{
 "note": "Computed blind to arm (code/analyze.py --blind): participants affected, both arms together, and the power of a two-sided 5% test to detect the VA hazard ratio.",
 "outcomes": {
  "A01": {
   "name": "Alcohol use disorder",
   "participants_affected": 48,
   "testable": true,
   "va_hr": 0.89,
   "power_for_va_hr": 0.06,
   "informative": false,
   "overlap_bound": 2.0,
   "dominant_term": "Alcohol poisoning"
  },
  "A02": {
   "name": "Cannabis use disorder",
   "participants_affected": 0,
   "testable": false,
   "va_hr": 0.88,
   "power_for_va_hr": 0.0,
   "informative": false
  },
  "A03": {
   "name": "Stimulant use disorder",
   "participants_affected": 0,
   "testable": false,
   "va_hr": 0.84,
   "power_for_va_hr": 0.0,
   "informative": false
  },
  "A04": {
   "name": "Opioid use disorder",
   "participants_affected": 0,
   "testable": false,
   "va_hr": 0.87,
   "power_for_va_hr": 0.0,
   "informative": false
  },
  "A05": {
   "name": "Suicidal ideation, suicide attempt, or intentional self-harm",
   "participants_affected": 121,
   "testable": true,
   "va_hr": 0.9,
   "power_for_va_hr": 0.084,
   "informative": false,
   "overlap_bound": 1.7794,
   "dominant_term": "Suicide attempt"
  },
  "A06": {
   "name": "Bulimia",
   "participants_affected": 1,
   "testable": false,
   "va_hr": 0.81,
   "power_for_va_hr": 0.032,
   "informative": false
  },
  "A07": {
   "name": "Schizophrenia and other psychotic disorders",
   "participants_affected": 25,
   "testable": true,
   "va_hr": 0.82,
   "power_for_va_hr": 0.072,
   "informative": false,
   "overlap_bound": 1.6667,
   "dominant_term": "Psychotic disorder"
  },
  "A08": {
   "name": "Seizures",
   "participants_affected": 228,
   "testable": true,
   "va_hr": 0.9,
   "power_for_va_hr": 0.122,
   "informative": false,
   "overlap_bound": 1.916,
   "dominant_term": "Seizure"
  },
  "A09": {
   "name": "Neurocognitive disorders",
   "participants_affected": 129,
   "testable": true,
   "va_hr": 0.95,
   "power_for_va_hr": 0.048,
   "informative": false,
   "overlap_bound": 2.0572,
   "dominant_term": "Dementia"
  },
  "A10": {
   "name": "Dementia",
   "participants_affected": 91,
   "testable": true,
   "va_hr": 0.92,
   "power_for_va_hr": 0.059,
   "informative": false,
   "overlap_bound": 2.0572,
   "dominant_term": "Dementia"
  },
  "A11": {
   "name": "Coagulopathy and clotting disorders",
   "participants_affected": 55,
   "testable": true,
   "va_hr": 0.92,
   "power_for_va_hr": 0.049,
   "informative": false,
   "overlap_bound": 1.8333,
   "dominant_term": "International normalised ratio increased"
  },
  "A12": {
   "name": "Venous thromboembolism",
   "participants_affected": 565,
   "testable": true,
   "va_hr": 0.86,
   "power_for_va_hr": 0.433,
   "informative": false,
   "overlap_bound": 1.7601,
   "dominant_term": "Pulmonary embolism"
  },
  "A13": {
   "name": "Pulmonary embolism",
   "participants_affected": 314,
   "testable": true,
   "va_hr": 0.88,
   "power_for_va_hr": 0.204,
   "informative": false,
   "overlap_bound": 1.0295,
   "dominant_term": "Pulmonary embolism"
  },
  "A14": {
   "name": "Deep vein thrombosis",
   "participants_affected": 184,
   "testable": true,
   "va_hr": 0.92,
   "power_for_va_hr": 0.082,
   "informative": false,
   "overlap_bound": 1.0952,
   "dominant_term": "Deep vein thrombosis"
  },
  "A15": {
   "name": "Phlebitis",
   "participants_affected": 28,
   "testable": true,
   "va_hr": 0.86,
   "power_for_va_hr": 0.059,
