{
 "age": {
  "G1": {
   "age_max": "60.8",
   "age_min": "9.3",
   "comparisons": "51",
   "name": "Serious suicidal behaviour by trial mean age, all acute trials",
   "p": "0.38",
   "pct_hi": "5.1",
   "pct_lo": "−1.9",
   "pct_per_year": "1.5"
  },
  "G2": {
   "age_max": "60.8",
   "age_min": "9.3",
   "comparisons": "73",
   "name": "Any serious suicidality by trial mean age, all acute trials",
   "p": "0.28",
   "pct_hi": "1.1",
   "pct_lo": "−3.5",
   "pct_per_year": "−1.3"
  }
 },
 "checks": {
  "K1": {
   "affected": "8,157",
   "all": {
    "comparisons": "207",
    "comparisons_with_events": "204",
    "drug_affected": "6,100",
    "drug_at_risk": "33,497",
    "hi": "2.18",
    "lo": "1.98",
    "p": "< 0.001",
    "participants": "57,580",
    "placebo_affected": "2,057",
    "placebo_at_risk": "24,083",
    "rr": "2.08"
   },
   "as_expected": true,
   "name": "Nausea, adult acute trials (positive control)",
   "p": "< 0.001"
  },
  "K2": {
   "affected": "295",
   "all": {
    "comparisons": "121",
    "comparisons_with_events": "15",
    "drug_affected": "159",
    "drug_at_risk": "11,053",
    "hi": "1.39",
    "lo": "0.98",
    "p": "0.076",
    "participants": "20,743",
    "placebo_affected": "136",
    "placebo_at_risk": "9,690",
    "rr": "1.17"
   },
   "as_expected": null,
   "name": "Death from any cause, adult acute trials",
   "p": "0.076"
  },
  "K3": {
   "affected": "1,656",
   "all": {
    "comparisons": "322",
    "comparisons_with_events": "193",
    "drug_affected": "913",
    "drug_at_risk": "40,564",
    "hi": "1.19",
    "lo": "0.997",
    "p": "0.057",
    "participants": "71,643",
    "placebo_affected": "743",
    "placebo_at_risk": "31,079",
    "rr": "1.09"
   },
   "as_expected": null,
   "name": "Any serious adverse event, adult acute trials",
   "p": "0.057"
  }
 },
 "completed_after_year": "2017",
 "corrected": {
  "against": {
   "A19": {
    "hammad_2006_pediatric_suicidality": "every"
   },
   "P1": {
    "hengartner_2019_attempts": "every",
    "kaminski_2020_attempts": "every",
    "stone_2009_behaviour_25_64": "some",
    "stone_2009_behaviour_25_and_over": "none"
   },
   "P1_neither": {
    "hengartner_2019_attempts": "every",
    "kaminski_2020_attempts": "every",
    "stone_2009_behaviour_25_64": "some",
    "stone_2009_behaviour_25_and_over": "none"
   },
   "P2": {
    "kaminski_2020_attempts": "every",
    "stone_2009_suicidality_25_64": "none"
   },
   "P2_neither": {
    "kaminski_2020_attempts": "every",
    "stone_2009_suicidality_25_64": "some"
   }
  },
  "age": {
   "G1": {
    "comparisons_with_events": "51",
    "configurations": "192",
    "median_age_comparisons": "0",
    "p_max": "0.65",
    "p_min": "0.21",
    "pct_max": "2.3",
    "pct_min": "0.8"
   },
   "G2": {
    "comparisons_with_events": "73",
    "configurations": "589,824",
    "median_age_comparisons": "0",
    "p_max": "0.61",
    "p_min": "0.12",
    "pct_max": "−0.6",
    "pct_min": "−1.8"
   }
  },
  "bounds": {
   "A10": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "9",
    "drug_at_risk": "7,550",
    "drug_least": "9",
    "drug_most": "9",
    "hi_max": "7.05",
    "hi_min": "7.05",
    "highest": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "lo_max": "0.66",
    "lo_min": "0.66",
    "lowest": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "name": "Serious suicidal behaviour, adult acute trials completed after 2017",
    "p": "0.20",
    "p_max": "0.20",
    "p_min": "0.20",
    "placebo": "4",
    "placebo_at_risk": "6,733",
    "placebo_least": "4",
    "placebo_most": "4",
    "q": "0.28",
    "q_at_p_max": "0.28",
    "q_at_p_min": "0.28",
    "rr": "2.16",
    "rr_max": "2.16",
    "rr_min": "2.16",
    "separate": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "shared": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "significant": "0",
    "testable": true
   },
   "A11": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "10",
    "drug_at_risk": "8,120",
    "drug_least": "10",
    "drug_most": "10",
    "hi_max": "11.62",
    "hi_min": "11.62",
    "highest": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "lo_max": "0.79",
    "lo_min": "0.79",
    "lowest": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "name": "Serious suicidal behaviour, adult acute trials of SSRIs",
    "p": "0.11",
    "p_max": "0.11",
    "p_min": "0.11",
    "placebo": "3",
    "placebo_at_risk": "7,533",
    "placebo_least": "3",
    "placebo_most": "3",
    "q": "0.19 to 0.21",
    "q_at_p_max": "0.21",
    "q_at_p_min": "0.19",
    "rr": "3.03",
    "rr_max": "3.03",
    "rr_min": "3.03",
    "separate": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "shared": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "significant": "0",
    "testable": true
   },
   "A12": {
    "ambiguous_arms": "1",
    "configurations": "2",
    "drug": "12 to 13",
    "drug_at_risk": "11,734",
    "drug_least": "12",
    "drug_most": "13",
    "hi_max": "7.84",
    "hi_min": "7.25",
    "highest": {
     "drug_affected": "13",
     "hi": "7.84",
     "lo": "0.81",
     "p": "0.11",
     "placebo_affected": "4",
     "rr": "2.52"
    },
    "lo_max": "0.81",
    "lo_min": "0.72",
    "lowest": {
     "drug_affected": "12",
     "hi": "7.25",
     "lo": "0.72",
     "p": "0.16",
     "placebo_affected": "4",
     "rr": "2.29"
    },
    "name": "Serious suicidal behaviour, adult acute trials of SNRIs",
    "p": "0.11 to 0.16",
    "p_max": "0.16",
    "p_min": "0.11",
    "placebo": "4",
    "placebo_at_risk": "8,940",
    "placebo_least": "4",
    "placebo_most": "4",
    "q": "0.19 to 0.27",
    "q_at_p_max": "0.27",
    "q_at_p_min": "0.19",
    "rr": "2.29 to 2.52",
    "rr_max": "2.52",
    "rr_min": "2.29",
    "separate": {
     "drug_affected": "13",
     "hi": "7.84",
     "lo": "0.81",
     "p": "0.11",
     "placebo_affected": "4",
     "rr": "2.52"
    },
    "shared": {
     "drug_affected": "12",
     "hi": "7.25",
     "lo": "0.72",
     "p": "0.16",
     "placebo_affected": "4",
     "rr": "2.29"
    },
    "significant": "0",
    "testable": true
   },
   "A13": {
    "ambiguous_arms": "1",
    "configurations": "3",
    "drug": "2",
    "drug_at_risk": "5,609",
    "drug_least": "2",
    "drug_most": "2",
    "hi_max": "7.22",
    "hi_min": "2.76",
    "highest": {
     "drug_affected": "2",
     "hi": "7.22",
     "lo": "0.14",
     "p": "0.99",
     "placebo_affected": "2",
     "rr": "1.01"
    },
    "lo_max": "0.14",
    "lo_min": "0.09",
    "lowest": {
     "drug_affected": "2",
     "hi": "2.76",
     "lo": "0.09",
     "p": "0.43",
     "placebo_affected": "4",
     "rr": "0.50"
    },
    "name": "Serious suicidal behaviour, adult acute trials of bupropion",
    "p": "0.43 to 0.99",
    "p_max": "0.99",
    "p_min": "0.43",
    "placebo": "2 to 4",
    "placebo_at_risk": "5,348",
    "placebo_least": "2",
    "placebo_most": "4",
    "rr": "0.50 to 1.01",
    "rr_max": "1.01",
    "rr_min": "0.50",
    "separate": {
     "drug_affected": "2",
     "hi": "2.76",
     "lo": "0.09",
     "p": "0.43",
     "placebo_affected": "4",
     "rr": "0.50"
    },
    "shared": {
     "drug_affected": "2",
     "hi": "7.22",
     "lo": "0.14",
     "p": "0.99",
     "placebo_affected": "2",
     "rr": "1.01"
    },
    "significant": "0",
    "testable": false
   },
   "A14": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "9",
    "drug_at_risk": "2,999",
    "drug_least": "9",
    "drug_most": "9",
    "hi_max": "6.93",
    "hi_min": "6.93",
    "highest": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "lo_max": "0.63",
    "lo_min": "0.63",
    "lowest": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "name": "Serious suicidal behaviour, adult acute trials of novel-mechanism antidepressants",
    "p": "0.23",
    "p_max": "0.23",
    "p_min": "0.23",
    "placebo": "4",
    "placebo_at_risk": "2,592",
    "placebo_least": "4",
    "placebo_most": "4",
    "q": "0.28",
    "q_at_p_max": "0.28",
    "q_at_p_min": "0.28",
    "rr": "2.09",
    "rr_max": "2.09",
    "rr_min": "2.09",
    "separate": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "shared": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "significant": "0",
    "testable": true
   },
   "A15": {
    "ambiguous_arms": "1",
    "configurations": "2",
    "drug": "4",
    "drug_at_risk": "6,256",
    "drug_least": "4",
    "drug_most": "4",
    "hi_max": "3.63",
    "hi_min": "2.60",
    "highest": {
     "drug_affected": "4",
     "hi": "3.63",
     "lo": "0.13",
     "p": "0.65",
     "placebo_affected": "3",
     "rr": "0.68"
    },
    "lo_max": "0.13",
    "lo_min": "0.11",
    "lowest": {
     "drug_affected": "4",
     "hi": "2.60",
     "lo": "0.11",
     "p": "0.43",
     "placebo_affected": "4",
     "rr": "0.53"
    },
    "name": "Serious suicidal behaviour, adult acute trials of tricyclic, MAOI and other monoaminergic antidepressants",
    "p": "0.43 to 0.65",
    "p_max": "0.65",
    "p_min": "0.43",
    "placebo": "3 to 4",
    "placebo_at_risk": "4,465",
    "placebo_least": "3",
    "placebo_most": "4",
    "rr": "0.53 to 0.68",
    "rr_max": "0.68",
    "rr_min": "0.53",
    "separate": {
     "drug_affected": "4",
     "hi": "2.60",
     "lo": "0.11",
     "p": "0.43",
     "placebo_affected": "4",
     "rr": "0.53"
    },
    "shared": {
     "drug_affected": "4",
     "hi": "3.63",
     "lo": "0.13",
     "p": "0.65",
     "placebo_affected": "3",
     "rr": "0.68"
    },
    "significant": "0",
    "testable": false
   },
   "A16": {
    "ambiguous_arms": "5",
    "configurations": "48",
    "drug": "43 to 46",
    "drug_at_risk": "48,900",
    "drug_least": "43",
    "drug_most": "46",
    "hi_max": "3.99",
    "hi_min": "3.11",
    "highest": {
     "drug_affected": "46",
     "hi": "3.99",
     "lo": "1.21",
     "p": "0.0097",
     "placebo_affected": "16",
     "rr": "2.20"
    },
    "lo_max": "1.21",
    "lo_min": "0.9996",
    "lowest": {
     "drug_affected": "43",
     "hi": "3.11",
     "lo": "0.9996",
     "p": "0.0502",
     "placebo_affected": "19",
     "rr": "1.76"
    },
    "name": "Serious suicidal behaviour, adult acute trials, with combination products included",
    "p": "0.0097 to 0.0502",
    "p_max": "0.0502",
    "p_min": "0.0097",
    "placebo": "16 to 19",
    "placebo_at_risk": "37,706",
    "placebo_least": "16",
    "placebo_most": "19",
    "q": "0.044 to 0.13",
    "q_at_p_max": "0.13",
    "q_at_p_min": "0.044",
    "rr": "1.76 to 2.20",
    "rr_max": "2.20",
    "rr_min": "1.76",
    "separate": {
     "drug_affected": "46",
     "hi": "3.27",
     "lo": "1.06",
     "p": "0.030",
     "placebo_affected": "19",
     "rr": "1.86"
    },
    "shared": {
     "drug_affected": "43",
     "hi": "3.78",
     "lo": "1.14",
     "p": "0.017",
     "placebo_affected": "16",
     "rr": "2.08"
    },
    "significant": "47",
    "testable": true
   },
   "A17": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "1",
    "drug_at_risk": "1,935",
    "drug_least": "1",
    "drug_most": "1",
    "highest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "lowest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "name": "Serious suicidal behaviour, adult randomized-withdrawal trials",
    "placebo": "0",
    "placebo_at_risk": "1,490",
    "placebo_least": "0",
    "placebo_most": "0",
    "separate": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "shared": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "significant": "0",
    "testable": false
   },
   "A18": {
    "ambiguous_arms": "2",
    "configurations": "4",
    "drug": "13 to 14",
    "drug_at_risk": "4,547",
    "drug_least": "13",
    "drug_most": "14",
    "hi_max": "4.48",
    "hi_min": "3.00",
    "highest": {
     "drug_affected": "14",
     "hi": "4.48",
     "lo": "0.49",
     "p": "0.49",
     "placebo_affected": "4",
     "rr": "1.48"
    },
    "lo_max": "0.49",
    "lo_min": "0.39",
    "lowest": {
     "drug_affected": "13",
     "hi": "3.00",
     "lo": "0.39",
     "p": "0.89",
     "placebo_affected": "5",
     "rr": "1.08"
    },
    "name": "Serious suicidal behaviour, pediatric acute trials",
    "p": "0.49 to 0.89",
    "p_max": "0.89",
    "p_min": "0.49",
    "placebo": "4 to 5",
    "placebo_at_risk": "2,547",
    "placebo_least": "4",
    "placebo_most": "5",
    "q": "0.49 to 0.89",
    "q_at_p_max": "0.89",
    "q_at_p_min": "0.49",
    "rr": "1.08 to 1.48",
    "rr_max": "1.48",
    "rr_min": "1.08",
    "separate": {
     "drug_affected": "14",
     "hi": "3.22",
     "lo": "0.43",
     "p": "0.76",
     "placebo_affected": "5",
     "rr": "1.17"
    },
    "shared": {
     "drug_affected": "13",
