placebo_at_risk": 67544, "rr": 0.823677, "se": 0.360785, "se_clustered": 0.202958, "se_greenland_robins": 0.360785, "strata_with_events": 6, "trials": 234, "trials_with_events": 6 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.58513, "lo": 0.354964, "log_rr": -0.287537, "p": 0.451316, "placebo_affected": 16, "placebo_at_risk": 35018, "rr": 0.750108, "se": 0.381743, "se_clustered": 0.190589, "se_greenland_robins": 0.381743, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 2, "glp1_at_risk": 46377, "hi": 37.8486, "lo": 0.10579, "log_rr": 0.693648, "p": 0.643772, "placebo_affected": 1, "placebo_at_risk": 32526, "rr": 2.001, "se": 1.5, "se_clustered": 1.5, "se_greenland_robins": 1.22481, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Vascular pseudoaneurysm": { "all": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 93765, "hi": 3.0312, "lo": 0.688312, "log_rr": 0.367723, "p": 0.330888, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.44444, "se": 0.378189, "se_clustered": 0.329421, "se_greenland_robins": 0.378189, "strata_with_events": 12, "trials": 234, "trials_with_events": 12 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 8, "glp1_at_risk": 47388, "hi": 2.59954, "lo": 0.353779, "log_rr": -0.0418746, "p": 0.934406, "placebo_affected": 8, "placebo_at_risk": 35018, "rr": 0.95899, "se": 0.508789, "se_clustered": 0.430236, "se_greenland_robins": 0.508789, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 }, "discovery_q": 0.992086, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 7.80782, "lo": 0.746535, "log_rr": 0.881407, "p": 0.141065, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 2.41429, "se": 0.598847, "se_clustered": 0.575721, "se_greenland_robins": 0.598847, "strata_with_events": 6, "trials": 117, "trials_with_events": 6 } }, "Vascular stent stenosis": { "all": { "clustered_wider": false, "glp1_affected": 33, "glp1_at_risk": 93765, "hi": 1.55311, "lo": 0.594069, "log_rr": -0.0402503, "p": 0.869591, "placebo_affected": 34, "placebo_at_risk": 67544, "rr": 0.960549, "se": 0.245162, "se_clustered": 0.103281, "se_greenland_robins": 0.245162, "strata_with_events": 6, "trials": 234, "trials_with_events": 6 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 29, "glp1_at_risk": 47388, "hi": 1.60926, "lo": 0.580476, "log_rr": -0.0340673, "p": 0.895804, "placebo_affected": 30, "placebo_at_risk": 35018, "rr": 0.966506, "se": 0.260127, "se_clustered": 0.117152, "se_greenland_robins": 0.260127, "strata_with_events": 2, "trials": 117, "trials_with_events": 2 }, "discovery_q": 0.973628, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 3.85513, "lo": 0.217589, "log_rr": -0.0878713, "p": 0.90462, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 0.915879, "se": 0.733317, "se_clustered": 0.588145, "se_greenland_robins": 0.733317, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 } }, "Ventricular arrhythmia": { "all": { "clustered_wider": false, "glp1_affected": 16, "glp1_at_risk": 93765, "hi": 2.67055, "lo": 0.60449, "log_rr": 0.239458, "p": 0.527508, "placebo_affected": 12, "placebo_at_risk": 67544, "rr": 1.27056, "se": 0.379001, "se_clustered": 0.336298, "se_greenland_robins": 0.379001, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 5.23739, "lo": 0.722507, "log_rr": 0.665398, "p": 0.187918, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 1.94526, "se": 0.505328, "se_clustered": 0.482379, "se_greenland_robins": 0.505328, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.729065, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 4, "glp1_at_risk": 46377, "hi": 2.14774, "lo": 0.18567, "log_rr": -0.459685, "p": 0.461717, "placebo_affected": 6, "placebo_at_risk": 