   "informative": false,
   "overlap_bound": 1.4737,
   "dominant_term": "Thrombophlebitis"
  },
  "A16": {
   "name": "Pulmonary hypertension",
   "participants_affected": 47,
   "testable": true,
   "va_hr": 0.82,
   "power_for_va_hr": 0.1,
   "informative": false,
   "overlap_bound": 1.2368,
   "dominant_term": "Pulmonary hypertension"
  },
  "A17": {
   "name": "Acute kidney injury",
   "participants_affected": 1773,
   "testable": true,
   "va_hr": 0.88,
   "power_for_va_hr": 0.768,
   "informative": false,
   "overlap_bound": 1.2913,
   "dominant_term": "Acute kidney injury"
  },
  "A18": {
   "name": "Bacterial infections",
   "participants_affected": 4941,
   "testable": true,
   "va_hr": 0.88,
   "power_for_va_hr": 0.994,
   "informative": true,
   "overlap_bound": 2.0572,
   "dominant_term": "Urinary tract infection"
  },
  "A19": {
   "name": "Bacterial pneumonia",
   "participants_affected": 181,
   "testable": true,
   "va_hr": 0.89,
   "power_for_va_hr": 0.12,
   "informative": false,
   "overlap_bound": 1.6455,
   "dominant_term": "Pneumonia bacterial"
  },
  "A20": {
   "name": "Sepsis",
   "participants_affected": 1202,
   "testable": true,
   "va_hr": 0.83,
   "power_for_va_hr": 0.898,
   "informative": true,
   "overlap_bound": 2.0572,
   "dominant_term": "Sepsis"
  },
  "A21": {
   "name": "Pneumonia",
   "participants_affected": 3010,
   "testable": true,
   "va_hr": 0.84,
   "power_for_va_hr": 0.998,
   "informative": true,
   "overlap_bound": 1.6323,
   "dominant_term": "Pneumonia"
  },
  "A22": {
   "name": "Aspiration",
   "participants_affected": 100,
   "testable": true,
   "va_hr": 0.75,
   "power_for_va_hr": 0.301,
   "informative": false,
   "overlap_bound": 1.1364,
   "dominant_term": "Pneumonia aspiration"
  },
  "A23": {
   "name": "Pneumonitis",
   "participants_affected": 120,
   "testable": true,
   "va_hr": 0.89,
   "power_for_va_hr": 0.093,
   "informative": false,
   "overlap_bound": 1.3333,
   "dominant_term": "Pneumonia aspiration"
  },
  "A24": {
   "name": "Postprocedural respiratory complications",
   "participants_affected": 33,
   "testable": true,
   "va_hr": 0.82,
   "power_for_va_hr": 0.082,
   "informative": false,
   "overlap_bound": 1.5,
   "dominant_term": "Postoperative thoracic procedure complication"
  },
  "A25": {
   "name": "Pleural effusion",
   "participants_affected": 210,
   "testable": true,
   "va_hr": 0.86,
   "power_for_va_hr": 0.193,
   "informative": false,
   "overlap_bound": 1.2426,
   "dominant_term": "Pleural effusion"
  },
  "A26": {
   "name": "Chronic obstructive pulmonary disease",
   "participants_affected": 605,
   "testable": true,
   "va_hr": 0.9,
   "power_for_va_hr": 0.253,
   "informative": false,
   "overlap_bound": 1.1245,
   "dominant_term": "Chronic obstructive pulmonary disease"
  },
  "A27": {
   "name": "Respiratory failure",
   "participants_affected": 724,
   "testable": true,
   "va_hr": 0.77,
   "power_for_va_hr": 0.94,
   "informative": true,
   "overlap_bound": 1.7876,
   "dominant_term": "Acute respiratory failure"
  },
  "A28": {
   "name": "Anaemia",
   "participants_affected": 718,
   "testable": true,
   "va_hr": 0.97,
   "power_for_va_hr": 0.06,
   "informative": false,
   "overlap_bound": 1.7014,
   "dominant_term": "Anaemia"
  },
  "A29": {
   "name": "Muscle pain",
   "participants_affected": 35,
   "testable": true,
   "va_hr": 0.92,
   "power_for_va_hr": 0.043,
   "informative": false,
   "overlap_bound": 1.4,
   "dominant_term": "Polymyalgia rheumatica"