     "hi": "4.18",
     "lo": "0.44",
     "p": "0.59",
     "placebo_affected": "4",
     "rr": "1.36"
    },
    "significant": "0",
    "testable": true
   },
   "A19": {
    "ambiguous_arms": "4",
    "configurations": "16",
    "drug": "34 to 37",
    "drug_at_risk": "4,547",
    "drug_least": "34",
    "drug_most": "37",
    "hi_max": "6.11",
    "hi_min": "4.64",
    "highest": {
     "drug_affected": "37",
     "hi": "6.11",
     "lo": "1.19",
     "p": "0.018",
     "placebo_affected": "7",
     "rr": "2.70"
    },
    "lo_max": "1.19",
    "lo_min": "0.998",
    "lowest": {
     "drug_affected": "34",
     "hi": "4.64",
     "lo": "0.998",
     "p": "0.051",
     "placebo_affected": "8",
     "rr": "2.15"
    },
    "name": "Any serious suicidality, pediatric acute trials",
    "p": "0.018 to 0.051",
    "p_max": "0.051",
    "p_min": "0.018",
    "placebo": "7 to 8",
    "placebo_at_risk": "2,547",
    "placebo_least": "7",
    "placebo_most": "8",
    "q": "0.044 to 0.13",
    "q_at_p_max": "0.13",
    "q_at_p_min": "0.044",
    "rr": "2.15 to 2.70",
    "rr_max": "2.70",
    "rr_min": "2.15",
    "separate": {
     "drug_affected": "37",
     "hi": "4.98",
     "lo": "1.08",
     "p": "0.032",
     "placebo_affected": "8",
     "rr": "2.31"
    },
    "shared": {
     "drug_affected": "34",
     "hi": "5.70",
     "lo": "1.10",
     "p": "0.028",
     "placebo_affected": "7",
     "rr": "2.51"
    },
    "significant": "15",
    "testable": true
   },
   "A2": {
    "ambiguous_arms": "1",
    "configurations": "2",
    "drug": "36",
    "drug_at_risk": "40,564",
    "drug_least": "36",
    "drug_most": "36",
    "hi_max": "2.11",
    "hi_min": "2.01",
    "highest": {
     "drug_affected": "36",
     "hi": "2.11",
     "lo": "0.72",
     "p": "0.45",
     "placebo_affected": "23",
     "rr": "1.23"
    },
    "lo_max": "0.72",
    "lo_min": "0.69",
    "lowest": {
     "drug_affected": "36",
     "hi": "2.01",
     "lo": "0.69",
     "p": "0.54",
     "placebo_affected": "24",
     "rr": "1.18"
    },
    "name": "Serious suicidal ideation, adult acute trials",
    "p": "0.45 to 0.54",
    "p_max": "0.54",
    "p_min": "0.45",
    "placebo": "23 to 24",
    "placebo_at_risk": "31,079",
    "placebo_least": "23",
    "placebo_most": "24",
    "q": "0.49 to 0.60",
    "q_at_p_max": "0.60",
    "q_at_p_min": "0.49",
    "rr": "1.18 to 1.23",
    "rr_max": "1.23",
    "rr_min": "1.18",
    "separate": {
     "drug_affected": "36",
     "hi": "2.01",
     "lo": "0.69",
     "p": "0.54",
     "placebo_affected": "24",
     "rr": "1.18"
    },
    "shared": {
     "drug_affected": "36",
     "hi": "2.11",
     "lo": "0.72",
     "p": "0.45",
     "placebo_affected": "23",
     "rr": "1.23"
    },
    "significant": "0",
    "testable": true
   },
   "A20": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "1",
    "drug_at_risk": "816",
    "drug_least": "1",
    "drug_most": "1",
    "highest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "lowest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "name": "Serious suicidal behaviour, acute trials spanning adolescents and adults",
    "placebo": "0",
    "placebo_at_risk": "796",
    "placebo_least": "0",
    "placebo_most": "0",
    "separate": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "shared": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "significant": "0",
    "testable": false
   },
   "A4": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "5",
    "drug_at_risk": "40,564",
    "drug_least": "5",
    "drug_most": "5",
    "hi_max": "9.41",
    "hi_min": "9.41",
    "highest": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "lo_max": "0.40",
    "lo_min": "0.40",
    "lowest": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "name": "Completed suicide, adult acute trials",
    "p": "0.41",
    "p_max": "0.41",
    "p_min": "0.41",
    "placebo": "2",
    "placebo_at_risk": "31,079",
    "placebo_least": "2",
    "placebo_most": "2",
    "rr": "1.94",
    "rr_max": "1.94",
    "rr_min": "1.94",
    "separate": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "shared": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "significant": "0",
    "testable": false
   },
   "A5": {
    "ambiguous_arms": "6",
    "configurations": "96",
    "drug": "46 to 50",
    "drug_at_risk": "40,564",
    "drug_least": "46",
    "drug_most": "50",
    "hi_max": "3.91",
    "hi_min": "3.04",
    "highest": {
     "drug_affected": "50",
     "hi": "3.91",
     "lo": "1.27",
     "p": "0.0054",
     "placebo_affected": "17",
     "rr": "2.23"
    },
    "lo_max": "1.27",
    "lo_min": "1.03",
    "lowest": {
     "drug_affected": "46",
     "hi": "3.04",
     "lo": "1.03",
     "p": "0.038",
     "placebo_affected": "20",
     "rr": "1.77"
    },
    "name": "Serious suicidal behaviour or overdose of unstated intent, adult acute trials",
    "p": "0.0054 to 0.038",
    "p_max": "0.038",
    "p_min": "0.0054",
    "placebo": "17 to 20",
    "placebo_at_risk": "31,079",
    "placebo_least": "17",
    "placebo_most": "20",
    "q": "0.044 to 0.13",
    "q_at_p_max": "0.13",
    "q_at_p_min": "0.044",
    "rr": "1.77 to 2.23",
    "rr_max": "2.23",
    "rr_min": "1.77",
    "separate": {
     "drug_affected": "50",
     "hi": "3.27",
     "lo": "1.12",
     "p": "0.017",
     "placebo_affected": "20",
     "rr": "1.91"
    },
    "shared": {
     "drug_affected": "46",
     "hi": "3.64",
     "lo": "1.17",
     "p": "0.013",
     "placebo_affected": "17",
     "rr": "2.06"
    },
    "significant": "96",
    "testable": true
   },
   "A6": {
    "ambiguous_arms": "4",
    "configurations": "16",
    "drug": "34 to 37",
    "drug_at_risk": "21,105",
    "drug_least": "34",
    "drug_most": "37",
    "hi_max": "4.83",
    "hi_min": "4.07",
    "highest": {
     "drug_affected": "37",
     "hi": "4.83",
     "lo": "1.17",
     "p": "0.017",
     "placebo_affected": "11",
     "rr": "2.37"
    },
    "lo_max": "1.17",
    "lo_min": "1.01",
    "lowest": {
     "drug_affected": "34",
     "hi": "4.07",
     "lo": "1.01",
     "p": "0.046",
     "placebo_affected": "12",
     "rr": "2.03"
    },
    "name": "Serious suicidal behaviour, adult acute trials of depressive disorders",
    "p": "0.017 to 0.046",
    "p_max": "0.046",
    "p_min": "0.017",
    "placebo": "11 to 12",
    "placebo_at_risk": "13,240",
    "placebo_least": "11",
    "placebo_most": "12",
    "q": "0.044 to 0.13",
    "q_at_p_max": "0.13",
    "q_at_p_min": "0.044",
    "rr": "2.03 to 2.37",
    "rr_max": "2.37",
    "rr_min": "2.03",
    "separate": {
     "drug_affected": "37",
     "hi": "4.36",
     "lo": "1.10",
     "p": "0.026",
     "placebo_affected": "12",
     "rr": "2.19"
    },
    "shared": {
     "drug_affected": "34",
     "hi": "4.51",
     "lo": "1.08",
     "p": "0.031",
     "placebo_affected": "11",
     "rr": "2.20"
    },
    "significant": "16",
    "testable": true
   },
   "A7": {
    "ambiguous_arms": "1",
    "configurations": "3",
    "drug": "4",
    "drug_at_risk": "9,365",
    "drug_least": "4",
    "drug_most": "4",
    "hi_max": "5.90",
    "hi_min": "2.96",
    "highest": {
     "drug_affected": "4",
     "hi": "5.90",
     "lo": "0.29",
     "p": "0.72",
     "placebo_affected": "3",
     "rr": "1.31"
    },
    "lo_max": "0.29",
    "lo_min": "0.21",
    "lowest": {
     "drug_affected": "4",
     "hi": "2.96",
     "lo": "0.21",
     "p": "0.73",
     "placebo_affected": "5",
     "rr": "0.79"
    },
    "name": "Serious suicidal behaviour, adult acute trials of other psychiatric disorders",
    "p": "0.72 to 0.99",
    "p_max": "0.99",
    "p_min": "0.72",
    "placebo": "3 to 5",
    "placebo_at_risk": "8,378",
    "placebo_least": "3",
    "placebo_most": "5",
    "rr": "0.79 to 1.31",
    "rr_max": "1.31",
    "rr_min": "0.79",
    "separate": {
     "drug_affected": "4",
     "hi": "2.96",
     "lo": "0.21",
     "p": "0.73",
     "placebo_affected": "5",
     "rr": "0.79"
    },
    "shared": {
     "drug_affected": "4",
     "hi": "5.90",
     "lo": "0.29",
     "p": "0.72",
     "placebo_affected": "3",
     "rr": "1.31"
    },
    "significant": "0",
    "testable": false
   },
   "A8": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "5",
    "drug_at_risk": "10,094",
    "drug_least": "5",
    "drug_most": "5",
    "hi_max": "12.71",
    "hi_min": "12.71",
    "highest": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "lo_max": "0.48",
    "lo_min": "0.48",
    "lowest": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "name": "Serious suicidal behaviour, adult acute trials of non-psychiatric conditions",
    "p": "0.28",
    "p_max": "0.28",
    "p_min": "0.28",
    "placebo": "2",
    "placebo_at_risk": "9,461",
    "placebo_least": "2",
    "placebo_most": "2",
    "rr": "2.48",
    "rr_max": "2.48",
    "rr_min": "2.48",
    "separate": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "shared": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "significant": "0",
    "testable": false
   },
   "A9": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "0",
    "drug_at_risk": "1,616",
    "drug_least": "0",
    "drug_most": "0",
    "highest": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "lowest": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "name": "Serious suicidal behaviour, acute trials enrolling only people aged 60 or over",
    "placebo": "0",
    "placebo_at_risk": "1,121",
    "placebo_least": "0",
    "placebo_most": "0",
    "separate": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "shared": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "significant": "0",
    "testable": false
   },
   "P1": {
    "ambiguous_arms": "5",
    "configurations": "48",
    "drug": "43 to 46",
    "drug_at_risk": "40,564",
    "drug_least": "43",
    "drug_most": "46",
    "hi_max": "3.99",
    "hi_min": "3.11",
    "highest": {
     "drug_affected": "46",
     "hi": "3.99",
     "lo": "1.21",
     "p": "0.0097",
     "placebo_affected": "16",
     "rr": "2.20"
    },
    "holm_at_p_max": "0.10",
    "holm_at_p_min": "0.016",
    "holm_separate": "0.060",
    "holm_shared": "0.034",
    "lo_max": "1.21",
    "lo_min": "0.9996",
    "lowest": {
     "drug_affected": "43",
     "hi": "3.11",
     "lo": "0.9996",
     "p": "0.0502",
     "placebo_affected": "19",
     "rr": "1.76"
    },
    "name": "Serious suicidal behaviour, adult trials randomized from the start",
    "p": "0.0097 to 0.0502",
    "p_max": "0.0502",
    "p_min": "0.0097",
    "placebo": "16 to 19",
    "placebo_at_risk": "31,079",
    "placebo_least": "16",
    "placebo_most": "19",
    "rr": "1.76 to 2.20",
    "rr_max": "2.20",
    "rr_min": "1.76",
    "separate": {
     "drug_affected": "46",
     "hi": "3.27",
     "lo": "1.06",
     "p": "0.030",
     "placebo_affected": "19",
     "rr": "1.86"
    },
    "shared": {
     "drug_affected": "43",
     "hi": "3.78",
     "lo": "1.14",
     "p": "0.017",
     "placebo_affected": "16",
     "rr": "2.08"
    },
    "significant": "47",
    "testable": true
   },
   "P2": {
    "ambiguous_arms": "13",
    "configurations": "36,864",
    "drug": "71 to 81",
    "drug_at_risk": "40,564",
    "drug_least": "71",
    "drug_most": "81",
    "hi_max": "2.60",
    "hi_min": "1.92",
    "highest": {
     "drug_affected": "81",
     "hi": "2.60",
     "lo": "1.16",
     "p": "0.0078",
     "placebo_affected": "36",
     "rr": "1.73"
    },
    "holm_at_p_max": "0.20",
    "holm_at_p_min": "0.016",
    "holm_separate": "0.060",
    "holm_shared": "0.044",
    "lo_max": "1.16",
    "lo_min": "0.87",
    "lowest": {
     "drug_affected": "71",
     "hi": "1.92",
     "lo": "0.87",
     "p": "0.20",
     "placebo_affected": "43",
     "rr": "1.29"
    },
    "name": "Any serious suicidality (behaviour or ideation), adult trials randomized from the start",
    "p": "0.0078 to 0.20",
    "p_max": "0.20",
    "p_min": "0.0078",
    "placebo": "36 to 43",
    "placebo_at_risk": "31,079",
    "placebo_least": "36",
    "placebo_most": "43",
    "rr": "1.29 to 1.73",
    "rr_max": "1.73",
    "rr_min": "1.29",
    "separate": {
     "drug_affected": "81",
     "hi": "2.15",
     "lo": "0.998",
     "p": "0.051",
     "placebo_affected": "43",
     "rr": "1.47"
    },
    "shared": {
     "drug_affected": "71",
     "hi": "2.32",
     "lo": "1.01",
     "p": "0.044",
     "placebo_affected": "36",
     "rr": "1.53"
    },
    "significant": "19,746",
    "testable": true
   }
  },
  "checks": {
   "K1": {
    "ambiguous_arms": "1",
    "configurations": "3",
    "drug": "6,098 to 6,100",
    "drug_at_risk": "33,497",
    "drug_least": "6,098",