32526, "rr": 0.631483, "se": 0.624552, "se_clustered": 0.466326, "se_greenland_robins": 0.624552, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Ventricular extrasystoles": { "all": { "clustered_wider": false, "glp1_affected": 38, "glp1_at_risk": 93765, "hi": 2.39302, "lo": 0.851619, "log_rr": 0.35597, "p": 0.176832, "placebo_affected": 25, "placebo_at_risk": 67544, "rr": 1.42756, "se": 0.263569, "se_clustered": 0.140241, "se_greenland_robins": 0.263569, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 28, "glp1_at_risk": 47388, "hi": 2.27181, "lo": 0.720087, "log_rr": 0.246097, "p": 0.401125, "placebo_affected": 21, "placebo_at_risk": 35018, "rr": 1.27902, "se": 0.293108, "se_clustered": 0.112377, "se_greenland_robins": 0.293108, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.844818, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 10, "glp1_at_risk": 46377, "hi": 7.42326, "lo": 0.656402, "log_rr": 0.791818, "p": 0.200676, "placebo_affected": 4, "placebo_at_risk": 32526, "rr": 2.20741, "se": 0.618787, "se_clustered": 0.525779, "se_greenland_robins": 0.618787, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 } }, "Ventricular fibrillation": { "all": { "clustered_wider": false, "glp1_affected": 30, "glp1_at_risk": 93765, "hi": 1.19546, "lo": 0.446374, "log_rr": -0.314031, "p": 0.211461, "placebo_affected": 38, "placebo_at_risk": 67544, "rr": 0.730496, "se": 0.251314, "se_clustered": 0.215387, "se_greenland_robins": 0.251314, "strata_with_events": 13, "trials": 234, "trials_with_events": 13 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 18, "glp1_at_risk": 47388, "hi": 1.17522, "lo": 0.338134, "log_rr": -0.461427, "p": 0.146524, "placebo_affected": 26, "placebo_at_risk": 35018, "rr": 0.630383, "se": 0.317805, "se_clustered": 0.262968, "se_greenland_robins": 0.317805, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 }, "discovery_q": 0.700059, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 46377, "hi": 2.14011, "lo": 0.41942, "log_rr": -0.054013, "p": 0.896634, "placebo_affected": 12, "placebo_at_risk": 32526, "rr": 0.94742, "se": 0.415758, "se_clustered": 0.258828, "se_greenland_robins": 0.415758, "strata_with_events": 5, "trials": 117, "trials_with_events": 5 } }, "Ventricular tachycardia": { "all": { "clustered_wider": true, "glp1_affected": 111, "glp1_at_risk": 93765, "hi": 1.38365, "lo": 0.780768, "log_rr": 0.0386223, "p": 0.791327, "placebo_affected": 101, "placebo_at_risk": 67544, "rr": 1.03938, "se": 0.145972, "se_clustered": 0.145972, "se_greenland_robins": 0.136908, "strata_with_events": 20, "trials": 234, "trials_with_events": 20 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 80, "glp1_at_risk": 47388, "hi": 1.41048, "lo": 0.721456, "log_rr": 0.00872231, "p": 0.959326, "placebo_affected": 78, "placebo_at_risk": 35018, "rr": 1.00876, "se": 0.171026, "se_clustered": 0.171026, "se_greenland_robins": 0.15888, "strata_with_events": 11, "trials": 117, "trials_with_events": 11 }, "discovery_q": 0.999955, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 31, "glp1_at_risk": 46377, "hi": 1.99856, "lo": 0.644912, "log_rr": 0.126892, "p": 0.660104, "placebo_affected": 23, "placebo_at_risk": 32526, "rr": 1.13529, "se": 0.288543, "se_clustered": 0.288543, "se_greenland_robins": 0.270117, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Vertebrobasilar insufficiency": { "all": { "clustered_wider": false, "glp1_affected": 11, "glp1_at_risk": 93765, "hi": 1.8067, "lo": 0.349834, "log_rr": -0.229398, "p": 0.583893, "placebo_affected": 13, "placebo_at_risk": 67544, "rr": 0.795012, "se": 0.418834, "se_clustered": 0.288837, "se_greenland_robins": 0.418834, "strata_with_events": 