  },
  "A30": {
   "name": "Hepatic failure",
   "participants_affected": 61,
   "testable": true,
   "va_hr": 0.76,
   "power_for_va_hr": 0.187,
   "informative": false,
   "overlap_bound": 1.7429,
   "dominant_term": "Hepatic encephalopathy"
  },
  "A31": {
   "name": "Inflammatory bowel disease",
   "participants_affected": 32,
   "testable": true,
   "va_hr": 0.88,
   "power_for_va_hr": 0.055,
   "informative": false,
   "overlap_bound": 1.4546,
   "dominant_term": "Colitis ulcerative"
  },
  "A32": {
   "name": "Liver cancer",
   "participants_affected": 143,
   "testable": true,
   "va_hr": 0.82,
   "power_for_va_hr": 0.22,
   "informative": false,
   "overlap_bound": 1.43,
   "dominant_term": "Hepatocellular carcinoma"
  },
  "A33": {
   "name": "Abdominal pain",
   "participants_affected": 305,
   "testable": true,
   "va_hr": 1.12,
   "power_for_va_hr": 0.166,
   "informative": false,
   "overlap_bound": 1.5561,
   "dominant_term": "Abdominal pain"
  },
  "A34": {
   "name": "Nausea and vomiting",
   "participants_affected": 283,
   "testable": true,
   "va_hr": 1.3,
   "power_for_va_hr": 0.597,
   "informative": false,
   "overlap_bound": 1.5215,
   "dominant_term": "Vomiting"
  },
  "A35": {
   "name": "Gastro-oesophageal reflux disease",
   "participants_affected": 183,
   "testable": true,
   "va_hr": 1.14,
   "power_for_va_hr": 0.141,
   "informative": false,
   "overlap_bound": 1.4297,
   "dominant_term": "Gastrooesophageal reflux disease"
  },
  "A36": {
   "name": "Gastritis",
   "participants_affected": 338,
   "testable": true,
   "va_hr": 1.1,
   "power_for_va_hr": 0.139,
   "informative": false,
   "overlap_bound": 1.7884,
   "dominant_term": "Gastritis"
  },
  "A37": {
   "name": "Noninfectious gastroenteritis or colitis",
   "participants_affected": 184,
   "testable": true,
   "va_hr": 1.12,
   "power_for_va_hr": 0.117,
   "informative": false,
   "overlap_bound": 1.7037,
   "dominant_term": "Colitis"
  },
  "A38": {
   "name": "Gastroparesis",
   "participants_affected": 37,
   "testable": true,
   "va_hr": 1.07,
   "power_for_va_hr": 0.04,
   "informative": false,
   "overlap_bound": 1.2333,
   "dominant_term": "Impaired gastric emptying"
  },
  "A39": {
   "name": "Diverticular disease",
   "participants_affected": 287,
   "testable": true,
   "va_hr": 1.08,
   "power_for_va_hr": 0.095,
   "informative": false,
   "overlap_bound": 1.6215,
   "dominant_term": "Diverticulitis"
  },
  "A40": {
   "name": "Hypotension",
   "participants_affected": 330,
   "testable": true,
   "va_hr": 1.06,
   "power_for_va_hr": 0.076,
   "informative": false,
   "overlap_bound": 1.4798,
   "dominant_term": "Hypotension"
  },
  "A41": {
   "name": "Syncope",
   "participants_affected": 615,
   "testable": true,
   "va_hr": 1.06,
   "power_for_va_hr": 0.108,
   "informative": false,
   "overlap_bound": 1.2526,
   "dominant_term": "Syncope"
  },
  "A42": {
   "name": "Sleep disturbances",
   "participants_affected": 88,
   "testable": true,
   "va_hr": 1.12,
   "power_for_va_hr": 0.077,
   "informative": false,
   "overlap_bound": 1.1892,
   "dominant_term": "Sleep apnoea syndrome"
  },
  "A43": {
   "name": "Headache",
   "participants_affected": 133,
   "testable": true,
   "va_hr": 1.1,
   "power_for_va_hr": 0.079,
   "informative": false,
   "overlap_bound": 1.622,
   "dominant_term": "Headache"
  },
  "A44": {
   "name": "Arthritis",
   "participants_affected": 1407,
   "testable": true,
   "va_hr": 1.11,
   "power_for_va_hr": 0.499,