    "drug_most": "6,100",
    "hi_max": "2.18",
    "hi_min": "2.18",
    "highest": {
     "drug_affected": "6,100",
     "hi": "2.18",
     "lo": "1.98",
     "p": "< 0.001",
     "placebo_affected": "2,057",
     "rr": "2.08"
    },
    "lo_max": "1.98",
    "lo_min": "1.98",
    "lowest": {
     "drug_affected": "6,098",
     "hi": "2.18",
     "lo": "1.98",
     "p": "< 0.001",
     "placebo_affected": "2,057",
     "rr": "2.08"
    },
    "name": "K1",
    "p": "< 0.001",
    "p_max": "< 0.001",
    "p_min": "< 0.001",
    "placebo": "2,057",
    "placebo_at_risk": "24,083",
    "placebo_least": "2,057",
    "placebo_most": "2,057",
    "rr": "2.08",
    "rr_max": "2.08",
    "rr_min": "2.08",
    "separate": {
     "drug_affected": "6,100",
     "hi": "2.18",
     "lo": "1.98",
     "p": "< 0.001",
     "placebo_affected": "2,057",
     "rr": "2.08"
    },
    "shared": {
     "drug_affected": "6,098",
     "hi": "2.18",
     "lo": "1.98",
     "p": "< 0.001",
     "placebo_affected": "2,057",
     "rr": "2.08"
    },
    "significant": "3",
    "testable": true
   }
  },
  "estimators": {
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    "comparisons_with_events": "14",
    "dl": {
     "hi": "3.33",
     "i2": "0.00",
     "lo": "0.84",
     "p": "0.14",
     "rr": "1.67",
     "tau2": "0.00"
    },
    "highest_common": {
     "hi": "6.66",
     "lo": "1.27",
     "p": "0.0086",
     "rr": "2.70",
     "tau": "0.00"
    },
    "highest_random": {
     "hi": "7.15",
     "lo": "1.27",
     "p": "0.0087",
     "rr": "2.70",
     "tau": "0.00"
    },
    "inverse_variance_corrected": {
     "hi": "3.33",
     "lo": "0.84",
     "p": "0.14",
     "rr": "1.67"
    },
    "lowest_common": {
     "hi": "5.10",
     "lo": "1.05",
     "p": "0.036",
     "rr": "2.18",
     "tau": "0.00"
    },
    "lowest_random": {
     "hi": "5.89",
     "lo": "1.05",
     "p": "0.036",
     "rr": "2.18",
     "tau": "0.00"
    },
    "registered_common": {
     "hi": "5.70",
     "lo": "1.19",
     "p": "0.014",
     "rr": "2.44",
     "tau": "0.00"
    },
    "registered_random": {
     "hi": "6.62",
     "lo": "1.19",
     "p": "0.014",
     "rr": "2.44",
     "tau": "0.00"
    },
    "with_a_zero_cell": "8"
   },
   "A6": {
    "comparisons_with_events": "34",
    "dl": {
     "hi": "2.08",
     "i2": "0.00",
     "lo": "0.75",
     "p": "0.40",
     "rr": "1.24",
     "tau2": "0.00"
    },
    "highest_common": {
     "hi": "4.79",
     "lo": "1.20",
     "p": "0.011",
     "rr": "2.30",
     "tau": "0.00"
    },
    "highest_random": {
     "hi": "7.87",
     "lo": "1.20",
     "p": "0.011",
     "rr": "2.30",
     "tau": "0.00"
    },
    "inverse_variance_corrected": {
     "hi": "2.08",
     "lo": "0.75",
     "p": "0.40",
     "rr": "1.24"
    },
    "lowest_common": {
     "hi": "4.02",
     "lo": "1.04",
     "p": "0.037",
     "rr": "1.98",
     "tau": "0.00"
    },
    "lowest_random": {
     "hi": "7.86",
     "lo": "1.04",
     "p": "0.037",
     "rr": "1.98",
     "tau": "0.00"
    },
    "registered_common": {
     "hi": "4.29",
     "lo": "1.13",
     "p": "0.019",
     "rr": "2.12",
     "tau": "0.00"
    },
    "registered_random": {
     "hi": "10.73",
     "lo": "1.13",
     "p": "0.019",
     "rr": "2.12",
     "tau": "0.00"
    },
    "with_a_zero_cell": "30"
   },
   "P1": {
    "comparisons_with_events": "43",
    "dl": {
     "hi": "1.90",
     "i2": "0.00",
     "lo": "0.78",
     "p": "0.38",
     "rr": "1.22",
     "tau2": "0.00"
    },
    "highest_common": {
     "hi": "3.94",
     "lo": "1.23",
     "p": "0.0065",
     "rr": "2.15",
     "tau": "0.00"
    },
    "highest_random": {
     "hi": "4.53",
     "lo": "1.23",
     "p": "0.0065",
     "rr": "2.15",
     "tau": "0.00"
    },
    "inverse_variance_corrected": {
     "hi": "1.90",
     "lo": "0.78",
     "p": "0.38",
     "rr": "1.22"
    },
    "lowest_common": {
     "hi": "3.06",
     "lo": "1.01",
     "p": "0.044",
     "rr": "1.73",
     "tau": "0.00"
    },
    "lowest_random": {
     "hi": "3.84",
     "lo": "1.01",
     "p": "0.044",
     "rr": "1.73",
     "tau": "0.00"
    },
    "registered_common": {
     "hi": "3.21",
     "lo": "1.08",
     "p": "0.025",
     "rr": "1.82",
     "tau": "0.00"
    },
    "registered_random": {
     "hi": "4.41",
     "lo": "1.08",
     "p": "0.025",
     "rr": "1.82",
     "tau": "0.00"
    },
    "with_a_zero_cell": "37"
   },
   "P2": {
    "comparisons_with_events": "61",
    "dl": {
     "hi": "1.55",
     "i2": "0.00",
     "lo": "0.78",
     "p": "0.59",
     "rr": "1.10",
     "tau2": "0.00"
    },
    "highest_common": {
     "hi": "2.59",
     "lo": "1.16",
     "p": "0.0064",
     "rr": "1.72",
     "tau": "0.00"
    },
    "highest_random": {
     "hi": "2.62",
     "lo": "1.16",
     "p": "0.0064",
     "rr": "1.72",
     "tau": "0.00"
    },
    "inverse_variance_corrected": {
     "hi": "1.55",
     "lo": "0.78",
     "p": "0.59",
     "rr": "1.10"
    },
    "lowest_common": {
     "hi": "1.90",
     "lo": "0.88",
     "p": "0.20",
     "rr": "1.29",
     "tau": "0.00"
    },
    "lowest_random": {
     "hi": "2.27",
     "lo": "0.88",
     "p": "0.20",
     "rr": "1.31",
     "tau": "0.23"
    },
    "registered_common": {
     "hi": "2.15",
     "lo": "1.01",
     "p": "0.043",
     "rr": "1.47",
     "tau": "0.00"
    },
    "registered_random": {
     "hi": "2.58",
     "lo": "1.01",
     "p": "0.041",
     "rr": "1.50",
     "tau": "0.26"
    },
    "with_a_zero_cell": "46"
   }
  },
  "independence": {
   "P1": {
    "in_reanalyses": {
     "ambiguous_arms": "2",
     "comparisons": "16",
     "configurations": "4",
     "drug": "7 to 9",
     "drug_at_risk": "5,668",
     "drug_least": "7",
     "drug_most": "9",
     "hi_max": "61.72",
     "hi_min": "49.42",
     "highest": {
      "drug_affected": "9",
      "hi": "61.72",
      "lo": "0.52",
      "p": "0.16",
      "placebo_affected": "1",
      "rr": "5.65"
     },
     "lo_max": "0.52",
     "lo_min": "0.34",
     "lowest": {
      "drug_affected": "7",
      "hi": "49.42",
      "lo": "0.34",
      "p": "0.26",
      "placebo_affected": "1",
      "rr": "4.12"
     },
     "name": "in_reanalyses",
     "p": "0.16 to 0.26",
     "p_max": "0.26",
     "p_min": "0.16",
     "participants": "8,487",
     "placebo": "1",
     "placebo_at_risk": "2,819",
     "placebo_least": "1",
     "placebo_most": "1",
     "resolved": {
      "ambiguous_arms": "0",
      "configurations": "1",
      "drug": "7",
      "drug_at_risk": "5,668",
      "drug_least": "7",
      "drug_most": "7",
      "hi_max": "49.42",
      "hi_min": "49.42",
      "highest": {
       "drug_affected": "7",
       "hi": "49.42",
       "lo": "0.34",
       "p": "0.26",
       "placebo_affected": "1",
       "rr": "4.12"
      },
      "lo_max": "0.34",
      "lo_min": "0.34",
      "lowest": {
       "drug_affected": "7",
       "hi": "49.42",
       "lo": "0.34",
       "p": "0.26",
       "placebo_affected": "1",
       "rr": "4.12"
      },
      "name": "in_reanalyses",
      "p": "0.26",
      "p_max": "0.26",
      "p_min": "0.26",
      "placebo": "1",
      "placebo_at_risk": "2,819",
      "placebo_least": "1",
      "placebo_most": "1",
      "rr": "4.12",
      "rr_max": "4.12",
      "rr_min": "4.12",
      "separate": {
       "drug_affected": "7",
       "hi": "49.42",
       "lo": "0.34",
       "p": "0.26",
       "placebo_affected": "1",
       "rr": "4.12"
      },
      "shared": {
       "drug_affected": "7",
       "hi": "49.42",
       "lo": "0.34",
       "p": "0.26",
       "placebo_affected": "1",
       "rr": "4.12"
      },
      "significant": "0",
      "testable": false
     },
     "rr": "4.12 to 5.65",
     "rr_max": "5.65",
     "rr_min": "4.12",
     "separate": {
      "drug_affected": "9",
      "hi": "61.72",
      "lo": "0.52",
      "p": "0.16",
      "placebo_affected": "1",
      "rr": "5.65"
     },
     "shared": {
      "drug_affected": "7",
      "hi": "49.42",
      "lo": "0.34",
      "p": "0.26",
      "placebo_affected": "1",
      "rr": "4.12"
     },
     "significant": "0",
     "testable": false,
     "trials": "16"
    },
    "neither": {
     "ambiguous_arms": "3",
     "comparisons": "304",
     "configurations": "12",
     "drug": "36 to 37",
     "drug_at_risk": "34,647",
     "drug_least": "36",
     "drug_most": "37",
     "hi_max": "3.67",
     "hi_min": "2.93",
     "highest": {
      "drug_affected": "37",
      "hi": "3.67",
      "lo": "1.07",
      "p": "0.030",
      "placebo_affected": "15",
      "rr": "1.98"
     },
     "lo_max": "1.07",
     "lo_min": "0.91",
     "lowest": {
      "drug_affected": "36",
      "hi": "2.93",
      "lo": "0.91",
      "p": "0.097",
      "placebo_affected": "18",
      "rr": "1.64"
     },
     "name": "neither",
     "p": "0.030 to 0.097",
     "p_max": "0.097",
     "p_min": "0.030",
     "participants": "62,652",
     "placebo": "15 to 18",
     "placebo_at_risk": "28,005",
     "placebo_least": "15",
     "placebo_most": "18",
     "resolved": {
      "ambiguous_arms": "1",
      "configurations": "2",
      "drug": "36",
      "drug_at_risk": "34,647",
      "drug_least": "36",
      "drug_most": "36",
      "hi_max": "3.36",
      "hi_min": "3.13",
      "highest": {
       "drug_affected": "36",
       "hi": "3.36",
       "lo": "1.001",
       "p": "0.0497",
       "placebo_affected": "16",
       "rr": "1.83"
      },
      "lo_max": "1.001",
      "lo_min": "0.96",
      "lowest": {
       "drug_affected": "36",
       "hi": "3.13",
       "lo": "0.96",
       "p": "0.070",
       "placebo_affected": "17",
       "rr": "1.73"
      },
      "name": "neither",
      "p": "0.0497 to 0.070",
      "p_max": "0.070",
      "p_min": "0.0497",
      "placebo": "16 to 17",
      "placebo_at_risk": "28,005",
      "placebo_least": "16",
      "placebo_most": "17",
      "rr": "1.73 to 1.83",
      "rr_max": "1.83",
      "rr_min": "1.73",
      "separate": {
       "drug_affected": "36",
       "hi": "3.13",
       "lo": "0.96",
       "p": "0.070",
       "placebo_affected": "17",
       "rr": "1.73"
      },
      "shared": {
       "drug_affected": "36",
       "hi": "3.36",
       "lo": "1.001",
       "p": "0.0497",
       "placebo_affected": "16",
       "rr": "1.83"
      },
      "significant": "1",
      "testable": true
     },
     "rr": "1.64 to 1.98",
     "rr_max": "1.98",
     "rr_min": "1.64",
     "separate": {
      "drug_affected": "37",
      "hi": "2.98",
      "lo": "0.93",
      "p": "0.087",
      "placebo_affected": "18",
      "rr": "1.66"
     },
     "shared": {
      "drug_affected": "36",
      "hi": "3.61",
      "lo": "1.05",
      "p": "0.034",
      "placebo_affected": "15",
      "rr": "1.95"
     },
     "significant": "6",
     "testable": true,
     "trials": "288"
    },
    "possibly_fda_2006": {
     "ambiguous_arms": "0",
     "comparisons": "2",
     "configurations": "1",
     "drug": "0",
     "drug_at_risk": "249",
     "drug_least": "0",
     "drug_most": "0",
     "highest": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "lowest": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "name": "possibly_fda_2006",
     "participants": "504",
     "placebo": "0",
     "placebo_at_risk": "255",
     "placebo_least": "0",
     "placebo_most": "0",
     "resolved": {
      "ambiguous_arms": "0",
      "configurations": "1",
      "drug": "0",
      "drug_at_risk": "249",
      "drug_least": "0",
      "drug_most": "0",
      "highest": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "lowest": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "name": "possibly_fda_2006",
      "placebo": "0",
      "placebo_at_risk": "255",
      "placebo_least": "0",
      "placebo_most": "0",
      "separate": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "shared": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "significant": "0",
      "testable": false
     },
     "separate": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "shared": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "significant": "0",
     "testable": false,
     "trials": "2"
    }
   },
   "P2": {
    "in_reanalyses": {
     "ambiguous_arms": "2",
     "comparisons": "16",
     "configurations": "6",
     "drug": "11 to 14",
     "drug_at_risk": "5,668",
     "drug_least": "11",
     "drug_most": "14",
     "hi_max": "92.33",
     "hi_min": "72.95",
     "highest": {
      "drug_affected": "14",
      "hi": "92.33",
      "lo": "0.93",
      "p": "0.058",
      "placebo_affected": "1",
      "rr": "9.26"
     },
     "lo_max": "0.93",
     "lo_min": "0.62",
     "lowest": {