7, "trials": 234, "trials_with_events": 7 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 5, "glp1_at_risk": 47388, "hi": 2.51378, "lo": 0.206571, "log_rr": -0.327663, "p": 0.607257, "placebo_affected": 6, "placebo_at_risk": 35018, "rr": 0.720606, "se": 0.637486, "se_clustered": 0.560201, "se_greenland_robins": 0.637486, "strata_with_events": 4, "trials": 117, "trials_with_events": 4 }, "discovery_q": 0.912598, "replicated": false, "replication": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 46377, "hi": 2.5557, "lo": 0.288622, "log_rr": -0.152154, "p": 0.78449, "placebo_affected": 7, "placebo_at_risk": 32526, "rr": 0.858856, "se": 0.556378, "se_clustered": 0.376797, "se_greenland_robins": 0.556378, "strata_with_events": 3, "trials": 117, "trials_with_events": 3 } }, "Vertigo": { "all": { "clustered_wider": true, "glp1_affected": 66, "glp1_at_risk": 93765, "hi": 1.98135, "lo": 0.715673, "log_rr": 0.174624, "p": 0.501454, "placebo_affected": 51, "placebo_at_risk": 67544, "rr": 1.1908, "se": 0.259778, "se_clustered": 0.259778, "se_greenland_robins": 0.189439, "strata_with_events": 23, "trials": 234, "trials_with_events": 23 }, "discovered": false, "discovery": { "clustered_wider": true, "glp1_affected": 42, "glp1_at_risk": 47388, "hi": 2.36737, "lo": 0.669862, "log_rr": 0.230548, "p": 0.474085, "placebo_affected": 31, "placebo_at_risk": 35018, "rr": 1.25929, "se": 0.322063, "se_clustered": 0.322063, "se_greenland_robins": 0.24331, "strata_with_events": 14, "trials": 117, "trials_with_events": 14 }, "discovery_q": 0.852233, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 24, "glp1_at_risk": 46377, "hi": 2.63471, "lo": 0.450048, "log_rr": 0.0851866, "p": 0.850124, "placebo_affected": 20, "placebo_at_risk": 32526, "rr": 1.08892, "se": 0.450818, "se_clustered": 0.450818, "se_greenland_robins": 0.30224, "strata_with_events": 9, "trials": 117, "trials_with_events": 9 } }, "Vertigo positional": { "all": { "clustered_wider": true, "glp1_affected": 26, "glp1_at_risk": 93765, "hi": 2.41614, "lo": 0.561459, "log_rr": 0.152477, "p": 0.682133, "placebo_affected": 20, "placebo_at_risk": 67544, "rr": 1.16472, "se": 0.3723, "se_clustered": 0.3723, "se_greenland_robins": 0.288842, "strata_with_events": 15, "trials": 234, "trials_with_events": 15 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 12, "glp1_at_risk": 47388, "hi": 1.53751, "lo": 0.361261, "log_rr": -0.293995, "p": 0.4262, "placebo_affected": 15, "placebo_at_risk": 35018, "rr": 0.74528, "se": 0.369475, "se_clustered": 0.346093, "se_greenland_robins": 0.369475, "strata_with_events": 7, "trials": 117, "trials_with_events": 7 }, "discovery_q": 0.848188, "replicated": false, "replication": { "clustered_wider": true, "glp1_affected": 14, "glp1_at_risk": 46377, "hi": 9.02881, "lo": 0.654728, "log_rr": 0.888442, "p": 0.184428, "placebo_affected": 5, "placebo_at_risk": 32526, "rr": 2.43134, "se": 0.669389, "se_clustered": 0.669389, "se_greenland_robins": 0.514019, "strata_with_events": 8, "trials": 117, "trials_with_events": 8 } }, "Vestibular neuronitis": { "all": { "clustered_wider": false, "glp1_affected": 15, "glp1_at_risk": 93765, "hi": 2.82569, "lo": 0.573457, "log_rr": 0.24134, "p": 0.553054, "placebo_affected": 11, "placebo_at_risk": 67544, "rr": 1.27295, "se": 0.406851, "se_clustered": 0.322203, "se_greenland_robins": 0.406851, "strata_with_events": 9, "trials": 234, "trials_with_events": 9 }, "discovered": false, "discovery": { "clustered_wider": false, "glp1_affected": 6, "glp1_at_risk": 47388, "hi": 2.16163, "lo": 0.260307, "log_rr": -0.287516, "p": 0.594422, "placebo_affected": 8, 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