   "informative": false,
   "overlap_bound": 1.3727,
   "dominant_term": "Osteoarthritis"
  },
  "A45": {
   "name": "Arthralgia",
   "participants_affected": 148,
   "testable": true,
   "va_hr": 1.11,
   "power_for_va_hr": 0.093,
   "informative": false,
   "overlap_bound": 1.1654,
   "dominant_term": "Arthralgia"
  },
  "A46": {
   "name": "Tendinitis and synovitis",
   "participants_affected": 267,
   "testable": true,
   "va_hr": 1.1,
   "power_for_va_hr": 0.119,
   "informative": false,
   "overlap_bound": 2.0572,
   "dominant_term": "Rotator cuff syndrome"
  },
  "A47": {
   "name": "Interstitial nephritis",
   "participants_affected": 9,
   "testable": false,
   "va_hr": 1.06,
   "power_for_va_hr": 0.031,
   "informative": false
  },
  "A48": {
   "name": "Kidney stones",
   "participants_affected": 600,
   "testable": true,
   "va_hr": 1.15,
   "power_for_va_hr": 0.402,
   "informative": false,
   "overlap_bound": 1.7647,
   "dominant_term": "Nephrolithiasis"
  },
  "A49": {
   "name": "Acute pancreatitis",
   "participants_affected": 402,
   "testable": true,
   "va_hr": 2.46,
   "power_for_va_hr": 1.0,
   "informative": true,
   "overlap_bound": 1.4725,
   "dominant_term": "Pancreatitis acute"
  },
  "B01": {
   "name": "Gallbladder and biliary disease",
   "participants_affected": 1556,
   "testable": true,
   "overlap_bound": 2.0572,
   "dominant_term": "Cholelithiasis"
  },
  "B02": {
   "name": "Intestinal obstruction or ileus",
   "participants_affected": 324,
   "testable": true,
   "overlap_bound": 2.0572,
   "dominant_term": "Small intestinal obstruction"
  },
  "B03": {
   "name": "Ischaemic optic neuropathy",
   "participants_affected": 15,
   "testable": true,
   "overlap_bound": 1.0714,
   "dominant_term": "Optic ischaemic neuropathy"
  },
  "B04": {
   "name": "Diabetic retinopathy complications",
   "participants_affected": 231,
   "testable": true,
   "overlap_bound": 1.7111,
   "dominant_term": "Diabetic retinopathy"
  },
  "B05": {
   "name": "Thyroid cancer",
   "participants_affected": 99,
   "testable": true,
   "overlap_bound": 1.2073,
   "dominant_term": "Papillary thyroid cancer"
  },
  "B06": {
   "name": "Any malignant neoplasm",
   "participants_affected": 4520,
   "testable": true,
   "overlap_bound": 2.0572,
   "dominant_term": "Prostate cancer"
  },
  "B07": {
   "name": "Obesity-associated cancers",
   "participants_affected": 1781,
   "testable": true,
   "overlap_bound": 2.0572,
   "dominant_term": "Adenocarcinoma of colon"
  },
  "B08": {
   "name": "Depression",
   "participants_affected": 173,
   "testable": true,
   "overlap_bound": 1.3106,
   "dominant_term": "Depression"
  },
  "B09": {
   "name": "Fractures",
   "participants_affected": 1706,
   "testable": true,
   "overlap_bound": 2.0572,
   "dominant_term": "Femur fracture"
  },
  "B10": {
   "name": "Falls",
   "participants_affected": 729,
   "testable": true,
   "overlap_bound": 1.0,
   "dominant_term": "Fall"
  },
  "B11": {
   "name": "Pancreatic cancer",
   "participants_affected": 198,
   "testable": true,
   "overlap_bound": 1.7217,
   "dominant_term": "Pancreatic carcinoma"
  },
  "B12": {
   "name": "Death from any cause",
   "participants_affected": 5404,
   "testable": true,
   "overlap_bound": 1.0
  },
  "B13": {
   "name": "Any serious adverse event",
   "participants_affected": 35031,
   "testable": true,
   "overlap_bound": 1.0
  }
 },
 "family_c_organ_systems": 27,
 "family_d_preferred_terms": 518,
 "overcount_factor": 2.05718
}