      "drug_affected": "11",
      "hi": "72.95",
      "lo": "0.62",
      "p": "0.12",
      "placebo_affected": "1",
      "rr": "6.73"
     },
     "name": "in_reanalyses",
     "p": "0.058 to 0.12",
     "p_max": "0.12",
     "p_min": "0.058",
     "participants": "8,487",
     "placebo": "1",
     "placebo_at_risk": "2,819",
     "placebo_least": "1",
     "placebo_most": "1",
     "resolved": {
      "ambiguous_arms": "1",
      "configurations": "2",
      "drug": "11 to 12",
      "drug_at_risk": "5,668",
      "drug_least": "11",
      "drug_most": "12",
      "hi_max": "79.75",
      "hi_min": "72.95",
      "highest": {
       "drug_affected": "12",
       "hi": "79.75",
       "lo": "0.75",
       "p": "0.086",
       "placebo_affected": "1",
       "rr": "7.74"
      },
      "lo_max": "0.75",
      "lo_min": "0.62",
      "lowest": {
       "drug_affected": "11",
       "hi": "72.95",
       "lo": "0.62",
       "p": "0.12",
       "placebo_affected": "1",
       "rr": "6.73"
      },
      "name": "in_reanalyses",
      "p": "0.086 to 0.12",
      "p_max": "0.12",
      "p_min": "0.086",
      "placebo": "1",
      "placebo_at_risk": "2,819",
      "placebo_least": "1",
      "placebo_most": "1",
      "rr": "6.73 to 7.74",
      "rr_max": "7.74",
      "rr_min": "6.73",
      "separate": {
       "drug_affected": "12",
       "hi": "79.75",
       "lo": "0.75",
       "p": "0.086",
       "placebo_affected": "1",
       "rr": "7.74"
      },
      "shared": {
       "drug_affected": "11",
       "hi": "72.95",
       "lo": "0.62",
       "p": "0.12",
       "placebo_affected": "1",
       "rr": "6.73"
      },
      "significant": "0",
      "testable": true
     },
     "rr": "6.73 to 9.26",
     "rr_max": "9.26",
     "rr_min": "6.73",
     "separate": {
      "drug_affected": "14",
      "hi": "92.33",
      "lo": "0.93",
      "p": "0.058",
      "placebo_affected": "1",
      "rr": "9.26"
     },
     "shared": {
      "drug_affected": "11",
      "hi": "72.95",
      "lo": "0.62",
      "p": "0.12",
      "placebo_affected": "1",
      "rr": "6.73"
     },
     "significant": "0",
     "testable": true,
     "trials": "16"
    },
    "neither": {
     "ambiguous_arms": "11",
     "comparisons": "304",
     "configurations": "6,144",
     "drug": "60 to 67",
     "drug_at_risk": "34,647",
     "drug_least": "60",
     "drug_most": "67",
     "hi_max": "2.33",
     "hi_min": "1.75",
     "highest": {
      "drug_affected": "67",
      "hi": "2.33",
      "lo": "1.01",
      "p": "0.044",
      "placebo_affected": "35",
      "rr": "1.53"
     },
     "lo_max": "1.01",
     "lo_min": "0.78",
     "lowest": {
      "drug_affected": "60",
      "hi": "1.75",
      "lo": "0.78",
      "p": "0.44",
      "placebo_affected": "42",
      "rr": "1.17"
     },
     "name": "neither",
     "p": "0.044 to 0.44",
     "p_max": "0.44",
     "p_min": "0.044",
     "participants": "62,652",
     "placebo": "35 to 42",
     "placebo_at_risk": "28,005",
     "placebo_least": "35",
     "placebo_most": "42",
     "resolved": {
      "ambiguous_arms": "5",
      "configurations": "32",
      "drug": "61 to 65",
      "drug_at_risk": "34,647",
      "drug_least": "61",
      "drug_most": "65",
      "hi_max": "2.04",
      "hi_min": "1.88",
      "highest": {
       "drug_affected": "65",
       "hi": "2.04",
       "lo": "0.91",
       "p": "0.14",
       "placebo_affected": "39",
       "rr": "1.36"
      },
      "lo_max": "0.91",
      "lo_min": "0.83",
      "lowest": {
       "drug_affected": "61",
       "hi": "1.88",
       "lo": "0.83",
       "p": "0.28",
       "placebo_affected": "40",
       "rr": "1.25"
      },
      "name": "neither",
      "p": "0.14 to 0.28",
      "p_max": "0.28",
      "p_min": "0.14",
      "placebo": "39 to 40",
      "placebo_at_risk": "28,005",
      "placebo_least": "39",
      "placebo_most": "40",
      "rr": "1.25 to 1.36",
      "rr_max": "1.36",
      "rr_min": "1.25",
      "separate": {
       "drug_affected": "65",
       "hi": "1.98",
       "lo": "0.89",
       "p": "0.17",
       "placebo_affected": "40",
       "rr": "1.33"
      },
      "shared": {
       "drug_affected": "61",
       "hi": "1.93",
       "lo": "0.85",
       "p": "0.24",
       "placebo_affected": "39",
       "rr": "1.28"
      },
      "significant": "0",
      "testable": true
     },
     "rr": "1.17 to 1.53",
     "rr_max": "1.53",
     "rr_min": "1.17",
     "separate": {
      "drug_affected": "67",
      "hi": "1.92",
      "lo": "0.87",
      "p": "0.21",
      "placebo_affected": "42",
      "rr": "1.29"
     },
     "shared": {
      "drug_affected": "60",
      "hi": "2.12",
      "lo": "0.91",
      "p": "0.13",
      "placebo_affected": "35",
      "rr": "1.39"
     },
     "significant": "3",
     "testable": true,
     "trials": "288"
    },
    "possibly_fda_2006": {
     "ambiguous_arms": "0",
     "comparisons": "2",
     "configurations": "1",
     "drug": "0",
     "drug_at_risk": "249",
     "drug_least": "0",
     "drug_most": "0",
     "highest": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "lowest": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "name": "possibly_fda_2006",
     "participants": "504",
     "placebo": "0",
     "placebo_at_risk": "255",
     "placebo_least": "0",
     "placebo_most": "0",
     "resolved": {
      "ambiguous_arms": "0",
      "configurations": "1",
      "drug": "0",
      "drug_at_risk": "249",
      "drug_least": "0",
      "drug_most": "0",
      "highest": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "lowest": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "name": "possibly_fda_2006",
      "placebo": "0",
      "placebo_at_risk": "255",
      "placebo_least": "0",
      "placebo_most": "0",
      "separate": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "shared": {
       "drug_affected": "0",
       "hi": null,
       "lo": null,
       "p": null,
       "placebo_affected": "0",
       "rr": null
      },
      "significant": "0",
      "testable": false
     },
     "separate": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "shared": {
      "drug_affected": "0",
      "hi": null,
      "lo": null,
      "p": null,
      "placebo_affected": "0",
      "rr": null
     },
     "significant": "0",
     "testable": false,
     "trials": "2"
    }
   },
   "pediatric": {
    "comparisons": "30",
    "completed_after_fda_2004": "30",
    "first_completion": "2006"
   }
  },
  "resolution": {
   "groups": "17",
   "groups_narrowed": "3",
   "groups_settled": "11",
   "groups_unresolved": "3",
   "narrowed": "5",
   "outcome_bounds": "31",
   "settled": "23"
  },
  "resolved": {
   "A10": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "9",
    "drug_at_risk": "7,550",
    "drug_least": "9",
    "drug_most": "9",
    "hi_max": "7.05",
    "hi_min": "7.05",
    "highest": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "lo_max": "0.66",
    "lo_min": "0.66",
    "lowest": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "name": "Serious suicidal behaviour, adult acute trials completed after 2017",
    "p": "0.20",
    "p_max": "0.20",
    "p_min": "0.20",
    "placebo": "4",
    "placebo_at_risk": "6,733",
    "placebo_least": "4",
    "placebo_most": "4",
    "q": "0.28",
    "q_at_p_max": "0.28",
    "q_at_p_min": "0.28",
    "rr": "2.16",
    "rr_max": "2.16",
    "rr_min": "2.16",
    "separate": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "shared": {
     "drug_affected": "9",
     "hi": "7.05",
     "lo": "0.66",
     "p": "0.20",
     "placebo_affected": "4",
     "rr": "2.16"
    },
    "significant": "0",
    "testable": true
   },
   "A11": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "10",
    "drug_at_risk": "8,120",
    "drug_least": "10",
    "drug_most": "10",
    "hi_max": "11.62",
    "hi_min": "11.62",
    "highest": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "lo_max": "0.79",
    "lo_min": "0.79",
    "lowest": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "name": "Serious suicidal behaviour, adult acute trials of SSRIs",
    "p": "0.11",
    "p_max": "0.11",
    "p_min": "0.11",
    "placebo": "3",
    "placebo_at_risk": "7,533",
    "placebo_least": "3",
    "placebo_most": "3",
    "q": "0.21",
    "q_at_p_max": "0.21",
    "q_at_p_min": "0.21",
    "rr": "3.03",
    "rr_max": "3.03",
    "rr_min": "3.03",
    "separate": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "shared": {
     "drug_affected": "10",
     "hi": "11.62",
     "lo": "0.79",
     "p": "0.11",
     "placebo_affected": "3",
     "rr": "3.03"
    },
    "significant": "0",
    "testable": true
   },
   "A12": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "12",
    "drug_at_risk": "11,734",
    "drug_least": "12",
    "drug_most": "12",
    "hi_max": "7.25",
    "hi_min": "7.25",
    "highest": {
     "drug_affected": "12",
     "hi": "7.25",
     "lo": "0.72",
     "p": "0.16",
     "placebo_affected": "4",
     "rr": "2.29"
    },
    "lo_max": "0.72",
    "lo_min": "0.72",
    "lowest": {
     "drug_affected": "12",
     "hi": "7.25",
     "lo": "0.72",
     "p": "0.16",
     "placebo_affected": "4",
     "rr": "2.29"
    },
    "name": "Serious suicidal behaviour, adult acute trials of SNRIs",
    "p": "0.16",
    "p_max": "0.16",
    "p_min": "0.16",
    "placebo": "4",
    "placebo_at_risk": "8,940",
    "placebo_least": "4",
    "placebo_most": "4",
    "q": "0.27",
    "q_at_p_max": "0.27",
    "q_at_p_min": "0.27",
    "rr": "2.29",
    "rr_max": "2.29",
    "rr_min": "2.29",
    "separate": {
     "drug_affected": "12",
     "hi": "7.25",
     "lo": "0.72",
     "p": "0.16",
     "placebo_affected": "4",
     "rr": "2.29"
    },
    "shared": {
     "drug_affected": "12",
     "hi": "7.25",
     "lo": "0.72",
     "p": "0.16",
     "placebo_affected": "4",
     "rr": "2.29"
    },
    "significant": "0",
    "testable": true
   },
   "A13": {
    "ambiguous_arms": "1",
    "configurations": "2",
    "drug": "2",
    "drug_at_risk": "5,609",
    "drug_least": "2",
    "drug_most": "2",
    "hi_max": "4.04",
    "hi_min": "2.76",
    "highest": {
     "drug_affected": "2",
     "hi": "4.04",
     "lo": "0.11",
     "p": "0.66",
     "placebo_affected": "3",
     "rr": "0.67"
    },
    "lo_max": "0.11",
    "lo_min": "0.09",
    "lowest": {
     "drug_affected": "2",
     "hi": "2.76",
     "lo": "0.09",
     "p": "0.43",
     "placebo_affected": "4",
     "rr": "0.50"
    },
    "name": "Serious suicidal behaviour, adult acute trials of bupropion",
    "p": "0.43 to 0.66",
    "p_max": "0.66",
    "p_min": "0.43",
    "placebo": "3 to 4",
    "placebo_at_risk": "5,348",
    "placebo_least": "3",
    "placebo_most": "4",
    "rr": "0.50 to 0.67",
    "rr_max": "0.67",
    "rr_min": "0.50",
    "separate": {
     "drug_affected": "2",
     "hi": "2.76",
     "lo": "0.09",
     "p": "0.43",
     "placebo_affected": "4",
     "rr": "0.50"
    },
    "shared": {
     "drug_affected": "2",
     "hi": "4.04",
     "lo": "0.11",
     "p": "0.66",
     "placebo_affected": "3",
     "rr": "0.67"
    },
    "significant": "0",
    "testable": false
   },
   "A14": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "9",
    "drug_at_risk": "2,999",
    "drug_least": "9",
    "drug_most": "9",
    "hi_max": "6.93",
    "hi_min": "6.93",
    "highest": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "lo_max": "0.63",
    "lo_min": "0.63",
    "lowest": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "name": "Serious suicidal behaviour, adult acute trials of novel-mechanism antidepressants",
    "p": "0.23",
    "p_max": "0.23",
    "p_min": "0.23",
    "placebo": "4",
    "placebo_at_risk": "2,592",
    "placebo_least": "4",
    "placebo_most": "4",
    "q": "0.28",
    "q_at_p_max": "0.28",
    "q_at_p_min": "0.28",
    "rr": "2.09",
    "rr_max": "2.09",
    "rr_min": "2.09",
    "separate": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "shared": {
     "drug_affected": "9",
     "hi": "6.93",
     "lo": "0.63",
     "p": "0.23",
     "placebo_affected": "4",
     "rr": "2.09"
    },
    "significant": "0",
    "testable": true
   },
   "A15": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "4",
    "drug_at_risk": "6,256",
    "drug_least": "4",
    "drug_most": "4",
    "hi_max": "3.63",
    "hi_min": "3.63",
    "highest": {
     "drug_affected": "4",
     "hi": "3.63",
     "lo": "0.13",
     "p": "0.65",
     "placebo_affected": "3",
     "rr": "0.68"
    },
    "lo_max": "0.13",
    "lo_min": "0.13",
    "lowest": {
     "drug_affected": "4",
     "hi": "3.63",
     "lo": "0.13",
     "p": "0.65",
     "placebo_affected": "3",
