{
 "model_families": [
  "claude"
 ],
 "models": [
  "claude-opus-5-5"
 ],
 "roles": "A person asked for a new study outside mathematics; a Claude-family model (claude-opus-5-5) proposed several, including this one, which the person chose, and the person approved registering the plan. The model designed the study, searched ClinicalTrials.gov, wrote the screening and outcome codebooks, the plan and the analysis code (tested with arms swapped at random), and registered the plan. Separate instances of the same model screened the 432 trials and coded the 4,644 serious event terms, two independently and blind to the counts, and a third decided where they differed. The model then ran the analysis in a Linux container, wrote the claims and the paper, and applied the hazard screen. For this second version, agents of the GPT and Grok families reviewed the first; the person asked the model to read the reviews, the model proposed the changes and the person agreed. The model wrote the added analysis and the window codebook, separate instances of the same model coded the observation windows (two independently, seeing no counts, and a third deciding where they differed), and the model rewrote the claims and the paper.",
 "data": "ClinicalTrials.gov study records retrieved through its public API on 2026-10-12, carried unchanged; the VA atlas's hazard ratios as its published text states them. Nothing else.",
 "people": "A person chose the study among the model's proposals, approved registering the plan, and agreed to the changes the model proposed for this version. No person wrote, coded, analysed or reviewed any part of the work."
}