     "rr": "0.68"
    },
    "name": "Serious suicidal behaviour, adult acute trials of tricyclic, MAOI and other monoaminergic antidepressants",
    "p": "0.65",
    "p_max": "0.65",
    "p_min": "0.65",
    "placebo": "3",
    "placebo_at_risk": "4,465",
    "placebo_least": "3",
    "placebo_most": "3",
    "rr": "0.68",
    "rr_max": "0.68",
    "rr_min": "0.68",
    "separate": {
     "drug_affected": "4",
     "hi": "3.63",
     "lo": "0.13",
     "p": "0.65",
     "placebo_affected": "3",
     "rr": "0.68"
    },
    "shared": {
     "drug_affected": "4",
     "hi": "3.63",
     "lo": "0.13",
     "p": "0.65",
     "placebo_affected": "3",
     "rr": "0.68"
    },
    "significant": "0",
    "testable": false
   },
   "A16": {
    "ambiguous_arms": "1",
    "configurations": "2",
    "drug": "43",
    "drug_at_risk": "48,900",
    "drug_least": "43",
    "drug_most": "43",
    "hi_max": "3.53",
    "hi_min": "3.31",
    "highest": {
     "drug_affected": "43",
     "hi": "3.53",
     "lo": "1.09",
     "p": "0.025",
     "placebo_affected": "17",
     "rr": "1.96"
    },
    "lo_max": "1.09",
    "lo_min": "1.04",
    "lowest": {
     "drug_affected": "43",
     "hi": "3.31",
     "lo": "1.04",
     "p": "0.036",
     "placebo_affected": "18",
     "rr": "1.86"
    },
    "name": "Serious suicidal behaviour, adult acute trials, with combination products included",
    "p": "0.025 to 0.036",
    "p_max": "0.036",
    "p_min": "0.025",
    "placebo": "17 to 18",
    "placebo_at_risk": "37,706",
    "placebo_least": "17",
    "placebo_most": "18",
    "q": "0.10 to 0.11",
    "q_at_p_max": "0.11",
    "q_at_p_min": "0.10",
    "rr": "1.86 to 1.96",
    "rr_max": "1.96",
    "rr_min": "1.86",
    "separate": {
     "drug_affected": "43",
     "hi": "3.31",
     "lo": "1.04",
     "p": "0.036",
     "placebo_affected": "18",
     "rr": "1.86"
    },
    "shared": {
     "drug_affected": "43",
     "hi": "3.53",
     "lo": "1.09",
     "p": "0.025",
     "placebo_affected": "17",
     "rr": "1.96"
    },
    "significant": "2",
    "testable": true
   },
   "A17": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "1",
    "drug_at_risk": "1,935",
    "drug_least": "1",
    "drug_most": "1",
    "highest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "lowest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "name": "Serious suicidal behaviour, adult randomized-withdrawal trials",
    "placebo": "0",
    "placebo_at_risk": "1,490",
    "placebo_least": "0",
    "placebo_most": "0",
    "separate": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "shared": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "significant": "0",
    "testable": false
   },
   "A18": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "13",
    "drug_at_risk": "4,547",
    "drug_least": "13",
    "drug_most": "13",
    "hi_max": "3.00",
    "hi_min": "3.00",
    "highest": {
     "drug_affected": "13",
     "hi": "3.00",
     "lo": "0.39",
     "p": "0.89",
     "placebo_affected": "5",
     "rr": "1.08"
    },
    "lo_max": "0.39",
    "lo_min": "0.39",
    "lowest": {
     "drug_affected": "13",
     "hi": "3.00",
     "lo": "0.39",
     "p": "0.89",
     "placebo_affected": "5",
     "rr": "1.08"
    },
    "name": "Serious suicidal behaviour, pediatric acute trials",
    "p": "0.89",
    "p_max": "0.89",
    "p_min": "0.89",
    "placebo": "5",
    "placebo_at_risk": "2,547",
    "placebo_least": "5",
    "placebo_most": "5",
    "q": "0.89",
    "q_at_p_max": "0.89",
    "q_at_p_min": "0.89",
    "rr": "1.08",
    "rr_max": "1.08",
    "rr_min": "1.08",
    "separate": {
     "drug_affected": "13",
     "hi": "3.00",
     "lo": "0.39",
     "p": "0.89",
     "placebo_affected": "5",
     "rr": "1.08"
    },
    "shared": {
     "drug_affected": "13",
     "hi": "3.00",
     "lo": "0.39",
     "p": "0.89",
     "placebo_affected": "5",
     "rr": "1.08"
    },
    "significant": "0",
    "testable": true
   },
   "A19": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "35",
    "drug_at_risk": "4,547",
    "drug_least": "35",
    "drug_most": "35",
    "hi_max": "4.75",
    "hi_min": "4.75",
    "highest": {
     "drug_affected": "35",
     "hi": "4.75",
     "lo": "1.02",
     "p": "0.044",
     "placebo_affected": "8",
     "rr": "2.20"
    },
    "lo_max": "1.02",
    "lo_min": "1.02",
    "lowest": {
     "drug_affected": "35",
     "hi": "4.75",
     "lo": "1.02",
     "p": "0.044",
     "placebo_affected": "8",
     "rr": "2.20"
    },
    "name": "Any serious suicidality, pediatric acute trials",
    "p": "0.044",
    "p_max": "0.044",
    "p_min": "0.044",
    "placebo": "8",
    "placebo_at_risk": "2,547",
    "placebo_least": "8",
    "placebo_most": "8",
    "q": "0.11",
    "q_at_p_max": "0.11",
    "q_at_p_min": "0.11",
    "rr": "2.20",
    "rr_max": "2.20",
    "rr_min": "2.20",
    "separate": {
     "drug_affected": "35",
     "hi": "4.75",
     "lo": "1.02",
     "p": "0.044",
     "placebo_affected": "8",
     "rr": "2.20"
    },
    "shared": {
     "drug_affected": "35",
     "hi": "4.75",
     "lo": "1.02",
     "p": "0.044",
     "placebo_affected": "8",
     "rr": "2.20"
    },
    "significant": "1",
    "testable": true
   },
   "A2": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "36",
    "drug_at_risk": "40,564",
    "drug_least": "36",
    "drug_most": "36",
    "hi_max": "2.01",
    "hi_min": "2.01",
    "highest": {
     "drug_affected": "36",
     "hi": "2.01",
     "lo": "0.69",
     "p": "0.54",
     "placebo_affected": "24",
     "rr": "1.18"
    },
    "lo_max": "0.69",
    "lo_min": "0.69",
    "lowest": {
     "drug_affected": "36",
     "hi": "2.01",
     "lo": "0.69",
     "p": "0.54",
     "placebo_affected": "24",
     "rr": "1.18"
    },
    "name": "Serious suicidal ideation, adult acute trials",
    "p": "0.54",
    "p_max": "0.54",
    "p_min": "0.54",
    "placebo": "24",
    "placebo_at_risk": "31,079",
    "placebo_least": "24",
    "placebo_most": "24",
    "q": "0.60",
    "q_at_p_max": "0.60",
    "q_at_p_min": "0.60",
    "rr": "1.18",
    "rr_max": "1.18",
    "rr_min": "1.18",
    "separate": {
     "drug_affected": "36",
     "hi": "2.01",
     "lo": "0.69",
     "p": "0.54",
     "placebo_affected": "24",
     "rr": "1.18"
    },
    "shared": {
     "drug_affected": "36",
     "hi": "2.01",
     "lo": "0.69",
     "p": "0.54",
     "placebo_affected": "24",
     "rr": "1.18"
    },
    "significant": "0",
    "testable": true
   },
   "A20": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "1",
    "drug_at_risk": "816",
    "drug_least": "1",
    "drug_most": "1",
    "highest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "lowest": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "name": "Serious suicidal behaviour, acute trials spanning adolescents and adults",
    "placebo": "0",
    "placebo_at_risk": "796",
    "placebo_least": "0",
    "placebo_most": "0",
    "separate": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "shared": {
     "drug_affected": "1",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "significant": "0",
    "testable": false
   },
   "A4": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "5",
    "drug_at_risk": "40,564",
    "drug_least": "5",
    "drug_most": "5",
    "hi_max": "9.41",
    "hi_min": "9.41",
    "highest": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "lo_max": "0.40",
    "lo_min": "0.40",
    "lowest": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "name": "Completed suicide, adult acute trials",
    "p": "0.41",
    "p_max": "0.41",
    "p_min": "0.41",
    "placebo": "2",
    "placebo_at_risk": "31,079",
    "placebo_least": "2",
    "placebo_most": "2",
    "rr": "1.94",
    "rr_max": "1.94",
    "rr_min": "1.94",
    "separate": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "shared": {
     "drug_affected": "5",
     "hi": "9.41",
     "lo": "0.40",
     "p": "0.41",
     "placebo_affected": "2",
     "rr": "1.94"
    },
    "significant": "0",
    "testable": false
   },
   "A5": {
    "ambiguous_arms": "1",
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    "drug": "47",
    "drug_at_risk": "40,564",
    "drug_least": "47",
    "drug_most": "47",
    "hi_max": "3.50",
    "hi_min": "3.30",
    "highest": {
     "drug_affected": "47",
     "hi": "3.50",
     "lo": "1.15",
     "p": "0.014",
     "placebo_affected": "18",
     "rr": "2.01"
    },
    "lo_max": "1.15",
    "lo_min": "1.11",
    "lowest": {
     "drug_affected": "47",
     "hi": "3.30",
     "lo": "1.11",
     "p": "0.020",
     "placebo_affected": "19",
     "rr": "1.91"
    },
    "name": "Serious suicidal behaviour or overdose of unstated intent, adult acute trials",
    "p": "0.014 to 0.020",
    "p_max": "0.020",
    "p_min": "0.014",
    "placebo": "18 to 19",
    "placebo_at_risk": "31,079",
    "placebo_least": "18",
    "placebo_most": "19",
    "q": "0.10 to 0.11",
    "q_at_p_max": "0.11",
    "q_at_p_min": "0.10",
    "rr": "1.91 to 2.01",
    "rr_max": "2.01",
    "rr_min": "1.91",
    "separate": {
     "drug_affected": "47",
     "hi": "3.30",
     "lo": "1.11",
     "p": "0.020",
     "placebo_affected": "19",
     "rr": "1.91"
    },
    "shared": {
     "drug_affected": "47",
     "hi": "3.50",
     "lo": "1.15",
     "p": "0.014",
     "placebo_affected": "18",
     "rr": "2.01"
    },
    "significant": "2",
    "testable": true
   },
   "A6": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "34",
    "drug_at_risk": "21,105",
    "drug_least": "34",
    "drug_most": "34",
    "hi_max": "4.51",
    "hi_min": "4.51",
    "highest": {
     "drug_affected": "34",
     "hi": "4.51",
     "lo": "1.08",
     "p": "0.031",
     "placebo_affected": "11",
     "rr": "2.20"
    },
    "lo_max": "1.08",
    "lo_min": "1.08",
    "lowest": {
     "drug_affected": "34",
     "hi": "4.51",
     "lo": "1.08",
     "p": "0.031",
     "placebo_affected": "11",
     "rr": "2.20"
    },
    "name": "Serious suicidal behaviour, adult acute trials of depressive disorders",
    "p": "0.031",
    "p_max": "0.031",
    "p_min": "0.031",
    "placebo": "11",
    "placebo_at_risk": "13,240",
    "placebo_least": "11",
    "placebo_most": "11",
    "q": "0.10 to 0.11",
    "q_at_p_max": "0.11",
    "q_at_p_min": "0.10",
    "rr": "2.20",
    "rr_max": "2.20",
    "rr_min": "2.20",
    "separate": {
     "drug_affected": "34",
     "hi": "4.51",
     "lo": "1.08",
     "p": "0.031",
     "placebo_affected": "11",
     "rr": "2.20"
    },
    "shared": {
     "drug_affected": "34",
     "hi": "4.51",
     "lo": "1.08",
     "p": "0.031",
     "placebo_affected": "11",
     "rr": "2.20"
    },
    "significant": "1",
    "testable": true
   },
   "A7": {
    "ambiguous_arms": "1",
    "configurations": "2",
    "drug": "4",
    "drug_at_risk": "9,365",
    "drug_least": "4",
    "drug_most": "4",
    "hi_max": "3.97",
    "hi_min": "2.96",
    "highest": {
     "drug_affected": "4",
     "hi": "3.97",
     "lo": "0.25",
     "p": "0.99",
     "placebo_affected": "4",
     "rr": "0.99"
    },
    "lo_max": "0.25",
    "lo_min": "0.21",
    "lowest": {
     "drug_affected": "4",
     "hi": "2.96",
     "lo": "0.21",
     "p": "0.73",
     "placebo_affected": "5",
     "rr": "0.79"
    },
    "name": "Serious suicidal behaviour, adult acute trials of other psychiatric disorders",
    "p": "0.73 to 0.99",
    "p_max": "0.99",
    "p_min": "0.73",
    "placebo": "4 to 5",
    "placebo_at_risk": "8,378",
    "placebo_least": "4",
    "placebo_most": "5",
    "rr": "0.79 to 0.99",
    "rr_max": "0.99",
    "rr_min": "0.79",
    "separate": {
     "drug_affected": "4",
     "hi": "2.96",
     "lo": "0.21",
     "p": "0.73",
     "placebo_affected": "5",
     "rr": "0.79"
    },
    "shared": {
     "drug_affected": "4",
     "hi": "3.97",
     "lo": "0.25",
     "p": "0.99",
     "placebo_affected": "4",
     "rr": "0.99"
    },
    "significant": "0",
    "testable": false
   },
   "A8": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "5",
    "drug_at_risk": "10,094",
    "drug_least": "5",
    "drug_most": "5",
    "hi_max": "12.71",
    "hi_min": "12.71",
    "highest": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "lo_max": "0.48",
    "lo_min": "0.48",
    "lowest": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "name": "Serious suicidal behaviour, adult acute trials of non-psychiatric conditions",
    "p": "0.28",
    "p_max": "0.28",
    "p_min": "0.28",
    "placebo": "2",
    "placebo_at_risk": "9,461",
    "placebo_least": "2",
    "placebo_most": "2",
    "rr": "2.48",
    "rr_max": "2.48",
    "rr_min": "2.48",
    "separate": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "shared": {
     "drug_affected": "5",
     "hi": "12.71",
     "lo": "0.48",
     "p": "0.28",
     "placebo_affected": "2",
     "rr": "2.48"
    },
    "significant": "0",
    "testable": false
   },
   "A9": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "0",
    "drug_at_risk": "1,616",
    "drug_least": "0",
    "drug_most": "0",
    "highest": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "lowest": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "name": "Serious suicidal behaviour, acute trials enrolling only people aged 60 or over",
    "placebo": "0",
    "placebo_at_risk": "1,121",
    "placebo_least": "0",
    "placebo_most": "0",
    "separate": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "shared": {
     "drug_affected": "0",
     "hi": null,
     "lo": null,
     "p": null,
     "placebo_affected": "0",
     "rr": null
    },
    "significant": "0",
    "testable": false
   },
   "P1": {
    "ambiguous_arms": "1",
    "configurations": "2",
    "drug": "43",
    "drug_at_risk": "40,564",
    "drug_least": "43",
    "drug_most": "43",
    "hi_max": "3.53",
    "hi_min": "3.31",
    "highest": {
     "drug_affected": "43",
     "hi": "3.53",
     "lo": "1.09",
     "p": "0.025",
     "placebo_affected": "17",
     "rr": "1.96"
    },
    "holm_at_p_max": "0.071",
    "holm_at_p_min": "0.0496",
    "holm_separate": "0.071",
    "holm_shared": "0.0496",
    "lo_max": "1.09",
    "lo_min": "1.04",
    "lowest": {
     "drug_affected": "43",
     "hi": "3.31",
     "lo": "1.04",
     "p": "0.036",
     "placebo_affected": "18",
     "rr": "1.86"
    },
    "name": "Serious suicidal behaviour, adult trials randomized from the start",
    "p": "0.025 to 0.036",
    "p_max": "0.036",
    "p_min": "0.025",
    "placebo": "17 to 18",
    "placebo_at_risk": "31,079",
    "placebo_least": "17",
    "placebo_most": "18",
    "rr": "1.86 to 1.96",
    "rr_max": "1.96",
    "rr_min": "1.86",
    "separate": {
     "drug_affected": "43",
     "hi": "3.31",
     "lo": "1.04",
     "p": "0.036",
     "placebo_affected": "18",
     "rr": "1.86"
    },
    "shared": {
     "drug_affected": "43",
     "hi": "3.53",
     "lo": "1.09",
     "p": "0.025",
     "placebo_affected": "17",
     "rr": "1.96"
    },
    "significant": "2",
    "testable": true
   },
   "P2": {
    "ambiguous_arms": "6",
    "configurations": "64",
    "drug": "72 to 77",
    "drug_at_risk": "40,564",
    "drug_least": "72",
    "drug_most": "77",
    "hi_max": "2.24",
    "hi_min": "2.05",
    "highest": {
     "drug_affected": "77",
     "hi": "2.24",
     "lo": "1.02",
     "p": "0.041",
     "placebo_affected": "40",
     "rr": "1.51"
    },
    "holm_at_p_max": "0.12",
    "holm_at_p_min": "0.0496",
    "holm_separate": "0.071",
    "holm_shared": "0.093",
    "lo_max": "1.02",
    "lo_min": "0.92",
    "lowest": {
     "drug_affected": "72",
     "hi": "2.05",
     "lo": "0.92",
     "p": "0.12",
     "placebo_affected": "41",
     "rr": "1.38"
    },
    "name": "Any serious suicidality (behaviour or ideation), adult trials randomized from the start",
    "p": "0.041 to 0.12",
    "p_max": "0.12",
    "p_min": "0.041",
    "placebo": "40 to 41",
    "placebo_at_risk": "31,079",
    "placebo_least": "40",
    "placebo_most": "41",
    "rr": "1.38 to 1.51",
    "rr_max": "1.51",
    "rr_min": "1.38",
    "separate": {
     "drug_affected": "77",
     "hi": "2.18",
     "lo": "0.997",
     "p": "0.052",
     "placebo_affected": "41",
     "rr": "1.48"
    },
    "shared": {
     "drug_affected": "72",
     "hi": "2.10",
     "lo": "0.94",
     "p": "0.093",
     "placebo_affected": "40",
     "rr": "1.41"
    },
    "significant": "6",
    "testable": true
   }
  },
  "single_term": {
   "P1": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "27",
    "drug_at_risk": "40,564",
    "drug_least": "27",
    "drug_most": "27",
    "hi_max": "3.20",
    "hi_min": "3.20",
    "highest": {
     "drug_affected": "27",
     "hi": "3.20",
     "lo": "0.79",
     "p": "0.19",
     "placebo_affected": "13",
     "rr": "1.59"
    },
    "lo_max": "0.79",
    "lo_min": "0.79",
    "lowest": {
     "drug_affected": "27",
     "hi": "3.20",
     "lo": "0.79",
     "p": "0.19",
     "placebo_affected": "13",
     "rr": "1.59"
    },
    "name": "Suicide attempt",
    "p": "0.19",
    "p_max": "0.19",
    "p_min": "0.19",
    "placebo": "13",
    "placebo_at_risk": "31,079",
    "placebo_least": "13",
    "placebo_most": "13",
    "rr": "1.59",
    "rr_max": "1.59",
    "rr_min": "1.59",
    "separate": {
     "drug_affected": "27",
     "hi": "3.20",
     "lo": "0.79",
     "p": "0.19",
     "placebo_affected": "13",
     "rr": "1.59"
    },
    "shared": {
     "drug_affected": "27",
     "hi": "3.20",
     "lo": "0.79",
     "p": "0.19",
     "placebo_affected": "13",
     "rr": "1.59"
    },
    "significant": "0",
    "term": "suicide attempt",
    "testable": true
   },
   "P2": {
    "ambiguous_arms": "0",
    "configurations": "1",
    "drug": "33",
    "drug_at_risk": "40,564",
    "drug_least": "33",
    "drug_most": "33",
    "hi_max": "2.25",
    "hi_min": "2.25",
    "highest": {
     "drug_affected": "33",
     "hi": "2.25",
     "lo": "0.71",
     "p": "0.42",
     "placebo_affected": "20",
     "rr": "1.27"
    },
    "lo_max": "0.71",
    "lo_min": "0.71",
    "lowest": {
     "drug_affected": "33",
     "hi": "2.25",
     "lo": "0.71",
     "p": "0.42",
     "placebo_affected": "20",
     "rr": "1.27"
    },
    "name": "Suicidal ideation",
    "p": "0.42",
    "p_max": "0.42",
    "p_min": "0.42",
    "placebo": "20",
    "placebo_at_risk": "31,079",
    "placebo_least": "20",
    "placebo_most": "20",
    "rr": "1.27",
    "rr_max": "1.27",
    "rr_min": "1.27",
    "separate": {
     "drug_affected": "33",
     "hi": "2.25",
     "lo": "0.71",
     "p": "0.42",
     "placebo_affected": "20",
     "rr": "1.27"
    },
    "shared": {
     "drug_affected": "33",
     "hi": "2.25",
     "lo": "0.71",
     "p": "0.42",
     "placebo_affected": "20",
     "rr": "1.27"
    },
    "significant": "0",
    "term": "suicidal ideation",
    "testable": true
   }
  }
 },
 "earlier": {
  "hammad_2006_pediatric_suicidality": {
   "hi": "2.98",
   "lo": "1.28",
   "value": "1.95"
  },
  "hengartner_2019_attempts": {
   "hi": "3.61",
   "lo": "1.63",
   "value": "2.38"
  },
  "kaminski_2020_attempts": {
   "hi": "2.43",
   "lo": "1.09",
   "value": "1.63"
  },
  "stone_2009_behaviour_25_64": {
   "hi": "1.58",
   "lo": "0.68",
   "value": "1.03"
  },
  "stone_2009_behaviour_25_and_over": {
   "hi": "1.29",
   "lo": "0.58",
   "value": "0.87"
  },
  "stone_2009_suicidality_25_64": {
   "hi": "0.98",
   "lo": "0.64",
   "value": "0.79"
  }
 },
 "primary": {
  "P1": {
   "affected": "65",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": true,
    "increase": true
   },
   "all": {
    "comparisons": "322",
    "comparisons_with_events": "43",
    "drug_affected": "46",
    "drug_at_risk": "40,564",
    "hi": "3.27",
    "lo": "1.06",
    "p": "0.030",
    "participants": "71,643",
    "placebo_affected": "19",
    "placebo_at_risk": "31,079",
    "rr": "1.86"
   },
   "conservative_p": "0.044",
   "dominant_term": {
    "comparisons": "322",
    "comparisons_with_events": "31",
    "drug_affected": "27",
    "drug_at_risk": "40,564",
    "hi": "3.20",
    "lo": "0.79",
    "p": "0.19",
    "participants": "71,643",
    "placebo_affected": "13",
    "placebo_at_risk": "31,079",
    "rr": "1.59",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "156",
    "comparisons_with_events": "18",
    "drug_affected": "15",
    "drug_at_risk": "19,080",
    "hi": "2.52",
    "lo": "0.48",
    "p": "0.83",
    "participants": "33,544",
    "placebo_affected": "10",
    "placebo_at_risk": "14,464",
    "rr": "1.09"
   },
   "half2": {
    "comparisons": "166",
    "comparisons_with_events": "25",
    "drug_affected": "31",
    "drug_at_risk": "21,484",
    "hi": "6.19",
    "lo": "1.26",
    "p": "0.012",
    "participants": "38,099",
    "placebo_affected": "9",
    "placebo_at_risk": "16,615",
    "rr": "2.79"
   },
   "leave_one_out": {
    "hi_max": "3.79",
    "lo_min": "0.998",
    "p_max": "0.051",
    "p_min": "0.014",
    "rr_max": "2.08",
    "rr_min": "1.76"
   },
   "name": "Serious suicidal behaviour, adult trials randomized from the start",
   "overlap_bound": "1.16",
   "p": "0.030",
   "p_holm": "0.060",
   "per_10000": {
    "drug": "11.3",
    "drug_least": "10.6",
    "drug_most": "11.3",
    "placebo": "6.1",
    "placebo_least": "5.1",
    "placebo_most": "6.1"
   },
   "peto": {
    "hi": "2.91",
    "lo": "1.06",
    "or": "1.76",
    "p": "0.028"
   },
   "power": {
    "hengartner_2019_attempts": "0.93",
    "kaminski_2020_attempts": "0.50",
    "stone_2009_behaviour_25_64": "0.08"
   },
   "random_effects": {
    "hi": "1.90",
    "i2": "0.00",
    "lo": "0.78",
    "p": "0.38",
    "rr": "1.22"
   },
   "robust": false,
   "testable": true
  },
  "P2": {
   "affected": "125",
   "against": {
    "decrease": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_suicidality_25_64": true,
    "increase": true
   },
   "all": {
    "comparisons": "322",
    "comparisons_with_events": "61",
    "drug_affected": "82",
    "drug_at_risk": "40,564",
    "hi": "2.18",
    "lo": "1.01",
    "p": "0.045",
    "participants": "71,643",
    "placebo_affected": "43",
    "placebo_at_risk": "31,079",
    "rr": "1.48"
   },
   "conservative_p": "0.075",
   "dominant_term": {
    "comparisons": "322",
    "comparisons_with_events": "33",
    "drug_affected": "33",
    "drug_at_risk": "40,564",
    "hi": "2.25",
    "lo": "0.71",
    "p": "0.42",
    "participants": "71,643",
    "placebo_affected": "20",
    "placebo_at_risk": "31,079",
    "rr": "1.27",
    "term": "suicidal ideation"
   },
   "half1": {
    "comparisons": "156",
    "comparisons_with_events": "23",
    "drug_affected": "29",
    "drug_at_risk": "19,080",
    "hi": "1.83",
    "lo": "0.56",
    "p": "0.96",
    "participants": "33,544",
    "placebo_affected": "21",
    "placebo_at_risk": "14,464",
    "rr": "1.01"
   },
   "half2": {
    "comparisons": "166",
    "comparisons_with_events": "38",
    "drug_affected": "53",
    "drug_at_risk": "21,484",
    "hi": "3.25",
    "lo": "1.16",
    "p": "0.012",
    "participants": "38,099",
    "placebo_affected": "22",
    "placebo_at_risk": "16,615",
    "rr": "1.94"
   },
   "leave_one_out": {
    "hi_max": "2.45",
    "lo_min": "0.94",
    "p_max": "0.096",
    "p_min": "0.018",
    "rr_max": "1.63",
    "rr_min": "1.39"
   },
   "name": "Any serious suicidality (behaviour or ideation), adult trials randomized from the start",
   "overlap_bound": "1.27",
   "p": "0.045",
   "p_holm": "0.060",
   "per_10000": {
    "drug": "20.2",
    "drug_least": "17.5",
    "drug_most": "20.0",
    "placebo": "13.8",
    "placebo_least": "11.6",
    "placebo_most": "13.8"
   },
   "peto": {
    "hi": "2.09",
    "lo": "1.01",
    "or": "1.45",
    "p": "0.044"
   },
   "power": {
    "kaminski_2020_attempts": "0.77",
    "stone_2009_suicidality_25_64": "0.26"
   },
   "random_effects": {
    "hi": "1.55",
    "i2": "0.00",
    "lo": "0.78",
    "p": "0.59",
    "rr": "1.10"
   },
   "robust": false,
   "testable": true
  }
 },
 "priors": {
  "hammad_2006_pediatric_suicidality": "1.95",
  "hengartner_2019_attempts": "2.38",
  "kaminski_2020_attempts": "1.63",
  "stone_2009_behaviour_25_64": "0.87",
  "stone_2009_behaviour_under_25": "2.30",
  "stone_2009_suicidality_25_64": "0.79",
  "stone_2009_suicidality_under_25": "1.62"
 },
 "secondary": {
  "A10": {
   "affected": "13",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "75",
    "comparisons_with_events": "6",
    "drug_affected": "9",
    "drug_at_risk": "7,550",
    "hi": "7.05",
    "lo": "0.66",
    "p": "0.20",
    "participants": "14,283",
    "placebo_affected": "4",
    "placebo_at_risk": "6,733",
    "rr": "2.16"
   },
   "conservative_p": "0.22",
   "dominant_term": {
    "comparisons": "75",
    "comparisons_with_events": "6",
    "drug_affected": "8",
    "drug_at_risk": "7,550",
    "hi": "6.39",
    "lo": "0.57",
    "p": "0.29",
    "participants": "14,283",
    "placebo_affected": "4",
    "placebo_at_risk": "6,733",
    "rr": "1.91",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "38",
    "comparisons_with_events": "3",
    "drug_affected": "3",
    "drug_at_risk": "3,765",
    "hi": "28.38",
    "lo": "0.32",
    "p": "0.34",
    "participants": "7,497",
    "placebo_affected": "1",
    "placebo_at_risk": "3,732",
    "rr": "3.00"
   },
   "half2": {
    "comparisons": "37",
    "comparisons_with_events": "3",
    "drug_affected": "6",
    "drug_at_risk": "3,785",
    "hi": "7.63",
    "lo": "0.46",
    "p": "0.38",
    "participants": "6,786",
    "placebo_affected": "3",
    "placebo_at_risk": "3,001",
    "rr": "1.88"
   },
   "leave_one_out": {
    "hi_max": "48.56",
    "lo_min": "0.48",
    "p_max": "0.42",
    "p_min": "0.11",
    "rr_max": "5.66",
    "rr_min": "1.66"
   },
   "name": "Serious suicidal behaviour, adult acute trials completed after 2017",
   "overlap_bound": "1.08",
   "p": "0.20",
   "peto": {
    "hi": "6.23",
    "lo": "0.69",
    "or": "2.08",
    "p": "0.19"
   },
   "power": {
    "hengartner_2019_attempts": "0.34",
    "kaminski_2020_attempts": "0.14",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": "0.28",
   "random_effects": {
    "hi": "4.45",
    "i2": "0.00",
    "lo": "0.56",
    "p": "0.38",
    "rr": "1.58"
   },
   "testable": true
  },
  "A11": {
   "affected": "13",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "109",
    "comparisons_with_events": "12",
    "drug_affected": "10",
    "drug_at_risk": "8,120",
    "hi": "11.62",
    "lo": "0.79",
    "p": "0.11",
    "participants": "15,653",
    "placebo_affected": "3",
    "placebo_at_risk": "7,533",
    "rr": "3.03"
   },
   "conservative_p": "0.12",
   "dominant_term": {
    "comparisons": "109",
    "comparisons_with_events": "8",
    "drug_affected": "5",
    "drug_at_risk": "8,120",
    "hi": "6.58",
    "lo": "0.31",
    "p": "0.64",
    "participants": "15,653",
    "placebo_affected": "3",
    "placebo_at_risk": "7,533",
    "rr": "1.43",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "54",
    "comparisons_with_events": "6",
    "drug_affected": "4",
    "drug_at_risk": "4,650",
    "hi": "10.32",
    "lo": "0.28",
    "p": "0.56",
    "participants": "8,891",
    "placebo_affected": "2",
    "placebo_at_risk": "4,241",
    "rr": "1.71"
   },
   "half2": {
    "comparisons": "55",
    "comparisons_with_events": "6",
    "drug_affected": "6",
    "drug_at_risk": "3,470",
    "hi": "51.27",
    "lo": "0.64",
    "p": "0.12",
    "participants": "6,762",
    "placebo_affected": "1",
    "placebo_at_risk": "3,292",
    "rr": "5.73"
   },
   "leave_one_out": {
    "hi_max": "22.17",
    "lo_min": "0.63",
    "p_max": "0.19",
    "p_min": "0.060",
    "rr_max": "4.56",
    "rr_min": "2.48"
   },
   "name": "Serious suicidal behaviour, adult acute trials of SSRIs",
   "overlap_bound": "1.08",
   "p": "0.11",
   "peto": {
    "hi": "7.82",
    "lo": "0.87",
    "or": "2.60",
    "p": "0.089"
   },
   "power": {
    "hengartner_2019_attempts": "0.35",
    "kaminski_2020_attempts": "0.14",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": "0.19",
   "random_effects": {
    "hi": "3.92",
    "i2": "0.00",
    "lo": "0.63",
    "p": "0.33",
    "rr": "1.57"
   },
   "testable": true
  },
  "A12": {
   "affected": "17",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "78",
    "comparisons_with_events": "12",
    "drug_affected": "13",
    "drug_at_risk": "11,734",
    "hi": "7.84",
    "lo": "0.81",
    "p": "0.11",
    "participants": "20,674",
    "placebo_affected": "4",
    "placebo_at_risk": "8,940",
    "rr": "2.52"
   },
   "conservative_p": "0.12",
   "dominant_term": {
    "comparisons": "78",
    "comparisons_with_events": "7",
    "drug_affected": "6",
    "drug_at_risk": "11,734",
    "hi": "43.58",
    "lo": "0.48",
    "p": "0.19",
    "participants": "20,674",
    "placebo_affected": "1",
    "placebo_at_risk": "8,940",
    "rr": "4.57",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "30",
    "comparisons_with_events": "4",
    "drug_affected": "5",
    "drug_at_risk": "5,759",
    "hi": "5.32",
    "lo": "0.30",
    "p": "0.75",
    "participants": "9,922",
    "placebo_affected": "3",
    "placebo_at_risk": "4,163",
    "rr": "1.26"
   },
   "half2": {
    "comparisons": "48",
    "comparisons_with_events": "8",
    "drug_affected": "8",
    "drug_at_risk": "5,975",
    "hi": "57.46",
    "lo": "0.76",
    "p": "0.088",
    "participants": "10,752",
    "placebo_affected": "1",
    "placebo_at_risk": "4,777",
    "rr": "6.59"
   },
   "leave_one_out": {
    "hi_max": "16.87",
    "lo_min": "0.64",
    "p_max": "0.23",
    "p_min": "0.063",
    "rr_max": "3.83",
    "rr_min": "2.06"
   },
   "name": "Serious suicidal behaviour, adult acute trials of SNRIs",
   "overlap_bound": "1.06",
   "p": "0.11",
   "peto": {
    "hi": "6.06",
    "lo": "0.86",
    "or": "2.28",
    "p": "0.099"
   },
   "power": {
    "hengartner_2019_attempts": "0.43",
    "kaminski_2020_attempts": "0.17",
    "stone_2009_behaviour_25_64": "0.05"
   },
   "q": "0.19",
   "random_effects": {
    "hi": "3.31",
    "i2": "0.00",
    "lo": "0.60",
    "p": "0.42",
    "rr": "1.41"
   },
   "testable": true
  },
  "A13": {
   "affected": "6",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "41",
    "comparisons_with_events": "2",
    "drug_affected": "2",
    "drug_at_risk": "5,609",
    "hi": "2.76",
    "lo": "0.09",
    "p": "0.43",
    "participants": "10,957",
    "placebo_affected": "4",
    "placebo_at_risk": "5,348",
    "rr": "0.50"
   },
   "name": "Serious suicidal behaviour, adult acute trials of bupropion",
   "p": "0.43",
   "peto": {
    "hi": "2.57",
    "lo": "0.10",
    "or": "0.52",
    "p": "0.42"
   },
   "power": {
    "hengartner_2019_attempts": "0.18",
    "kaminski_2020_attempts": "0.09",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": null,
   "testable": false
  },
  "A14": {
   "affected": "13",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "27",
    "comparisons_with_events": "6",
    "drug_affected": "9",
    "drug_at_risk": "2,999",
    "hi": "6.93",
    "lo": "0.63",
    "p": "0.23",
    "participants": "5,591",
    "placebo_affected": "4",
    "placebo_at_risk": "2,592",
    "rr": "2.09"
   },
   "conservative_p": "0.25",
   "dominant_term": {
    "comparisons": "27",
    "comparisons_with_events": "5",
    "drug_affected": "7",
    "drug_at_risk": "2,999",
    "hi": "5.74",
    "lo": "0.48",
    "p": "0.42",
    "participants": "5,591",
    "placebo_affected": "4",
    "placebo_at_risk": "2,592",
    "rr": "1.67",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "16",
    "comparisons_with_events": "3",
    "drug_affected": "3",
    "drug_at_risk": "1,418",
    "hi": "28.04",
    "lo": "0.27",
    "p": "0.40",
    "participants": "2,810",
    "placebo_affected": "1",
    "placebo_at_risk": "1,392",
    "rr": "2.74"
   },
   "half2": {
    "comparisons": "11",
    "comparisons_with_events": "3",
    "drug_affected": "6",
    "drug_at_risk": "1,581",
    "hi": "7.63",
    "lo": "0.46",
    "p": "0.38",
    "participants": "2,781",
    "placebo_affected": "3",
    "placebo_at_risk": "1,200",
    "rr": "1.88"
   },
   "leave_one_out": {
    "hi_max": "48.10",
    "lo_min": "0.45",
    "p_max": "0.47",
    "p_min": "0.13",
    "rr_max": "5.39",
    "rr_min": "1.59"
   },
   "name": "Serious suicidal behaviour, adult acute trials of novel-mechanism antidepressants",
   "overlap_bound": "1.08",
   "p": "0.23",
   "peto": {
    "hi": "6.02",
    "lo": "0.66",
    "or": "2.00",
    "p": "0.22"
   },
   "power": {
    "hengartner_2019_attempts": "0.34",
    "kaminski_2020_attempts": "0.14",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": "0.28",
   "random_effects": {
    "hi": "4.21",
    "i2": "0.00",
    "lo": "0.53",
    "p": "0.44",
    "rr": "1.50"
   },
   "testable": true
  },
  "A15": {
   "affected": "8",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "49",
    "comparisons_with_events": "6",
    "drug_affected": "4",
    "drug_at_risk": "6,256",
    "hi": "2.60",
    "lo": "0.11",
    "p": "0.43",
    "participants": "10,721",
    "placebo_affected": "4",
    "placebo_at_risk": "4,465",
    "rr": "0.53"
   },
   "name": "Serious suicidal behaviour, adult acute trials of tricyclic, MAOI and other monoaminergic antidepressants",
   "p": "0.43",
   "peto": {
    "hi": "2.40",
    "lo": "0.13",
    "or": "0.55",
    "p": "0.42"
   },
   "power": {
    "hengartner_2019_attempts": "0.23",
    "kaminski_2020_attempts": "0.10",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": null,
   "testable": false
  },
  "A16": {
   "affected": "65",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": true,
    "increase": true
   },
   "all": {
    "comparisons": "340",
    "comparisons_with_events": "43",
    "drug_affected": "46",
    "drug_at_risk": "48,900",
    "hi": "3.27",
    "lo": "1.06",
    "p": "0.030",
    "participants": "86,606",
    "placebo_affected": "19",
    "placebo_at_risk": "37,706",
    "rr": "1.86"
   },
   "conservative_p": "0.044",
   "dominant_term": {
    "comparisons": "340",
    "comparisons_with_events": "31",
    "drug_affected": "27",
    "drug_at_risk": "48,900",
    "hi": "3.20",
    "lo": "0.79",
    "p": "0.19",
    "participants": "86,606",
    "placebo_affected": "13",
    "placebo_at_risk": "37,706",
    "rr": "1.59",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "166",
    "comparisons_with_events": "18",
    "drug_affected": "15",
    "drug_at_risk": "25,487",
    "hi": "2.52",
    "lo": "0.48",
    "p": "0.83",
    "participants": "45,624",
    "placebo_affected": "10",
    "placebo_at_risk": "20,137",
    "rr": "1.09"
   },
   "half2": {
    "comparisons": "174",
    "comparisons_with_events": "25",
    "drug_affected": "31",
    "drug_at_risk": "23,413",
    "hi": "6.19",
    "lo": "1.26",
    "p": "0.012",
    "participants": "40,982",
    "placebo_affected": "9",
    "placebo_at_risk": "17,569",
    "rr": "2.79"
   },
   "leave_one_out": {
    "hi_max": "3.79",
    "lo_min": "0.998",
    "p_max": "0.051",
    "p_min": "0.014",
    "rr_max": "2.08",
    "rr_min": "1.76"
   },
   "name": "Serious suicidal behaviour, adult acute trials, with combination products included",
   "overlap_bound": "1.16",
   "p": "0.030",
   "peto": {
    "hi": "2.91",
    "lo": "1.06",
    "or": "1.76",
    "p": "0.028"
   },
   "power": {
    "hengartner_2019_attempts": "0.93",
    "kaminski_2020_attempts": "0.50",
    "stone_2009_behaviour_25_64": "0.08"
   },
   "q": "0.076",
   "random_effects": {
    "hi": "1.90",
    "i2": "0.00",
    "lo": "0.78",
    "p": "0.38",
    "rr": "1.22"
   },
   "testable": true
  },
  "A17": {
   "affected": "1",
   "all": {
    "comparisons": "13",
    "comparisons_with_events": "1",
    "drug_affected": "1",
    "drug_at_risk": "1,935",
    "hi": null,
    "lo": null,
    "p": null,
    "participants": "3,425",
    "placebo_affected": "0",
    "placebo_at_risk": "1,490",
    "rr": null
   },
   "name": "Serious suicidal behaviour, adult randomized-withdrawal trials",
   "p": "0.55",
   "peto": {
    "hi": "336.43",
    "lo": "0.04",
    "or": "3.87",
    "p": "0.55"
   },
   "power": {
    "hengartner_2019_attempts": "0.06",
    "kaminski_2020_attempts": "0.04",
    "stone_2009_behaviour_25_64": "0.03"
   },
   "q": null,
   "testable": false
  },
  "A18": {
   "affected": "19",
   "against": {
    "decrease": false,
    "excludes_stone_2009_behaviour_under_25": false,
    "increase": false
   },
   "all": {
    "comparisons": "30",
    "comparisons_with_events": "9",
    "drug_affected": "14",
    "drug_at_risk": "4,547",
    "hi": "3.22",
    "lo": "0.43",
    "p": "0.76",
    "participants": "7,094",
    "placebo_affected": "5",
    "placebo_at_risk": "2,547",
    "rr": "1.17"
   },
   "conservative_p": "0.79",
   "dominant_term": {
    "comparisons": "30",
    "comparisons_with_events": "8",
    "drug_affected": "6",
    "drug_at_risk": "4,547",
    "hi": "2.24",
    "lo": "0.18",
    "p": "0.47",
    "participants": "7,094",
    "placebo_affected": "4",
    "placebo_at_risk": "2,547",
    "rr": "0.63",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "18",
    "comparisons_with_events": "5",
    "drug_affected": "9",
    "drug_at_risk": "2,284",
    "hi": "3.07",
    "lo": "0.30",
    "p": "0.94",
    "participants": "3,635",
    "placebo_affected": "4",
    "placebo_at_risk": "1,351",
    "rr": "0.95"
   },
   "half2": {
    "comparisons": "12",
    "comparisons_with_events": "4",
    "drug_affected": "5",
    "drug_at_risk": "2,263",
    "hi": "16.75",
    "lo": "0.24",
    "p": "0.52",
    "participants": "3,459",
    "placebo_affected": "1",
    "placebo_at_risk": "1,196",
    "rr": "2.01"
   },
   "leave_one_out": {
    "hi_max": "5.42",
    "lo_min": "0.34",
    "p_max": "0.98",
    "p_min": "0.50",
    "rr_max": "1.49",
    "rr_min": "0.95"
   },
   "name": "Serious suicidal behaviour, pediatric acute trials",
   "overlap_bound": "1.27",
   "p": "0.76",
   "peto": {
    "hi": "3.15",
    "lo": "0.43",
    "or": "1.17",
    "p": "0.76"
   },
   "power": {
    "stone_2009_behaviour_under_25": "0.41"
   },
   "q": "0.76",
   "random_effects": {
    "hi": "2.12",
    "i2": "0.00",
    "lo": "0.35",
    "p": "0.74",
    "rr": "0.86"
   },
   "testable": true
  },
  "A19": {
   "affected": "46",
   "against": {
    "decrease": false,
    "excludes_hammad_2006_pediatric_suicidality": false,
    "excludes_stone_2009_suicidality_under_25": false,
    "increase": true
   },
   "all": {
    "comparisons": "30",
    "comparisons_with_events": "14",
    "drug_affected": "38",
    "drug_at_risk": "4,547",
    "hi": "5.16",
    "lo": "1.13",
    "p": "0.023",
    "participants": "7,094",
    "placebo_affected": "8",
    "placebo_at_risk": "2,547",
    "rr": "2.41"
   },
   "conservative_p": "0.044",
   "dominant_term": {
    "comparisons": "30",
    "comparisons_with_events": "11",
    "drug_affected": "23",
    "drug_at_risk": "4,547",
    "hi": "17.19",
    "lo": "1.31",
    "p": "0.018",
    "participants": "7,094",
    "placebo_affected": "3",
    "placebo_at_risk": "2,547",
    "rr": "4.74",
    "term": "suicidal ideation"
   },
   "half1": {
    "comparisons": "18",
    "comparisons_with_events": "7",
    "drug_affected": "20",
    "drug_at_risk": "2,284",
    "hi": "4.09",
    "lo": "0.68",
    "p": "0.27",
    "participants": "3,635",
    "placebo_affected": "6",
    "placebo_at_risk": "1,351",
    "rr": "1.66"
   },
   "half2": {
    "comparisons": "12",
    "comparisons_with_events": "7",
    "drug_affected": "18",
    "drug_at_risk": "2,263",
    "hi": "21.97",
    "lo": "1.08",
    "p": "0.040",
    "participants": "3,459",
    "placebo_affected": "2",
    "placebo_at_risk": "1,196",
    "rr": "4.86"
   },
   "leave_one_out": {
    "hi_max": "6.94",
    "lo_min": "0.97",
    "p_max": "0.061",
    "p_min": "0.013",
    "rr_max": "2.87",
    "rr_min": "2.07"
   },
   "name": "Any serious suicidality, pediatric acute trials",
   "overlap_bound": "1.27",
   "p": "0.023",
   "peto": {
    "hi": "3.96",
    "lo": "1.13",
    "or": "2.12",
    "p": "0.019"
   },
   "power": {
    "hammad_2006_pediatric_suicidality": "0.58",
    "stone_2009_suicidality_under_25": "0.35"
   },
   "q": "0.076",
   "random_effects": {
    "hi": "3.33",
    "i2": "0.00",
    "lo": "0.84",
    "p": "0.14",
    "rr": "1.67"
   },
   "testable": true
  },
  "A2": {
   "affected": "60",
   "against": {
    "decrease": false,
    "excludes_stone_2009_suicidality_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "322",
    "comparisons_with_events": "34",
    "drug_affected": "36",
    "drug_at_risk": "40,564",
    "hi": "2.01",
    "lo": "0.69",
    "p": "0.54",
    "participants": "71,643",
    "placebo_affected": "24",
    "placebo_at_risk": "31,079",
    "rr": "1.18"
   },
   "conservative_p": "0.55",
   "dominant_term": {
    "comparisons": "322",
    "comparisons_with_events": "33",
    "drug_affected": "33",
    "drug_at_risk": "40,564",
    "hi": "2.25",
    "lo": "0.71",
    "p": "0.42",
    "participants": "71,643",
    "placebo_affected": "20",
    "placebo_at_risk": "31,079",
    "rr": "1.27",
    "term": "suicidal ideation"
   },
   "half1": {
    "comparisons": "156",
    "comparisons_with_events": "14",
    "drug_affected": "14",
    "drug_at_risk": "19,080",
    "hi": "2.18",
    "lo": "0.40",
    "p": "0.88",
    "participants": "33,544",
    "placebo_affected": "11",
    "placebo_at_risk": "14,464",
    "rr": "0.94"
   },
   "half2": {
    "comparisons": "166",
    "comparisons_with_events": "20",
    "drug_affected": "22",
    "drug_at_risk": "21,484",
    "hi": "2.76",
    "lo": "0.69",
    "p": "0.36",
    "participants": "38,099",
    "placebo_affected": "13",
    "placebo_at_risk": "16,615",
    "rr": "1.38"
   },
   "leave_one_out": {
    "hi_max": "2.26",
    "lo_min": "0.59",
    "p_max": "0.93",
    "p_min": "0.36",
    "rr_max": "1.30",
    "rr_min": "1.02"
   },
   "name": "Serious suicidal ideation, adult acute trials",
   "overlap_bound": "1.05",
   "p": "0.54",
   "peto": {
    "hi": "1.99",
    "lo": "0.70",
    "or": "1.18",
    "p": "0.54"
   },
   "power": {
    "stone_2009_suicidality_25_64": "0.15"
   },
   "q": "0.60",
   "random_effects": {
    "hi": "1.52",
    "i2": "0.00",
    "lo": "0.57",
    "p": "0.77",
    "rr": "0.93"
   },
   "testable": true
  },
  "A20": {
   "affected": "1",
   "all": {
    "comparisons": "19",
    "comparisons_with_events": "1",
    "drug_affected": "1",
    "drug_at_risk": "816",
    "hi": null,
    "lo": null,
    "p": null,
    "participants": "1,612",
    "placebo_affected": "0",
    "placebo_at_risk": "796",
    "rr": null
   },
   "name": "Serious suicidal behaviour, acute trials spanning adolescents and adults",
   "p": "0.34",
   "peto": {
    "hi": "338.18",
    "lo": "0.13",
    "or": "6.67",
    "p": "0.34"
   },
   "power": {
    "stone_2009_behaviour_under_25": "0.06"
   },
   "q": null,
   "testable": false
  },
  "A4": {
   "affected": "7",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "322",
    "comparisons_with_events": "6",
    "drug_affected": "5",
    "drug_at_risk": "40,564",
    "hi": "9.41",
    "lo": "0.40",
    "p": "0.41",
    "participants": "71,643",
    "placebo_affected": "2",
    "placebo_at_risk": "31,079",
    "rr": "1.94"
   },
   "name": "Completed suicide, adult acute trials",
   "p": "0.41",
   "peto": {
    "hi": "8.57",
    "lo": "0.42",
    "or": "1.90",
    "p": "0.40"
   },
   "power": {
    "hengartner_2019_attempts": "0.21",
    "kaminski_2020_attempts": "0.09",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": null,
   "testable": false
  },
  "A5": {
   "affected": "70",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": true,
    "increase": true
   },
   "all": {
    "comparisons": "322",
    "comparisons_with_events": "46",
    "drug_affected": "50",
    "drug_at_risk": "40,564",
    "hi": "3.27",
    "lo": "1.12",
    "p": "0.017",
    "participants": "71,643",
    "placebo_affected": "20",
    "placebo_at_risk": "31,079",
    "rr": "1.91"
   },
   "conservative_p": "0.029",
   "dominant_term": {
    "comparisons": "322",
    "comparisons_with_events": "31",
    "drug_affected": "27",
    "drug_at_risk": "40,564",
    "hi": "3.20",
    "lo": "0.79",
    "p": "0.19",
    "participants": "71,643",
    "placebo_affected": "13",
    "placebo_at_risk": "31,079",
    "rr": "1.59",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "156",
    "comparisons_with_events": "19",
    "drug_affected": "15",
    "drug_at_risk": "19,080",
    "hi": "2.11",
    "lo": "0.43",
    "p": "0.91",
    "participants": "33,544",
    "placebo_affected": "11",
    "placebo_at_risk": "14,464",
    "rr": "0.96"
   },
   "half2": {
    "comparisons": "166",
    "comparisons_with_events": "27",
    "drug_affected": "35",
    "drug_at_risk": "21,484",
    "hi": "7.04",
    "lo": "1.48",
    "p": "0.0032",
    "participants": "38,099",
    "placebo_affected": "9",
    "placebo_at_risk": "16,615",
    "rr": "3.23"
   },
   "leave_one_out": {
    "hi_max": "3.67",
    "lo_min": "1.06",
    "p_max": "0.030",
    "p_min": "0.0080",
    "rr_max": "2.11",
    "rr_min": "1.82"
   },
   "name": "Serious suicidal behaviour or overdose of unstated intent, adult acute trials",
   "overlap_bound": "1.19",
   "p": "0.017",
   "peto": {
    "hi": "2.96",
    "lo": "1.12",
    "or": "1.82",
    "p": "0.015"
   },
   "power": {
    "hengartner_2019_attempts": "0.95",
    "kaminski_2020_attempts": "0.53",
    "stone_2009_behaviour_25_64": "0.08"
   },
   "q": "0.076",
   "random_effects": {
    "hi": "1.91",
    "i2": "0.00",
    "lo": "0.81",
    "p": "0.32",
    "rr": "1.24"
   },
   "testable": true
  },
  "A6": {
   "affected": "49",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": true,
    "increase": true
   },
   "all": {
    "comparisons": "134",
    "comparisons_with_events": "34",
    "drug_affected": "37",
    "drug_at_risk": "21,105",
    "hi": "4.36",
    "lo": "1.10",
    "p": "0.026",
    "participants": "34,345",
    "placebo_affected": "12",
    "placebo_at_risk": "13,240",
    "rr": "2.19"
   },
   "conservative_p": "0.040",
   "dominant_term": {
    "comparisons": "134",
    "comparisons_with_events": "25",
    "drug_affected": "22",
    "drug_at_risk": "21,105",
    "hi": "3.51",
    "lo": "0.70",
    "p": "0.27",
    "participants": "34,345",
    "placebo_affected": "10",
    "placebo_at_risk": "13,240",
    "rr": "1.57",
    "term": "suicide attempt"
   },
   "half1": {
    "comparisons": "68",
    "comparisons_with_events": "16",
    "drug_affected": "12",
    "drug_at_risk": "10,675",
    "hi": "2.59",
    "lo": "0.39",
    "p": "0.99",
    "participants": "17,505",
    "placebo_affected": "8",
    "placebo_at_risk": "6,830",
    "rr": "1.01"
   },
   "half2": {
    "comparisons": "66",
    "comparisons_with_events": "18",
    "drug_affected": "25",
    "drug_at_risk": "10,430",
    "hi": "15.14",
    "lo": "1.51",
    "p": "0.0077",
    "participants": "16,840",
    "placebo_affected": "4",
    "placebo_at_risk": "6,410",
    "rr": "4.79"
   },
   "leave_one_out": {
    "hi_max": "5.57",
    "lo_min": "1.01",
    "p_max": "0.047",
    "p_min": "0.011",
    "rr_max": "2.59",
    "rr_min": "2.03"
   },
   "name": "Serious suicidal behaviour, adult acute trials of depressive disorders",
   "overlap_bound": "1.17",
   "p": "0.026",
   "peto": {
    "hi": "3.56",
    "lo": "1.10",
    "or": "1.98",
    "p": "0.023"
   },
   "power": {
    "hengartner_2019_attempts": "0.84",
    "kaminski_2020_attempts": "0.38",
    "stone_2009_behaviour_25_64": "0.07"
   },
   "q": "0.076",
   "random_effects": {
    "hi": "2.08",
    "i2": "0.00",
    "lo": "0.75",
    "p": "0.40",
    "rr": "1.24"
   },
   "testable": true
  },
  "A7": {
   "affected": "9",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "97",
    "comparisons_with_events": "5",
    "drug_affected": "4",
    "drug_at_risk": "9,365",
    "hi": "2.96",
    "lo": "0.21",
    "p": "0.73",
    "participants": "17,743",
    "placebo_affected": "5",
    "placebo_at_risk": "8,378",
    "rr": "0.79"
   },
   "name": "Serious suicidal behaviour, adult acute trials of other psychiatric disorders",
   "p": "0.73",
   "peto": {
    "hi": "2.93",
    "lo": "0.21",
    "or": "0.79",
    "p": "0.73"
   },
   "power": {
    "hengartner_2019_attempts": "0.25",
    "kaminski_2020_attempts": "0.11",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": null,
   "testable": false
  },
  "A8": {
   "affected": "7",
   "against": {
    "decrease": false,
    "excludes_hengartner_2019_attempts": false,
    "excludes_kaminski_2020_attempts": false,
    "excludes_stone_2009_behaviour_25_64": false,
    "increase": false
   },
   "all": {
    "comparisons": "91",
    "comparisons_with_events": "4",
    "drug_affected": "5",
    "drug_at_risk": "10,094",
    "hi": "12.71",
    "lo": "0.48",
    "p": "0.28",
    "participants": "19,555",
    "placebo_affected": "2",
    "placebo_at_risk": "9,461",
    "rr": "2.48"
   },
   "name": "Serious suicidal behaviour, adult acute trials of non-psychiatric conditions",
   "p": "0.28",
   "peto": {
    "hi": "10.31",
    "lo": "0.53",
    "or": "2.34",
    "p": "0.26"
   },
   "power": {
    "hengartner_2019_attempts": "0.21",
    "kaminski_2020_attempts": "0.09",
    "stone_2009_behaviour_25_64": "0.04"
   },
   "q": null,
   "testable": false
  },
  "A9": {
   "affected": "0",
   "all": {
    "comparisons": "15",
    "comparisons_with_events": "0",
    "drug_affected": "0",
    "drug_at_risk": "1,616",
    "hi": null,
    "lo": null,
    "p": null,
    "participants": "2,737",
    "placebo_affected": "0",
    "placebo_at_risk": "1,121",
    "rr": null
   },
   "name": "Serious suicidal behaviour, acute trials enrolling only people aged 60 or over",
   "p": null,
   "peto": {
    "hi": null,
    "lo": null,
    "or": null,
    "p": null
   },
   "power": {
    "hengartner_2019_attempts": "0.00",
    "kaminski_2020_attempts": "0.00",
    "stone_2009_behaviour_25_64": "0.00"
   },
   "q": null,
   "testable": false
  }
 },
 "secondary_significant": [],
 "trials": {
  "adult_comparisons": "322",
  "adult_depressive_participants": "34,345",
  "adult_depressive_trials": "131",
  "adult_drug": "40,564",
  "adult_median_mean_age": "44.4",
  "adult_participants": "71,643",
  "adult_placebo": "31,079",
  "adult_trials": "306",
  "adult_with_mean_age": "302",
  "comparisons": "413",
  "drug": "56,808",
  "eligible": "393",
  "found": "932",
  "participants": "99,730",
  "pediatric_median_mean_age": "13.5",
  "pediatric_participants": "7,094",
  "pediatric_trials": "30",
  "placebo": "42,922",
  "screened": "639"
 }
}